| QnrD1 |
ARO:3002788 |
1 |
fluoroquinolone antibiotic |
antibiotic target protection |
quinolone resistance protein (qnr) |
| CDD-1 |
ARO:3006904 |
7,940 |
carbapenem |
antibiotic inactivation |
CDD beta-lactamase |
| ANT(4')-Ia |
ARO:3002623 |
1 |
aminoglycoside antibiotic |
antibiotic inactivation |
ANT(4') |
| efmA |
ARO:3003954 |
1 |
macrolide antibiotic; fluoroquinolone antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| CDD-2 |
ARO:3006905 |
3,278 |
carbapenem |
antibiotic inactivation |
CDD beta-lactamase |
| cdeA |
ARO:3003835 |
12,291 |
fluoroquinolone antibiotic; disinfecting agents and antiseptics |
antibiotic efflux |
multidrug and toxic compound extrusion (MATE) transporter |
| dfrF |
ARO:3002867 |
235 |
diaminopyrimidine antibiotic |
antibiotic target replacement |
trimethoprim resistant dihydrofolate reductase dfr |
| cfr(B) |
ARO:3004649 |
59 |
lincosamide antibiotic; streptogramin antibiotic; oxazolidinone antibiotic; phenicol antibiotic |
antibiotic target alteration |
Cfr 23S ribosomal RNA methyltransferase |
| ANT(6)-Ia |
ARO:3002626 |
221 |
aminoglycoside antibiotic |
antibiotic inactivation |
ANT(6) |
| Clostridioides difficile gyrA conferring resistance to fluoroquinolones |
ARO:3003995 |
2,321 |
fluoroquinolone antibiotic |
antibiotic target alteration |
fluoroquinolone resistant gyrA |
| tet(40) |
ARO:3000567 |
339 |
tetracycline antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| npmA |
ARO:3002665 |
43 |
aminoglycoside antibiotic |
antibiotic target alteration |
16S rRNA methyltransferase (A1408) |
| ErmG |
ARO:3000522 |
17 |
macrolide antibiotic; lincosamide antibiotic; streptogramin antibiotic; streptogramin A antibiotic; streptogramin B antibiotic |
antibiotic target alteration |
Erm 23S ribosomal RNA methyltransferase |
| LnuP |
ARO:3004601 |
2 |
lincosamide antibiotic |
antibiotic inactivation |
lincosamide nucleotidyltransferase (LNU) |
| nimJ |
ARO:3007112 |
38 |
nitroimidazole antibiotic |
antibiotic inactivation |
nitroimidazole reductase |
| tet(45) |
ARO:3003196 |
2 |
tetracycline antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| aadA27 |
ARO:3004682 |
1 |
aminoglycoside antibiotic |
antibiotic inactivation |
ANT(3'') |
| 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) |
ARO:3005099 |
11 |
macrolide antibiotic; lincosamide antibiotic; streptogramin antibiotic |
antibiotic target alteration |
Erm 23S ribosomal RNA methyltransferase |
| Bifidobacterium adolescentis rpoB mutants conferring resistance to rifampicin |
ARO:3004480 |
1 |
rifamycin antibiotic |
antibiotic target alteration; antibiotic target replacement |
rifamycin-resistant beta-subunit of RNA polymerase (rpoB) |
| efrA |
ARO:3003948 |
1 |
macrolide antibiotic; fluoroquinolone antibiotic; rifamycin antibiotic |
antibiotic efflux |
ATP-binding cassette (ABC) antibiotic efflux pump |
| vanS gene in vanG cluster |
ARO:3002937 |
8 |
glycopeptide antibiotic |
antibiotic target alteration |
vanS; glycopeptide resistance gene cluster |
| vanS gene in vanA cluster |
ARO:3002931 |
1 |
glycopeptide antibiotic |
antibiotic target alteration |
vanS; glycopeptide resistance gene cluster |
| QnrB19 |
ARO:3002734 |
1 |
fluoroquinolone antibiotic |
antibiotic target protection |
quinolone resistance protein (qnr) |
| ErmT |
ARO:3000595 |
2 |
macrolide antibiotic; lincosamide antibiotic; streptogramin antibiotic; streptogramin A antibiotic; streptogramin B antibiotic |
antibiotic target alteration |
Erm 23S ribosomal RNA methyltransferase |
| clcD |
ARO:3004599 |
41 |
lincosamide antibiotic; streptogramin antibiotic; streptogramin A antibiotic; streptogramin B antibiotic; oxazolidinone antibiotic; phenicol antibiotic; pleuromutilin antibiotic |
antibiotic target alteration |
Cfr 23S ribosomal RNA methyltransferase |
| vanT gene in vanG cluster |
ARO:3002972 |
12,414 |
glycopeptide antibiotic |
antibiotic target alteration |
glycopeptide resistance gene cluster; vanT |
| tet(44) |
ARO:3000556 |
79 |
