Clostridioides difficile

艰难拟梭菌
Virulence Factors: Temporal Map
VFs in isolation sources
List
Virulence factor Related gene Frequency Genomes statistics VF ID VF function Description
Capsule cap8D 0.0007973 7 VF0003 Immune modulation (cap8D) type 8 capsular polysaccharide synthesis protein Cap8D [Capsule (VF0003) - Immune modulation (VFC0258)] [Staphylococcus aureus subsp. aureus MW2]
Hyaluronic acid capsule hasB 0.0025691 23 VF0244 Immune modulation (hasB) UDP-glucose 6-dehydrogenase HasB [Hyaluronic acid capsule (VF0244) - Immune modulation (VFC0258)] [Streptococcus pyogenes M1 GAS]
LPS gmd 0.0000886 1 VF0367 Immune modulation (gmd) GDP-mannose 4,6-dehydratase [LPS (VF0367) - Immune modulation (VFC0258)] [Brucella melitensis bv. 1 str. 16M]
Porin porB 0.0000886 1 VF0081 Invasion (porB) major outer membrane protein PIB [Porin (VF0081) - Invasion (VFC0083)] [Neisseria meningitidis MC58]
IgA1 protease iga 0.0000886 1 VF0080 Effector delivery system (iga) IgA-specific serine endopeptidase [IgA1 protease (VF0080) - Effector delivery system (VFC0086)] [Neisseria meningitidis MC58]
Type IV pili rpoS 0.0001772 2 VF0082 Adherence (pilR) two-component response regulator PilR [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1]
LPS wbpM 0.0000886 1 VF0085 Immune modulation (wbpM) nucleotide sugar epimerase/dehydratase WbpM [LPS (VF0085) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1]
BopD bopD 0.0000886 1 VF0362 Biofilm (bopD) sugar-binding transcriptional regulator, LacI family [BopD (VF0362) - Biofilm (VFC0271)] [Enterococcus faecalis V583]
Capsule cpsB/cdsA 0.0002658 2 VF0361 Immune modulation (cpsB/cdsA) phosphatidate cytidylyltransferase [Capsule (VF0361) - Immune modulation (VFC0258)] [Enterococcus faecalis V583]
LOS rfaC 0.0001772 1 VF0078 Immune modulation (rfaC) lipopolysaccharide heptosyltransferase I [LOS (VF0078) - Immune modulation (VFC0258)] [Neisseria meningitidis MC58]
FbpA/Fbp68 fbpA/fbp68 1.0644047 11,277 VF0595 Adherence (fbpA/fbp68) fibronectin-binding protein FbpA [FbpA/Fbp68 (VF0595) - Adherence (VFC0001)] [Clostridium difficile 630]
Esp esp 0.0001772 1 VF0353 Adherence (esp) Enterococcal surface protein; Esp [Esp (VF0353) - Adherence (VFC0001)] [Enterococcus faecalis str. MMH594]
GroEL groEL 1.003455 11,278 VF0594 Adherence (groEL) chaperonin GroEL [GroEL (VF0594) - Adherence (VFC0001)] [Clostridium difficile 630]
Polar flagella flmH 0.0007087 8 VF0473 Motility (flmH) short chain dehydrogenase/reductase family oxidoreductase [Polar flagella (VF0473) - Motility (VFC0204)] [Aeromonas hydrophila ML09-119]
Ace ace 0.0000886 1 VF0355 Adherence (ace) collagen adhesin protein [Ace (VF0355) - Adherence (VFC0001)] [Enterococcus faecalis V583]
CwpV cwpV 0.5472183 3,873 VF0596 Adherence (cwpV) hemagglutinin/adhesin [CwpV (VF0596) - Adherence (VFC0001)] [Clostridium difficile 630]
EfaA efaA 0.0000886 1 VF0354 Adherence (efaA) endocarditis specific antigen [EfaA (VF0354) - Adherence (VFC0001)] [Enterococcus faecalis V583]
Capsule siaB/synB 0.0003544 1 VF0079 Immune modulation (siaB/synB) polysialic acid capsule biosynthesis protein SiaB [Capsule (VF0079) - Immune modulation (VFC0258)] [Neisseria meningitidis MC58]
CD3246 CD3246 0.9794472 9,834 VF0599 Adherence (CD3246) Cys-Gln thioester bond-forming surface protein [CD3246 (VF0599) - Adherence (VFC0001)] [Clostridium difficile 630]
