|
Ent
|
fepA
|
0.0001422 |
1 |
VF0562
|
Nutritional/Metabolic factor |
(fepA) outer membrane receptor FepA [Ent (VF0562) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
OatA
|
oatA
|
0.0773606 |
543 |
VF0441
|
Immune modulation |
(oatA) peptidoglycan O-acetyltransferase [OatA (VF0441) - Immune modulation (VFC0258)] [Listeria monocytogenes EGD-e]
|
|
LPS
|
KP1_RS17240
|
0.0001422 |
1 |
VF0561
|
Immune modulation |
(KP1_RS17240) DUF4422 domain-containing protein [LPS (VF0561) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
LOS
|
rffG
|
3.9771047 |
7,032 |
VF0044
|
Immune modulation |
(licD) phosphocholine transferase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20]
|
|
TFP
|
pilT
|
0.0001422 |
1 |
VF1334
|
Adherence |
(pilT) type IV pilus twitching motility protein PilT [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU]
|
|
Lbp
|
lbpA
|
1.9881968 |
6,938 |
VF0047
|
Nutritional/Metabolic factor |
(lbpA) lactoferrin-binding protein A [Lbp (VF0047) - Nutritional/Metabolic factor (VFC0272)] [Neisseria meningitidis MC58]
|
|
LPS
|
gtrB
|
0.0001422 |
1 |
VF0124
|
Immune modulation |
(gtrB) bactoprenol glucosyl transferase [LPS (VF0124) - Immune modulation (VFC0258)] [Shigella flexneri 2a str. 301]
|
|
Capsule
|
cap8C
|
0.0001422 |
1 |
VF0003
|
Immune modulation |
(cap8C) type 8 capsular polysaccharide synthesis protein Cap8C [Capsule (VF0003) - Immune modulation (VFC0258)] [Staphylococcus aureus subsp. aureus MW2]
|
|
VirB type IV secretion system
|
virB11
|
0.0001422 |
1 |
VF0365
|
Effector delivery system |
(virB11) type IV secretion system protein ATPase VirB11 [VirB type IV secretion system (VF0365) - Effector delivery system (VFC0086)] [Brucella melitensis bv. 1 str. 16M]
|
|
Hyaluronic acid capsule
|
hasC
|
0.0022753 |
16 |
VF0244
|
Immune modulation |
(hasC) UTP--glucose-1-phosphate uridylyltransferase HasC [Hyaluronic acid capsule (VF0244) - Immune modulation (VFC0258)] [Streptococcus pyogenes M1 GAS]
|
|
Tbp
|
tbpB
|
1.8821104 |
7,020 |
VF0046
|
Nutritional/Metabolic factor |
(tbpB) transferrin-binding protein B [Tbp (VF0046) - Nutritional/Metabolic factor (VFC0272)] [Neisseria meningitidis MC58]
|
|
HpuAB
|
hpuA
|
1.524033 |
5,322 |
VF0049
|
Nutritional/Metabolic factor |
(hpuB) haemoglobin-haptoglobin-utilization protein [HpuAB (VF0049) - Nutritional/Metabolic factor (VFC0272)] [Neisseria meningitidis Z2491]
|
|
ESX-3
|
eccB3
|
0.0001422 |
1 |
VF0521
|
Effector delivery system |
(eccB3) Type VII secretion system protein EccB3 [ESX-3 (VF0521) - Effector delivery system (VFC0086)] [Mycobacterium tuberculosis H37Rv]
|
|
HmbR
|
hmbR
|
1.0476394 |
5,032 |
VF0048
|
Nutritional/Metabolic factor |
(hmbR) hemoglobin receptor [HmbR (VF0048) - Nutritional/Metabolic factor (VFC0272)] [Neisseria meningitidis MC58]
|
|
LPS
|
acpXL
|
0.9997156 |
7,025 |
VF0367
|
Immune modulation |
(acpXL) acyl carrier protein [LPS (VF0367) - Immune modulation (VFC0258)] [Brucella melitensis bv. 1 str. 16M]
|
|
SodB
|
sodB
|
1.0001422 |
7,018 |
VF0169
|
Stress survival |
(sodB) superoxide dismutase [SodB (VF0169) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
LOS
|
gmhA
|
0.0001422 |
1 |
VF0326
|
Immune modulation |
(gmhA) phosphoheptose isomerase [LOS (VF0326) - Immune modulation (VFC0258)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
|
|
AcrAB
|
acrA
|
0.0002844 |
1 |
VF0568
|
Antimicrobial activity/Competitive advantage |
(acrB) acriflavine resistance protein B [AcrAB (VF0568) - Antimicrobial activity/Competitive advantage (VFC0325)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Type VII secretion system
