|
IcsP (SopA)
|
icsP/sopA
|
0.0084112 |
2,528 |
VF0122
|
Exoenzyme |
(icsP/sopA) outer membrane protease of the OmpP family, involved in cleavage of surface exposed IcsA [IcsP (SopA) (VF0122) - Exoenzyme (VFC0251)] [Shigella flexneri 2a str. 301]
|
|
FBPs
|
fbaA
|
0.0000067 |
1 |
VF0243
|
Adherence |
(sfbII/sof) serum opacification factor [FBPs (VF0243) - Adherence (VFC0001)] [Streptococcus pyogenes MGAS6180]
|
|
Ata
|
ata
|
0.0000033 |
1 |
VF1333
|
Adherence |
(ata) trimeric autotransporter adhesin Ata [Ata (VF1333) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU]
|
|
TFP
|
pilG
|
0.0002162 |
36 |
VF1334
|
Adherence |
(pilS) PAS domain-containing sensor histidine kinase [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU]
|
|
IcsA (VirG)
|
icsA/virG
|
0.0000067 |
2 |
VF0121
|
Motility |
(icsA/virG) autotransporter, actin tail assembly protein IcsA/VirG [IcsA (VirG) (VF0121) - Motility (VFC0204)] [Shigella flexneri 2a str. 301]
|
|
LPS
|
gtrA
|
3.2350476 |
283,051 |
VF0124
|
Immune modulation |
(gtrA) bactoprenol-linked glucose translocase/flippase [LPS (VF0124) - Immune modulation (VFC0258)] [Shigella flexneri 2a str. 301]
|
|
Capsule
|
cap8G
|
0.0079755 |
2,363 |
VF0003
|
Immune modulation |
(cap8O) type 8 capsular polysaccharide synthesis protein Cap8O [Capsule (VF0003) - Immune modulation (VFC0258)] [Staphylococcus aureus subsp. aureus MW2]
|
|
CbetaG
|
cgs
|
0.0000033 |
1 |
VF0366
|
Immune modulation |
(cgs) cyclic beta 1-2 glucan synthetase [CbetaG (VF0366) - Immune modulation (VFC0258)] [Brucella melitensis bv. 1 str. 16M]
|
|
Aerobactin
|
iutA
|
0.0299364 |
7,067 |
VF0123
|
Nutritional/Metabolic factor |
(iucC) aerobactin synthesis protein IucC [Aerobactin (VF0123) - Nutritional/Metabolic factor (VFC0272)] [Shigella flexneri 2a str. 301]
|
|
Type I pili
|
fimD
|
0.0000399 |
10 |
VF0486
|
Adherence |
(fimC) outer membrane usher protein [Type I pili (VF0486) - Adherence (VFC0001)] [Aeromonas hydrophila ML09-119]
|
|
Hyaluronic acid capsule
|
hasB
|
0.0000166 |
5 |
VF0244
|
Immune modulation |
(hasB) UDP-glucose 6-dehydrogenase HasB [Hyaluronic acid capsule (VF0244) - Immune modulation (VFC0258)] [Streptococcus pyogenes M1 GAS]
|
|
VirB type IV secretion system
|
virB3
|
0.0000133 |
1 |
VF0365
|
Effector delivery system |
(virB3) type IV secretion system protein VirB3 [VirB type IV secretion system (VF0365) - Effector delivery system (VFC0086)] [Brucella melitensis bv. 1 str. 16M]
|
|
T6SS
|
vgrG/tssI
|
0.00002 |
5 |
VF1337
|
Effector delivery system |
(tssC) type VI secretion system contractile sheath large subunit [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU]
|
|
Streptokinase
|
ska
|
0.0000033 |
1 |
VF0247
|
Exoenzyme |
(ska) streptokinase A precursor [Streptokinase (VF0247) - Exoenzyme (VFC0251)] [Streptococcus pyogenes M1 GAS]
|
|
BvrR-BvrS
|
bvrR
|
0.0000133 |
3 |
VF0368
|
Regulation |
(bvrR) response regulator transcription factor [BvrR-BvrS (VF0368) - Regulation (VFC0301)] [Brucella melitensis bv. 1 str. 16M]
|
|
TCP
|
tcpA
|
0.0000033 |
1 |
VF0126
|
Adherence |
(tcpA) toxin-coregulated pilus (TCP) major pilin TcpA [TCP (VF0126) - Adherence (VFC0001)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
LPS
|
wzt
|
1.000276 |
300,622 |
VF0367
|
Immune modulation |
(gmd) GDP-mannose 4,6-dehydratase [LPS (VF0367) - Immune modulation (VFC0258)] [Brucella melitensis bv. 1 str. 16M]
|
|
Hyaluronidase
|
hylA
|
0.0000033 |
1 |
VF0246
|
Exoenzyme |
(hylA) hyaluronidase [Hyaluronidase (VF0246) - Exoenzyme (VFC0251)] [Streptococcus pyogenes M1 GAS]
|
|
T2SS
|
gspE2
|
0.0000565 |
15 |
VF1335
|
Effector delivery system |
(gspC) general secretion pathway protein C [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU]
|
|
VirB/VirD4 type IV secretion system
|
virB10
|
0.00001 |
3 |
VF0369
|
Effector delivery system |
(virB10) type IV secretion system virB10 protein homolog [VirB/VirD4 type IV secretion system (VF0369) - Effector delivery system (VFC0086)] [Bartonella henselae str. Houston-1]
|
|
ACF
|
acfD
|
0.0000033 |
1 |
VF0127
|
Others |
(acfD) accessory colonization factor AcfD [ACF (VF0127) - Others (VFC0346)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
BmaA
|
bmaA
|
0.0000266 |
8 |
VF1339
|
Adherence |
(bmaA) autotransporter outer membrane beta-barrel domain-containing protein [BmaA (VF1339) - Adherence (VFC0001)] [Brucella suis 1330]
|
|
Sulfolipid-1 biosynthesis and transport
|
stf0
|
0.0000067 |
1 |
VF0803
|
Immune modulation |
(pks2) phthioceranic/hydroxyphthioceranic acid synthase [Sulfolipid-1 biosynthesis and transport (VF0803) - Immune modulation (VFC0258)] [Mycobacterium tuberculosis H37Rv]
|
|
T6SS
|
AHA_RS09305
|
0.1360424 |
17,603 |
VF0480
|
Effector delivery system |
(hcp1) HcpA-like protein [T6SS (VF0480) - Effector delivery system (VFC0086)] [Aeromonas hydrophila subsp. hydrophila ATCC 7966]
|
|
Pic
|
pic
|
0.000276 |
83 |
VF0120
|
Exoenzyme |
(pic) serine protease, autotransporter Pic [Pic (VF0120) - Exoenzyme (VFC0251)] [Shigella flexneri 2a str. 301]
|
|
TraJ
|
AAA92657
|
0.2296397 |
68,859 |
VF0241
|
Invasion |
(AAA92657) unknown protein [TraJ (VF0241) - Invasion (VFC0083)] [Escherichia coli]
|
|
BopD
|
bopD
|
0.0000366 |
11 |
VF0362
|
Biofilm |
(bopD) sugar-binding transcriptional regulator, LacI family [BopD (VF0362) - Biofilm (VFC0271)] [Enterococcus faecalis V583]
|
|
CNF-1
|
cnf1
|
0.0000366 |
11 |
VF0240
|
Exotoxin |
(cnf1) cytotoxic necrotizing factor 1 [CNF-1 (VF0240) - Exotoxin (VFC0235)] [Escherichia coli str. E-B35]
|
|
Capsule
|
cpsB/cdsA
|
0.0000499 |
15 |
VF0361
|
Immune modulation |
(cpsB/cdsA) phosphatidate cytidylyltransferase [Capsule (VF0361) - Immune modulation (VFC0258)] [Enterococcus faecalis V583]
|
|
RtxA
|
rtxE
|
0.0000067 |
2 |
VF0482
|
Exotoxin |
(rtxD) RTX toxin transporter, transmembrane protein linking with the outer membrane porin TolC [RtxA (VF0482) - Exotoxin (VFC0235)] [Aeromonas hydrophila subsp. hydrophila ATCC 7966]
|
|
Pic
|
pic
|
0.0003392 |
95 |
VF0232
|
Effector delivery system |
(pic) Pic serine protease precursor, autotransporter [Pic (VF0232) - Effector delivery system (VFC0086)] [Escherichia coli CFT073]
|
|
PhoPQ
|
phoP
|
2.0026773 |
300,654 |
VF0111
|
Regulation |
(phoP) response regulator in two-component regulatory system with PhoQ [PhoPQ (VF0111) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Lateral flagella
|
lafC
|
0.0000266 |
8 |
VF0474
|
Motility |
(lfgG) lateral flagellar basal-body rod protein LfgG [Lateral flagella (VF0474) - Motility (VFC0204)] [Aeromonas salmonicida subsp. salmonicida A449]
|
|
Polar flagella
|
nueA
|
2.0006485 |
300,665 |
VF0473
|
Motility |
(flrA) FleQ protein [Polar flagella (VF0473) - Motility (VFC0204)] [Aeromonas hydrophila ML09-119]
|
|
GroEL
|
groEL
|
0.0004556 |
110 |
VF0594
|
Adherence |
(groEL) chaperonin GroEL [GroEL (VF0594) - Adherence (VFC0001)] [Clostridium difficile 630]
|
|
Sat
|
sat
|
0.0000166 |
4 |
VF0231
|
Effector delivery system |
(sat) Aecreted auto transpoter toxin [Sat (VF0231) - Effector delivery system (VFC0086)] [Escherichia coli CFT073]
|
|
AS
|
EF0485
|
0.0000033 |
1 |
VF0352
|
Adherence |
(EF0485) aggregation substance [AS (VF0352) - Adherence (VFC0001)] [Enterococcus faecalis V583]
|
|
Fur
|
fur
|
1.0002428 |
300,649 |
VF0113
|
Regulation |
(fur) ferric iron uptake transcriptional regulator [Fur (VF0113) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Chu
|
chuX
|
0.0119433 |
1,985 |
VF0234
|
Nutritional/Metabolic factor |
(chuY) ChuY [Chu (VF0234) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli O157:H7 str. EDL933]
|
|
Ace
|
ace
|
0.0000033 |
1 |
VF0355
|
Adherence |
(ace) collagen adhesin protein [Ace (VF0355) - Adherence (VFC0001)] [Enterococcus faecalis V583]
|
|
Flp type IV pili
|
flpF
|
0.0000033 |
1 |
VF0476
|
Adherence |
(flpF) traffic ATPase [Flp type IV pili (VF0476) - Adherence (VFC0001)] [Aeromonas hydrophila ML09-119]
|
|
RpoS
|
rpoS
|
1.009991 |
300,464 |
VF0112
|
Regulation |
(rpoS) RNA polymerase sigma factor RpoS [RpoS (VF0112) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Tsh
|
tsh
|
0.0000399 |
10 |
VF0233
|
Effector delivery system |
(tsh) temperature-sensitive protein Tsh [Tsh (VF0233) - Effector delivery system (VFC0086)] [Escherichia coli O25b:H4-ST131]
|
|
Tap type IV pili
|
tapT
|
0.0000798 |
22 |
VF0475
|
Adherence |
