|
Ata
|
ata
|
0.0001226 |
11 |
VF1333
|
Adherence |
(ata) trimeric autotransporter adhesin Ata [Ata (VF1333) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU]
|
|
IcsP (SopA)
|
icsP/sopA
|
0.0243137 |
3,310 |
VF0122
|
Exoenzyme |
(icsP/sopA) outer membrane protease of the OmpP family, involved in cleavage of surface exposed IcsA [IcsP (SopA) (VF0122) - Exoenzyme (VFC0251)] [Shigella flexneri 2a str. 301]
|
|
FBPs
|
prtF2
|
0.0001009 |
4 |
VF0243
|
Adherence |
(sfbII/sof) serum opacification factor [FBPs (VF0243) - Adherence (VFC0001)] [Streptococcus pyogenes MGAS6180]
|
|
Alpha-hemolysin
|
hly/hla
|
0.0000433 |
6 |
VF0001
|
Exotoxin |
(hly/hla) Alpha-Hemolysin precursor [Alpha-hemolysin (VF0001) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus MW2]
|
|
IcsA (VirG)
|
icsA/virG
|
0.0146805 |
2,014 |
VF0121
|
Motility |
(icsA/virG) autotransporter, actin tail assembly protein IcsA/VirG [IcsA (VirG) (VF0121) - Motility (VFC0204)] [Shigella flexneri 2a str. 301]
|
|
TFP
|
ACICU_RS16840
|
0.0008364 |
53 |
VF1334
|
Adherence |
(pilS) PAS domain-containing sensor histidine kinase [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU]
|
|
M protein
|
emm
|
0.0000072 |
1 |
VF0242
|
Immune modulation |
(emm) M protein [M protein (VF0242) - Immune modulation (VFC0258)] [Streptococcus pyogenes M1 GAS]
|
|
LPS
|
gtr
|
0.1046601 |
9,632 |
VF0124
|
Immune modulation |
(gtr) glucosyl tranferase [LPS (VF0124) - Immune modulation (VFC0258)] [Shigella flexneri 2a str. 301]
|
|
Capsule
|
cap8F
|
0.1417725 |
19,387 |
VF0003
|
Immune modulation |
(cap8J) type 8 capsular polysaccharide synthesis protein Cap8J [Capsule (VF0003) - Immune modulation (VFC0258)] [Staphylococcus aureus subsp. aureus MW2]
|
|
CbetaG
|
cgs
|
0.0000721 |
8 |
VF0366
|
Immune modulation |
(cgs) cyclic beta 1-2 glucan synthetase [CbetaG (VF0366) - Immune modulation (VFC0258)] [Brucella melitensis bv. 1 str. 16M]
|
|
Rvh T4SS
|
virB11
|
0.0000072 |
1 |
VF0487
|
Effector delivery system |
(virB11) type IV secretion system ATPase VirB11 [Rvh T4SS (VF0487) - Effector delivery system (VFC0086)] [Anaplasma phagocytophilum HZ]
|
|
C5a peptidase
|
scpA/scpB
|
0.0000072 |
1 |
VF0245
|
Adherence |
(scpA/scpB) streptococcal C5a peptidase [C5a peptidase (VF0245) - Adherence (VFC0001)] [Streptococcus pyogenes M1 GAS]
|
|
Aerobactin
|
iutA
|
0.5761679 |
35,960 |
VF0123
|
Nutritional/Metabolic factor |
(iucC) aerobactin synthesis protein IucC [Aerobactin (VF0123) - Nutritional/Metabolic factor (VFC0272)] [Shigella flexneri 2a str. 301]
|
|
Hyaluronic acid capsule
|
hasA
|
0.0001514 |
16 |
VF0244
|
Immune modulation |
(hasB) UDP-glucose 6-dehydrogenase HasB [Hyaluronic acid capsule (VF0244) - Immune modulation (VFC0258)] [Streptococcus pyogenes M1 GAS]
|
|
Beta-hemolysin
|
hlb
|
0.0000433 |
5 |
VF0002
|
Exotoxin |
(hlb) beta-hemolysin [Beta-hemolysin (VF0002) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus COL]
|
|
Type I pili
|
fimD
|
0.0002812 |
35 |
VF0486
|
Adherence |
(fimC) outer membrane usher protein [Type I pili (VF0486) - Adherence (VFC0001)] [Aeromonas hydrophila ML09-119]
|
|
VirB type IV secretion system
|
virB3
|
0.0001082 |
6 |
VF0365
|
Effector delivery system |
