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An Unusual Case Presentation of Non-Pathergy Induced Severe Pyoderma Gangrenosum Localized to the Perianal and Intragluteal Regions
Publication Year: 2024 Source: S D Med PMID: 38986145
Pyoderma gangrenosum is a rare neutrophil based disorder presenting as a painful sterile ulcer usually below the knee. The disease is also linked to comorbid conditions including inflammatory bowel disease (IBD) and pathergy. Mainstay treatment begins with high dose steroids, either topical for limited disease or systemic for extensive or …
Deep Bayesian active learning-to-rank with relative annotation for estimation of ulcerative colitis severity
Publication Year: 2024 Source: Med Image Anal PMID: 38986351
No Abstract
Performance evaluation of a smartphone-based home test for fecal calprotection
Publication Year: 2024 Source: Clin Chem Lab Med PMID: 38986473 DOI: 10.1515/cclm-2024-0422
OBJECTIVES: Fecal calprotectin (FC) serves as a non-invasive marker for the assessment of gut inflammation in patients with inflammatory bowel disease (IBD). Laboratory measurements are usually performed with immunologic methods like enzyme-linked immunosorbent assay. Recently, quantitative home tests based on the lateral flow technology with smartphones as read-out devices have …
[Frontiers and challenges in diagnosis and treatment for Crohn's disease -from epidemiology to treatment]
Publication Year: 2024 Source: Nihon Shokakibyo Gakkai Zasshi PMID: 38987163
No Abstract
[Monitoring disease activity with biomarkers in Crohn's disease]
Publication Year: 2024 Source: Nihon Shokakibyo Gakkai Zasshi PMID: 38987164 DOI: 10.11405/nisshoshi.121.535
No Abstract
[Medical treatment and approaches for Crohn's disease]
Publication Year: 2024 Source: Nihon Shokakibyo Gakkai Zasshi PMID: 38987165
No Abstract
[Current status and issues of surgical treatment for Crohn's disease]
Publication Year: 2024 Source: Nihon Shokakibyo Gakkai Zasshi PMID: 38987166
No Abstract
[Practice of pediatric Crohn's disease]
Publication Year: 2024 Source: Nihon Shokakibyo Gakkai Zasshi PMID: 38987167 DOI: 10.11405/nisshoshi.121.566
No Abstract
Differences in Clinical Practice and Disease Course Between Elderly-Onset and Long-Standing Elderly Ulcerative Colitis: A Single-Center Study in Japan
Publication Year: 2024 Source: Tohoku J Exp Med PMID: 38987210
No Abstract
Ribonuclease 4 functions as an intestinal antimicrobial protein to maintain gut microbiota and metabolite homeostasis
Publication Year: 2024 Source: Nat Commun PMID: 38987259 DOI: 10.1038/s41467-024-50223-1
Antimicrobial proteins contribute to host-microbiota interactions and are associated with inflammatory bowel disease (IBD), but our understanding on antimicrobial protein diversity and functions remains incomplete. Ribonuclease 4 (Rnase4) is a potential antimicrobial protein with no known function in the intestines. Here we find that RNASE4 is expressed in intestinal epithelial …
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