(tapB) type IV pilus assembly ATPase, PilB-like [Tap type IV pili (VF0475) - Adherence (VFC0001)] [Aeromonas hydrophila ML09-119]
|
|
OmpA
|
ompA
|
1.0005454 |
300,648 |
VF0236
|
Invasion |
(ompA) outer membrane protein A [OmpA (VF0236) - Invasion (VFC0083)] [Escherichia coli O18:K1:H7 str. RS218]
|
|
Exe T2SS
|
exeG
|
0.0000565 |
7 |
VF0478
|
Effector delivery system |
(exeD) general secretion pathway protein D [Exe T2SS (VF0478) - Effector delivery system (VFC0086)] [Aeromonas hydrophila ML09-119]
|
|
CDT
|
cdtA
|
0.0000266 |
6 |
VF0115
|
Exotoxin |
(cdtB) cytolethal distending toxin B [CDT (VF0115) - Exotoxin (VFC0235)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
|
|
Flagella
|
motB
|
0.0004623 |
26 |
VF0114
|
Motility |
(motB) flagellar motor protein MotB [Flagella (VF0114) - Motility (VFC0204)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
|
|
AslA
|
aslA
|
0.0072571 |
2,174 |
VF0238
|
Invasion |
(aslA) putative arylsulfatase [AslA (VF0238) - Invasion (VFC0083)] [Escherichia coli O18:K1:H7 str. RS218]
|
|
Shiga toxin
|
stxA
|
0.00001 |
2 |
VF0117
|
Exotoxin |
(stxB) Shiga toxin subunit B precursor [Shiga toxin (VF0117) - Exotoxin (VFC0235)] [Shigella dysenteriae Sd197]
|
|
Hyaluronidase
|
EF3023
|
0.00001 |
1 |
VF0359
|
Exoenzyme |
(EF3023) polysaccharide lyase, family 8 [Hyaluronidase (VF0359) - Exoenzyme (VFC0251)] [Enterococcus faecalis V583]
|
|
Ibes
|
ibeC
|
1.1037646 |
300,653 |
VF0237
|
Invasion |
(ibeB) Cu(+)/Ag(+) efflux RND transporter outer membrane channel CusC [Ibes (VF0237) - Invasion (VFC0083)] [Escherichia coli O45:K1:H7 str. S88]
|
|
TTSS (SPI-1 encode)
|
invB
|
32.0273754 |
300,617 |
VF0116
|
Effector delivery system |
(sipC/sspC) type III secretion system hydrophilic translocator, pore protein SipC [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
T3SS
|
ascN
|
0.0000166 |
5 |
VF0479
|
Effector delivery system |
(ascU) Type III secretion system inner membrane export apparatus protein AscU [T3SS (VF0479) - Effector delivery system (VFC0086)] [Aeromonas salmonicida subsp. salmonicida A449]
|
|
SigA
|
sigA
|
0.0000299 |
8 |
VF0119
|
Exoenzyme |
(sigA) serine protease, autotransporter SigA [SigA (VF0119) - Exoenzyme (VFC0251)] [Shigella flexneri 2a str. 301]
|
|
TTSS
|
spa15
|
0.0001264 |
5 |
VF0118
|
Effector delivery system |
(ipgE) type III secretion system chaperone for IpgD [TTSS (VF0118) - Effector delivery system (VFC0086)] [Shigella flexneri 2a str. 301]
|
|
K1 capsule
|
neuA
|
0.0098546 |
993 |
VF0239
|
Invasion |
(kpsC) Capsule polysaccharide export protein [K1 capsule (VF0239) - Invasion (VFC0083)] [Escherichia coli O45:K1:H7 str. S88]
|
|
HSI-2 T6SS secreted effectors
|
vgrG2b
|
0.0000033 |
1 |
VF0915
|
Effector delivery system |
(vgrG2b) Type VI secretion system spike protein VgrG2b; metallopeptidase effector VgrG2b [HSI-2 T6SS secreted effectors (VF0915) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
Phospholipase C
|
plc1
|
0.00002 |
6 |
VF0470
|
Exotoxin |
(plc2) phospholipase C [Phospholipase C (VF0470) - Exotoxin (VFC0235)] [Acinetobacter baumannii ACICU]
|
|
Salmochelin siderophore
|
iroN
|
3.0109888 |
299,988 |
VF0230
|
Nutritional/Metabolic factor |
(iroB) glucosyltransferase IroB [Salmochelin siderophore (VF0230) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073]
|
|
PNAG
|
pgaC
|
0.00001 |
3 |
VF0472
|
Biofilm |
(pgaC) poly-beta-1,6 N-acetyl-D-glucosamine synthase [PNAG (VF0472) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU]
|
|
BSH
|
bsh
|
0.0000166 |
5 |
VF0350
|
Stress survival |
(bsh) bile salt hydrolase [BSH (VF0350) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
|
|
Capsule
|
cps4D
|
0.0002295 |
65 |
VF0144
|
Immune modulation |
(cps4I) capsular polysaccharide biosynthesis protein Cps4I [Capsule (VF0144) - Immune modulation (VFC0258)] [Streptococcus pneumoniae TIGR4]
|
|
PmrAB
|
pmrA
|
2.0007517 |
300,563 |
VF1355
|
Regulation |
(pmrB) sensory kinase PmrB [PmrAB (VF1355) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
MARTX
|
rtxB
|
0.0000166 |
4 |
VF0265
|
Exotoxin |
(rtxA) RTX toxin RtxA [MARTX (VF0265) - Exotoxin (VFC0235)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
Hpt
|
hpt
|
0.0000067 |
2 |
VF0264
|
Nutritional/Metabolic factor |
(hpt) hexose phosphate transport protein [Hpt (VF0264) - Nutritional/Metabolic factor (VFC0272)] [Listeria monocytogenes EGD-e]
|
|
Autolysin
|
lytA
|
0.0000033 |
1 |
VF0143
|
Exoenzyme |
(lytA) autolysin (N-acetylmuramoyl-L-alanine amidase) [Autolysin (VF0143) - Exoenzyme (VFC0251)] [Streptococcus pneumoniae TIGR4]
|
|
TTSS secreted effectors
|
espR1
|
0.0040742 |
1,215 |
VF1111
|
Effector delivery system |
(espV) type III secretion system effector [TTSS secreted effectors (VF1111) - Effector delivery system (VFC0086)] [Escherichia coli E110019]
|
|
Hyaluronidase
|
hysA
|
0.00001 |
2 |
VF0146
|
Exoenzyme |
(hysA) hyaluronidase [Hyaluronidase (VF0146) - Exoenzyme (VFC0251)] [Streptococcus pneumoniae TIGR4]
|
|
Vat
|
vat
|
0.003715 |
1,069 |
VF1112
|
Effector delivery system |
(vat) vacuolating autotransporter toxin [Vat (VF1112) - Effector delivery system (VFC0086)] [Escherichia coli CFT073]
|
|
Aureolysin
|
aur
|
0.0000033 |
1 |
VF0024
|
Exoenzyme |
(aur) zinc metalloproteinase aureolysin [Aureolysin (VF0024) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus MW2]
|
|
HitABC
|
hitC
|
0.0000067 |
2 |
VF0268
|
Nutritional/Metabolic factor |
(hitC) iron(III) ABC transporter, ATP-binding protein [HitABC (VF0268) - Nutritional/Metabolic factor (VFC0272)] [Haemophilus influenzae Rd KW20]
|
|
IgA1 protease
|
iga
|
0.0000033 |
1 |
VF0147
|
Immune modulation |
(iga) G5 domain-containing protein [IgA1 protease (VF0147) - Immune modulation (VFC0258)] [Streptococcus pneumoniae TIGR4]
|
|
Cya
|
cyaB
|
0.0000333 |
10 |
VF0028
|
Exotoxin |
(cyaB) cyclolysin secretion ATP-binding protein [Cya (VF0028) - Exotoxin (VFC0235)] [Bordetella pertussis Tohama I]
|
|
HSI-3
|
tssH
|
0.8282674 |
248,903 |
VF0944
|
Effector delivery system |
(tssI) type VI secretion system tip protein VgrG [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
HSI-2
|
vgrG
|
0.0000466 |
11 |
VF0943
|
Effector delivery system |
(tssF) type VI secretion system baseplate subunit TssF [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
TTSS effectors secreted via both systems
|
slrP
|
3.5390144 |
300,624 |
VF0948
|
Effector delivery system |
(spvC) type III secretion system effector SpvC, phosphothreonine lyase [TTSS effectors secreted via both systems (VF0948) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
TTSS-2 secreted effectors
|
sseK1
|
13.0669968 |
300,655 |
VF0947
|
Effector delivery system |
(sopD2) type III secretion system effector SopD2 [TTSS-2 secreted effectors (VF0947) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
TTSS-1 secreted effectors
|
sopB/sigD
|
7.5091778 |
300,657 |
VF0949
|
Effector delivery system |
(sopD) type III secretion system effector SopD [TTSS-1 secreted effectors (VF0949) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
CsrA
|
csrA
|
1.000133 |
300,634 |
VF0261
|
Regulation |
(csrA) carbon storage regulator CsrA [CsrA (VF0261) - Regulation (VFC0301)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
TTSS
|
yscU
|
0.0000233 |
7 |
VF0140
|
Effector delivery system |
(yscU) type III secretion system export apparatus switch protein YscU [TTSS (VF0140) - Effector delivery system (VFC0086)] [Yersinia pestis CO92]
|
|
TTSS secreted effectors
|
cif
|
0.0887648 |
26,582 |
VF1110
|
Effector delivery system |
(espX4) Type III secretion system effector EspX4 [TTSS secreted effectors (VF1110) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933]
|
|
RelA
|
relA
|
0.0000266 |
6 |
VF0260
|
Regulation |
(relA) GTP diphosphokinase [RelA (VF0260) - Regulation (VFC0301)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
SvpA
|
hbp2
|
0.0000033 |
1 |
VF0263
|
Nutritional/Metabolic factor |
(hbp2) hypothetical protein [SvpA (VF0263) - Nutritional/Metabolic factor (VFC0272)] [Listeria monocytogenes EGD-e]
|
|
LetA/S
|
letA
|
0.0004091 |
123 |
VF0262
|
Regulation |
(letA) UvrY/SirA/GacA family response regulator transcription factor [LetA/S (VF0262) - Regulation (VFC0301)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
HSI-3 T6SS secreted effectors
|
pldB/tle5b
|
0.0000067 |
2 |
VF1350
|
Effector delivery system |
(pldB/tle5b) phospholipase D [HSI-3 T6SS secreted effectors (VF1350) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
