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Spontaneous inflammatory bowel disease in multiple mutant mouse lines: association with colonization by Helicobacter hepaticus

Publication Year: 1998 Source: Helicobacter PMID: 9631303 DOI: 10.1046/j.1523-5378.1998.08006.x

Not found

Large airway disease associated with inflammatory bowel disease

Publication Year: 1998 Source: Chest PMID: 9631822 DOI: 10.1378/chest.113.6.1723

The prediction of identity by descent (IBD) probabilities is essential for all methods that map quantitative trait loci (QTL). The IBD probabilities may be predicted from marker genotypes and/or pedigree information. Here, a method is presented that predicts IBD probabilities at a given chromosomal location given data on a haplotype …

IL-1beta and TNF-alpha, but not IFN-alpha, IFN-gamma, IL-6 or IL-8, are secretory mediators in human distal colon

Publication Year: 1998 Source: Cytokine PMID: 9632533 DOI: 10.1006/cyto.1997.0307

PURPOSE: In health-related quality of life (HRQOL) studies, data are often collected on multiple domains for two or more groups of study participants. Quantitative measures of relative importance, which are used to rank order the domains based on their ability to discriminate between groups, are an alternative to multiple tests …

Linkage and association between inflammatory bowel disease and a locus on chromosome 12

Publication Year: 1998 Source: Am J Hum Genet PMID: 9634527 DOI: 10.1086/301929

BACKGROUND: Reactive oxygen species contribute to tissue injury in inflammatory bowel disease (IBD). The tripeptide glutathione (GSH) is the most important intracellular antioxidant. AIMS: To investigate constituent amino acid plasma levels and the GSH redox status in different compartments in IBD with emphasis on intestinal GSH synthesis in Crohn's disease. …

Taurine can ameliorate inflammatory bowel disease in rats

Publication Year: 1998 Source: Adv Exp Med Biol PMID: 9635044 DOI: 10.1007/978-1-4899-0117-0_37

Not found

Activated protein C resistance, thrombophilia, and inflammatory bowel disease

Publication Year: 1998 Source: Dig Dis Sci PMID: 9635631 DOI: 10.1023/a:1018840715357

BACKGROUND: The reliability of self-report regarding health care utilization in inflammatory bowel disease (IBD) is unknown. If proven reliable, it could help justify self-report as a means of determining health care utilization and associated costs. METHODS: The Manitoba IBD Cohort Study is a population-based longitudinal study of participants diagnosed within …

Adhesion and cytosolic dye transfer between macrophages and intestinal epithelial cells

Publication Year: 1998 Source: Cell Adhes Commun PMID: 9638330 DOI: 10.3109/15419069809040283

Inflammatory bowel disease (IBD) is characterised by altered immunoregulation and augmented synthesis of nitric oxide. The purpose of this study was to determine the effects of exogenous IL-4, introduced by a recombinant human type 5 adenovirus (Ad5) vector, on the tissue injury associated with an experimental model of colonic immune …

Effects of steroid treatment on activation of nuclear factor kappaB in patients with inflammatory bowel disease

Publication Year: 1998 Source: Br J Pharmacol PMID: 9647464 DOI: 10.1038/sj.bjp.0701887

TNF-alpha is a major cytokine involved in inflammatory bowel disease (IBD). In this study, water extract of Grifola frondosa (GFW) was evaluated for its protective effects against colon inflammation through the modulation of TNF-alpha action. In coculture of HT-29 human colon cancer cells with U937 human monocytic cells, TNF-alpha-induced monocyte …

CD4+ T cells from 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced colitis rodents migrate to the recipient's colon upon transfer; down-regulation by CD8+ T cells

Publication Year: 1998 Source: Clin Exp Immunol PMID: 9649183 DOI: 10.1046/j.1365-2249.1998.00564.x

Contractile responses evoked by the 5-HT IB/D receptor agonists, dihydroergotamine, naratriptan and sumatriptan, were compared in canine isolated coronary artery rings before and after endothelial dysfunction as obtained by inhibition of nitric oxide synthase with Nw-nitro-L-arginine methyl ester (L-NAME; 10 microM). The three agonists contracted rings in the potency order …

Colonic explant production of IL-1and its receptor antagonist is imbalanced in inflammatory bowel disease (IBD)

Publication Year: 1998 Source: Clin Exp Immunol PMID: 9649212 DOI: 10.1046/j.1365-2249.1998.00595.x

Tissue injury and inflammation in inflammatory bowel disease (IBD) are associated with enhanced monocytic lysosomal enzyme release. In this study, peripheral monocytes and lamina propria mononuclear cells (LPMNC) were isolated from IBD patients and normal controls. Cells were stimulated with lipopolysaccharide after treatment with IL-13, IL-4, and IL-10, and enzyme …

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