|
esaA
|
0.0004266 |
1 |
VF0403
|
Effector delivery system |
(esaA) type VII secretion system protein EsaA [Type VII secretion system (VF0403) - Effector delivery system (VFC0086)] [Staphylococcus aureus subsp. aureus MW2]
|
|
T2SS
|
gspE2
|
0.0001422 |
1 |
VF1335
|
Effector delivery system |
(gspE2) putative secretion pathway ATPase [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU]
|
|
Hemolysin
|
hlyB
|
0.0001422 |
1 |
VF0207
|
Exotoxin |
(hlyB) Hemolysin B [Hemolysin (VF0207) - Exotoxin (VFC0235)] [Escherichia coli O157:H7 str. EDL933]
|
|
T6SS
|
vipA/tssB
|
0.0008532 |
2 |
VF0569
|
Effector delivery system |
(vipB/tssC) type VI secretion system contractile sheath large subunit VipB [T6SS (VF0569) - Effector delivery system (VFC0086)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
AI-2
|
luxS
|
1.0012799 |
7,032 |
VF0406
|
Biofilm |
(luxS) S-ribosylhomocysteinase [AI-2 (VF0406) - Biofilm (VFC0271)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
Porin
|
porA
|
1.9854949 |
7,022 |
VF0081
|
Invasion |
(porA) porin PorA [Porin (VF0081) - Invasion (VFC0083)] [Neisseria meningitidis MC58]
|
|
IgA1 protease
|
iga
|
0.8647611 |
5,853 |
VF0080
|
Effector delivery system |
(iga) IgA-specific serine endopeptidase [IgA1 protease (VF0080) - Effector delivery system (VFC0086)] [Neisseria meningitidis MC58]
|
|
TTSS
|
popD
|
0.0001422 |
1 |
VF0083
|
Effector delivery system |
(popD) type III secretion system hydrophobic translocator, pore protein PopD [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
LPS
|
wbpA
|
0.0017065 |
12 |
VF0085
|
Immune modulation |
(wbpM) nucleotide sugar epimerase/dehydratase WbpM [LPS (VF0085) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1]
|
|
Capsule
|
ugd
|
0.0001422 |
1 |
VF0560
|
Immune modulation |
(ugd) UDP-glucose 6-dehydrogenase [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
LOS
|
rfaC
|
8.9559158 |
7,032 |
VF0078
|
Immune modulation |
(lgtE) glycosyltransferase family 25 protein [LOS (VF0078) - Immune modulation (VFC0258)] [Neisseria meningitidis MC58]
|
|
Opc
|
opc
|
0.6794653 |
4,565 |
VF0077
|
Invasion |
(opc) class 5 outer membrane protein [Opc (VF0077) - Invasion (VFC0083)] [Neisseria meningitidis MC58]
|
|
Polar flagella
|
nueA
|
1.000711 |
7,031 |
VF0473
|
Motility |
(nueA) NeuA protein [Polar flagella (VF0473) - Motility (VFC0204)] [Aeromonas hydrophila ML09-119]
|
|
LPS
|
bplL
|
0.0002844 |
2 |
VF0033
|
Immune modulation |
(bplL) lipopolysaccharide biosynthesis protein [LPS (VF0033) - Immune modulation (VFC0258)] [Bordetella pertussis Tohama I]
|
|
ESAT-6/CFP-10
|
esxA
|
0.0001422 |
1 |
VF0310
|
Effector delivery system |
(esxA) 6 kDa early secretory antigenic target EsxA (ESAT-6) [ESAT-6/CFP-10 (VF0310) - Effector delivery system (VFC0086)] [Mycobacterium tuberculosis H37Rv]
|
|
Capsule
|
siaB/synB
|
6.4918942 |
5,630 |
VF0079
|
Immune modulation |
(siaB/synB) polysialic acid capsule biosynthesis protein SiaB [Capsule (VF0079) - Immune modulation (VFC0258)] [Neisseria meningitidis MC58]
|
|
HMW1/HMW2
|
hmw1C
|
0.0002844 |
2 |
VF0038
|
Adherence |
(hmw1C) glycosyltransferase [HMW1/HMW2 (VF0038) - Adherence (VFC0001)] [Haemophilus influenzae str. 12]
|
|
Hsp60
|
htpB
|
1.0015643 |
7,032 |
VF0159
|
Adherence |
(htpB) Hsp60, 60K heat shock protein HtpB [Hsp60 (VF0159) - Adherence (VFC0001)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Hap
|
hap
|
0.0473549 |
330 |
VF0037
|
Adherence |
(hap) adhesion and penetration protein Hap [Hap (VF0037) - Adherence (VFC0001)] [Haemophilus influenzae N187]
