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Unlocking the potential of photon counting detector CT for paediatric imaging: a pictorial essay

Publication Year: 2024 Source: BJR Open PMID: 39021509

No Abstract

Enhancing the performance of porous silicon biosensors: the interplay of nanostructure design and microfluidic integration

Publication Year: 2024 Source: Microsyst Nanoeng PMID: 39021530

No Abstract

Crohn's Disease Associated With IgA Nephropathy Effectively Treated With the Interleukin-23 Inhibitor Risankizumab

Publication Year: 2024 Source: ACG Case Rep J PMID: 39021716 DOI: 10.14309/crj.0000000000001437

Extraintestinal manifestations (EIMs) are common in inflammatory bowel disease (IBD). Renal EIMs, including immunoglobulin A nephropathy (IgAN), are relatively rare. EIMs are important to consider when developing a treatment plan for IBD. Studies differ on whether IBD disease activity correlates with IgAN disease activity. Published guidance on effective therapies for …

Unraveling the fatigue puzzle: insights into the pathogenesis and management of IBD-related fatigue including the role of the gut-brain axis

Publication Year: 2024 Source: Front Med (Lausanne) PMID: 39021817 DOI: 10.3389/fmed.2024.1424926

A significant percentage of patients with an inflammatory bowel disease (IBD) encounter fatigue which can profoundly diminish patients' quality of life, particularly during periods of disease remission when gastrointestinal symptoms have receded. Various contributing risk factors have been identified including active inflammation, anemia, psychological, lifestyle and drug-related factors. While addressing …

Dual role of transient receptor potential ankyrin 1 in respiratory and gastrointestinal physiology: From molecular mechanisms to therapeutic targets

Publication Year: 2024 Source: Front Physiol PMID: 39022308

No Abstract

Empiric Treatment of Classical Pyoderma Gangrenosum in the Outpatient Setting: A Case Report

Publication Year: 2024 Source: Cureus PMID: 39022471

No Abstract

Miao sour soup alleviates DSS-induced colitis in mice: modulation of gut microbiota and intestinal barrier function

Publication Year: 2024 Source: Food Funct PMID: 39023128 DOI: 10.1039/d4fo01794c

Miao sour soup (MSS), a daily fermented food in Guizhou, China, is rich in microorganisms with various beneficial activities, including anti-inflammatory and antioxidant activities. However, the therapeutic effects of MSS on IBD remain unexplored. This study aimed to investigate the protective effect of MSS against colitis in mice. In this …

Commensal microbiome and gastrointestinal mucosal immunity: Harmony and conflict with our closest neighbor

Publication Year: 2024 Source: Immun Inflamm Dis PMID: 39023417 DOI: 10.1002/iid3.1316

BACKGROUND: The gastrointestinal tract contains a wide range of microorganisms that have evolved alongside the immune system of the host. The intestinal mucosa maintains balance within the intestines by utilizing the mucosal immune system, which is controlled by the complex gut mucosal immune network. OBJECTIVE: This review aims to comprehensively …

Serological responses to vaccination in children exposed in utero to ustekinumab or vedolizumab: cross-sectional analysis of a prospective multicentre cohort

Publication Year: 2024 Source: Eur J Pediatr PMID: 39023645 DOI: 10.1007/s00431-024-05683-4

Evidence on serological responses to vaccination in children exposed to ustekinumab (UST) or vedolizumab (VDZ) in utero is lacking. This multicentre prospective study aimed to assess the impact of prenatal exposure to UST or VDZ due to maternal inflammatory bowel disease (IBD) on serological responses to vaccination and other immunological …

Primary caregiver burden and undiagnosed mental health illness in out-patients with inflammatory bowel disease-A multicentric prospective survey from the IBD Emerging Nations' Consortium

Publication Year: 2024 Source: Indian J Gastroenterol PMID: 39023742 DOI: 10.1007/s12664-024-01617-y

BACKGROUND: Mental health is an overlooked aspect of inflammatory bowel disease (IBD) patient care with limited data from the developing world. The primary caregiver burden is expected to be high, but has not been evaluated. METHODS: We conducted a questionnaire-based survey of consecutive out-patients with no diagnosed mental health illness …

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