tetracycline antibiotic |
antibiotic target protection |
tetracycline-resistant ribosomal protection protein |
| SAT-4 |
ARO:3002897 |
398 |
nucleoside antibiotic |
antibiotic inactivation |
streptothricin acetyltransferase (SAT) |
| tet(W) |
ARO:3000194 |
21 |
tetracycline antibiotic |
antibiotic target protection |
tetracycline-resistant ribosomal protection protein |
| tet(T) |
ARO:3000193 |
1 |
tetracycline antibiotic |
antibiotic target protection |
tetracycline-resistant ribosomal protection protein |
| nimA |
ARO:3007104 |
2 |
nitroimidazole antibiotic |
antibiotic inactivation |
nitroimidazole reductase |
| vanXY gene in vanG cluster |
ARO:3003069 |
10,443 |
glycopeptide antibiotic |
antibiotic target alteration |
glycopeptide resistance gene cluster; vanXY |
| vanT gene in vanC cluster |
ARO:3002970 |
1 |
glycopeptide antibiotic |
antibiotic target alteration |
glycopeptide resistance gene cluster; vanT |
| ErmQ |
ARO:3000593 |
19 |
macrolide antibiotic; lincosamide antibiotic; streptogramin antibiotic; streptogramin A antibiotic; streptogramin B antibiotic |
antibiotic target alteration |
Erm 23S ribosomal RNA methyltransferase |
| tet(32) |
ARO:3000196 |
9 |
tetracycline antibiotic |
antibiotic target protection |
tetracycline-resistant ribosomal protection protein |
| tetB(P) |
ARO:3000195 |
144 |
tetracycline antibiotic |
antibiotic target protection |
tetracycline-resistant ribosomal protection protein |
| APH(2'')-If |
ARO:3004191 |
291 |
aminoglycoside antibiotic |
antibiotic inactivation |
APH(2'') |
| tet(O) |
ARO:3000190 |
74 |
tetracycline antibiotic |
antibiotic target protection |
tetracycline-resistant ribosomal protection protein |
| AAC(6')-Im |
ARO:3004629 |
20 |
aminoglycoside antibiotic |
antibiotic inactivation |
AAC(6') |
| vanR gene in vanG cluster |
ARO:3002926 |
10 |
glycopeptide antibiotic |
antibiotic target alteration |
glycopeptide resistance gene cluster; vanR |
| vanW gene in vanG cluster |
ARO:3002965 |
13 |
glycopeptide antibiotic |
antibiotic target alteration |
vanW; glycopeptide resistance gene cluster |
| APH(3')-IIIa |
ARO:3002647 |
437 |
aminoglycoside antibiotic |
antibiotic inactivation |
APH(3') |
| APH(3')-Ia |
ARO:3002641 |
1 |
aminoglycoside antibiotic |
antibiotic inactivation |
APH(3') |
| catP |
ARO:3002686 |
95 |
phenicol antibiotic |
antibiotic inactivation |
chloramphenicol acetyltransferase (CAT) |
| vanY gene in vanM cluster |
ARO:3002961 |
1 |
glycopeptide antibiotic |
antibiotic target alteration |
vanY; glycopeptide resistance gene cluster |
| rpsJ |
ARO:3003930 |
1 |
tetracycline antibiotic |
antibiotic target protection |
tetracycline-resistant ribosomal protection protein |
| catS |
ARO:3002688 |
1 |
phenicol antibiotic |
antibiotic inactivation |
chloramphenicol acetyltransferase (CAT) |
| catI |
ARO:3002683 |
1 |
phenicol antibiotic |
antibiotic inactivation |
chloramphenicol acetyltransferase (CAT) |
| qacG |
ARO:3007015 |
3 |
disinfecting agents and antiseptics |
antibiotic efflux |
small multidrug resistance (SMR) antibiotic efflux pump |
| qacJ |
ARO:3007014 |
2 |
disinfecting agents and antiseptics |
antibiotic efflux |
small multidrug resistance (SMR) antibiotic efflux pump |
| tet(M) |
ARO:3000186 |
2,153 |
tetracycline antibiotic |
antibiotic target protection |
tetracycline-resistant ribosomal protection protein |
| QnrB5 |
ARO:3002719 |
4 |
fluoroquinolone antibiotic |
antibiotic target protection |
quinolone resistance protein (qnr) |
| TEM-116 |
ARO:3000979 |
1 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| vanR gene in vanA cluster |
ARO:3002919 |
1 |
glycopeptide antibiotic |
antibiotic target alteration |
glycopeptide resistance gene cluster; vanR |
| lnuB |
ARO:3002836 |
1 |
lincosamide antibiotic |
antibiotic inactivation |
lincosamide nucleotidyltransferase (LNU) |
| lnuC |
ARO:3002837 |
36 |
lincosamide antibiotic |
antibiotic inactivation |
lincosamide nucleotidyltransferase (LNU) |
| vanY gene in vanF cluster |
ARO:3002958 |