Capsule
|
capB
|
0.00001 |
3 |
VF0141
|
Immune modulation |
(capB) CapB, involved in Poly-gamma-glutamate synthesis [Capsule (VF0141) - Immune modulation (VFC0258)] [Bacillus anthracis]
|
|
SE
|
sell
|
0.0000033 |
1 |
VF0020
|
Exotoxin |
(sell) staphylococcal enterotoxin L precursor [SE (VF0020) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Isocitrate lyase
|
icl
|
1.0002095 |
300,592 |
VF0253
|
Others |
(icl) Isocitrate lyase Icl (isocitrase) (isocitratase) [Isocitrate lyase (VF0253) - Others (VFC0346)] [Mycobacterium tuberculosis H37Rv]
|
|
Ail
|
ail
|
0.0000067 |
2 |
VF0132
|
Invasion |
(ail) attachment invasion locus protein [Ail (VF0132) - Invasion (VFC0083)] [Yersinia pestis CO92]
|
|
Gamma-hemolysin
|
hlgC
|
0.0000067 |
2 |
VF0011
|
Exotoxin |
(hlgC) gamma-hemolysin component C [Gamma-hemolysin (VF0011) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus MW2]
|
|
TcdB
|
toxB
|
0.0000067 |
2 |
VF0377
|
Exotoxin |
(toxB) toxin B [TcdB (VF0377) - Exotoxin (VFC0235)] [Clostridium difficile 630]
|
|
Shu
|
shuT
|
0.0000998 |
21 |
VF0256
|
Nutritional/Metabolic factor |
(shuT) periplasmic binding protein ShuT [Shu (VF0256) - Nutritional/Metabolic factor (VFC0272)] [Shigella dysenteriae Sd197]
|
|
Intercellular adhesion proteins
|
icaB
|
0.0000067 |
1 |
VF0014
|
Biofilm |
(icaB) N-deacetylase, involved in polysaccharide intercellular adhesin(PIA) synthesis [Intercellular adhesion proteins (VF0014) - Biofilm (VFC0271)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Myf/pH6 antigen
|
psaB
|
0.0001264 |
38 |
VF0134
|
Adherence |
(psaC) outer membrane usher protein PsaC [Myf/pH6 antigen (VF0134) - Adherence (VFC0001)] [Yersinia pestis CO92]
|
|
TcdA
|
toxA
|
0.0000033 |
1 |
VF0376
|
Exotoxin |
(toxA) toxin A [TcdA (VF0376) - Exotoxin (VFC0235)] [Clostridium difficile 630]
|
|
ShET2
|
senB
|
0.0002927 |
87 |
VF0258
|
Exotoxin |
(senB) enterotoxin [ShET2 (VF0258) - Exotoxin (VFC0235)] [Shigella boydii Sb227]
|
|
Eap/Map
|
eap/map
|
0.0000033 |
1 |
VF0016
|
Adherence |
(eap/map) extracellular adherence protein Eap/Map [Eap/Map (VF0016) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
|
|
SigA
|
sigA/rpoV
|
0.0002328 |
58 |
VF0257
|
Regulation |
(sigA/rpoV) RNA polymerase sigma factor SigA [SigA (VF0257) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
Yersiniabactin
|
fyuA/psn
|
0.408636 |
13,578 |
VF0136
|
Nutritional/Metabolic factor |
(irp1) yersiniabactin biosynthetic protein Irp1 [Yersiniabactin (VF0136) - Nutritional/Metabolic factor (VFC0272)] [Yersinia pestis CO92]
|
|
Isd
|
isdG
|
0.0000033 |
1 |
VF0015
|
Nutritional/Metabolic factor |
(isdG) iron-regulated surface determinant protein G [Isd (VF0015) - Nutritional/Metabolic factor (VFC0272)] [Staphylococcus aureus subsp. aureus str. Newman]
|
|
Pla
|
pla
|
1.0262879 |
300,235 |
VF0139
|
Exoenzyme |
(pla) plasminogen activator protease precursor [Pla (VF0139) - Exoenzyme (VFC0251)] [Yersinia pestis CO92]
|
|
F1 antigen
|
caf1A
|
0.0000565 |
13 |
VF0138
|
Immune modulation |
(caf1A) F1 capsule anchoring protein [F1 antigen (VF0138) - Immune modulation (VFC0258)] [Yersinia pestis CO92]
|
|
SpA
|
spa
|
0.0000033 |
1 |
VF0017
|
Exotoxin |
(spa) Immunoglobulin G binding protein A precursor [SpA (VF0017) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus MW2]
|
|
RtxA
|
rtxA
|
0.0000033 |
1 |
VF0259
|
Exotoxin |
(rtxA) structural toxin protein RtxA [RtxA (VF0259) - Exotoxin (VFC0235)] [Legionella pneumophila str. Paris]
|
|
SDr
|
sdrC
|
0.0000067 |
2 |
VF0019
|
Adherence |
(sdrC) Ser-Asp rich fibrinogen-binding bone sialoprotein-binding protein [SDr (VF0019) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Pld
|
pld
|
0.0000033 |
1 |
VF0491
|
Exotoxin |
(pld) phospholipase D [Pld (VF0491) - Exotoxin (VFC0235)] [Rickettsia typhi str. Wilmington]
|
|
FnBPs
|
fnbA
|
0.00001 |
2 |
VF0010
|
Adherence |
(fnbA) fibronectin-binding protein A [FnBPs (VF0010) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Flagella
|
flgC
|
0.0000033 |
1 |
VF0373
|
Motility |
(flgC) flagellar basal-body rod protein FlgC [Flagella (VF0373) - Motility (VFC0204)] [Bartonella bacilliformis KC583]
|
|
Trw type IV secretion system
|
korA
|
0.0010709 |
30 |
VF0372
|
Effector delivery system |
(trwG) Trw type IV secretion sysmtem VirB8 homolog, trwG protein [Trw type IV secretion system (VF0372) - Effector delivery system (VFC0086)] [Bartonella henselae str. Houston-1]
|
|
Ent
|
entS
|
1.0249708 |
300,565 |
VF0562
|
Nutritional/Metabolic factor |
(entD) enterochelin synthetase component D [Ent (VF0562) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
OatA
|
oatA
|
0.00001 |
3 |
VF0441
|
Immune modulation |
(oatA) peptidoglycan O-acetyltransferase [OatA (VF0441) - Immune modulation (VFC0258)] [Listeria monocytogenes EGD-e]
|
|
LPS
|
KP1_RS17225
|
1.0997536 |
160,226 |
VF0561
|
Immune modulation |
(KP1_RS17230) glycosyltransferase [LPS (VF0561) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
LntA
|
lntA
|
0.0000033 |
1 |
VF0440
|
Immune modulation |
(lntA) listeria nuclear targeted protein A [LntA (VF0440) - Immune modulation (VFC0258)] [Listeria monocytogenes EGD-e]
|
|
Ybt
|
ybtS
|
0.0913623 |
13,538 |
VF0564
|
Nutritional/Metabolic factor |
(ybtE) yersiniabactin biosynthesis salycil-AMP ligase YbtE [Ybt (VF0564) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
CadF
|
cadF
|
0.0000033 |
1 |
VF0322
|
Adherence |
(cadF) outer membrane fibronectin-binding protein [CadF (VF0322) - Adherence (VFC0001)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
|
|
Sal
|
iroN
|
2.086603 |
300,009 |
VF0563
|
Nutritional/Metabolic factor |
(iroD) siderophore esterase IroD [Sal (VF0563) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
TTSS (SPI-2 encode)
|
ssaX
|
31.0406325 |
300,653 |
VF0321
|
Effector delivery system |
(ssaO) type III secretion system stalk protein SsaO [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
PgdA
|
pdgA
|
0.0000033 |
1 |
VF0442
|
Immune modulation |
(pdgA) Peptidoglycan N-deacetylase [PgdA (VF0442) - Immune modulation (VFC0258)] [Listeria monocytogenes EGD-e]
|
|
Type I fimbriae
|
fimI
|
0.534285 |
159,272 |
VF0566
|
Adherence |
(fimG) type 1 fimbrial minor component [Type I fimbriae (VF0566) - Adherence (VFC0001)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
InlJ
|
inlJ
|
0.0000067 |
2 |
VF0445
|
Adherence |
(inlJ) internalin J [InlJ (VF0445) - Adherence (VFC0001)] [Listeria monocytogenes EGD-e]
|
|
Lap
|
lap
|
0.0011707 |
339 |
VF0444
|
Adherence |
(lap) Listeria adhesion protein Lap [Lap (VF0444) - Adherence (VFC0001)] [Listeria monocytogenes EGD-e]
|
|
Capsule
|
glf
|
0.0012239 |
348 |
VF0323
|
Immune modulation |
(gmhA2) phosphoheptose isomerase [Capsule (VF0323) - Immune modulation (VFC0258)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
|
|
Aerobactin
|
iutA
|
0.073326 |
8,891 |
VF0565
|
Nutritional/Metabolic factor |
(iucC) aerobactin siderophore biosynthesis protein IucC [Aerobactin (VF0565) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Intimin
|
eae
|
0.0000166 |
5 |
VF0202
|
Effector delivery system |
(eae) intimin type gamma [Intimin (VF0202) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933]
|
|
AcrAB
|
acrA
|
5.0478729 |
300,669 |
VF0568
|
Antimicrobial activity/Competitive advantage |
(acrB) acriflavine resistance protein B [AcrAB (VF0568) - Antimicrobial activity/Competitive advantage (VFC0325)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
LOS
|
gmhB
|
0.0000166 |
5 |
VF0326
|
Immune modulation |
(gmhB) D-glycero-alpha-D-manno-heptose-1,7-bisphosphate 7-phosphatase [LOS (VF0326) - Immune modulation (VFC0258)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
|
|
Type 3 fimbriae
|
mrkI
|
0.0172647 |
889 |
VF0567
|
Biofilm |
(mrkC) fimbrial biogenesis outer membrane usher protein mrkC precursor [Type 3 fimbriae (VF0567) - Biofilm (VFC0271)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
LapB
|
lapB
|
0.0000133 |
4 |
VF0446
|
Adherence |
(lapB) Listeria adhesion protein LapB [LapB (VF0446) - Adherence (VFC0001)] [Listeria monocytogenes EGD-e]
|
|
Hemolysin
|
hlyA
|
0.0000399 |
4 |
VF0207
|
Exotoxin |
(hlyA) Hemolysin A [Hemolysin (VF0207) - Exotoxin (VFC0235)] [Escherichia coli O157:H7 str. EDL933]
|
|
MOMP
|
porA
|
0.00002 |
6 |
VF0328
|
Adherence |
(porA) major outer membrane protein [MOMP (VF0328) - Adherence (VFC0001)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