CD2831 CD2831 1.04146 11,279 VF0598 Adherence (CD2831) SrtB-anchored collagen-binding adhesin [CD2831 (VF0598) - Adherence (VFC0001)] [Clostridium difficile 630]
Flagella flgR 0.0879695 991 VF0114 Motility (fliP) flagellar biosynthesis protein FliP [Flagella (VF0114) - Motility (VFC0204)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
Hyaluronidase EF3023 0.0000886 1 VF0359 Exoenzyme (EF3023) polysaccharide lyase, family 8 [Hyaluronidase (VF0359) - Exoenzyme (VFC0251)] [Enterococcus faecalis V583]
T3SS ascN 0.0005315 6 VF0479 Effector delivery system (ascN) Type III secretion system ATPase [T3SS (VF0479) - Effector delivery system (VFC0086)] [Aeromonas salmonicida subsp. salmonicida A449]
Ibes ibeC 0.0000886 1 VF0237 Invasion (ibeC) phosphoethanolamine transferase CptA [Ibes (VF0237) - Invasion (VFC0083)] [Escherichia coli O45:K1:H7 str. S88]
K1 capsule neuB 0.0000886 1 VF0239 Invasion (neuB) N-acylneuraminate-9-phosphate synthase [K1 capsule (VF0239) - Invasion (VFC0083)] [Escherichia coli O45:K1:H7 str. S88]
Flagella flrA 0.0001772 2 VF0519 Motility (flrA) sigma-54 dependent transcriptional activator [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961]
ClpC clpC 0.0027463 27 VF0072 Stress survival (clpC) endopeptidase Clp ATP-binding chain C [ClpC (VF0072) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
Cwp66 cwp66 0.9461375 10,589 VF0591 Adherence (cwp66) cell wall-binding protein Cwp66 [Cwp66 (VF0591) - Adherence (VFC0001)] [Clostridium difficile 630]
ClpP clpP 2.0541283 11,286 VF0074 Stress survival (clpP) ATP-dependent Clp protease proteolytic subunit [ClpP (VF0074) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
ClpE clpE 0.0001772 2 VF0073 Stress survival (clpE) ATP-dependent protease [ClpE (VF0073) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
Cwp84 cwp84 2.0091247 11,286 VF0590 Exoenzyme (cwp84) cell wall-binding cysteine protease Cwp84 [Cwp84 (VF0590) - Exoenzyme (VFC0251)] [Clostridium difficile 630]
CD0873 CD0873 1.8744685 11,284 VF0593 Adherence (CD0873) ABC transporter substrate-binding protein [CD0873 (VF0593) - Adherence (VFC0001)] [Clostridium difficile 630]
BSH bsh 0.0001772 1 VF0350 Stress survival (bsh) bile salt hydrolase [BSH (VF0350) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
CbpA cbpA 1.1598157 10,036 VF0592 Adherence (cbpA) collagen-binding adhesin CbpA [CbpA (VF0592) - Adherence (VFC0001)] [Clostridium difficile 630]
Type IV pili pilH 0.0005315 4 VF0075 Adherence (pilE) Type IV pilus major pilin subunit PilE [Type IV pili (VF0075) - Adherence (VFC0001)] [Neisseria meningitidis MC58]
PmrAB pmrB 0.0000886 1 VF1355 Regulation (pmrB) sensory kinase PmrB [PmrAB (VF1355) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
SgrA sgrA 0.0000886 1 VF0540 Adherence (sgrA) cell wall anchored protein SgrA [SgrA (VF0540) - Adherence (VFC0001)] [Enterococcus faecium DO]
Capsule cps4I 1.0004429 11,275 VF0144 Immune modulation (cps4I) capsular polysaccharide biosynthesis protein Cps4I [Capsule (VF0144) - Immune modulation (VFC0258)] [Streptococcus pneumoniae TIGR4]
CDT cdtA 0.6705351 7,035 VF0385 Exotoxin (cdtA) CdtA [CDT (VF0385) - Exotoxin (VFC0235)] [Clostridium difficile 630]
LPS wbtL 0.9446315 9,965 VF0542 Immune modulation (wbtF) NAD dependent epimerase [LPS (VF0542) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4]
Nitrate reductase narG 0.0000886 1 VF0302 Nutritional/Metabolic factor (narG) nitrate reductase subunit alpha [Nitrate reductase (VF0302) - Nutritional/Metabolic factor (VFC0272)] [Mycobacterium tuberculosis H37Rv]
