Research Articles Library
Literature Analysis Tools
Advanced Search
Filter by PMID, year, source, DOI and other criteria
Literature Analysis
Analyze research trends and hotspots
Batch Export
Export search results to Excel/PDF
Health-related quality of life and psychological distress in a population-based sample of Swedish patients with inflammatory bowel disease
Publication Year: 2002 Source: Scand J Gastroenterol PMID: 11989837 DOI: 10.1080/003655202317316097
Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the intestine and/or colon of unknown etiology in which patients suffer from severe diarrhea, rectal bleeding, abdominal pain, fever, and weight loss. Active episodes of IBD are characterized by vasodilation, venocongestion, edema, infiltration of large numbers of inflammatory cells, and …
The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease
Publication Year: 2002 Source: J Exp Med PMID: 11994418 DOI: 10.1084/jem.20011956
The present studies were designed to determine whether recombinant human growth hormone (rhGH) can counteract some of the catabolic effects of glucocorticosteroid therapy in children chronically treated with glucocorticosteroids. Whether rhGH can safely improve short-term linear growth was also investigated. The effect of rhGH on disease activity was also assessed. …
p38 mitogen-activated protein kinase is activated and linked to TNF-alpha signaling in inflammatory bowel disease
Publication Year: 2002 Source: J Immunol PMID: 11994493 DOI: 10.4049/jimmunol.168.10.5342
Not found
Statistics on continuous IBD data: exact distribution evaluation for a pair of full(half)-sibs and a pair of a (great-) grandchild with a (great-) grandparent
Publication Year: 2002 Source: BMC Genet PMID: 11996673 DOI: 10.1186/1471-2156-3-7
Comment in Lancet. 2001 Jan 27;357(9252):246-7. BACKGROUND: Inflammatory bowel disease (IBD) and colorectal cancer might share a common cause and, therefore, relatives of patients with IBD could be at increased risk of this malignant disease. We aimed to assess cancer rates among first-degree relatives of patients with IBD to try …
A critical assessment of new therapies in inflammatory bowel disease
Publication Year: 2002 Source: J Gastroenterol Hepatol PMID: 12000604 DOI: 10.1046/j.1440-1746.17.s1.1.x
Inflammatory bowel diseases (IBD) representing both Crohn's disease and ulcerative colitis are characterized by chronic activation of macrophages. Natural resistance-associated macrophage protein 1 (NRAMP1) gene regulates macrophage activation of antimicrobial activity and has many pleiotropic effects on macrophage functions. To explore the role of the NRAMP1 gene in IBD susceptibility, …
Measuring quality of life in children with inflammatory bowel disease: the impact-II (NL)
Publication Year: 2002 Source: Qual Life Res PMID: 12003055 DOI: 10.1023/a:1014455702807
BACKGROUND: Traditionally important components of the surgical clerkship curriculum include lectures, small-group sessions, readings, clinical exposure, and testing. Time constraints require compromise among all these elements. At our institution, clinical exposure of medical students varies according to their team assignments. They differ primarily in exposure to such topics as trauma, …
Using COX-2 inhibitors in IBD: anti-inflammatories inflame a controversy
Publication Year: 2002 Source: Am J Gastroenterol PMID: 12003408 DOI: 10.1111/j.1572-0241.2002.05592.x
Comment on Gut. 2002 Apr;50(4):507-12.
Immunomodulatory therapy for pediatric inflammatory bowel disease: changing patterns of use, 1990-2000
Publication Year: 2002 Source: Am J Gastroenterol PMID: 12003428 DOI: 10.1111/j.1572-0241.2002.05611.x
OBJECTIVE: The aim of this study was to ascertain GPs' views about open access to out-patient follow-up for patients with inflammatory bowel disease (IBD). METHODS: Semi-structured interviews and a postal survey were carried out in general practices in West Glamorgan UK, each with at least one IBD patient taking part …
Melatonin reduces TNF-a induced expression of MAdCAM-1 via inhibition of NF-kappaB
Publication Year: 2002 Source: BMC Gastroenterol PMID: 12003644 DOI: 10.1186/1471-230x-2-9
This study investigated faecal calprotectin concentration, a measure of intestinal inflammation, in infants and children with abdominal pain. Faecal calprotectin was measured by an enzyme-linked immunosorbent assay kit in spot stool samples in 76 infants with typical infantile colic, 7 infants with transient lactose intolerance and 27 healthy infants. All …
Cancer in Inflammatory Bowel Disease
Publication Year: 2002 Source: Curr Treat Options Gastroenterol PMID: 12003711 DOI: 10.1007/s11938-002-0038-6
Nuclear factor (NF) kappa B is a transcription factor that controls the transcription of a variety of cellular genes regulating the inflammatory response. Many proinflammatory cytokines are transcriptionally regulated by NF-kappa B, and their increased expression has been implicated in the pathogenesis of inflammatory bowel disease (IBD). Even though it …
Need more literature?
The current database contains 98453 research articles. If you need to search for more literature or perform AI analysis, please use our knowledge acquisition module or explore external literature resources.
External Resources: Access comprehensive literature databases worldwide