|
|
T6SS
|
vipA/tssB
|
0.0704424 |
3,115 |
VF0569
|
Effector delivery system |
(vgrG/tssI) type VI secretion system tip protein VgrG [T6SS (VF0569) - Effector delivery system (VFC0086)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Stx
|
stx2B
|
0.0000565 |
7 |
VF0206
|
Exotoxin |
(stx2B) shiga-like toxin II B subunit encoded by bacteriophage BP-933W [Stx (VF0206) - Exotoxin (VFC0235)] [Escherichia coli O157:H7 str. EDL933]
|
|
StcE
|
stcE
|
0.0000166 |
5 |
VF0209
|
Exoenzyme |
(stcE) metalloprotease [StcE (VF0209) - Exoenzyme (VFC0251)] [Escherichia coli O157:H7 str. EDL933]
|
|
EspP
|
espP
|
0.000133 |
35 |
VF0208
|
Effector delivery system |
(espP) autotransporter, serine protease [EspP (VF0208) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933]
|
|
Capsule
|
wcaJ
|
10.4392176 |
300,657 |
VF0560
|
Immune modulation |
(KP1_RS17305) GDP-L-fucose synthase [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Flagella
|
motB
|
0.0004457 |
111 |
VF0430
|
Motility |
(tsr) methyl-accepting chemotaxis protein I [Flagella (VF0430) - Motility (VFC0204)] [Burkholderia pseudomallei K96243]
|
|
FupA
|
feoB
|
0.0000532 |
14 |
VF0550
|
Nutritional/Metabolic factor |
(feoB) Fe(2+) transporter permease subunit FeoB [FupA (VF0550) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
GGT
|
ggt
|
0.0001264 |
33 |
VF0553
|
Nutritional/Metabolic factor |
(ggt) gamma-glutamyltranspeptidase [GGT (VF0553) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
Antigen 85
|
fbpD
|
0.0000033 |
1 |
VF0311
|
Adherence |
(fbpD) MPT51/MPB51 antigen [Antigen 85 (VF0311) - Adherence (VFC0001)] [Mycobacterium tuberculosis H37Rv]
|
|
CdpA
|
cdpA
|
0.0000033 |
1 |
VF0432
|
Regulation |
(cdpA) cyclic di-GMP phosphodiesterase [CdpA (VF0432) - Regulation (VFC0301)] [Burkholderia pseudomallei K96243]
|
|
Biotin synthesis
|
bioB
|
0.00001 |
3 |
VF0552
|
Nutritional/Metabolic factor |
(bioB) biotin synthase [Biotin synthesis (VF0552) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
Quorum-sensing
|
pmlR/bspR1
|
0.0000798 |
24 |
VF0433
|
Biofilm |
(pmlR/bspR1) N-acylhomoserine lactone dependent regulatory protein [Quorum-sensing (VF0433) - Biofilm (VFC0271)] [Burkholderia pseudomallei K96243]
|
|
Capsule I
|
manC
|
0.0046263 |
1,259 |
VF0436
|
Immune modulation |
(wcbP) capsular polysaccharide biosynthesis dehydrogenase/reductase [Capsule I (VF0436) - Immune modulation (VFC0258)] [Burkholderia pseudomallei K96243]
|
|
ESX-1
|
espG1
|
0.0000033 |
1 |
VF0315
|
Effector delivery system |
(espG1) ESX-1 secretion-associated protein EspG1 [ESX-1 (VF0315) - Effector delivery system (VFC0086)] [Mycobacterium tuberculosis H37Rv]
|
|
MmaA4
|
mmaA4
|
0.0000033 |
1 |
VF0314
|
Others |
(mmaA4) hydroxymycolate synthase MmaA4 [MmaA4 (VF0314) - Others (VFC0346)] [Mycobacterium tuberculosis H37Rv]
|
|
Dot/Icm T4SS secreted effectors
|
LPG_RS00040
|
0.0001131 |
31 |
VF0798
|
Effector delivery system |
(LPG_RS13310) Dot/Icm type IV secretion system effector [Dot/Icm T4SS secreted effectors (VF0798) - Effector delivery system (VFC0086)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
BoaB
|
boaB
|
0.0000333 |
9 |
VF0435
|
Adherence |
(boaB) autotransporter protein [BoaB (VF0435) - Adherence (VFC0001)] [Burkholderia pseudomallei K96243]
|
|
Purine biosynthesis
|
purCD
|
0.0000033 |
1 |
VF0559
|
Nutritional/Metabolic factor |
(purCD) fusion protein PurC/PurD [Purine biosynthesis (VF0559) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
EtpA
|
etpB
|
0.0147005 |
3,068 |
VF0437
|
Adherence |
(etpA) Two-partner secreted adhesin EtpA [EtpA (VF0437) - Adherence (VFC0001)] [Escherichia coli O78:H11:K80 str. H10407]
|
|
Pyrimidine biosynthesis
|
carB
|
0.0043935 |
1,128 |
VF0558
|
Nutritional/Metabolic factor |
(carB) carbamoyl phosphate synthase large subunit [Pyrimidine biosynthesis (VF0558) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
PanC/PanD
|
panC
|
0.0000299 |
9 |
VF0319
|
Nutritional/Metabolic factor |
(panC) pantothenate synthetase [PanC/PanD (VF0319) - Nutritional/Metabolic factor (VFC0272)] [Mycobacterium tuberculosis H37Rv]
|
|
LAM
|
aftD
|
0.0000067 |
2 |
VF0318
|
Immune modulation |
(aftD) alpha-(1->3)-arabinofuranosyltransferase [LAM (VF0318) - Immune modulation (VFC0258)] [Mycobacterium tuberculosis H37Rv]
|
|
Type 1 fimbriae
|
fimI
|
0.001653 |
343 |
VF0221
|
Adherence |
(fimF) FimF protein precursor [Type 1 fimbriae (VF0221) - Adherence (VFC0001)] [Escherichia coli CFT073]
|
|
BfmRS
|
bfmS
|
0.0003093 |
89 |
VF0463
|
Regulation |
(bfmS) signal transduction histidine kinase [BfmRS (VF0463) - Regulation (VFC0301)] [Acinetobacter baumannii ACICU]
|
|
Pyocyanin
|
phzH
|
0.0000532 |
3 |
VF0100
|
Nutritional/Metabolic factor |
(phzC1) phenazine biosynthesis protein PhzC [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1]
|
|
P fimbriae
|
papC
|
0.0255894 |
2,838 |
VF0220
|
Adherence |
(papA) P pilus major subunit PapA [P fimbriae (VF0220) - Adherence (VFC0001)] [Escherichia coli CFT073]
|
|
Bap
|
bap
|
0.0000233 |
7 |
VF0462
|
Biofilm |
(bap) biofilm-associated protein [Bap (VF0462) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU]
|
|
Capsule
|
galE
|
0.0021286 |
617 |
VF0465
|
Immune modulation |
(ACICU_RS00500) phosphomannomutase/phosphoglucomutase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU]
|
|
Type 1 fimbriae
|
fimI
|
9.0235074 |
300,654 |
VF0102
|
Adherence |
(fimW) helix-turn-helix transcriptional regulator [Type 1 fimbriae (VF0102) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Dr adhesins
|
draB
|
0.0020221 |
605 |
VF0223
|
Adherence |
(draP) DraP [Dr adhesins (VF0223) - Adherence (VFC0001)] [Escherichia coli O75:K5:H- str. IH11128]
|
|
Bacillibactin
|
dhbF
|
0.0000333 |
8 |
VF0586
|
Nutritional/Metabolic factor |
(dhbE) 2,3-dihydroxybenzoate adenylase DhbE [Bacillibactin (VF0586) - Nutritional/Metabolic factor (VFC0272)] [Bacillus cereus ATCC 10987]
|
|
Vi antigen
|
tviE
|
0.2654496 |
7,980 |
VF0101
|
Immune modulation |
(vexA) Vi polysaccharide export protein VexA [Vi antigen (VF0101) - Immune modulation (VFC0258)] [Salmonella enterica subsp. enterica serovar Typhi str. CT18]
|
|
S fimbriae
|
sfaC
|
0.0007117 |
213 |
VF0222
|
Adherence |
(sfaC) S fimbrial switch regulatory protein SfaC [S fimbriae (VF0222) - Adherence (VFC0001)] [Escherichia coli UTI89]
|
|
OmpA
|
ompA
|
0.0000133 |
3 |
VF0464
|
Immune modulation |
(ompA) outer membrane protein OmpA [OmpA (VF0464) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU]
|
|
Acinetobactin
|
barB
|
0.0014035 |
408 |
VF0467
|
Nutritional/Metabolic factor |
(basG) acinetobactin biosynthesis protein BasF [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU]
|
|
Pef
|
pefA
|
0.9221674 |
70,382 |
VF0104
|
Adherence |
(pefB) plasmid-encoded fimbriae regulatory protein PefB [Pef (VF0104) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Alpha-Hemolysin
|
hlyA
|
0.0003525 |
42 |
VF0225
|
Exotoxin |
(hlyC) Hemolysin C [Alpha-Hemolysin (VF0225) - Exotoxin (VFC0235)] [Escherichia coli CFT073]
|
|
LpeA
|
lpeA
|
0.0000067 |
2 |
VF0346
|
Invasion |
(lpeA) lipoprotein promoting cell invasion [LpeA (VF0346) - Invasion (VFC0083)] [Listeria monocytogenes EGD-e]
|
|
Agf
|
csgE
|
6.9967905 |
300,650 |
VF0103
|
Adherence |
(csgC) curli assembly protein CsgC [Agf (VF0103) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
F1C fimbriae
|
C_RS05810
|
0.000745 |
24 |
VF0224
|
Adherence |
(focD) F1C fimbrial usher [F1C fimbriae (VF0224) - Adherence (VFC0001)] [Escherichia coli CFT073]
|
|
LPS
|
lpxD
|
0.0000831 |
23 |
VF0466
|
Immune modulation |
(lpxA) acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU]
|
|
Chu
|
chuX
|
0.0080986 |
2,008 |
VF0227
|
Nutritional/Metabolic factor |
(chuT) periplasmic heme-binding protein ChuT [Chu (VF0227) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073]
|
|
Phospholipase D
|
plcD
|
0.00001 |
3 |
VF0469
|
Exotoxin |
(plcD) phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase [Phospholipase D (VF0469) - Exotoxin (VFC0235)] [Acinetobacter baumannii ACICU]
|
|
MgtB
|
mgtB
|
1.0026108 |
299,970 |
VF0106
|
Nutritional/Metabolic factor |
(mgtB) Mg2+ transport protein [MgtB (VF0106) - Nutritional/Metabolic factor (VFC0272)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Auto
|
aut
|
0.0000033 |
1 |
VF0348
|
Invasion |
(aut) autolysin [Auto (VF0348) - Invasion (VFC0083)] [Listeria monocytogenes EGD-e]