Capsule galE 0.0001772 2 VF0543 Immune modulation (galE) UDP-glucose 4-epimerase GalE [Capsule (VF0543) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4]
HitABC hitC 0.0000886 1 VF0268 Nutritional/Metabolic factor (hitC) iron(III) ABC transporter, ATP-binding protein [HitABC (VF0268) - Nutritional/Metabolic factor (VFC0272)] [Haemophilus influenzae Rd KW20]
HSI-3 PA2359 0.0001772 2 VF0944 Effector delivery system (PA2359) transcriptional regulator [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
HSI-2 PA1663 0.0001772 2 VF0943 Effector delivery system (PA1663) transcriptional regulator [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
T6SS-1 BPS_RS26875 0.0220588 248 VF0429 Effector delivery system (BPS_RS26875) response regulator VirG [T6SS-1 (VF0429) - Effector delivery system (VFC0086)] [Burkholderia pseudomallei K96243]
Bsa T3SS bprA 0.0000886 1 VF0428 Effector delivery system (bprA) HNS-like regulatory protein [Bsa T3SS (VF0428) - Effector delivery system (VFC0086)] [Burkholderia pseudomallei K96243]
TTSS yscN 0.0001772 2 VF0140 Effector delivery system (yscN) type III secretion system ATPase YscN [TTSS (VF0140) - Effector delivery system (VFC0086)] [Yersinia pestis CO92]
Iota-toxin ibp 2.4904323 9,690 VF0381 Exotoxin (ibp) iota toxin component Ib [Iota-toxin (VF0381) - Exotoxin (VFC0235)] [Clostridium perfringens E str. NCIB 10748]
SvpA hbp2 0.0001772 1 VF0263 Nutritional/Metabolic factor (hbp2) hypothetical protein [SvpA (VF0263) - Nutritional/Metabolic factor (VFC0272)] [Listeria monocytogenes EGD-e]
Isocitrate lyase icl 0.0001772 1 VF0253 Others (icl) Isocitrate lyase Icl (isocitrase) (isocitratase) [Isocitrate lyase (VF0253) - Others (VFC0346)] [Mycobacterium tuberculosis H37Rv]
Shu shuV 0.0000886 1 VF0256 Nutritional/Metabolic factor (shuV) ATP-binding component of hemin transport system [Shu (VF0256) - Nutritional/Metabolic factor (VFC0272)] [Shigella dysenteriae Sd197]
TcdB toxB 0.9378987 10,333 VF0377 Exotoxin (toxB) toxin B [TcdB (VF0377) - Exotoxin (VFC0235)] [Clostridium difficile 630]
TcdA toxA 1.4136251 10,348 VF0376 Exotoxin (toxA) toxin A [TcdA (VF0376) - Exotoxin (VFC0235)] [Clostridium difficile 630]
SigA sigA/rpoV 0.0007087 8 VF0257 Regulation (sigA/rpoV) RNA polymerase sigma factor SigA [SigA (VF0257) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
Yersiniabactin ybtQ 0.0000886 1 VF0136 Nutritional/Metabolic factor (ybtQ) yersiniabactin ABC transporter ATP-binding/permease protein YbtQ [Yersiniabactin (VF0136) - Nutritional/Metabolic factor (VFC0272)] [Yersinia pestis CO92]
Isd isdG 0.0000886 1 VF0015 Nutritional/Metabolic factor (isdG) iron-regulated surface determinant protein G [Isd (VF0015) - Nutritional/Metabolic factor (VFC0272)] [Staphylococcus aureus subsp. aureus str. Newman]
RTX protein frpA 0.0005315 1 VF0897 Adherence (frpA) iron-regulated protein FrpA [RTX protein (VF0897) - Adherence (VFC0001)] [Neisseria meningitidis MC58]
Scm scm 0.0002658 2 VF0418 Adherence (scm) collagen adhesin protein Scm [Scm (VF0418) - Adherence (VFC0001)] [Enterococcus faecium DO]
EcbA ecbA/fss3 0.0001772 1 VF0539 Adherence (ecbA/fss3) Collagen binding MSCRAMM, EcbA/Fss3 [EcbA (VF0539) - Adherence (VFC0001)] [Enterococcus faecium DO]
Ebp pili srtC 0.0001772 1 VF0538 Adherence (srtC) sortase [Ebp pili (VF0538) - Adherence (VFC0001)] [Enterococcus faecalis V583]
