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Concordance of inflammatory bowel disease among Danish twins. Results of a nationwide study

Publication Year: 2000 Source: Scand J Gastroenterol PMID: 11099061 DOI: 10.1080/003655200451207

Inflammatory bowel disease (IBD) has a definite genetic component as documented by epidemiological and linkage evidence. It shows an earlier onset of disease in children of affected patients than in their parents. This has lead to speculations about genetic anticipation in this disorder. 2,007 IBD patients with sporadic disease and …

Results of multiple diagnostic tests for Mycobacterium avium subsp. paratuberculosis in patients with inflammatory bowel disease and in controls

Publication Year: 2000 Source: J Clin Microbiol PMID: 11101567 DOI: 10.1128/JCM.38.12.4373-4381.2000

Dysplasia in inflammatory bowel disease (IBD) is categorized as either flat or associated with a raised lesion or mass (dysplasia-associated lesion or mass [DALM]). One specific subtype of a dysplasia-associated lesion or mass consists of isolated discrete nodules or polyps that are difficult to distinguish from sporadic adenomas. Because the …

Inflammatory bowel disease

Publication Year: 2000 Source: Indian J Pediatr PMID: 11105426 DOI: 10.1007/BF02723935

Patients with inflammatory bowel diseases (IBD) are at increased risk for thromboembolic complications. Our aim was to evaluate whether the increased risk for thrombosis in IBD could be due to a genetic association of IBD with hereditary prothrombotic conditions. In all, 102 IBD patients (51 with ulcerative colitis and 51 …

Detection of Listeria monocytogenes by polymerase chain reaction in intestinal mucosal biopsies from patients with inflammatory bowel disease and controls

Publication Year: 2000 Source: J Gastroenterol Hepatol PMID: 11106094 DOI: 10.1046/j.1440-1746.2000.02331.x

BACKGROUND: Elective cesarean section (CS) may be recommended for patients with Crohn's disease and perineal involvement. Little is known about CS rates in parous women with inflammatory bowel disease (IBD), nor the possible long-term impact of vaginal delivery and episiotomy on continence in women with IBD. METHODS: Questionnaires were sent …

Noninvasive assessment of cardiac ischemic injury using (87)Rb and (23)Na MR imaging, (31)P MR, and optical spectroscopy

Publication Year: 2000 Source: Magn Reson Med PMID: 11108627 DOI: 10.1002/1522-2594(200012)44:6<899::aid-mrm11>3.0.co;2-7

We hypothesized that the neuroprotection against cerebral hypoxic-ischemic damage observed with dexamethasone treatment in immature rats is related to a change in cerebral protein synthesis. Six-day-old Wistar rats were injected with either vehicle (10 ml/kg) or dexamethasone (0.1 mg/kg) 24 h prior to cerebral hypoxia-ischemia. Local cerebral protein synthesis (incorporation …

6-mercaptopurine or methotrexate added to prednisone induces and maintains remission in steroid-dependent inflammatory bowel disease

Publication Year: 2000 Source: Eur J Gastroenterol Hepatol PMID: 11111780 DOI: 10.1097/00042737-200012110-00010

Hydrogen sulfide (H₂S) is a toxic gas that is now recognized as an important mediator of many physiological processes. In the colon, H₂S is produced both endogenously and by naturally occurring sulfate-reducing bacteria (SRB). The full arrays of its effects in the gastrointestinal tract are still being elucidated, but they …

Wavelet-based enhancement for detection of left ventricular myocardial boundaries in magnetic resonance images

Publication Year: 2000 Source: Magn Reson Imaging PMID: 11118768 DOI: 10.1016/s0730-725x(00)00202-2

Comment in Dis Colon Rectum. 2011 Dec;54(12):1463-4. BACKGROUND: Venous thromboembolism constitutes a major cause of morbidity associated with surgical procedures. Colorectal surgical patients are at an elevated risk for postoperative venous thromboembolism. Whether the laparoscopic approach influences this risk is not well defined. OBJECTIVE: This study aimed to assess the …

3D image registration using a fast noniterative algorithm

Publication Year: 2000 Source: Magn Reson Imaging PMID: 11118769 DOI: 10.1016/s0730-725x(00)00209-5

We present the case of a 37-year-old woman with severe refractory colonic and perianal Crohn's disease who had lost response to second-line, steroid-sparing treatments azathioprine, methotrexate and infliximab. For many such patients extensive surgery has often been considered the only option. New insights provided by the results of genome-wide association …

Treatment with fluoride or bisphosphonates prevents bone loss associated with colitis in the rat

Publication Year: 2000 Source: Calcif Tissue Int PMID: 11136535 DOI: 10.1007/s002230001162

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Cellular immune response to human cartilage glycoprotein-39 (HC gp-39)-derived peptides in rheumatoid arthritis and other inflammatory conditions

Publication Year: 2000 Source: Rheumatology (Oxford) PMID: 11136874 DOI: 10.1093/rheumatology/39.12.1326

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