|
|
Lpf
|
lpfD
|
3.6554573 |
215,673 |
VF0105
|
Adherence |
(lpfE) long polar fimbrial minor subunit LpfE, adhesin [Lpf (VF0105) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
CNF-1
|
cnf1
|
0.0000299 |
9 |
VF0226
|
Exotoxin |
(cnf1) cytotoxic necrotizing factor 1 [CNF-1 (VF0226) - Exotoxin (VFC0235)] [Escherichia coli UTI89]
|
|
PbpG
|
pbpG
|
0.0000067 |
2 |
VF0468
|
Immune modulation |
(pbpG) D-alanyl-D-alanine endopeptidase PBP7/8 [PbpG (VF0468) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU]
|
|
Rck
|
rck
|
0.2264635 |
67,890 |
VF0108
|
Invasion |
(rck) resistance to complement killing [Rck (VF0108) - Invasion (VFC0083)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Aerobactin
|
iutA
|
0.0704092 |
7,080 |
VF0229
|
Nutritional/Metabolic factor |
(iutA) ferric aerobactin receptor precusor IutA [Aerobactin (VF0229) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073]
|
|
Enterobactin
|
entS
|
12.0468452 |
300,655 |
VF0228
|
Nutritional/Metabolic factor |
(entE) 2,3-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073]
|
|
SodCI
|
sodCI
|
0.4288575 |
128,518 |
VF0109
|
Stress survival |
(sodCI) Gifsy-2 prophage: superoxide dismutase precursor (Cu-Zn) [SodCI (VF0109) - Stress survival (VFC0282)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Exolysin
|
exlA
|
0.0000033 |
1 |
VF0582
|
Effector delivery system |
(exlA) hemolysin [Exolysin (VF0582) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PA7]
|
|
Csu fimbriae
|
csuD
|
0.0000033 |
1 |
VF0461
|
Biofilm |
(csuD) Csu pilus usher protein CsuD [Csu fimbriae (VF0461) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU]
|
|
EF-Tu
|
tufA
|
3.471705 |
300,044 |
VF0460
|
Adherence |
(tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
Colibactin
|
clbG
|
0.0003592 |
20 |
VF0573
|
Exotoxin |
(clbC) colibactin polyketide synthase ClbC [Colibactin (VF0573) - Exotoxin (VFC0235)] [Klebsiella pneumoniae subsp. pneumoniae 1084]
|
|
Heat-labile toxin (LT)
|
eltB
|
0.0000266 |
4 |
VF0210
|
Exotoxin |
(eltB) enterotoxin subunit B (from human) [Heat-labile toxin (LT) (VF0210) - Exotoxin (VFC0235)] [Escherichia coli O78:H11:K80 str. H10407]
|
|
Allantion utilization
|
allR
|
5.1351311 |
257,201 |
VF0572
|
Nutritional/Metabolic factor |
(allA) ureidoglycolate hydrolase [Allantion utilization (VF0572) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
MtrCDE
|
mtrE
|
0.0000133 |
3 |
VF0451
|
Antimicrobial activity/Competitive advantage |
(mtrD) multiple transferable resistance system protein MtrD [MtrCDE (VF0451) - Antimicrobial activity/Competitive advantage (VFC0325)] [Neisseria meningitidis MC58]
|
|
KatA
|
katA
|
0.0011175 |
310 |
VF0454
|
Stress survival |
(katA) catalase [KatA (VF0454) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
|
|
Invasin C/Ilp
|
invC/ilp
|
0.0001064 |
32 |
VF0575
|
Invasion |
(invC/ilp) intimin-like invasin C protein [Invasin C/Ilp (VF0575) - Invasion (VFC0083)] [Yersinia pseudotuberculosis IP 31758]
|
|
T2SS
|
gspD
|
0.000296 |
21 |
VF0333
|
Effector delivery system |
(gspI) general secretion pathway protein I [T2SS (VF0333) - Effector delivery system (VFC0086)] [Shigella dysenteriae Sd197]
|
|
T4SS secreted effectors
|
CBU_0270
|
0.9999933 |
300,607 |
VF0696
|
Effector delivery system |
(CBU_0270) Coxiella Dot/Icm type IVB secretion system translocated effector, trans-2-enoyl-CoA reductase [T4SS secreted effectors (VF0696) - Effector delivery system (VFC0086)] [Coxiella burnetii RSA 493]
|
|
T4SS secreted effectors
|
ricA
|
0.00002 |
6 |
VF0695
|
Effector delivery system |
(ricA) type IV secretion system effector RicA, Rab2 interacting conserved protein A [T4SS secreted effectors (VF0695) - Effector delivery system (VFC0086)] [Brucella melitensis bv. 1 str. 16M]
|
|
Heat-stable toxin (ST)
|
estIa
|
0.0000033 |
1 |
VF0211
|
Exotoxin |
(estIa) heat stable enterotoxin I [Heat-stable toxin (ST) (VF0211) - Exotoxin (VFC0235)] [Escherichia coli O78:H11:K80 str. H10407]
|
|
AAFs
|
aafC
|
0.0006685 |
194 |
VF0214
|
Adherence |
(aafC) aggregative adherence fimbria II usher protein AafC [AAFs (VF0214) - Adherence (VFC0001)] [Escherichia coli O44:H18 042]
|
|
VAS T6SS
|
hcp-1
|
0.000153 |
46 |
VF0335
|
Effector delivery system |
(icmF/vasK) type VI secretion system inner membrane protein VasK [VAS T6SS (VF0335) - Effector delivery system (VFC0086)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
MsrAB
|
msrA/B(pilB
|
0.0001131 |
34 |
VF0456
|
Stress survival |
(msrA/B(pilB)) trifunctional thioredoxin/methionine sulfoxide reductase A/B protein [MsrAB (VF0456) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
|
|
Invasin D
|
invD
|
0.0000965 |
29 |
VF0576
|
Invasion |
(invD) invasin D protein [Invasin D (VF0576) - Invasion (VFC0083)] [Yersinia pseudotuberculosis IP 31758]
|
|
HSI-1
|
icmF1/tssM1
|
0.0001863 |
27 |
VF0334
|
Effector delivery system |
(icmF1/tssM1) type VI secretion system protein IcmF1 [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
MntABC
|
mntB
|
0.00002 |
5 |
VF0455
|
Stress survival |
(mntB) Manganese transport system membrane protein MntB [MntABC (VF0455) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
|
|
Adhesive fimbriae
|
cfaD/cfaE
|
0.0000499 |
10 |
VF0213
|
Adherence |
(cfaC) colonisation factor antigen c, usher [Adhesive fimbriae (VF0213) - Adherence (VFC0001)] [Escherichia coli E24377A]
|
|
T6SS
|
hcp1/tssD1
|
1.1106425 |
89,661 |
VF0579
|
Effector delivery system |
(tssG) Type VI secretion system protein TssG [T6SS (VF0579) - Effector delivery system (VFC0086)] [Shigella sonnei Ss046]
|
|
Pht
|
phtA
|
0.0000033 |
1 |
VF0337
|
Nutritional/Metabolic factor |
(phtA) major facilitator family transporter, phagosomal transporter [Pht (VF0337) - Nutritional/Metabolic factor (VFC0272)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Dispersin
|
aatA
|
0.0000266 |
4 |
VF0215
|
Others |
(aatA) outer membrane protein AatA [Dispersin (VF0215) - Others (VFC0346)] [Escherichia coli O44:H18 042]
|
|
RecN
|
recN
|
0.0000499 |
14 |
VF0457
|
Stress survival |
(recN) DNA repair protein RecN [RecN (VF0457) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
|
|
BvgAS
|
bvgS
|
0.0000033 |
1 |
VF0336
|
Regulation |
(bvgS) virulence factors two-component system sensor histidine kinase BvgS [BvgAS (VF0336) - Regulation (VFC0301)] [Bordetella pertussis Tohama I]
|
|
Pic
|
pic
|
0.0001031 |
31 |
VF0218
|
Effector delivery system |
(pic) Pic serine protease precursor, autotransporter [Pic (VF0218) - Effector delivery system (VFC0086)] [Escherichia coli O44:H18 042]
|
|
Pet
|
pet
|
0.0000698 |
19 |
VF0217
|
Effector delivery system |
(pet) Pet serine protease precursor, autotransporter [Pet (VF0217) - Effector delivery system (VFC0086)] [Escherichia coli O44:H18 042]
|
|
RcsAB
|
rcsB
|
2.0020421 |
300,656 |
VF0571
|
Regulation |
(rcsA) transcriptional activator for ctr capsule biosynthesis [RcsAB (VF0571) - Regulation (VFC0301)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
FarAB
|
farB
|
0.002817 |
800 |
VF0450
|
Antimicrobial activity/Competitive advantage |
(farA) fatty acid efflux system protein FarA [FarAB (VF0450) - Antimicrobial activity/Competitive advantage (VFC0325)] [Neisseria meningitidis MC58]
|
|
RmpA
|
rmpA
|
0.00001 |
3 |
VF0570
|
Regulation |
(rmpA) regulator of mucoid phenotype RmpA [RmpA (VF0570) - Regulation (VFC0301)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Rhamnolipid
|
rhlB
|
0.0000033 |
1 |
VF0089
|
Immune modulation |
(rhlB) rhamnosyltransferase chain B [Rhamnolipid (VF0089) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1]
|
|
Type IV pili
|
pilS
|
0.0013536 |
383 |
VF0401
|
Adherence |
(pilR) type IV pilus biosynthesis protein PilR [Type IV pili (VF0401) - Adherence (VFC0001)] [Yersinia pseudotuberculosis IP 31758]
|
|
SinH
|
sinH
|
1.0305084 |
294,504 |
VF0400
|
Adherence |
(sinH) intimin-like protein [SinH (VF0400) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Type VII secretion system
|
esaA
|
0.0000299 |
4 |
VF0403
|
Effector delivery system |
(essB) type VII secretion system protein EssB, monotopic membrane protein [Type VII secretion system (VF0403) - Effector delivery system (VFC0086)] [Staphylococcus aureus subsp. aureus MW2]
|
|
ECP
|
ykgK/ecpR
|
0.0001297 |
22 |
VF0404
|
Adherence |
(ykgK/ecpR) regulator protein EcpR [ECP (VF0404) - Adherence (VFC0001)] [Escherichia coli O157:H7 str. EDL933]
