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Concerns of patients with inflammatory bowel disease: results from a clinical population

Publication Year: 2001 Source: Am J Gastroenterol PMID: 11419835 DOI: 10.1111/j.1572-0241.2001.03877.x

There is much interest in use of identity-by-descent (IBD) methods to map genes, both in Mendelian and in complex disorders. Homozygosity mapping provides a rapid means of mapping autosomal recessive genes in consanguineous families by identifying chromosomal regions that show homozygous IBD segments in pooled samples. In this report, we …

Cross-cultural variation in disease-related concerns among patients with inflammatory bowel disease

Publication Year: 2001 Source: Am J Gastroenterol PMID: 11419836 DOI: 10.1111/j.1572-0241.2001.03878.x

BACKGROUND: The purpose of this study was to evaluate retrospectively the value of leukocyte-labeled scintigraphy, ultrasonography, and contrast radiography compared with endoscopy in children suspected of having inflammatory bowel disease (IBD). METHODS: Twenty-eight children (17 boys; mean age, 10.2 years) with IBD based on standard colonoscopic, histologic, and radiologic criteria …

Simultaneous occurrence of inflammatory bowel disease and thyroid disease

Publication Year: 2001 Source: Am J Gastroenterol PMID: 11419852 DOI: 10.1111/j.1572-0241.2001.03896.x

Not found

Staphylococcus aureus in inflammatory bowel disease

Publication Year: 2001 Source: Scand J Gastroenterol PMID: 11424320 DOI: 10.1080/003655201750163079

Not found

Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations

Publication Year: 2001 Source: Lancet PMID: 11425413 DOI: 10.1016/S0140-6736(00)05063-7

Comment in J Pediatr Gastroenterol Nutr. 2001 Feb;32(2):224-5. BACKGROUND: A prospective study of inflammatory bowel disease (IBD) in Sweden was performed to investigate whether the incidence and morbidity have changed from 1984 through 1995. METHODS: Children 15 years of age or less with IBD were included--i.e., those with a definite …

Quality of life in inflammatory bowel disease: a cross-cultural comparison of English and Canadian children

Publication Year: 2001 Source: J Pediatr Gastroenterol Nutr PMID: 11429519 DOI: 10.1097/00005176-200105000-00016

Comment in Am J Gastroenterol. 1999 Apr;94(4):1113. OBJECTIVES: The military history of patients with inflammatory bowel disease (IBD) contains types of exposure that are not available through other sources and may provide clues about the as-yet unknown etiology of IBD. We therefore sought to describe the epidemiology of IBD among …

Inflammatory bowel disease in the elderly

Publication Year: 2001 Source: Gastroenterol Clin North Am PMID: 11432298 DOI: 10.1016/s0889-8553(05)70188-6

Examination of how psychological factors relate to illness severity among adolescents with inflammatory bowel disease (IBD) is rare. Further, studies have not accounted for the pervasive influence of negative affectivity (NA) or distinguished among subjective, behavioral, and objective measures of IBD severity. We examined how NA, positive affectivity, expressed hostility, …

Assessment of the usefulness of a diagnostic test: a survey of patient preference for diagnostic techniques in the evaluation of intestinal inflammation

Publication Year: 2001 Source: BMC Med Res Methodol PMID: 11434868 DOI: 10.1186/1471-2288-1-5

OBJECTIVES: Gene-environment (GxE) interaction influences risk for many complex disease traits. However, genome screens using affected sib pair linkage techniques are typically conducted without regard for GxE interaction. We propose a simple extension of the commonly used mean test and evaluate its power for several forms of GxE interaction. METHODS: …

Quality of life of Greek patients with inflammatory bowel disease. Validation of the Greek translation of the inflammatory bowel disease questionnaire

Publication Year: 2001 Source: Digestion PMID: 11435724 DOI: 10.1159/000051896

Chronic inflammatory bowel disease (IBD)-like colitis is occasionally associated with glycogen storage disease-type 1b (GSD-1b). We describe a 17-year old boy with GSD-1b who developed an IBD-like colitis. Roentgenography and colonoscopy showed the lead-pipe appearance of the colon and circumferential ulcers. Histopathologic examination revealed nonspecific inflammation without granulomatous lesions. High-dose …

A functional polymorphism of the stromelysin gene (MMP-3) influences susceptibility to primary sclerosing cholangitis

Publication Year: 2001 Source: Gastroenterology PMID: 11438501 DOI: 10.1053/gast.2001.25527

BACKGROUND: Increased concentrations of nitrate and nitrite (the breakdown products of nitric oxide) in the serum and faeces of patients with inflammatory bowel disease (IBD) suggests that increased synthesis of nitric oxide occurs in IBD. The aim of this study was to assess aminoguanidine (AMG), a selective inhibitor of inducible …

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