|
|
K1 capsule
|
kpsU
|
0.0002844 |
2 |
VF0239
|
Invasion |
(kpsU) 3-deoxy-manno-octulosonate cytidylyltransferase [K1 capsule (VF0239) - Invasion (VFC0083)] [Escherichia coli O45:K1:H7 str. S88]
|
|
Pyrimidine biosynthesis
|
carB
|
0.0042662 |
27 |
VF0558
|
Nutritional/Metabolic factor |
(carB) carbamoyl phosphate synthase large subunit [Pyrimidine biosynthesis (VF0558) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
ClpC
|
clpC
|
0.0009954 |
7 |
VF0072
|
Stress survival |
(clpC) endopeptidase Clp ATP-binding chain C [ClpC (VF0072) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
|
|
ClpP
|
clpP
|
1.0009954 |
7,032 |
VF0074
|
Stress survival |
(clpP) ATP-dependent Clp protease proteolytic subunit [ClpP (VF0074) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
|
|
FbpABC
|
fbpC
|
3.0021331 |
7,022 |
VF0272
|
Nutritional/Metabolic factor |
(fbpC) iron(III) ABC transporter, ATP-binding protein [FbpABC (VF0272) - Nutritional/Metabolic factor (VFC0272)] [Neisseria meningitidis MC58]
|
|
Opa
|
opa
|
3.2731797 |
6,902 |
VF0076
|
Invasion |
(opa) outer membrane beta-barrel protein [Opa (VF0076) - Invasion (VFC0083)] [Neisseria meningitidis MC58]
|
|
Type IV pili
|
pilG
|
27.3710182 |
7,032 |
VF0075
|
Adherence |
(pilS) pilin [Type IV pili (VF0075) - Adherence (VFC0001)] [Neisseria meningitidis MC58]
|
|
Capsule
|
galE
|
0.0260239 |
183 |
VF0465
|
Immune modulation |
(ACICU_RS00475) sugar transferase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU]
|
|
LPS
|
wbtL
|
1.3253697 |
7,022 |
VF0542
|
Immune modulation |
(wbtL) glucose-1-phosphate thymidylyltransferase [LPS (VF0542) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
Alpha-Hemolysin
|
hlyB
|
1.0651308 |
6,662 |
VF0225
|
Exotoxin |
(hlyB) Hemolysin B [Alpha-Hemolysin (VF0225) - Exotoxin (VFC0235)] [Escherichia coli CFT073]
|
|
Capsule
|
rpe
|
0.0012799 |
9 |
VF0543
|
Immune modulation |
(rpe) ribulose-phosphate 3-epimerase [Capsule (VF0543) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
SodA
|
sodA
|
0.0001422 |
1 |
VF0304
|
Stress survival |
(sodA) superoxide dismutase [SodA (VF0304) - Stress survival (VFC0282)] [Mycobacterium tuberculosis H37Rv]
|
|
P97/P102 paralog family
|
p97
|
0.0001422 |
1 |
VF0426
|
Adherence |
(p97) protein p97; cilium adhesin [P97/P102 paralog family (VF0426) - Adherence (VFC0001)] [Mycoplasma hyopneumoniae 232]
|
|
HSI-2
|
PA1665
|
0.0002844 |
1 |
VF0943
|
Effector delivery system |
(PA1665) hypothetical protein [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
PDIM
|
Rv2952
|
0.0002844 |
2 |
VF0309
|
Immune modulation |
(Rv2952) phthiotriol/phenolphthiotriol dimycocerosates methyltransferase [PDIM (VF0309) - Immune modulation (VFC0258)] [Mycobacterium tuberculosis H37Rv]
|
|
EF-Tu
|
tufA
|
2.3410125 |
7,029 |
VF0460
|
Adherence |
(tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
FHbp
|
fHbp
|
1.0063993 |
7,009 |
VF0452
|
Immune modulation |
(fHbp) factor H binding protein [FHbp (VF0452) - Immune modulation (VFC0258)] [Neisseria meningitidis MC58]
|
|
LPS
|
gluP
|
0.000711 |
5 |
VF0056
|
Immune modulation |
(kdtB) lipopolysaccharide core biosynthesis protein [LPS (VF0056) - Immune modulation (VFC0258)] [Helicobacter pylori 26695]
|
|
MtrCDE
|
mtrE
|
3.0193402 |
7,028 |
VF0451
|
Antimicrobial activity/Competitive advantage |
(mtrC) membrane fusion protein MtrC [MtrCDE (VF0451) - Antimicrobial activity/Competitive advantage (VFC0325)] [Neisseria meningitidis MC58]
|
|
T4SS secreted effectors
|
CBU_1566
|
0.0011377 |
8 |
VF0696
|
Effector delivery system |