|
|
Typhoid toxin
|
cdtB
|
0.8311643 |
66,307 |
VF0407
|
Exotoxin |
(pltC) an orphan pertussis-like toxin delivery subunit [Typhoid toxin (VF0407) - Exotoxin (VFC0235)] [Salmonella enterica subsp. enterica serovar Typhi str. CT18]
|
|
AI-2
|
luxS
|
1.000143 |
300,636 |
VF0406
|
Biofilm |
(luxS) S-ribosylhomocysteinase [AI-2 (VF0406) - Biofilm (VFC0271)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
T3SS2
|
vscJ2
|
0.0000033 |
1 |
VF0409
|
Effector delivery system |
(vscJ2) type III secretion system protein VscJ2 [T3SS2 (VF0409) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633]
|
|
T3SS1
|
vscL
|
0.0000399 |
10 |
VF0408
|
Effector delivery system |
(vscG) Type III secretion system chaperone VscG [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633]
|
|
Porin
|
porB
|
0.0000033 |
1 |
VF0081
|
Invasion |
(porB) major outer membrane protein PIB [Porin (VF0081) - Invasion (VFC0083)] [Neisseria meningitidis MC58]
|
|
TTSS
|
pscT
|
0.00001 |
2 |
VF0083
|
Effector delivery system |
(exsA) type III secretion system regulatory protein ExsA [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
Type IV pili
|
vfr
|
1.0007783 |
300,558 |
VF0082
|
Adherence |
(pilY1) type 4 fimbrial biogenesis protein PilY1 [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1]
|
|
LPS
|
wbpL
|
0.0084212 |
2,390 |
VF0085
|
Immune modulation |
(wbpM) nucleotide sugar epimerase/dehydratase WbpM [LPS (VF0085) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1]
|
|
Xcp secretion system
|
xcpQ
|
0.0000067 |
2 |
VF0084
|
Effector delivery system |
(xcpR) general secretion pathway protein E [Xcp secretion system (VF0084) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
LasB
|
lasB
|
0.0000033 |
1 |
VF0087
|
Effector delivery system |
(lasB) elastase LasB [LasB (VF0087) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
ExoA
|
toxA
|
0.0000033 |
1 |
VF0086
|
Exotoxin |
(toxA) exotoxin A precursor [ExoA (VF0086) - Exotoxin (VFC0235)] [Pseudomonas aeruginosa PAO1]
|
|
LOS
|
lgtA
|
0.0000067 |
2 |
VF0078
|
Immune modulation |
(lgtF) glycosyltransferase family 2 protein [LOS (VF0078) - Immune modulation (VFC0258)] [Neisseria meningitidis MC58]
|
|
SSLs
|
set20
|
0.0000033 |
1 |
VF0990
|
Exotoxin |
(set20) superantigen-like protein SSL5 [SSLs (VF0990) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Capsule
|
siaB/synB
|
0.0000067 |
1 |
VF0079
|
Immune modulation |
(siaB/synB) polysialic acid capsule biosynthesis protein SiaB [Capsule (VF0079) - Immune modulation (VFC0258)] [Neisseria meningitidis MC58]
|
|
T3SS1 secreted effectors
|
VPA0450
|
0.0000067 |
2 |
VF0632
|
Effector delivery system |
(vopQ) type III secretion system effector VopQ [T3SS1 secreted effectors (VF0632) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633]
|
|
IlpA
|
IlpA
|
1.0003725 |
300,642 |
VF0513
|
Adherence |
(IlpA) immunogenic lipoprotein A [IlpA (VF0513) - Adherence (VFC0001)] [Vibrio vulnificus YJ016]
|
|
VAS T6SS secreted effectors
|
vgrG-3
|
0.0000033 |
1 |
VF0634
|
Effector delivery system |
(vgrG-3) type VI secretion system effector VgrG-3 protein, lysozyme-like activity, VgrG-3 and TsaB are a toxin-antitoxin complex [VAS T6SS secreted effectors (VF0634) - Effector delivery system (VFC0086)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
MSHA pili
|
mshE
|
0.00002 |
4 |
VF0515
|
Adherence |
(mshL) MSHA biogenesis protein MshL [MSHA pili (VF0515) - Adherence (VFC0001)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
HemO cluster
|
ACICU_RS04590
|
0.0000067 |
2 |
VF0636
|
Nutritional/Metabolic factor |
(ACICU_RS04590) porin family protein [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU]
|
|
OmpU
|
ompU
|
0.0000067 |
2 |
VF0514
|
Adherence |
(ompU) outer membrane protein OmpU [OmpU (VF0514) - Adherence (VFC0001)] [Vibrio vulnificus CMCP6]
|
|
FlpA
|
Cj1279c
|
0.0000067 |
2 |
VF0637
|
Adherence |
(Cj1279c) fibronectin domain-containing lipoprotein [FlpA (VF0637) - Adherence (VFC0001)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
|
|
Flagella
|
cheB
|
0.0001397 |
28 |
VF0519
|
Motility |
(flaA) flagellin [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
TTSS
|
escD
|
0.0856684 |
22,768 |
VF0191
|
Effector delivery system |
(escN) ATPase EscN [TTSS (VF0191) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933]
|
|
InlB
|
inlB
|
0.0000033 |
1 |
VF0070
|
Invasion |
(inlB) Internalin B [InlB (VF0070) - Invasion (VFC0083)] [Listeria monocytogenes EGD-e]
|
|
Per
|
bfpV
|
0.0000399 |
10 |
VF0190
|
Regulation |
(bfpW) BfpW [Per (VF0190) - Regulation (VFC0301)] [Escherichia coli B171]
|
|
ClpC
|
clpC
|
0.0003991 |
102 |
VF0072
|
Stress survival |
(clpC) endopeptidase Clp ATP-binding chain C [ClpC (VF0072) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
|
|
Ami
|
ami
|
0.00001 |
3 |
VF0071
|
Adherence |
(ami) autolysin amidase, adhesin [Ami (VF0071) - Adherence (VFC0001)] [Listeria monocytogenes EGD-e]
|
|
ClpP
|
clpP
|
1.0024545 |
300,647 |
VF0074
|
Stress survival |
(clpP) ATP-dependent Clp protease proteolytic subunit [ClpP (VF0074) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
|
|
Paa
|
paa
|
0.0034589 |
1,019 |
VF0194
|
Adherence |
(paa) outer membrane adhesin Paa [Paa (VF0194) - Adherence (VFC0001)] [Escherichia coli O157:H7 str. EDL933]
|
|
ClpE
|
clpE
|
0.00001 |
3 |
VF0073
|
Stress survival |
(clpE) ATP-dependent protease [ClpE (VF0073) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
|
|
Opa
|
opa
|
0.0000067 |
2 |
VF0076
|
Invasion |
(opa) outer membrane beta-barrel protein [Opa (VF0076) - Invasion (VFC0083)] [Neisseria meningitidis MC58]
|
|
Type IV pili
|
pilG
|
0.0002095 |
60 |
VF0075
|
Adherence |
(pilG) pilus assembly protein PilG [Type IV pili (VF0075) - Adherence (VFC0001)] [Neisseria meningitidis MC58]
|
|
LPS
|
wbtL
|
1.1364648 |
300,644 |
VF0542
|
Immune modulation |
(wbtE) nucleotide sugar dehydrogenase [LPS (VF0542) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
Staphylocoagulase
|
coa
|
0.0000033 |
1 |
VF0421
|
Exoenzyme |
(coa) staphylocoagulase precursor [Staphylocoagulase (VF0421) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus MW2]
|
|
IdeR
|
ideR
|
0.0000033 |
1 |
VF0300
|
Regulation |
(ideR) Iron-dependent repressor and activator IdeR [IdeR (VF0300) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
Nitrate reductase
|
narH
|
0.0040044 |
862 |
VF0302
|
Nutritional/Metabolic factor |
(narG) nitrate reductase subunit alpha [Nitrate reductase (VF0302) - Nutritional/Metabolic factor (VFC0272)] [Mycobacterium tuberculosis H37Rv]
|
|
Capsule
|
galE
|
1.0004324 |
300,648 |
VF0543
|
Immune modulation |
(galE) UDP-glucose 4-epimerase GalE [Capsule (VF0543) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
AdsA
|
adsA
|
0.0000067 |
2 |
VF0422
|
Immune modulation |
(adsA) Adenosine synthase A [AdsA (VF0422) - Immune modulation (VFC0258)] [Staphylococcus aureus subsp. aureus MW2]
|
|
SodA
|
sodA
|
0.0000033 |
1 |
VF0304
|
Stress survival |
(sodA) superoxide dismutase [SodA (VF0304) - Stress survival (VFC0282)] [Mycobacterium tuberculosis H37Rv]
|
|
KatG
|
katG
|
0.0001098 |
28 |
VF0303
|
Stress survival |
(katG) catalase-peroxidase [KatG (VF0303) - Stress survival (VFC0282)] [Mycobacterium tuberculosis H37Rv]
|
|
P97/P102 paralog family
|
p102
|
0.0000698 |
2 |
VF0426
|
Adherence |
(MHP_RS03455) P102 paralog, surface adhesin [P97/P102 paralog family (VF0426) - Adherence (VFC0001)] [Mycoplasma hyopneumoniae 232]
|
|
T6SS-1
|
BPS_RS26875
|
0.0000067 |
2 |
VF0429
|
Effector delivery system |
(BPS_RS26875) response regulator VirG [T6SS-1 (VF0429) - Effector delivery system (VFC0086)] [Burkholderia pseudomallei K96243]
|
|
Bsa T3SS
|
bopC
|
0.0000233 |
7 |
VF0428
|
Effector delivery system |
(bsaQ) Type III secretion system protein BsaQ [Bsa T3SS (VF0428) - Effector delivery system (VFC0086)] [Burkholderia pseudomallei K96243]
|
|
PDIM
|
pks15
|
0.0000133 |
3 |
VF0309
|
Immune modulation |
(pks15) polyketide synthase [PDIM (VF0309) - Immune modulation (VFC0258)] [Mycobacterium tuberculosis H37Rv]
|
|
HSI-1 T6SS secreted effectors
|
tse6
|
0.0000133 |
2 |
VF1194
|
Effector delivery system |
(tse6) NAD(P)(+) glycohydrolase toxin Tse6 [HSI-1 T6SS secreted effectors (VF1194) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
Fap
|
fapD
|
0.0000067 |
2 |
VF1191
|
Adherence |