Acm acm 0.0000886 1 VF0419 Adherence (acm) collagen adhesin precursor Acm [Acm (VF0419) - Adherence (VFC0001)] [Enterococcus faecium str. TX2555]
Alginate algI 0.0002658 3 VF0091 Biofilm (algI) alginate o-acetyltransferase AlgI [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1]
LPS kdsA 0.0000886 1 VF0370 Immune modulation (kdsA) 3-deoxy-8-phosphooctulonate synthase [LPS (VF0370) - Immune modulation (VFC0258)] [Bartonella henselae str. Houston-1]
Flagella flhB 0.0000886 1 VF0373 Motility (flhB) flagellar biosynthetic protein FlhB [Flagella (VF0373) - Motility (VFC0204)] [Bartonella bacilliformis KC583]
RelA relA 0.0000886 1 VF0287 Regulation (relA) Probable GTP pyrophosphokinase RelA (ATP:GTP 3'-pyrophosphotransferase) (PPGPP synthetase I) ((P)PPGPP synthetase) (GTP diphosphokinase) [RelA (VF0287) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
Ent entB 0.0002658 2 VF0562 Nutritional/Metabolic factor (entB) 2,3-dihydro-2,3-dihydroxybenzoate synthetase, isochroismatase [Ent (VF0562) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
OatA oatA 0.0000886 1 VF0441 Immune modulation (oatA) peptidoglycan O-acetyltransferase [OatA (VF0441) - Immune modulation (VFC0258)] [Listeria monocytogenes EGD-e]
LOS rffG 0.0027463 31 VF0044 Immune modulation (galE) UDP-glucose 4-epimerase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20]
KatAB katA 0.0000886 1 VF0168 Stress survival (katA) catalase/(hydro)peroxidase [KatAB (VF0168) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
TTSS (SPI-2 encode) ssaQ 0.0000886 1 VF0321 Effector delivery system (ssaQ) type III secretion system C ring protein SsaQ [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
InlJ inlJ 0.0000886 1 VF0445 Adherence (inlJ) internalin J [InlJ (VF0445) - Adherence (VFC0001)] [Listeria monocytogenes EGD-e]
Capsule glf 0.0001772 2 VF0323 Immune modulation (kpsF) D-arabinose 5-phosphate isomerase [Capsule (VF0323) - Immune modulation (VFC0258)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
Lap lap 0.0013288 11 VF0444 Adherence (lap) Listeria adhesion protein Lap [Lap (VF0444) - Adherence (VFC0001)] [Listeria monocytogenes EGD-e]
AcrAB acrB 0.0000886 1 VF0568 Antimicrobial activity/Competitive advantage (acrB) acriflavine resistance protein B [AcrAB (VF0568) - Antimicrobial activity/Competitive advantage (VFC0325)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
LOS hldE 0.0000886 1 VF0326 Immune modulation (hldE) bifunctional D-beta-D-heptose 7-phosphate kinase/D-beta-D-heptose 1-phosphate adenylyltransferase [LOS (VF0326) - Immune modulation (VFC0258)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
InlF inlF 0.0000886 1 VF0447 Adherence (inlF) internalin F [InlF (VF0447) - Adherence (VFC0001)] [Listeria monocytogenes EGD-e]
Type 3 fimbriae mrkA 0.0000886 1 VF0567 Biofilm (mrkA) type 3 fimbrial major pilin subunit MrkA [Type 3 fimbriae (VF0567) - Biofilm (VFC0271)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
Zmp1 zmp1 1.0002658 11,275 VF0600 Exoenzyme (zmp1) zinc metalloprotease Zmp1 [Zmp1 (VF0600) - Exoenzyme (VFC0251)] [Clostridium difficile 630]
PrsA2 prsA2 0.0000886 1 VF0449 Post-translational modification (prsA2) post translocation chaperone PrsA2 [PrsA2 (VF0449) - Post-translational modification (VFC0315)] [Listeria monocytogenes EGD-e]
FeoAB feoB 0.0007087 7 VF0160 Nutritional/Metabolic factor (feoB) ferrous iron transporter B [FeoAB (VF0160) - Nutritional/Metabolic factor (VFC0272)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
