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An investigation into the effect and mechanisms of action of nicotine in inflammatory bowel disease
Publication Year: 2000 Source: Inflamm Res PMID: 10959551 DOI: 10.1007/s000110050597
BACKGROUND: Colitis induced by trinitrobenzene sulfonic acid (TNBS) with reactivation is a good experimental model for studying inflammatory bowel disease pathogenesis and appropriate therapeutics. This experimental model allows the induction of colitis relapse and remission periods and the establishment of chronic disease features, such as the mesenteric adipose tissue alterations …
Exclusion of linkage of Crohn's disease to previously reported regions on chromosomes 12, 7, and 3 in the Belgian population indicates genetic heterogeneity
Publication Year: 2000 Source: Inflamm Bowel Dis PMID: 10961588 DOI: 10.1097/00054725-200008000-00002
OBJECTIVES: To determine the degree and determinants of the use of complementary and alternative medicine (CAM) by patients with inflammatory bowel disease (IBD) with the use of the Internet and to compare the results with those found by using a similar survey in patients attending gastroenterology clinics in Calgary, Alberta. …
Palliative care in inflammatory bowel disease: an evidence-based approach
Publication Year: 2000 Source: Inflamm Bowel Dis PMID: 10961595 DOI: 10.1097/00054725-200008000-00009
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Immunosuppressors for inflammatory bowel disease: how long is long enough?
Publication Year: 2000 Source: Inflamm Bowel Dis PMID: 10961598 DOI: 10.1097/00054725-200008000-00013
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Inflammatory bowel diseases are not associated with major hereditary conditions predisposing to thrombosis
Publication Year: 2000 Source: Dig Dis Sci PMID: 10961731 DOI: 10.1023/a:1005541028045
BACKGROUND: The effect of environmental factors has been demonstrated in the pathogenesis of inflammatory bowel disease (IBD). Nutrition may be one of them. AIM: To investigate the pre-illness diet in patients with recent IBD in comparison with matched population and clinic controls. METHODS: Quantified dietary histories were obtained from 87 …
A unified Haseman-Elston method for testing linkage with quantitative traits
Publication Year: 2000 Source: Am J Hum Genet PMID: 10961909 DOI: 10.1086/303081
The nonparametric (model-free) method of linkage analysis Weighted Pairwise Correlation (WPC) has been proposed by Commenges [1994], and extended to incorporate identity-by-descent (IBD) information [Zinn-Justin and Abel, 1999]. We performed an autosome-wide scan in the Collaborative Study on the Genetics of Alcoholism data using the WPC-IBD method, considering two phenotypes …
The effects of retrograde cardioplegia technique on myocardial perfusion and energy metabolism: a magnetic resonance imaging and localized phosphorus 31 spectroscopy study in isolated pig hearts
Publication Year: 2000 Source: J Thorac Cardiovasc Surg PMID: 10962417 DOI: 10.1067/mtc.2000.108165
Update in Cochrane Database Syst Rev. 2015;12:CD004827. Comment in Sao Paulo Med J. 2017 Nov-Dec;135(6):578-586. Update of Cochrane Database Syst Rev. 2007;(2):CD004827. BACKGROUND: Antibiotics alter the microbial balance within the gastrointestinal tract. Probiotics may prevent antibiotic-associated diarrhea (AAD) via restoration of the gut microflora. Antibiotics are prescribed frequently in children …
EC-IBD: a European effort in inflammatory bowel disease
Publication Year: 2000 Source: Eur J Intern Med PMID: 10967505 DOI: 10.1016/s0953-6205(00)00089-3
BACKGROUND AND AIMS: The use of complementary and alternative medicine (CAM) has been increasing in recent decades. Our aim was to determine the proportion of CAM use among patients with inflammatory bowel disease (IBD) in a longitudinal, population-based cohort and to identify predictive factors for CAM use. METHODS: The Inflammatory …
Changes in the incidence of inflammatory bowel disease: what does it mean?
Publication Year: 2000 Source: Eur J Intern Med PMID: 10967506 DOI: 10.1016/s0953-6205(00)00090-x
AIM: To identify the risk factors and three single nucleotide polymorphisms (SNPs) of NOD2/CARD15 gene in inflammatory bowel disease (IBD) of the population in Zhejiang, China. METHODS: A case-control study was conducted using recall questionnaire to collect data on demographic, socioeconomic, lifestyle characteristics and dietary behaviors from 136 determined IBD …
Medical treatment: does it influence the natural course of inflammatory bowel disease?
Publication Year: 2000 Source: Eur J Intern Med PMID: 10967507 DOI: 10.1016/s0953-6205(00)00091-1
Comment in Science. 2000 Aug 25;289(5483):1311-2. The cytokine interleukin-10 (IL-10) has shown promise in clinical trials for treatment of inflammatory bowel disease (IBD). Using two mouse models, we show that the therapeutic dose of IL-10 can be reduced by localized delivery of a bacterium genetically engineered to secrete the cytokine. …
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