(fapD) periplasmic accessory protein FapD [Fap (VF1191) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1]
|
|
SCI T6SS secreted effectors
|
tae4
|
2.1752979 |
265,496 |
VF1195
|
Effector delivery system |
(tae4) type VI secretion system effector tae4, L,D-endopeptidase [SCI T6SS secreted effectors (VF1195) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
HBL
|
hblD
|
0.0000033 |
1 |
VF0532
|
Exotoxin |
(hblD) Hemolysin BL lytic component L1 [HBL (VF0532) - Exotoxin (VFC0235)] [Bacillus cereus ATCC 14579]
|
|
TcpC
|
tcpC
|
0.0315328 |
9,270 |
VF0413
|
Immune modulation |
(tcpC) Tir domain containing protein TcpC [TcpC (VF0413) - Immune modulation (VFC0258)] [Escherichia coli CFT073]
|
|
RTX protein
|
frpA
|
0.0000133 |
2 |
VF0897
|
Adherence |
(frpA) iron-regulated protein FrpA [RTX protein (VF0897) - Adherence (VFC0001)] [Neisseria meningitidis MC58]
|
|
InhA
|
BAS_RS06430
|
0.00001 |
3 |
VF0536
|
Exoenzyme |
(inhA) immune inhibitor A metalloprotease [InhA (VF0536) - Exoenzyme (VFC0251)] [Bacillus anthracis str. Sterne]
|
|
Ebp pili
|
srtC
|
0.0000033 |
1 |
VF0538
|
Adherence |
(srtC) sortase [Ebp pili (VF0538) - Adherence (VFC0001)] [Enterococcus faecalis V583]
|
|
Alkaline protease
|
aprA
|
0.00002 |
6 |
VF0090
|
Exoenzyme |
(aprA) alkaline metalloproteinase precursor [Alkaline protease (VF0090) - Exoenzyme (VFC0251)] [Pseudomonas aeruginosa PAO1]
|
|
Alginate
|
algI
|
1.0028669 |
300,631 |
VF0091
|
Biofilm |
(algL) poly(beta-d-mannuronate) lyase precursor AlgL [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1]
|
|
Pyoverdine
|
pvdD
|
0.0001064 |
18 |
VF0094
|
Nutritional/Metabolic factor |
(pvdD) pyoverdine synthetase D [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1]
|
|
Quorum sensing
|
rhlI
|
0.0004091 |
121 |
VF0093
|
Biofilm |
(rhlI) autoinducer synthesis protein RhlL [Quorum sensing (VF0093) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1]
|
|
Pyochelin
|
PA4218
|
0.00002 |
5 |
VF0095
|
Nutritional/Metabolic factor |
(pchD) pyochelin biosynthesis protein PchD [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1]
|
|
RelA
|
relA
|
0.0000299 |
8 |
VF0287
|
Regulation |
(relA) Probable GTP pyrophosphokinase RelA (ATP:GTP 3'-pyrophosphotransferase) (PPGPP synthetase I) ((P)PPGPP synthetase) (GTP diphosphokinase) [RelA (VF0287) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
LOS
|
rffG
|
13.3268988 |
300,659 |
VF0044
|
Immune modulation |
(msbA) lipid transporter ATP-binding/permease [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20]
|
|
PhoP
|
phoP
|
0.00001 |
3 |
VF0286
|
Regulation |
(phoR) Possible two component system response sensor kinase membrane associated PhoR [PhoP (VF0286) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
KatAB
|
katA
|
0.0015499 |
423 |
VF0168
|
Stress survival |
(katA) catalase/(hydro)peroxidase [KatAB (VF0168) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Tbp
|
tbpA
|
0.0000033 |
1 |
VF0046
|
Nutritional/Metabolic factor |
(tbpA) transferrin-binding protein A [Tbp (VF0046) - Nutritional/Metabolic factor (VFC0272)] [Neisseria meningitidis MC58]
|
|
HpuAB
|
hpuB
|
0.0000067 |
1 |
VF0049
|
Nutritional/Metabolic factor |
(hpuB) haemoglobin-haptoglobin-utilization protein [HpuAB (VF0049) - Nutritional/Metabolic factor (VFC0272)] [Neisseria meningitidis Z2491]
|
|
SodB
|
sodB
|
1.0003359 |
300,634 |
VF0169
|
Stress survival |
(sodB) superoxide dismutase [SodB (VF0169) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
HmbR
|
hmbR
|
0.0000033 |
1 |
VF0048
|
Nutritional/Metabolic factor |
(hmbR) hemoglobin receptor [HmbR (VF0048) - Nutritional/Metabolic factor (VFC0272)] [Neisseria meningitidis MC58]
|
|
Curli fibers
|
csgA
|
0.0001297 |
35 |
VF1138
|
Adherence |
(csgB) curlin minor subunit CsgB [Curli fibers (VF1138) - Adherence (VFC0001)] [Escherichia coli O25b:H4-ST131]
|
|
T4P
|
pilS
|
0.7251315 |
24,819 |
VF0966
|
Invasion |
(pilQ) Flp pilus assembly complex ATPase component TadA [T4P (VF0966) - Invasion (VFC0083)] [Salmonella enterica subsp. enterica serovar Typhi str. CT18]
|
|
PagN
|
pagN
|
1.0111983 |
300,595 |
VF0968
|
Invasion |
(pagN) outer membrane adhesin/invasin protein [PagN (VF0968) - Invasion (VFC0083)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
ChiRP
|
pilA
|
0.00001 |
3 |
VF0609
|
Adherence |
(pilB) type IV-A pilus assembly ATPase PilB [ChiRP (VF0609) - Adherence (VFC0001)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
FeoAB
|
feoB
|
0.0000831 |
23 |
VF0160
|
Nutritional/Metabolic factor |
(feoB) ferrous iron transporter B [FeoAB (VF0160) - Nutritional/Metabolic factor (VFC0272)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Capsule
|
bcs1'
|
0.0000033 |
1 |
VF0043
|
Immune modulation |
(bcs1') Bcs1' [Capsule (VF0043) - Immune modulation (VFC0258)] [Haemophilus influenzae str. 1007]
|
|
ArtAB
|
artB
|
0.0453186 |
8,017 |
VF1366
|
Exotoxin |
(artB) ADP-ribosyltransferase toxin subunit ArtB [ArtAB (VF1366) - Exotoxin (VFC0235)] [Salmonella enterica subsp. enterica serovar Typhimurium str. DT104]
|
|
MisL
|
misL
|
1.1587217 |
296,726 |
VF0397
|
Adherence |
(misL) putative autotransporter [MisL (VF0397) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Type IV pili
|
pilT
|
0.0000299 |
9 |
VF0155
|
Adherence |
(pilT) type IV pilus twitching motility protein PilT [Type IV pili (VF0155) - Adherence (VFC0001)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
LPS
|
bplF
|
0.00001 |
3 |
VF0033
|
Immune modulation |
(bplC) lipopolysaccharide biosynthesis protein [LPS (VF0033) - Immune modulation (VFC0258)] [Bordetella pertussis Tohama I]
|
|
Mig-5
|
mig-5
|
0.2512181 |
75,378 |
VF0396
|
Antimicrobial activity/Competitive advantage |
(mig-5) putative carbonic anhydrase [Mig-5 (VF0396) - Antimicrobial activity/Competitive advantage (VFC0325)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Lsp T2SS
|
lspG
|
0.0000033 |
1 |
VF0154
|
Effector delivery system |
(lspG) general secretion pathway protein G [Lsp T2SS (VF0154) - Effector delivery system (VFC0086)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Lmb
|
lmb
|
0.0000033 |
1 |
VF0275
|
Adherence |
(lmb) laminin-binding surface protein [Lmb (VF0275) - Adherence (VFC0001)] [Streptococcus agalactiae NEM316]
|
|
Flagella
|
fliC
|
0.0002428 |
61 |
VF0157
|
Motility |
(motB) flagellar motor protein MotB [Flagella (VF0157) - Motility (VFC0204)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
RatB
|
ratB
|
1.1963575 |
268,239 |
VF0399
|
Adherence |
(ratB) putative outer membrane protein [RatB (VF0399) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Haemagglutinating pili
|
hifB
|
0.0000133 |
4 |
VF0036
|
Adherence |
(hifB) periplasmic chaperone [Haemagglutinating pili (VF0036) - Adherence (VFC0001)] [Haemophilus influenzae AM30 (770235)]
|
|
MgtC
|
mgtC
|
0.9998004 |
299,949 |
VF1365
|
Nutritional/Metabolic factor |
(mgtC) Salmonella virulence protein MgtC [MgtC (VF1365) - Nutritional/Metabolic factor (VFC0272)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
ShdA
|
shdA
|
1.0579737 |
218,782 |
VF0398
|
Adherence |
(shdA) AIDA autotransporter-like protein [ShdA (VF0398) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
TTSS
|
bscN
|
0.00001 |
3 |
VF0035
|
Effector delivery system |
(bscN) ATP synthase in type III secretion system [TTSS (VF0035) - Effector delivery system (VFC0086)] [Bordetella pertussis Tohama I]
|
|
Hsp60
|
htpB
|
1.0199554 |
300,642 |
VF0159
|
Adherence |
(htpB) Hsp60, 60K heat shock protein HtpB [Hsp60 (VF0159) - Adherence (VFC0001)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
HMW1/HMW2
|
hmw2C
|
0.0000033 |
1 |
VF0038
|
Adherence |
(hmw2C) glycosyltransferase [HMW1/HMW2 (VF0038) - Adherence (VFC0001)] [Haemophilus influenzae str. 12]
|
|
TTSS secreted effectors
|
CT_135
|
0.0000067 |
2 |
VF0711
|
Effector delivery system |
(glgA) glycogen synthase [TTSS secreted effectors (VF0711) - Effector delivery system (VFC0086)] [Chlamydia trachomatis D/UW-3/CX]
|
|
CNFy
|
cnf
|
0.0008381 |
252 |
VF0393
|
Exotoxin |
(cnf) cytotoxic necrotizing factor [CNFy (VF0393) - Exotoxin (VFC0235)] [Yersinia pseudotuberculosis YPIII]
|
|
FbpABC
|
fbpC
|
0.0000166 |
4 |
VF0272
|
Nutritional/Metabolic factor |
(fbpC) iron(III) ABC transporter, ATP-binding protein [FbpABC (VF0272) - Nutritional/Metabolic factor (VFC0272)] [Neisseria meningitidis MC58]
|
|
PsaA
|
psaA
|
0.0000067 |
1 |
VF0151
|
Nutritional/Metabolic factor |
