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Maternal correlates of health status in adolescents with inflammatory bowel disease

Publication Year: 2002 Source: J Psychosom Res PMID: 11897236 DOI: 10.1016/s0022-3999(01)00291-4

BACKGROUND: Amyloidosis (A) is a well-known but rare complication to inflammatory bowel disease (IBD). We describe 18 patients with IBD and A, with special emphasis on clinicopathologic features and site relationships, comparing our results with previously reported cases in the world literature. METHODS: Patient records were collected from the files …

Nuclear receptors. I. PPAR gamma in the gastrointestinal tract: gain or pain?

Publication Year: 2002 Source: Am J Physiol Gastrointest Liver Physiol PMID: 11897616 DOI: 10.1152/ajpgi.00508.2001

Not found

rHuKGF ameliorates symptoms in DSS and CD4(+)CD45RB(Hi) T cell transfer mouse models of inflammatory bowel disease

Publication Year: 2002 Source: Am J Physiol Gastrointest Liver Physiol PMID: 11897629 DOI: 10.1152/ajpgi.00314.2001

OBJECTIVE: To report the results of sentinel lymph node biopsy (SLNB) for cutaneous head and neck melanomas (CMHNs). DESIGN: Consecutive series followed for a median of 20 months. SETTING: Tertiary cancer care center. PATIENTS: Fifty-six individuals with clinically node-negative CMHN, median Breslow thickness, 2.6 mm (range, 0.2-20.0 mm). INTERVENTIONS: Preoperative …

The linkage information content value of polymorphism genetic markers in model-free linkage analysis

Publication Year: 2002 Source: Hum Hered PMID: 11901271 DOI: 10.1159/000048604

Latent class (LCA) and cluster analysis (CLA) were utilized to identify trait loci for the Genetic Analysis Workshop 12 simulated disease. These techniques create non-overlapping subsets of concordant and discordant affected relative pairs based upon identity-by-descent (IBD) allele sharing at sequences of markers. Subgroups with a large proportion of affected …

Polymorphisms of the TNF gene and the TNF receptor superfamily member 1B gene are associated with susceptibility to ulcerative colitis and Crohn's disease, respectively

Publication Year: 2002 Source: Immunogenetics PMID: 11904678 DOI: 10.1007/s00251-001-0423-7

The imbalance between Th1 pro-inflammatory and Th2 anti-inflammatory cytokine-producing cells plays a major role in the pathogenesis of inflammatory bowel disease (IBD). Induction of oral tolerance to colitis-extracted proteins was previously shown to down-regulate the anti-colon immune response, thereby alleviating experimental colitis. Immune bystander effect and liver-associated lymphocytes expressing the …

Update in medical therapy of ulcerative colitis: a practical approach

Publication Year: 2002 Source: J Clin Gastroenterol PMID: 11907350 DOI: 10.1097/00004836-200204000-00004

In the last decade, substantial gains have been made in the treatment of inflammatory bowel disease (IBD). Refinements in drug formulation have provided the ability to target distinct sites of delivery, enhancing the safety and efficacy of older agents. Immunosuppressive agents beyond corticosteroids have assumed a routine part in the …

6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease

Publication Year: 2002 Source: Gastroenterology PMID: 11910342 DOI: 10.1053/gast.2002.32420

The gum resin extract from Boswellia serrata (H15), an herbal product, was recently shown to have positive therapeutic effects in inflammatory bowel disease (IBD). However, the mechanisms and constituents responsible for these effects are poorly understood. This study examined the effect of the Boswellia extract and its single constituent acetyl-11-keto-beta-boswellic …

Post-liver transplant Crohn's disease: graft tolerance but not self-tolerance?

Publication Year: 2002 Source: Dig Dis Sci PMID: 11911336 DOI: 10.1023/a:1017951632444

Not found

Neuropeptides and nerve growth in inflammatory bowel diseases: a quantitative immunohistochemical study

Publication Year: 2002 Source: Dig Dis Sci PMID: 11913410 DOI: 10.1023/a:1017943430627

Prompt and appropriate referrals to colorectal surgeons result in better clinical and more cost-effective outcome: the question that then arises is how patients with large bowel diseases get in contact with the specialist. The aim of the present research was to investigate the sources of clinical referrals of 1000 patients …

Inflammatory bowel disease evaluated by low-field magnetic resonance imaging. Comparison with endoscopy, 99mTc-HMPAO leucocyte scintigraphy, conventional radiography and surgery

Publication Year: 2002 Source: Scand J Gastroenterol PMID: 11916193 DOI: 10.1080/003655202317284219

BACKGROUND & AIMS: There is a subtle distinction between sporadic colorectal adenomas and cancers (SAC) and inflammatory bowel disease (IBD)-associated dysplasias and cancers. However, this distinction is clinically important because sporadic adenomas are usually managed by polypectomy alone, whereas IBD-related high-grade dysplasias mandate subtotal colectomy. The current study evaluated the …

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