Neisseria meningitidis

脑膜炎奈瑟氏球菌
Hazard Level
CDC Hazard Level Classification
Class III
Basic Information
Annotations on Species
<p style="text-indent: 2em;"><span style="color: rgb(44, 44, 54); background-color: rgb(255, 255, 255); font-size: 16px;">成对排列的球菌。细胞分裂在两个平面上发生,第二次分裂与第一次垂直。因此,在年轻、生长中的培养物(少于8小时)湿片中可以观察到短暂的四联体。初次分离通常在血琼脂、巧克力琼脂或Mueller–Hinton琼脂上进行。含有3–10% CO₂和高相对湿度的环境有助于生长。最适生长温度为36–37°C。菌落大小取决于培养基种类、拥挤程度和培养时间;在18–24小时后,菌落直径约为1.0 mm。菌落小、圆形、光滑、有光泽,有时呈粘液状且半透明(在Mueller–Hinton琼脂上),常带有虹彩。随着老化导致的自溶,菌落变得更为柔软且触摸时有橡胶感(接种针触碰可感知)。某些菌株在利用麦芽糖和葡萄糖产酸方面表现不稳定。</span></p><p style="text-indent: 2em;"><span style="color: rgb(44, 44, 54); background-color: rgb(255, 255, 255); font-size: 16px;">脑膜炎奈瑟菌是脑脊髓膜炎的病原体,常见于脑脊液中,也可作为败血症(包括Waterhouse–Friderichsen综合征)的病因存在于血液中,偶尔引起下生殖道感染(罕见)和肺炎(罕见)。可以从瘀点、关节、鼻咽部和结膜中分离培养,偶尔出现在性传播分泌物中。在无症状携带者的口腔或鼻咽部中常以共生状态存在。</span></p>
Phenotype
Morphology
Gram staining 阴性
Cell shape 球状
Cell length None
Cell width None
Spore formation 不产芽孢
Motility None
Gram staining
Cell shape
Cell length
Cell width
Spore formation
Motility
Colony size
Culture time
Hemolysis

Physiology
Oxygen requirement 微需氧
Growth temperature 36-37 °C
Optimal growth temperature 36-37 °C
Growth pH range None
Optimal growth pH None
Growth salt concentration (w/v) None
Optimal salt concentration (w/v) None
Colony description None
Temperature range
Temperature optimum
pH range
pH optimum
Salt concentration range
Salt concentration optimum
Oxygen requirement

Biochemistry
Catalase reaction None
Oxidase 阳性
V-P test None
Methyl red test None
Voges-Proskauer test
Methyl red test