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Increased mucosal production of granulocyte colony-stimulating factor is related to a delay in neutrophil apoptosis in Inflammatory Bowel disease
Publication Year: 1999 Source: J Gastroenterol Hepatol PMID: 10029277 DOI: 10.1046/j.1440-1746.1999.01807.x
This study was performed in order to assess the cytotoxic activity, both natural (NK) and antibody-dependent (ADCC), of PBMC from 38 IBD patients and correlate it with their clinical features. Cytotoxicity assays were performed using sensitive target cells for NK and ADCC activities. In some experiments, highly purified NK cells, …
Correlation between faecal excretion of indium-111-labelled granulocytes and calprotectin, a granulocyte marker protein, in patients with inflammatory bowel disease
Publication Year: 1999 Source: Scand J Gastroenterol PMID: 10048733 DOI: 10.1080/00365529950172835
Not found
Morphologic criteria applicable to biopsy specimens for effective distinction of inflammatory bowel disease from other forms of colitis and of Crohn's disease from ulcerative colitis
Publication Year: 1999 Source: Scand J Gastroenterol PMID: 10048734 DOI: 10.1080/00365529950172844
BACKGROUND: Pediatric inflammatory bowel disease (IBD) may be phenotypically different from adult IBD. In IBD lesions, macrophages are overactivated, suggesting involvement of innate immunity in the pathogenesis. Here, mucosal macrophages were studied in selected untreated pediatric patients compared with adults from a population-based Norwegian cohort of IBD patients. Age-matched non-IBD …
A genomewide analysis provides evidence for novel linkages in inflammatory bowel disease in a large European cohort
Publication Year: 1999 Source: Am J Hum Genet PMID: 10053016 DOI: 10.1086/302294
Not found
Mouse colitis induced by Escherichia coli producing Yersinia enterocolitica 60-kilodalton heat-shock protein: light and electron microscope study
Publication Year: 1999 Source: Dig Dis Sci PMID: 10063936 DOI: 10.1023/a:1026691525874
We used sib-pair linkage analysis as part of an epidemiologic approach to solving Problem 2 of the GAW10 data set of nuclear families. We recoded the quantitative trait Q1 into a dichotomous trait using Q1 > or = 40 as the cut-point. In a case-control design of sib-pair analysis, the …
Evidence of T cell receptor beta-chain patterns in inflammatory and noninflammatory bowel disease states
Publication Year: 1999 Source: Am J Physiol PMID: 10070037 DOI: 10.1152/ajpgi.1999.276.3.G613
Erratum in Mol Psychiatry 1999 Jan;4(1):100. Comment in Mol Psychiatry. 1998 Sep;3(5):370-2. Attention deficit hyperactivity disorder (ADHD) is a common neurobehavioral problem afflicting 5-10% of children and adolescents and persisting into adulthood in 30-50% or more of cases. Family, twin, and adoption studies suggest genetic factors contribute to ADHD and …
Haemonchus contortus: sequence heterogeneity of internucleotide binding domains from P-glycoproteins
Publication Year: 1999 Source: Exp Parasitol PMID: 10072327 DOI: 10.1006/expr.1998.4373
T cell activation, as defined by expression of relevant cell surface molecules, such as the interleukin-2 receptor (CD25), is increased in many chronic relapsing diseases, including inflammatory bowel disease (IBD). These T cells are generally activated through contact of their clonotypic T cell receptor (TCR) with a peptide antigen presented …
Interleukin (IL)-13 and IL-4 are potent inhibitors of IL-8 secretion by human intestinal epithelial cells
Publication Year: 1999 Source: Dig Dis Sci PMID: 10080164 DOI: 10.1023/a:1026638330843
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Inflammatory bowel disease
Publication Year: 1999 Source: Endoscopy PMID: 10082412 DOI: 10.1055/s-1999-13650
The authors observed a patient with severe inflammatory bowel disease (IBD) complicated by ten episodes of deep venous thrombosis (DVT). Her unusual thrombotic tendency prompted further investigation for primary hypercoagulability. A nonfamilial deficiency of Protein S was documented suggesting the deficiency was acquired. This occurrence suggests that low Protein S …
Therapeutic effects of LK 423, a phthalimido-desmuramyl-dipeptide compound, on dextran sulfate sodium-induced colitis in rodents through restoring their interleukin-10 producing capacity
Publication Year: 1999 Source: Arzneimittelforschung PMID: 10083986 DOI: 10.1055/s-0031-1300400
BACKGROUND: The sphingolipid sphingomyelin is a constituent in food derived from animals. Digestive breakdown of sphingomyelin results in ceramide, recently suggested to be involved in activation of cathepsin D as a novel mediator of apoptosis. Damage of the epithelial barrier was detected in patients with inflammatory bowel disease (IBD) due …
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