Capsule ugd 0.0004429 4 VF0560 Immune modulation (gndA) NADP-dependent phosphogluconate dehydrogenase [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
Flagella flhA 0.0000886 1 VF0430 Motility (flhA) flagellar biosynthesis protein FlhA [Flagella (VF0430) - Motility (VFC0204)] [Burkholderia pseudomallei K96243]
Lsp T2SS lspE 0.0000886 1 VF0154 Effector delivery system (lspE) general secretion pathway protein E [Lsp T2SS (VF0154) - Effector delivery system (VFC0086)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
FupA feoB 0.0000886 1 VF0550 Nutritional/Metabolic factor (feoB) Fe(2+) transporter permease subunit FeoB [FupA (VF0550) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
Flagella LPG_RS02380 0.0010631 8 VF0157 Motility (fleQ) transcriptional regulator FleQ [Flagella (VF0157) - Motility (VFC0204)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
Hsp60 htpB 0.0000886 1 VF0159 Adherence (htpB) Hsp60, 60K heat shock protein HtpB [Hsp60 (VF0159) - Adherence (VFC0001)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
Hap hap 0.0000886 1 VF0037 Adherence (hap) adhesion and penetration protein Hap [Hap (VF0037) - Adherence (VFC0001)] [Haemophilus influenzae N187]
TTSS secreted effectors CT_061 0.0000886 1 VF0711 Effector delivery system (CT_061) RNA polymerase sigma factor sigma-28 [TTSS secreted effectors (VF0711) - Effector delivery system (VFC0086)] [Chlamydia trachomatis D/UW-3/CX]
Purine biosynthesis purM 0.0000886 1 VF0559 Nutritional/Metabolic factor (purM) phosphoribosylaminoimidazole synthetase [Purine biosynthesis (VF0559) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
Pyrimidine biosynthesis carB 0.0163005 136 VF0558 Nutritional/Metabolic factor (carB) carbamoyl phosphate synthase large subunit [Pyrimidine biosynthesis (VF0558) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
PanC/PanD panD 0.0000886 1 VF0319 Nutritional/Metabolic factor (panD) aspartate 1-decarboxylase [PanC/PanD (VF0319) - Nutritional/Metabolic factor (VFC0272)] [Mycobacterium tuberculosis H37Rv]
InlK inlK 0.0000886 1 VF0439 Immune modulation (inlK) internalin K [InlK (VF0439) - Immune modulation (VFC0258)] [Listeria monocytogenes EGD-e]
FbpABC fbpC 0.0003544 4 VF0272 Nutritional/Metabolic factor (fbpC) iron(III) ABC transporter, ATP-binding protein [FbpABC (VF0272) - Nutritional/Metabolic factor (VFC0272)] [Neisseria meningitidis MC58]
PsaA psaA 0.0000886 1 VF0151 Nutritional/Metabolic factor (psaA) manganese ABC transporter, manganese-binding adhesion liprotein [PsaA (VF0151) - Nutritional/Metabolic factor (VFC0272)] [Streptococcus pneumoniae TIGR4]
CbpA/PspC cbpA/pspC 0.0000886 1 VF0150 Adherence (cbpA/pspC) choline binding protein A [CbpA/PspC (VF0150) - Adherence (VFC0001)] [Streptococcus pneumoniae TIGR4]
Flagella cheD 0.0004429 4 VF0394 Motility (flhA) flagellar biosynthesis protein FlhA [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081]
Flagella fleQ 0.0001772 2 VF0273 Motility (fleQ) transcriptional regulator FleQ [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1]
Cereulide cesC 0.0003544 4 VF0583 Exotoxin (cesC) ABC transporter ATP-binding protein, CesC [Cereulide (VF0583) - Exotoxin (VFC0235)] [Bacillus cereus AH187]
InlA inlA 0.0001772 2 VF0069 Invasion (inlA) Internalin A [InlA (VF0069) - Invasion (VFC0083)] [Listeria monocytogenes EGD-e]
