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Vascular endothelial growth factor in inflammatory bowel disease
Publication Year: 2003 Source: Int J Colorectal Dis PMID: 12761641 DOI: 10.1007/s00384-003-0495-y
BACKGROUND: A widespread increase in the use of complementary alternative medicine (CAM) by patients with inflammatory bowel disease (IBD) has been recognized. The aim of our study was to evaluate both the extent and the determinants of CAM use by outpatients with IBD. METHODS: Outpatients of the IBD centre at …
Home total parenteral nutrition: an alternative to early surgery for complicated inflammatory bowel disease
Publication Year: 2003 Source: J Gastrointest Surg PMID: 12763417 DOI: 10.1016/S1091-255X(02)00132-4
Comment in Am J Hum Genet. 2002 Aug;71(2):217-22. We present a new method of quantitative-trait linkage analysis that combines the simplicity and robustness of regression-based methods and the generality and greater power of variance-components models. The new method is based on a regression of estimated identity-by-descent (IBD) sharing between relative …
Mouse models for the study of Crohn's disease
Publication Year: 2003 Source: Trends Mol Med PMID: 12763527 DOI: 10.1016/s1471-4914(03)00052-2
Metallothioneins (MT) are ubiquitous found in eukaryotic organism. MT have a potential for metal-storage and protect the cells against stress. On the genomic level, proinflammatory cytokines like interleukin-6 and transition metals like copper cause induction of MT. Therefore, an estimation of MT in liver-biopsies from patients with different diseases probably …
Diagnostic accuracy of fecal calprotectin assay in distinguishing organic causes of chronic diarrhea from irritable bowel syndrome: a prospective study in adults and children
Publication Year: 2003 Source: Clin Chem PMID: 12765980 DOI: 10.1373/49.6.861
This paper examines the safety and feasibility of providing short-term, in-home total parenteral nutrition (TPN) for patients with inflammatory bowel disease (IBD) for whom the alternative is prolonged hospitalization or early surgery. The records of all patients with IBD who were receiving temporary home TPN between June 1996 and July …
Hypervalent iodine mediated synthesis of 1-aryl/hetryl-1,2,4-triazolo[4,3-a] pyridines and 1-aryl/hetryl 5-methyl-1,2,4-triazolo[4,3-a]quinolines as antibacterial agents
Publication Year: 2003 Source: Eur J Med Chem PMID: 12767604 DOI: 10.1016/s0223-5234(03)00061-8
Over the past years, a number of idiopathic, chronic, inflammatory gastrointestinal diseases have been recognized, which can be distinguished from Crohn's disease and ulcerative colitis. These entities are grouped under the term "variant forms" of IBD. In this review, three distinctive, variant-IBD entities--all of which with individual and uniform histories …
Pulmonary manifestations of inflammatory bowel disease
Publication Year: 2003 Source: Inflamm Bowel Dis PMID: 12769444 DOI: 10.1097/00054725-200303000-00004
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Cytokine and anti-cytokine therapies for inflammatory bowel disease
Publication Year: 2003 Source: Curr Pharm Des PMID: 12769750 DOI: 10.2174/1381612033455035
BACKGROUND AND AIM: There is controversy regarding whether paramyxovirus infection is causally associated with inflammatory bowel disease (IBD). The latest cohort study claimed that atypical measles and mumps infections in childhood may be risk factors for later IBD. This study was conducted to clarify the validity of a causal link …
Curcumin, the major component of food flavour turmeric, reduces mucosal injury in trinitrobenzene sulphonic acid-induced colitis
Publication Year: 2003 Source: Br J Pharmacol PMID: 12770926 DOI: 10.1038/sj.bjp.0705241
BACKGROUND: Variants of the caspase activating recruitment domain 15/nucleotide oligomerisation domain 2 (CARD15/NOD2) gene have been associated with susceptibility to Crohn's disease (CD). AIM: Our aim was to evaluate the allele frequencies of the CARD15 variants R702W, G908R, and 1007fs in Finnish inflammatory bowel disease (IBD) patients and to search …
6-mercaptopurine and inflammatory bowel disease: hidden ground for the cytomegalovirus
Publication Year: 2003 Source: Can J Gastroenterol PMID: 12772006 DOI: 10.1155/2003/824547
Although [99mTc]HMPAO-labeled leukocyte scintigraphy is widely used in the assessment of IBD, the time point chosen for imaging is still controversial. The aim of the present study was to determine the optimal scanning sequence to assess IBD extension and activity. Sixty-two consecutive patients with active and 18 with inactive IBD …
Current indications for blow-hole colostomy:ileostomy procedure. A single center experience
Publication Year: 2003 Source: Int J Colorectal Dis PMID: 12774252 DOI: 10.1007/s00384-002-0453-0
BACKGROUND AND AIMS: We investigated the coexistence of dehydroepiandrosterone sulfate (DHEAS) and testosterone deficiency in men with inflammatory bowel disease (IBD) and their relationship with bone homeostasis. PATIENT AND METHODS: In 45 men with IBD (25 with ulcerative colitis, 20 with Crohn's disease) the testosterone and DHEAS levels were examined …
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