(virB3) type IV secretion system protein VirB3 [VirB type IV secretion system (VF0365) - Effector delivery system (VFC0086)] [Brucella melitensis bv. 1 str. 16M]
|
|
Streptokinase
|
ska
|
0.0000505 |
4 |
VF0247
|
Exoenzyme |
(ska) streptokinase A precursor [Streptokinase (VF0247) - Exoenzyme (VFC0251)] [Streptococcus pyogenes M1 GAS]
|
|
T6SS
|
vgrG/tssI
|
0.0007138 |
48 |
VF1337
|
Effector delivery system |
(tssC) type VI secretion system contractile sheath large subunit [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU]
|
|
TCP
|
tcpI
|
0.0000361 |
5 |
VF0126
|
Adherence |
(tcpI) negative regulator of the major pilin TcpA [TCP (VF0126) - Adherence (VFC0001)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
BvrR-BvrS
|
bvrR
|
0.0000793 |
10 |
VF0368
|
Regulation |
(bvrR) response regulator transcription factor [BvrR-BvrS (VF0368) - Regulation (VFC0301)] [Brucella melitensis bv. 1 str. 16M]
|
|
CNA
|
cna
|
0.0001154 |
14 |
VF0005
|
Adherence |
(cna) collagen adhesin precursor [CNA (VF0005) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
|
|
LPS
|
wbpZ
|
1.0025597 |
138,541 |
VF0367
|
Immune modulation |
(manCcore) mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase [LPS (VF0367) - Immune modulation (VFC0258)] [Brucella melitensis bv. 1 str. 16M]
|
|
Clumping factor
|
clfA
|
0.0001803 |
23 |
VF0004
|
Adherence |
(clfB) Clumping factor B, adhesin [Clumping factor (VF0004) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
|
|
T6SS secreted effectors
|
tse4
|
0.0000216 |
3 |
VF1338
|
Effector delivery system |
(tse3) T6SS effector Tse3, unknown function [T6SS secreted effectors (VF1338) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ATCC 17978]
|
|
Hyaluronidase
|
hylA
|
0.0000361 |
1 |
VF0246
|
Exoenzyme |
(hylA) hyaluronidase [Hyaluronidase (VF0246) - Exoenzyme (VFC0251)] [Streptococcus pyogenes M1 GAS]
|
|
CT
|
ctxA
|
0.0009734 |
135 |
VF0128
|
Exotoxin |
(ctxB) cholera enterotoxin, B subunit [CT (VF0128) - Exotoxin (VFC0235)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
T2SS
|
gspD
|
0.0003028 |
27 |
VF1335
|
Effector delivery system |
(gspN) type II secretion system protein N [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU]
|
|
SpeB
|
speB
|
0.0000072 |
1 |
VF0249
|
Exoenzyme |
(speB) pyrogenic exotoxin B [SpeB (VF0249) - Exoenzyme (VFC0251)] [Streptococcus pyogenes M1 GAS]
|
|
Delta-hemolysin
|
hld
|
0.0000072 |
1 |
VF0007
|
Exotoxin |
(hld) delta-hemolysin [Delta-hemolysin (VF0007) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus MW2]
|
|
ACF
|
acfD
|
0.001096 |
135 |
VF0127
|
Others |
(acfD) accessory colonization factor AcfD [ACF (VF0127) - Others (VFC0346)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
Staphopain
|
sspB
|
0.0000649 |
7 |
VF0006
|
Exoenzyme |
(sspB) staphopain cysteine proteinase SspB [Staphopain (VF0006) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus MW2]
|
|
VirB/VirD4 type IV secretion system
|
virB4
|
0.0001298 |
18 |
VF0369
|
Effector delivery system |
(virB11) type IV secretion system virB11 protein homolog [VirB/VirD4 type IV secretion system (VF0369) - Effector delivery system (VFC0086)] [Bartonella henselae str. Houston-1]
|
|
Spes
|
speH
|
0.0000288 |
1 |
VF0248
|
Exotoxin |
(speH) streptococcal exotoxin H precursor [Spes (VF0248) - Exotoxin (VFC0235)] [Streptococcus pyogenes M1 GAS]
|
|
EbpS
