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Thromboembolism and resistance to activated protein C in patients with inflammatory bowel disease

Publication Year: 1999 Source: Am J Gastroenterol PMID: 10086652 DOI: 10.1111/j.1572-0241.1999.00937.x

IBD is associated with an increased activation of intestinal immune cells, which causes overproduction of proinflammatory cytokines such as IL-1beta. IL-1beta is implicated in mediating the sustained inflammatory response. IL-1 receptor antagonist (IL-1Ra), the naturally occurring inhibitor of IL-1, has been shown to have beneficial effects in experimental models of …

Survival of home parenteral nutrition-treated patients: 20 years of experience at the Mayo Clinic

Publication Year: 1999 Source: Mayo Clin Proc PMID: 10089988 DOI: 10.4065/74.3.217

Not found

Paramyxovirus infections in childhood and subsequent inflammatory bowel disease

Publication Year: 1999 Source: Gastroenterology PMID: 10092301 DOI: 10.1016/s0016-5085(99)70062-4

Not found

Salivary SIgA and SIgA 1 in coeliac disease, inflammatory bowel disease and controls

Publication Year: 1999 Source: Ir J Med Sci PMID: 10098341 DOI: 10.1007/BF02939578

OBJECTIVE: The differential diagnosis of chronic colitis in inflammatory bowel disease (IBD) is challenging and a distinction between Crohn's disease (CD) and ulcerative colitis (UC) is not always possible. Matrix metalloproteinases (MMPs) cleave components of the extracellular matrix and their dysregulation leads to damage to the mucosa. They are involved …

Arg506Gln factor V mutation and Val34Leu factor XIII polymorphism in Finnish patients with inflammatory bowel disease

Publication Year: 1999 Source: Scand J Gastroenterol PMID: 10192195 DOI: 10.1080/00365529950173032

Comment in Cancer Causes Control. 1998 Aug;9(4):355-6. OBJECTIVES: It has been suggested that inflammatory bowel disease (IBD) and colon cancer are associated because they have genetic susceptibility in common, rather than IBD causing cancer. We examined the risk of colorectal cancer in first-degree relatives of patients with IBD in order …

[Consequences of galenic considerations and clinical results for therapy of ulcerative colitis]

Publication Year: 1999 Source: Med Klin (Munich) PMID: 10194948 DOI: 10.1007/BF03042033

INTRODUCTION: The endovascular repair of bilateral iliac aneurysms using bilateral Iliac Branch Devices (IBDs) has been infrequently performed and reported.We aim to describe this technique and report on the results of our case series. METHODS: Three different device designs are available. The procedural options include a totally transfemoral approach, or …

Multipoint genomic scanning for quantitative loci: effects of map density, sibship size and computational approach

Publication Year: 1999 Source: Eur J Hum Genet PMID: 10196691 DOI: 10.1038/sj.ejhg.5200280

Not found

Testing of human homologues of murine obesity genes as candidate regions in Finnish obese sib pairs

Publication Year: 1999 Source: Eur J Hum Genet PMID: 10196693 DOI: 10.1038/sj.ejhg.5200256

BACKGROUND: A population based epidemiological study identified all the patients diagnosed with ulcerative colitis (UC) or Crohn's disease (CD) resident in the Florence area in the period 1978-1992. AIMS: To assess the mortality of unselected patients with inflammatory bowel disease (IBD) in a Mediterranean country. METHODS: Overall, 920 patients (689 …

Prevention and treatment of osteoporosis in patients with inflammatory bowel disease

Publication Year: 1999 Source: Am J Gastroenterol PMID: 10201450 DOI: 10.1111/j.1572-0241.1999.981_d.x

BACKGROUND: Patients with ulcerative colitis (UC) and concomitant perianal disease (PAD) are occasionally seen, but the impact of PAD on UC outcome has been scarcely assessed. AIMS: To evaluate the prevalence, clinical features and outcomes of PAD among UC patients. METHODS: Patients with an initial diagnosis of UC who ever …

Elevated pancreatic enzymes in inflammatory bowel disease are associated with extensive disease

Publication Year: 1999 Source: Am J Gastroenterol PMID: 10201484 DOI: 10.1111/j.1572-0241.1999.01015.x

BACKGROUND: Several studies have suggested that clinical indices of disease activity in inflammatory bowel disease (IBD) do not adequately reflect the degree of inflammation in most such patients. Faecal excretion of indium-111-labelled neutrophilic granulocytes has been suggested as the gold standard of disease activity, but its complexity and high cost …

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