12,306 |
glycopeptide antibiotic |
antibiotic target alteration |
vanY; glycopeptide resistance gene cluster |
| vanY gene in vanG cluster |
ARO:3002959 |
12,409 |
glycopeptide antibiotic |
antibiotic target alteration |
vanY; glycopeptide resistance gene cluster |
| lsaE |
ARO:3003206 |
1 |
lincosamide antibiotic; streptogramin antibiotic; pleuromutilin antibiotic |
antibiotic target protection |
lsa-type ABC-F protein |
| tet(L) |
ARO:3000179 |
3 |
tetracycline antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| vanW gene in vanI cluster |
ARO:3003724 |
12,418 |
glycopeptide antibiotic |
antibiotic target alteration |
vanW; glycopeptide resistance gene cluster |
| APH(2'')-IIa |
ARO:3002635 |
20 |
aminoglycoside antibiotic |
antibiotic inactivation |
APH(2'') |
| FosXCC |
ARO:3003208 |
77 |
phosphonic acid antibiotic |
antibiotic inactivation |
fosfomycin thiol transferase |
| vanY gene in vanA cluster |
ARO:3002955 |
30 |
glycopeptide antibiotic |
antibiotic target alteration |
vanY; glycopeptide resistance gene cluster |
| lnuA |
ARO:3002835 |
2 |
lincosamide antibiotic |
antibiotic inactivation |
lincosamide nucleotidyltransferase (LNU) |
| ErmB |
ARO:3000375 |
2,239 |
macrolide antibiotic; lincosamide antibiotic; streptogramin antibiotic; streptogramin A antibiotic; streptogramin B antibiotic |
antibiotic target alteration |
Erm 23S ribosomal RNA methyltransferase |
| vanY gene in vanB cluster |
ARO:3002956 |
32 |
glycopeptide antibiotic |
antibiotic target alteration |
vanY; glycopeptide resistance gene cluster |
| APH(2'')-IVa |
ARO:3002637 |
21 |
aminoglycoside antibiotic |
antibiotic inactivation |
APH(2'') |
| ANT(9)-Ia |
ARO:3002630 |
1 |
aminoglycoside antibiotic |
antibiotic inactivation |
ANT(9) |
| AAC(6')-Ie-APH(2'')-Ia bifunctional protein |
ARO:3002597 |
879 |
aminoglycoside antibiotic |
antibiotic inactivation |
aminoglycoside bifunctional resistance protein |
| FosB3 |
ARO:3002873 |
10 |
phosphonic acid antibiotic |
antibiotic inactivation |
fosfomycin thiol transferase |
| AAC(6')-Ii |
ARO:3002556 |
1 |
aminoglycoside antibiotic |
antibiotic inactivation |
AAC(6') |
| dfrE |
ARO:3002875 |
1 |
diaminopyrimidine antibiotic |
antibiotic target replacement |
trimethoprim resistant dihydrofolate reductase dfr |
| tet(U) |
ARO:3004650 |
1 |
tetracycline antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| CfxA3 |
ARO:3003003 |
1 |
cephamycin |
antibiotic inactivation |
CfxA beta-lactamase |
| mefH |
ARO:3007047 |
296 |
macrolide antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| cfrE |
ARO:3005023 |
87 |
lincosamide antibiotic; streptogramin antibiotic; oxazolidinone antibiotic; phenicol antibiotic |
antibiotic target alteration |
Cfr 23S ribosomal RNA methyltransferase |
| vanU gene in vanG cluster |
ARO:3004253 |
12 |
glycopeptide antibiotic |
antibiotic target alteration |
glycopeptide resistance gene cluster; vanU |
| ErmC |
ARO:3000250 |
1 |
macrolide antibiotic; lincosamide antibiotic; streptogramin antibiotic; streptogramin A antibiotic; streptogramin B antibiotic |
antibiotic target alteration |
Erm 23S ribosomal RNA methyltransferase |
| Erm(52) |
ARO:3007041 |
104 |
macrolide antibiotic; lincosamide antibiotic; streptogramin antibiotic |
antibiotic target alteration |
Erm 23S ribosomal RNA methyltransferase |
| ANT(3'')-IIc |
ARO:3004091 |
1 |
aminoglycoside antibiotic |
antibiotic inactivation |
ANT(3'') |
| apmA |
ARO:3003918 |
3 |
aminoglycoside antibiotic |
antibiotic inactivation |
AAC(2') |
| vanG |
ARO:3002909 |
10,434 |
glycopeptide antibiotic |
antibiotic target alteration |
glycopeptide resistance gene cluster; Van ligase |
| aad(6) |
ARO:3002628 |
395 |
aminoglycoside antibiotic |
antibiotic inactivation |
ANT(6) |
| vanH gene in vanO cluster |
ARO:3002948 |
1 |
glycopeptide antibiotic |
antibiotic target alteration |
vanH; glycopeptide resistance gene cluster |
| ANT(6)-Ib |
ARO:3002629 |
87 |
aminoglycoside antibiotic |
antibiotic inactivation |
ANT(6) |