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Cross-reactivity of TNP immune effector T cells that mediate contact hypersensitivity and inflammatory bowel disease in the mouse
Publication Year: 2000 Source: Int Arch Allergy Immunol PMID: 11146391 DOI: 10.1159/000053646
Inflammatory bowel disease (IBD) intestinal mononuclear cells (MNC) exhibit decreased spontaneous IgA secretion with an increased percentage of monomeric IgA and IgA subclass 1 in both ulcerative colitis and Crohn's disease patients. When compared with control intestinal MNC, a marked increase in spontaneous secretion of IgG is observed from IBD …
Immune responses to intermediate strain IBD vaccine at different levels of maternal antibody in broiler chickens
Publication Year: 2000 Source: Trop Anim Health Prod PMID: 11147275 DOI: 10.1023/a:1005225501513
BACKGROUND AND AIMS: The neutrophil protein calprotectin has been investigated as a surrogate marker for intestinal inflammation. This study was designed to contrast fecal calprotectin levels in patients with inflammatory and non-inflammatory intestinal diseases and to compare the results obtained from the standard ELISA-based method with those obtained from a …
Subclinical sacroiliitis in inflammatory bowel disease: a clinical and follow-up study
Publication Year: 2000 Source: Clin Rheumatol PMID: 11147753 DOI: 10.1007/s100670070003
Susceptibility to inflammatory bowel disease (IBD) is significantly determined by genetic factors. Linkage data from genome-wide searches have identified regions on chromosomes 16, 12, 7, and 3. Our goal was to replicate these four regions in a Belgian population of IBD families. Fifty-four IBD families were studied (47 with Crohn's …
Timing of surgery for enterovesical fistula in Crohn's disease: decision analysis using a time-dependent compartment model
Publication Year: 2000 Source: Inflamm Bowel Dis PMID: 11149560 DOI: 10.1002/ibd.3780060405
Lupus specific autoantigens are exposed on apoptotic cells. The increased number of apoptotic lymphocytes reported in systemic lupus erythematosus (SLE) may be attributable to abnormalities of lymphocyte Fas expression or serum soluble Fas. In the present study we analysed the count of circulating apoptotic lymphocytes in SLE patients (n=50), by …
Familial and sporadic inflammatory bowel disease: different entities?
Publication Year: 2000 Source: Inflamm Bowel Dis PMID: 11149564 DOI: 10.1002/ibd.3780060409
BACKGROUND: Protection against vaccine-preventable diseases is important in inflammatory bowel disease (IBD) because of increased susceptibility and severity of infection with immunosuppressive therapy. However, immunosuppressive therapy may affect vaccine response. This study aimed to evaluate immunogenicity and safety of influenza vaccination in children with IBD. METHODS: In this prospective cohort …
Elevated thrombopoietin serum levels in patients with inflammatory bowel disease
Publication Year: 2000 Source: Am J Gastroenterol PMID: 11151880 DOI: 10.1111/j.1572-0241.2000.03364.x
The CD1d molecule has been implicated to play a role in inflammatory bowel diseases (IBD), possibly through its presentation of an intestinal antigen trigger. To understand the role of the CD1d class I-like protein in IBD, we investigated the molecule's expression in diseased intestinal tissue and determined its potential to …
Mother to child transmission of anti-S cerevisiae mannan antibodies (ASCA) in non-IBD families
Publication Year: 2000 Source: Gut PMID: 11186432 DOI: 10.1136/gut.47.6.870a
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Cultures of human colonic epithelial cells isolated from endoscopical biopsies from patients with inflammatory bowel disease. Effect of IFNgamma, TNFalpha and IL-1beta on viability, butyrate oxidation and IL-8 secretion
Publication Year: 2000 Source: Autoimmunity PMID: 11191284 DOI: 10.3109/08916930008994099
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Probiotic therapy fails to improve gut permeability in a hapten model of colitis
Publication Year: 2000 Source: Scand J Gastroenterol PMID: 11199365 DOI: 10.1080/003655200453601
Variance component analysis of quantitative trait loci (QTL) is an important strategy of genetic mapping for complex traits in humans. The method is robust because it can handle an arbitrary number of alleles with arbitrary modes of gene actions. The variance component method is usually implemented using the proportion of …
Disease outcome in inflammatory bowel disease: mortality, morbidity and therapeutic management of a 796-person inception cohort in the European Collaborative Study on Inflammatory Bowel Disease (EC-IBD)
Publication Year: 2000 Source: Scand J Gastroenterol PMID: 11199366 DOI: 10.1080/003655200453610
The management of the patient with inflammatory bowel disease (IBD) is challenging for both the physician and the patient. IBD imposes both a physical and emotional burden on patients' lives. Palliative care is important for IBD patients because it focuses on improving quality of life. While palliative care does not …
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