(psaA) manganese ABC transporter, manganese-binding adhesion liprotein [PsaA (VF0151) - Nutritional/Metabolic factor (VFC0272)] [Streptococcus pneumoniae TIGR4]
|
|
O-antigen
|
YE_RS15460
|
1.4870473 |
229,419 |
VF0392
|
Immune modulation |
(YE_RS15420) mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase [O-antigen (VF0392) - Immune modulation (VFC0258)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
Mig-14
|
mig-14
|
1.0237502 |
300,336 |
VF0395
|
Antimicrobial activity/Competitive advantage |
(mig-14) antimicrobial peptide resistance protein Mig-14 [Mig-14 (VF0395) - Antimicrobial activity/Competitive advantage (VFC0325)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Capsule
|
neuA
|
0.0000166 |
5 |
VF0274
|
Immune modulation |
(neuA) N-acylneuraminate cytidylyltransferase [Capsule (VF0274) - Immune modulation (VFC0258)] [Streptococcus agalactiae NEM316]
|
|
Flagella
|
fleI/flaG
|
0.0003891 |
60 |
VF0273
|
Motility |
(motB) flagellar motor protein [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1]
|
|
Flagella
|
motB
|
32.2145767 |
300,662 |
VF0394
|
Motility |
(fliL) flagellar basal body protein FliL [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
PspA
|
pspA
|
0.0000033 |
1 |
VF0152
|
Immune modulation |
(pspA) surface protein A [PspA (VF0152) - Immune modulation (VFC0258)] [Streptococcus pneumoniae TIGR4]
|
|
Fimbriae
|
fimB
|
0.0000033 |
1 |
VF0031
|
Adherence |
(fimB) chaperone protein [Fimbriae (VF0031) - Adherence (VFC0001)] [Bordetella pertussis Tohama I]
|
|
Ysa TTSS effectors
|
YE_RS12240
|
0.0026275 |
790 |
VF1037
|
Effector delivery system |
(YE_RS12240) protein kinase [Ysa TTSS effectors (VF1037) - Effector delivery system (VFC0086)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
ActA
|
actA
|
0.0000067 |
2 |
VF0066
|
Motility |
(actA) actin-assembly inducing protein precursor [ActA (VF0066) - Motility (VFC0204)] [Listeria monocytogenes EGD-e]
|
|
InlA
|
inlA
|
0.0000033 |
1 |
VF0069
|
Invasion |
(inlA) Internalin A [InlA (VF0069) - Invasion (VFC0083)] [Listeria monocytogenes EGD-e]
|
|
Ler
|
AAC38364
|
0.0013304 |
400 |
VF0189
|
Regulation |
(AAC38364) Orf1 [Ler (VF0189) - Regulation (VFC0301)] [Escherichia coli O127:H6 str. E2348/69]
|
|
P60
|
iap/cwhA
|
0.0000033 |
1 |
VF0068
|
Invasion |
(iap/cwhA) P60 extracellular protein, invasion associated protein Iap [P60 (VF0068) - Invasion (VFC0083)] [Listeria monocytogenes EGD-e]
|
|
AdeFGH efflux pump
|
adeG
|
0.9800247 |
284,989 |
VF0504
|
Biofilm |
(adeG) cation/multidrug efflux pump [AdeFGH efflux pump (VF0504) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU]
|
|
FdeC
|
fdeC
|
0.2464155 |
73,983 |
VF0506
|
Adherence |
(fdeC) adhesin FdeC [FdeC (VF0506) - Adherence (VFC0001)] [Escherichia coli O45:K1:H7 str. S88]
|
|
PlcA
|
plcA
|
0.0000067 |
2 |
VF0063
|
Exotoxin |
(plcA) phosphatidylinositol-specific phospholipase c [PlcA (VF0063) - Exotoxin (VFC0235)] [Listeria monocytogenes EGD-e]
|
|
PrfA
|
prfA
|
0.0000033 |
1 |
VF0062
|
Regulation |
(prfA) listeriolysin positive regulatory protein [PrfA (VF0062) - Regulation (VFC0301)] [Listeria monocytogenes EGD-e]
|
|
Mpl
|
mpl
|
0.0000033 |
1 |
VF0065
|
Exoenzyme |
(mpl) Zinc metalloproteinase precursor [Mpl (VF0065) - Exoenzyme (VFC0251)] [Listeria monocytogenes EGD-e]
|
|
CDT
|
cdtA
|
0.011022 |
3,184 |
VF0185
|
Exotoxin |
(cdtA) cytolethal distending toxin A [CDT (VF0185) - Exotoxin (VFC0235)] [Escherichia coli O157:H str. 493/89]
|
|
LLO
|
hly
|
0.0000067 |
2 |
VF0064
|
Exotoxin |
(hly) listeriolysin O precursor [LLO (VF0064) - Exotoxin (VFC0235)] [Listeria monocytogenes EGD-e]
|
|
MprAB
|
mprA
|
0.0000233 |
7 |
VF0298
|
Regulation |
(mprA) two-component response regulator MrpA [MprAB (VF0298) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
LPS
|
rfbD
|
0.0000565 |
17 |
VF0056
|
Immune modulation |
(rfbD) GDP-D-mannose dehydratase [LPS (VF0056) - Immune modulation (VFC0258)] [Helicobacter pylori 26695]
|
|
Ysa TTSS
|
ysaR
|
0.0000299 |
6 |
VF1025
|
Effector delivery system |
(ysaT) type III secretion system export apparatus subunit SctT [Ysa TTSS (VF1025) - Effector delivery system (VFC0086)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
Intimin
|
eae
|
0.0000266 |
8 |
VF0177
|
Effector delivery system |
(eae) intimin [Intimin (VF0177) - Effector delivery system (VFC0086)] [Escherichia coli O127:H6 str. E2348/69]
|
|
BapA
|
bapA
|
1.0281238 |
300,485 |
VF0971
|
Adherence |
|
|
VacA
|
vacA
|
0.0000033 |
1 |
VF0058
|
Exotoxin |
(vacA) vacuolating cytotoxin [VacA (VF0058) - Exotoxin (VFC0235)] [Helicobacter pylori 26695]
|
|
SiiE
|
siiE
|
1.3054036 |
300,376 |
VF0970
|
Adherence |
(siiE) non-fimbrial adhesin SiiE [SiiE (VF0970) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Flp pili
|
VV1_RS15610
|
0.00001 |
3 |
VF0612
|
Adherence |
(VV1_RS15610) CpaF family protein [Flp pili (VF0612) - Adherence (VFC0001)] [Vibrio vulnificus CMCP6]
|
|
SCI (Salmonella centrisome island)/SPI-6 T6SS
|
tssJ
|
16.3599117 |
292,675 |
VF0974
|
Effector delivery system |
|
|
TTSS secreted effectors
|
exoT
|
0.0000067 |
2 |
VF0853
|
Effector delivery system |
(exoT) type III secretion system effector ExoT, ADP ribosyltransferase activity and GTPase-activating protein activity [TTSS secreted effectors (VF0853) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
Eps T2SS
|
epsG
|
0.0000432 |
11 |
VF0613
|
Effector delivery system |
(epsK) type II secretion system minor pseudopilin GspK [Eps T2SS (VF0613) - Effector delivery system (VFC0086)] [Vibrio cholerae O395]
|
|
TTSS secreted effectors
|
ipaJ
|
0.0051285 |
1,488 |
VF0978
|
Effector delivery system |
(ospG) type III secretion system effector OspG, protein kinase [TTSS secreted effectors (VF0978) - Effector delivery system (VFC0086)] [Shigella flexneri 2a str. 301]
|
|
GbpA
|
gbpA
|
0.0000033 |
1 |
VF0619
|
Adherence |
(gbpA) N-acetylglucosamine-binding protein GbpA [GbpA (VF0619) - Adherence (VFC0001)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
CcmC
|
ccmF
|
0.0187946 |
4,944 |
VF0292
|
Nutritional/Metabolic factor |
(ccmC) cytochrome c-type biogenesis protein CcmC, putative heme lyase for CcmE [CcmC (VF0292) - Nutritional/Metabolic factor (VFC0272)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
LPS
|
rfbC
|
0.0059966 |
1,799 |
VF0171
|
Immune modulation |
(LPG_RS03775) NAD-dependent epimerase/dehydratase family protein [LPS (VF0171) - Immune modulation (VFC0258)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Urease
|
ureG
|
0.0003326 |
54 |
VF0050
|
Stress survival |
(ureG) urease accessory protein (ureG) [Urease (VF0050) - Stress survival (VFC0282)] [Helicobacter pylori 26695]
|
|
EspC
|
espC
|
0.0006519 |
191 |
VF0173
|
Effector delivery system |
(espC) Type III secretion system secreted protein, serine protease [EspC (VF0173) - Effector delivery system (VFC0086)] [Escherichia coli O127:H6 str. E2348/69]
|
|
TTSS secreted effectors
|
yopJ/yopP
|
0.0000599 |
18 |
VF1021
|
Effector delivery system |
(yopJ/yopP) type III secretion system effector YopP/YopJ, acetyltransferase [TTSS secreted effectors (VF1021) - Effector delivery system (VFC0086)] [Yersinia pestis CO92]
|
|
TTSS
|
escD
|
0.0116307 |
641 |
VF0172
|
Effector delivery system |
(cesD2) chaperone for EspD [TTSS (VF0172) - Effector delivery system (VFC0086)] [Escherichia coli O127:H6 str. E2348/69]
|
|
IraAB
|
iraB
|
0.0000067 |
2 |
VF0293
|
Nutritional/Metabolic factor |
(iraB) Di/tripeptide permease [IraAB (VF0293) - Nutritional/Metabolic factor (VFC0272)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Flagella
|
pdxA
|
0.0000166 |
5 |
VF0051
|
Motility |
(tlpA) membrane-bound chemoreceptor sensing arginine and bicarbonate [Flagella (VF0051) - Motility (VFC0204)] [Helicobacter pylori 26695]
|
|
SigH
|
sigH
|
0.0000067 |
1 |
VF0296
|
Regulation |
(sigH) ECF RNA polymerase sigma factor SigH [SigH (VF0296) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
BFP
|
bfpU
|
0.0004856 |
117 |
VF0174
|
Adherence |
(bfpP) prepilin peptidase BfpP [BFP (VF0174) - Adherence (VFC0001)] [Escherichia coli O127:H6 str. E2348/69]
|
|
SigE
|
sigE
|
0.0000033 |
1 |
VF0295
|
Regulation |
(sigE) ECF RNA polymerase sigma factor SigE [SigE (VF0295) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
BabA
|
babA/hopS
|
0.0000033 |
1 |
VF0053
|
Adherence |
(babA/hopS) outer membrane protein adhesin [BabA (VF0053) - Adherence (VFC0001)] [Helicobacter pylori 26695]
|