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A scoring index for disease activity in canine inflammatory bowel disease
Publication Year: 2003 Source: J Vet Intern Med PMID: 12774968 DOI: 10.1111/j.1939-1676.2003.tb02450.x
PURPOSE: Some patients with nonmalignant systemic diseases, like collagen vascular disease (CVD), hypertension, diabetes mellitus, and inflammatory bowel disease (IBD), tolerate radiation therapy poorly. Although the mechanisms of each of these disease processes are different, they share a common microvessel pathology that is potentially exacerbated by radiotherapy. This article reviews …
Feline epitheliotropic intestinal malignant lymphoma: 10 cases (1997-2000)
Publication Year: 2003 Source: J Vet Intern Med PMID: 12774974 DOI: 10.1111/j.1939-1676.2003.tb02456.x
BACKGROUND AND AIMS: Dextran sulfate sodium (DSS) induced colitis exhibits a predominantly NF-kappaB dependent proinflammatory cytokine profile and shares similarities with human inflammatory bowel disease (IBD). Lamina propria macrophages of IBD patients display elevated levels of NF-kappaB p65. Knowing the role of NF-kappaB in IBD, we investigated the beneficial cellular …
IBD5 is a general risk factor for inflammatory bowel disease: replication of association with Crohn disease and identification of a novel association with ulcerative colitis
Publication Year: 2003 Source: Am J Hum Genet PMID: 12776251 DOI: 10.1086/376417
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Improvement of inflammatory bowel disease after allogeneic stem-cell transplantation
Publication Year: 2003 Source: Transplantation PMID: 12777867 DOI: 10.1097/01.TP.0000062540.29757.E9
The clinical, histopathologic, and immunohistochemical features of 10 cats with epitheliotropic intestinal malignant lymphoma (EIL) are described. Intestinal biopsy samples were reviewed by 3 pathologists to confirm the diagnosis of EIL. These samples (n = 10) were compared to the intestinal biopsies of normal cats (n = 11), cats with …
[Chronic intestinal diseases in the dog: a review]
Publication Year: 2003 Source: Schweiz Arch Tierheilkd PMID: 12784482 DOI: 10.1024/0036-7281.145.5.209
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Review article: medical treatment of mild to moderately active Crohn's disease
Publication Year: 2003 Source: Aliment Pharmacol Ther PMID: 12786608 DOI: 10.1046/j.1365-2036.17.s2.22.x
Patient education especially groups for patients with inflammatory bowel disease belong to the typical tasks of Reha-medicine. In the Reha-Clinic "Ob der Tauber", Bad Mergentheim these patients are informed in special Colitis/Crohn-groups for eleven years now. Normally approximately ten patients with IBD are treated in our house at the same …
Genetic variation in the IGSF6 gene and lack of association with inflammatory bowel disease
Publication Year: 2003 Source: Eur J Immunogenet PMID: 12786995 DOI: 10.1046/j.1365-2370.2003.00387.x
BACKGROUND & AIMS: The technique of genomewide scanning has been applied successfully in inflammatory bowel disease (IBD). A number of putative susceptibility loci have been identified through genomewide searches including replicated regions of linkage on chromosomes 12, 16, 6 (the HLA region), and 14. We have investigated the contribution of …
A national survey on the patterns of treatment of inflammatory bowel disease in Canada
Publication Year: 2003 Source: BMC Gastroenterol PMID: 12791168 DOI: 10.1186/1471-230X-3-10
BACKGROUND & AIMS: Platelets circulate in an activated state in patients with inflammatory bowel disease (IBD), but their role in the pathogenesis of IBD is unclear. The recent demonstration that activated platelets express CD40 ligand (L) provides a mechanism of interaction with CD40-positive endothelial cells, inducing them to produce proinflammatory …
Challenges in IBD Research: updating the scientific agendas
Publication Year: 2003 Source: Inflamm Bowel Dis PMID: 12792219 DOI: 10.1097/00054725-200305000-00001
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Evidence of active cytomegalovirus infection and increased production of IL-6 in tissue specimens obtained from patients with inflammatory bowel diseases
Publication Year: 2003 Source: Inflamm Bowel Dis PMID: 12792220 DOI: 10.1097/00054725-200305000-00002
Interleukin (IL)-18 is a cytokine with a broad array of effector functions, the most prominent of which is to act synergistically with IL-12 in interferon-gamma production and the induction of a strong T-helper-1-mediated immune response. In addition, IL-18 also upregulates the production of proinflammatory cytokines such as IL-1 and tumor …
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