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The distribution of dividing T cells throughout the intestinal wall in inflammatory bowel disease (IBD)
Publication Year: 1996 Source: Clin Exp Immunol PMID: 8625521 DOI: 10.1046/j.1365-2249.1996.999701.x
Comment in Eur J Gastroenterol Hepatol. 1995 Nov;7(11):1021-3. BACKGROUND: Immunoregulatory properties of cytokines may mediate disordered inflammatory events in inflammatory bowel diseases (IBDs). On the basis of data obtained in experimental colitis, the hypothesis has been advanced that in IBD the balance between interleukin-1 (IL-1) and the naturally occurring IL-1 …
Tolerance towards resident intestinal flora in mice is abrogated in experimental colitis and restored by treatment with interleukin-10 or antibodies to interleukin-12
Publication Year: 1996 Source: Eur J Immunol PMID: 8625991 DOI: 10.1002/eji.1830260432
Erratum in J Immunol. 2009 Sep 15;183(6):4135. Svend, Rietdijk [corrected to Rietdijk, Svend]; Borst, Jannine [corrected to Borst, Jannie]. The pathogenesis of human inflammatory bowel disease (IBD) and most experimental models of IBD is dependent on the activation and expansion of CD4(+) T cells via interaction with mucosal APCs. The …
[Bronchiolitis associated with ulcerative colitis]
Publication Year: 1996 Source: Arch Bronconeumol PMID: 8634796 DOI: 10.1016/s0300-2896(15)30804-8
Addition of 5% freeze-dried IBD virus (IBDV)-immune bovine colostrum to the diet of chickens prevented infection when housed in an IBDV-contaminated environment. Four of five chickens receiving 2.5%, and all chickens receiving 0.5% or no IBDV-immune colostrum were infected. No interference with development of an active immunity was found in …
Current medical therapy for inflammatory bowel disease
Publication Year: 1996 Source: South Med J PMID: 8638193 DOI: 10.1097/00007611-199606000-00002
Not found
Cytokine imbalance and autoantibody production in T cell receptor-alpha mutant mice with inflammatory bowel disease
Publication Year: 1996 Source: J Exp Med PMID: 8642289 DOI: 10.1084/jem.183.3.847
BACKGROUND: Enzyme-treated rice fiber (ERF) is a recently developed prebiotic product made from rice bran by heat-resistant amylase, protease and hemicellulase treatment. Although the detailed mechanism of inflammatory bowel disease (IBD) is still unclear, the role of the resident luminal bacteria and its interaction on the mucosal barrier seem to …
Increased leukocyte adhesiveness/aggregation in patients with inflammatory bowel disease during remission. Further evidence for subclinical inflammation
Publication Year: 1996 Source: Dis Colon Rectum PMID: 8646948 DOI: 10.1007/BF02056941
Comment in Gastrointest Endosc. 1996 May;43(5):524-8. BACKGROUND: Oral sodium phosphate (NaP) is increasingly used as a colonic cleansing agent for colonoscopy. It has been shown to be efficacious, well-tolerated, and safe. Mucosal abnormalities associated with NaP have recently been described. We carried out this controlled study to assess whether bowel …
Polyclonal expansion of adoptively transferred CD4+ alpha beta T cells in the colonic lamina propria of scid mice with colitis
Publication Year: 1996 Source: Eur J Immunol PMID: 8647181 DOI: 10.1002/eji.1830260529
The intestinal ecosystem is balanced by dynamic interactions between resident and incoming microbes, the gastrointestinal barrier, and the mucosal immune system. However, in the context of inflammatory bowel diseases (IBD), where the integrity of the gastrointestinal barrier is compromised, resident microbes contribute to the development and perpetuation of inflammation and …
Detection of exfoliated carcinoma cells in colonic luminal washings by identification of deranged patterns of expression of the CD44 gene
Publication Year: 1996 Source: J Clin Pathol PMID: 8655705 DOI: 10.1136/jcp.49.4.300
Plasma lipoprotein(a) [Lp(a)], a low density lipoprotein particle with an attached apolipoprotein(a) [apo(a)], varies widely in concentration between individuals. These concentration differences are heritable and inversely related to the number of kringle 4 repeats in the apo(a) gene. To define the genetic determinants of plasma Lp(a) levels, plasma Lp(a) concentrations …
Inverse correlation between Helicobacter pylori infection and inflammatory bowel disease
Publication Year: 1996 Source: J Clin Pathol PMID: 8666689 DOI: 10.1136/jcp.49.1.65
Not found
Secretion of tumour necrosis factor alpha and lymphotoxin alpha in relation to polymorphisms in the TNF genes and HLA-DR alleles. Relevance for inflammatory bowel disease
Publication Year: 1996 Source: Scand J Immunol PMID: 8668926 DOI: 10.1046/j.1365-3083.1996.d01-65.x
There is now increasing evidence that hyperresponsiveness towards intestinal flora is a crucial event in the pathogenesis of inflammatory bowel disease (IBD). In support of this hypothesis, we recently described in humans that tolerance exists towards indigenous intestinal flora but is broken in active IBD lesions. In the present study, …
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