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Therapeutic efficacy of pycnogenol in experimental inflammatory bowel diseases

Publication Year: 2004 Source: Phytother Res PMID: 15742344 DOI: 10.1002/ptr.1611

Sequence analysis of the mtDNA control region of four samples (n=195) of Atlantic bonito (Sarda sarda) collected along the northern Mediterranean reveals two clades about 8.1% divergent distributed in an east-west cline that fits an isolation by distance (IBD) model. The vicariant origin of this genetic discontinuity is proposed, supported …

ErbB-1 expression in experimental model of inflammatory bowel disease in rats

Publication Year: 2004 Source: Acta Chir Iugosl PMID: 15771296 DOI: 10.2298/aci0402085t

Comment in Gastroenterol Hepatol. 2002 Nov;25(9):575. No data are available on the use of the Internet by Spanish patients with chronic diseases. AIM: To determine the extent to which patients with inflammatory bowel disease (IBD) in Barcelona (Spain) make use of the Internet and the relationship between Internet use and …

The histological diagnosis of dysplastic and neoplastic lesions in inflammatory bowel disease: a pathological perspective

Publication Year: 2004 Source: Acta Chir Iugosl PMID: 15771301 DOI: 10.2298/aci0402109u

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Therapeutic drug monitoring in patients with inflammatory bowel disease and established azathioprine therapy

Publication Year: 2004 Source: Clin Drug Investig PMID: 17523708 DOI: 10.2165/00044011-200424080-00006

BACKGROUND/AIMS: Keratin-8 (KRT8)-null mice develop spontaneous colitis and predisposition to liver injury. Human studies show that some KRT8 variants predispose to end-stage liver disease and progression and suggest that such variants might associate with UC or CD. We asked whether mutations in KRT8 or KRT19, the major intestinal keratins, are …

Isolation and purification of colon lamina propria dendritic cells from mice with colitis

Publication Year: 2004 Source: Cytotechnology PMID: 19003269 DOI: 10.1007/s10616-005-2552-6

The colonic epithelium is lined along its apical membrane with approximately 10(14) bacteria/g of tissue. Commensal bacteria outnumber mammalian cells in the gut severalfold. The reason for this degree of commensalism probably resides in the recent recognition of the microbiome as an important source of metabolic energy in the setting …

[N-Methyl-(11)C]-(11β17α)-11-[4-(dimethylamino)phenyl]-17-hydroxy-21-[4-(methylsulfonyl)phenyl]-19-norpregna-4,9-dien-20-yn-3-one

Publication Year: 2004 Source: Molecular Imaging and Contrast Agent Database (MICAD) PMID: 20641857

Glucocorticoids are members of the corticosteroid family (the other members of this family are the mineralocorticoid group of compounds, which bind to the mineralocorticoid receptors (MR)) and are often used as anti-inflammatory and immunosuppressive agents for the treatment of diseases such as arthritis, asthma, and cancer, as well as inflammatory …

(99m)Tc-(RR,SS)-4,8-diaza-3,6,6,9-tetramethylundecane-2,10-dione bisoxime

Publication Year: 2004 Source: Molecular Imaging and Contrast Agent Database (MICAD) PMID: 20641532

Timely diagnosis of cerebrovascular diseases (CVD) including stroke, transient ischemic attack, reversible ischemic neurological deficit and multi-infaract dementia etc. is important for the appropriate treatment of patients. Cerebral blood flow (CBF) imaging is a routine technique used for the diagnosis of CVD. Technetium ((99m)Tc) labeled d,l-hexamethyl propylene-amineoxime ((99m)Tc-HMPAO) is widely …

Genotype-based phenotyping heralds a new taxonomy for inflammatory bowel disease

Publication Year: 2003 Source: Curr Opin Gastroenterol PMID: 15703573 DOI: 10.1097/00001574-200307000-00002

OBJECTIVE: To review and critically evaluate research on psychosocial issues in pediatric inflammatory bowel disease (IBD) and to provide recommendations for future research. METHODS: A literature search was conducted using the Medline and PsychInfo computerized databases as well as the bibliographies of relevant articles. RESULTS: Most of the existing research …

Chronic inflammatory disorders of the gastrointestinal tract of companion animals

Publication Year: 2003 Source: N Z Vet J PMID: 16032340 DOI: 10.1080/00480169.2003.36380

The chronic idiopathic inflammatory bowel diseases (IBDs), namely Crohn's disease and ulcerative colitis, appear to be derived from an inappropriate reaction towards a luminal agent, most probably driven by the intestinal microflora, which upregulates the synthesis and release of different pro-inflammatory mediators, thus contributing to tissue damage that characterizes these …

Stratification by CARD15 variant genotype in a genome-wide search for inflammatory bowel disease susceptibility loci

Publication Year: 2003 Source: Hum Genet PMID: 13680363 DOI: 10.1007/s00439-003-1020-7

INTRODUCTION: Inflammatory bowel diseases are chronic conditions that might cause a severe impact on social life. The aim of the study was to assess employment, chronic work disability, and sick leave in patients with inflammatory bowel disease. METHODS: A postal questionnaire was sent to 984 patients with inflammatory bowel disease …

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