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Linkage detection adaptive to linkage disequilibrium: the disequilibrium maximum-likelihood-binomial test for affected-sibship data
Publication Year: 1999 Source: Am J Hum Genet PMID: 10577929 DOI: 10.1086/302659
OBJECTIVES: To investigate the relationship of intestinal permeability in children and adolescents with inflammatory bowel disease (IBD) to disease activity, disease extent, and response to therapy. STUDY DESIGN: Patients with new and established diagnoses of IBD (12 Crohn's disease [CD] and 18 ulcerative colitis [UC]) were studied. Intestinal permeability was …
A genome-wide search identifies potential new susceptibility loci for Crohn's disease
Publication Year: 1999 Source: Inflamm Bowel Dis PMID: 10579120 DOI: 10.1097/00054725-199911000-00005
To assess the mechanisms of osteopenia in inflammatory bowel disease (IBD), the serum markers of bone formation (osteocalcin and carboxyterminal propeptide of type I procollagen (PICP)) and bone degradation (carboxyterminal telopeptide of type I collagen (ICTP)), the bone mineral density (BMD) of the lumbar spine and the proximal femur and …
Measurement of pANCA (antineutrophil cytoplasmic antibodies) and ASCA (anti-saccharomyces cerevisiae) in screening for IBD in young children
Publication Year: 1999 Source: Inflamm Bowel Dis PMID: 10579122 DOI: 10.1097/00054725-199911000-00007
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Putative inflammatory and immunological mechanisms in functional bowel disorders
Publication Year: 1999 Source: Baillieres Best Pract Res Clin Gastroenterol PMID: 10580919 DOI: 10.1053/bega.1999.0037
Not found
Enhancing yield of infectious Bursal disease virus structural proteins in baculovirus expression systems: focus on media, protease inhibitors, and dissolved oxygen
Publication Year: 1999 Source: Biotechnol Prog PMID: 10585191 DOI: 10.1021/bp990094k
OBJECTIVES: Several recent reports have suggested that the process of dissociation is independently associated with several distressing conditions such as psychiatric diagnoses, somatization, current psychological distress, and past sexual and physical victimization. These studies, however, have not taken into account possible shared variance between these variables. Is dissociation uniquely related …
Colonoscopy and technetium-99m white cell scan in children with suspected inflammatory bowel disease
Publication Year: 1999 Source: J Pediatr PMID: 10586176 DOI: 10.1016/s0022-3476(99)70092-2
BACKGROUND: Earlier studies have indicated that inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), is associated with thromboembolic complications, whereas inherited disorders of coagulation occur less often than expected in IBD patients. The point mutation Arg506Gln of factor V (Factor V Leiden), resulting in resistance to …
Aminosalicylic acid inhibits IkappaB kinase alpha phosphorylation of IkappaBalpha in mouse intestinal epithelial cells
Publication Year: 1999 Source: J Biol Chem PMID: 10593965 DOI: 10.1074/jbc.274.51.36631
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Design of artificial neural network and its applications to the analysis of alcoholism data
Publication Year: 1999 Source: Genet Epidemiol PMID: 10597440 DOI: 10.1002/gepi.1370170738
In the past years the advances in therapy of IBD have been characterized mainly by the more widespread use of immunosuppression. Especially azathioprine is currently used in Crohn's disease with methotrexate as the second-line immunosuppressive drug. Cyclosporin may become a drug of choice to treat severe ulcerative colitis but its …
Genome search for alcohol dependence using the weighted pairwise correlation linkage method: interesting findings on chromosome 4
Publication Year: 1999 Source: Genet Epidemiol PMID: 10597473 DOI: 10.1002/gepi.1370170771
INTRODUCTION: Inflammatory bowel diseases (IBD) have classically included two entities: Crohn's disease (CD) and ulcerative colitis (UC). The correct differentiation between these two diseases has important implications. The term inflammatory bowel disease unclassified (IBDu) describes inflammatory changes of the colon that cannot be classified as ulcerative colitis or Crohn's disease. …
Search for a gene x environment interaction: G x E hunt
Publication Year: 1999 Source: Genet Epidemiol PMID: 10597481 DOI: 10.1002/gepi.1370170779
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