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Multipoint estimation of identity-by-descent probabilities at arbitrary positions among marker loci on general pedigrees

Publication Year: 2001 Source: Hum Hered PMID: 11588394 DOI: 10.1159/000053366

Inflammatory bowel disease (IBD) can present with extraintestinal manifestations occasionally involving the eye. Retinal vein occlusions are rarely seen and have never been reported in the pediatric population though vascular thrombosis can be associated with IBD. Here, we present a case of what we believe is the youngest reported patient …

Primary sclerosing cholangitis in patients with inflammatory bowel disease in Turkey

Publication Year: 2001 Source: J Clin Gastroenterol PMID: 11588543 DOI: 10.1097/00004836-200110000-00008

OBJECTIVE: To characterize the mucosal IgE network in dogs affected with inflammatory bowel disease (IBD) and compare it with that for healthy dogs. ANIMALS: 9 healthy dogs and 20 dogs with IBD. PROCEDURE: In situ hybridization of mRNA specific for IgE and interleukin 4 (IL-4) and immunohistochemical analysis for IgE …

Dipeptidyl peptidase IV (DP IV, CD26) in patients with inflammatory bowel disease

Publication Year: 2001 Source: Scand J Gastroenterol PMID: 11589380 DOI: 10.1080/003655201750422675

PURPOSE: To evaluate the safety of administering fluorouracil (5FU)-based chemotherapy to cancer patients with inflammatory bowel disease (IBD). PATIENTS AND METHODS: We retrospectively reviewed all patients entered into the Memorial Sloan-Kettering Cancer Center clinical data base from 1985 through 1995 who had a diagnosis of IBD, had a gastrointestinal malignancy, …

Rectal nitric oxide assessment in children with Crohn disease and ulcerative colitis. Indicator of ileocaecal and colorectal affection

Publication Year: 2001 Source: Scand J Gastroenterol PMID: 11589381 DOI: 10.1080/003655201750422684

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Pediatric "PSC-IBD": a descriptive report of associated inflammatory bowel disease among pediatric patients with psc

Publication Year: 2001 Source: J Pediatr Gastroenterol Nutr PMID: 11593125 DOI: 10.1097/00005176-200109000-00013

At the present there are no large-scale epidemiologic data on inflammatory bowel disease (IBD) in the Asia-Pacific region, but several studies have shown an increased incidence and prevalence of IBD in this region. Compared to the West, there appears to exist a time lag phenomenon. With regard to the two …

Prevalence of the factor V Leiden mutation in human inflammatory bowel disease with different activity

Publication Year: 2001 Source: J Physiol Paris PMID: 11595479 DOI: 10.1016/s0928-4257(01)00067-5

BACKGROUND: The association between smoking and inflammatory bowel disease (IBD) is well established. There are, however, no large scale studies of passive smoking in inflammatory bowel disease and this has never been surveyed in the Jewish population of Israel. AIM: To study the passive smoking exposure of Jewish IBD patients …

Capsaicin as a source for painful stimulation in functional MRI

Publication Year: 2001 Source: J Magn Reson Imaging PMID: 11599056 DOI: 10.1002/jmri.1192

The article reviews cardiac magnetic resonance spectroscopy (MRS) in Canada. 31P MRS has been used to study cardiac energetics and intracellular pH in hearts subjected to ischemia-reperfusion and to evaluate the effects of pharmacological interventions. 23Na, 87Rb, and 7Li MRS have provided unique probes to study ion balance and fluxes …

Allelic variation at the interleukin 1beta gene is associated with decreased bone mass in patients with inflammatory bowel diseases

Publication Year: 2001 Source: Gut PMID: 11600466 DOI: 10.1136/gut.49.5.644

Low bone mineral density and the increased risk of fracture in gastrointestinal diseases have a multifactorial pathogenesis. Inflammatory bowel disease (IBD) has been associated with an increased risk of osteoporosis and osteopenia and epidemiologic studies have reported an increased prevalence of low bone mass in patients with IBD. Certainly, genetics …

Dysfunctional LAD-1 neutrophils and colitis

Publication Year: 2001 Source: Gastroenterology PMID: 11606509 DOI: 10.1053/gast.2001.28022

BACKGROUND: Experimental colitis with features similar to inflammatory bowel disease (IBD) has initially been described. A detailed analysis of inflammatory cells has not yet been described. Therefore in this study we characterized the cells involved in the acute phase of the colitis and compared those findings to what is known …

Dextran sulphate sodium-induced colitis is ameliorated in interleukin 4 deficient mice

Publication Year: 2001 Source: Genes Immun PMID: 11607786 DOI: 10.1038/sj.gene.6363782

During an attack of ulcerative colitis the colonic pH of normally 6.4-7.0 drops to values of 2.3-4.7. The objective of this study was to investigate an acid-soluble polymer (Eudragit E) as coating material for multiple units (mini tablets) with regard to its ability to allow drug release only under the …

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