Capsule galE 0.0000886 1 VF0465 Immune modulation (galE) UDP-glucose 4-epimerase GalE [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU]
TTSS cdsN 0.0009745 10 VF0344 Effector delivery system (cdsN) Type III secretion system ATPase [TTSS (VF0344) - Effector delivery system (VFC0086)] [Chlamydia trachomatis D/UW-3/CX]
Acinetobactin bauE 0.0002658 3 VF0467 Nutritional/Metabolic factor (bauE) ferric siderophore ABC transporter, ATP-binding protein BauE [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU]
MgtB mgtB 0.0008859 9 VF0106 Nutritional/Metabolic factor (mgtB) Mg2+ transport protein [MgtB (VF0106) - Nutritional/Metabolic factor (VFC0272)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
LplA1 lplA1 0.0000886 1 VF0347 Nutritional/Metabolic factor (lplA1) lipoate protein ligase [LplA1 (VF0347) - Nutritional/Metabolic factor (VFC0272)] [Listeria monocytogenes EGD-e]
SlpA slpA 0.0695429 768 VF0589 Adherence (slpA) cell surface protein (S-layer precursor protein) [SlpA (VF0589) - Adherence (VFC0001)] [Clostridium difficile 630]
FbpA fbpA 0.0001772 2 VF0349 Adherence (fbpA) fibronectin-binding protein [FbpA (VF0349) - Adherence (VFC0001)] [Listeria monocytogenes EGD-e]
EF-Tu tufA 2.6545889 11,281 VF0460 Adherence (tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4]
LPS kdtB 0.0000886 1 VF0056 Immune modulation (kdtB) lipopolysaccharide core biosynthesis protein [LPS (VF0056) - Immune modulation (VFC0258)] [Helicobacter pylori 26695]
Colibactin clbG 0.0000886 1 VF0573 Exotoxin (clbG) colibactin biosynthesis acyltransferase ClbG [Colibactin (VF0573) - Exotoxin (VFC0235)] [Klebsiella pneumoniae subsp. pneumoniae 1084]
MprAB mprA 0.0000886 1 VF0298 Regulation (mprA) two-component response regulator MrpA [MprAB (VF0298) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
T2SS gspE 0.0001772 2 VF0333 Effector delivery system (gspE) general secretion pathway protein E [T2SS (VF0333) - Effector delivery system (VFC0086)] [Shigella dysenteriae Sd197]
KatA katA 0.0003544 3 VF0454 Stress survival (katA) catalase [KatA (VF0454) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
MsrAB msrA/B(pilB 0.001506 15 VF0456 Stress survival (msrA/B(pilB)) trifunctional thioredoxin/methionine sulfoxide reductase A/B protein [MsrAB (VF0456) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
VAS T6SS vasH 0.0000886 1 VF0335 Effector delivery system (vasH) type VI secretion system regulatory protein VasH [VAS T6SS (VF0335) - Effector delivery system (VFC0086)] [Vibrio cholerae O1 biovar El Tor str. N16961]
CagA cagA 0.0000886 1 VF0059 Effector delivery system (cagA) cag T4SS translocated effector CagA [CagA (VF0059) - Effector delivery system (VFC0086)] [Helicobacter pylori 26695]
HSI-1 hsiG1/tssF 0.0000886 1 VF0334 Effector delivery system (hsiG1/tssF) type VI secretion system hcp secretion island protein HsiG1 [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
VPS vpsC 0.0001772 2 VF0615 Biofilm (vpsC) exopolysaccharide biosynthesis acetyltransferase VpsC [VPS (VF0615) - Biofilm (VFC0271)] [Vibrio cholerae O1 biovar El Tor str. N16961]
LPS rfbC 0.0001772 2 VF0171 Immune modulation (rfbC) dTDP-4-dehydrorhamnose 3,5-epimerase [LPS (VF0171) - Immune modulation (VFC0258)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
Flagella flhB 0.0000886 1 VF0051 Motility (flhB) flagellar biosynthesis protein [Flagella (VF0051) - Motility (VFC0204)] [Helicobacter pylori 26695]