(CBU_1566) Coxiella Dot/Icm type IVB secretion system translocated effector [T4SS secreted effectors (VF0696) - Effector delivery system (VFC0086)] [Coxiella burnetii RSA 493]
|
|
KatA
|
katA
|
1.0092435 |
7,030 |
VF0454
|
Stress survival |
(katA) catalase [KatA (VF0454) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
|
|
NspA
|
nspA
|
0.9985779 |
7,017 |
VF0453
|
Immune modulation |
(nspA) neisserial surface protein A [NspA (VF0453) - Immune modulation (VFC0258)] [Neisseria meningitidis MC58]
|
|
MsrAB
|
msrA/B(pilB
|
1.0015643 |
7,032 |
VF0456
|
Stress survival |
(msrA/B(pilB)) trifunctional thioredoxin/methionine sulfoxide reductase A/B protein [MsrAB (VF0456) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
|
|
HSI-1
|
ppkA
|
0.0012799 |
7 |
VF0334
|
Effector delivery system |
(pppA) Pseudomonas protein phosphatase PppA [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
Isd
|
isdB
|
0.0002844 |
1 |
VF0015
|
Nutritional/Metabolic factor |
(isdF) iron-regulated surface determinant protein F, ATP-binding-cassette-type transmembrane transporter [Isd (VF0015) - Nutritional/Metabolic factor (VFC0272)] [Staphylococcus aureus subsp. aureus str. Newman]
|
|
SigA
|
sigA/rpoV
|
0.0001422 |
1 |
VF0257
|
Regulation |
(sigA/rpoV) RNA polymerase sigma factor SigA [SigA (VF0257) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
Yersiniabactin
|
ybtQ
|
0.0001422 |
1 |
VF0136
|
Nutritional/Metabolic factor |
(ybtQ) yersiniabactin ABC transporter ATP-binding/permease protein YbtQ [Yersiniabactin (VF0136) - Nutritional/Metabolic factor (VFC0272)] [Yersinia pestis CO92]
|
|
MntABC
|
mntC
|
3.0017065 |
7,030 |
VF0455
|
Stress survival |
(mntB) Manganese transport system membrane protein MntB [MntABC (VF0455) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
|
|
SCI (Salmonella centrisome island)/SPI-6 T6SS
|
STM0274
|
0.0008532 |
6 |
VF0974
|
Effector delivery system |
|
|
RecN
|
recN
|
1.0009954 |
7,032 |
VF0457
|
Stress survival |
(recN) DNA repair protein RecN [RecN (VF0457) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
|
|
RTX protein
|
frpA
|
3.9773891 |
7,020 |
VF0897
|
Adherence |
(frpA) iron-regulated protein FrpA [RTX protein (VF0897) - Adherence (VFC0001)] [Neisseria meningitidis MC58]
|
|
Eps T2SS
|
epsI
|
0.0002844 |
1 |
VF0613
|
Effector delivery system |
(epsI) type II secretion system minor pseudopilin GspI [Eps T2SS (VF0613) - Effector delivery system (VFC0086)] [Vibrio cholerae O395]
|
|
VPS
|
vpsP
|
0.0001422 |
1 |
VF0615
|
Biofilm |
(vpsP) exopolysaccharide biosynthesis protein VpsP [VPS (VF0615) - Biofilm (VFC0271)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
Alginate
|
mucP
|
0.0024175 |
15 |
VF0091
|
Biofilm |
(algC) phosphomannomutase AlgC [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1]
|
|
Urease
|
ureB
|
0.0002844 |
2 |
VF0050
|
Stress survival |
(ureB) urease beta subunit UreB, urea amidohydrolase [Urease (VF0050) - Stress survival (VFC0282)] [Helicobacter pylori 26695]
|
|
Pyoverdine
|
pvdI
|
0.0001422 |
1 |
VF0094
|
Nutritional/Metabolic factor |
(pvdI) peptide synthase [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1]
|
|
LPS
|
rfbC
|
0.4078498 |
2,458 |
VF0171
|
Immune modulation |
(rfbC) dTDP-4-dehydrorhamnose 3,5-epimerase [LPS (VF0171) - Immune modulation (VFC0258)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
FarAB
|
farB
|
2.0113766 |
7,026 |
VF0450
|
Antimicrobial activity/Competitive advantage |
(farA) fatty acid efflux system protein FarA [FarAB (VF0450) - Antimicrobial activity/Competitive advantage (VFC0325)] [Neisseria meningitidis MC58]
|