|
ebp
|
0.0001298 |
17 |
VF0008
|
Adherence |
(ebp) cell surface elastin binding protein [EbpS (VF0008) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Fsr
|
fsrB
|
0.0000072 |
1 |
VF0360
|
Biofilm |
(fsrB) agrBfs protein [Fsr (VF0360) - Biofilm (VFC0271)] [Enterococcus faecalis V583]
|
|
T6SS
|
AHA_RS09305
|
1.3276443 |
95,763 |
VF0480
|
Effector delivery system |
(hcp1) HcpA-like protein [T6SS (VF0480) - Effector delivery system (VFC0086)] [Aeromonas hydrophila subsp. hydrophila ATCC 7966]
|
|
Pic
|
pic
|
0.0141902 |
1,775 |
VF0120
|
Exoenzyme |
(pic) serine protease, autotransporter Pic [Pic (VF0120) - Exoenzyme (VFC0251)] [Shigella flexneri 2a str. 301]
|
|
TraJ
|
AAA92657
|
0.2078061 |
28,156 |
VF0241
|
Invasion |
(AAA92657) unknown protein [TraJ (VF0241) - Invasion (VFC0083)] [Escherichia coli]
|
|
BopD
|
bopD
|
0.0000649 |
7 |
VF0362
|
Biofilm |
(bopD) sugar-binding transcriptional regulator, LacI family [BopD (VF0362) - Biofilm (VFC0271)] [Enterococcus faecalis V583]
|
|
Capsule
|
cpsD
|
0.0023795 |
323 |
VF0361
|
Immune modulation |
(cpsB/cdsA) phosphatidate cytidylyltransferase [Capsule (VF0361) - Immune modulation (VFC0258)] [Enterococcus faecalis V583]
|
|
CNF-1
|
cnf1
|
0.0026895 |
328 |
VF0240
|
Exotoxin |
(cnf1) cytotoxic necrotizing factor 1 [CNF-1 (VF0240) - Exotoxin (VFC0235)] [Escherichia coli str. E-B35]
|
|
RtxA
|
rtxH
|
0.0000433 |
6 |
VF0482
|
Exotoxin |
(rtxA) multifunctional autoprocessing repeats-in-toxins (MARTX) toxin [RtxA (VF0482) - Exotoxin (VFC0235)] [Aeromonas hydrophila subsp. hydrophila ATCC 7966]
|
|
Lateral flagella
|
lfhA
|
0.1751065 |
23,451 |
VF0474
|
Motility |
(lafK) two-component system lateral flagellar response regulator [Lateral flagella (VF0474) - Motility (VFC0204)] [Aeromonas salmonicida subsp. salmonicida A449]
|
|
PhoPQ
|
phoP
|
2.0037927 |
138,595 |
VF0111
|
Regulation |
(phoP) response regulator in two-component regulatory system with PhoQ [PhoPQ (VF0111) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Pic
|
pic
|
0.0526005 |
6,621 |
VF0232
|
Effector delivery system |
(pic) Pic serine protease precursor, autotransporter [Pic (VF0232) - Effector delivery system (VFC0086)] [Escherichia coli CFT073]
|
|
Esp
|
esp
|
0.0000361 |
4 |
VF0353
|
Adherence |
(esp) Enterococcal surface protein; Esp [Esp (VF0353) - Adherence (VFC0001)] [Enterococcus faecalis str. MMH594]
|
|
FbpA/Fbp68
|
fbpA/fbp68
|
0.0000144 |
2 |
VF0595
|
Adherence |
(fbpA/fbp68) fibronectin-binding protein FbpA [FbpA/Fbp68 (VF0595) - Adherence (VFC0001)] [Clostridium difficile 630]
|
|
Polar flagella
|
pomB2
|
2.0026895 |
138,648 |
VF0473
|
Motility |
(fliI) flagellum-specific ATP synthase [Polar flagella (VF0473) - Motility (VFC0204)] [Aeromonas hydrophila ML09-119]
|
|
GroEL
|
groEL
|
0.0008364 |
108 |
VF0594
|
Adherence |
(groEL) chaperonin GroEL [GroEL (VF0594) - Adherence (VFC0001)] [Clostridium difficile 630]
|
|
AS
|
prgB/asc10
|
0.0000721 |
4 |
VF0352
|
Adherence |
(EF0149) aggregation substance [AS (VF0352) - Adherence (VFC0001)] [Enterococcus faecalis V583]
|
|
Sat
|
sat
|
0.1528334 |
17,462 |
VF0231
|
Effector delivery system |
(sat) Aecreted auto transpoter toxin [Sat (VF0231) - Effector delivery system (VFC0086)] [Escherichia coli CFT073]
|
|
Fur
|
fur
|
1.0002235 |
138,608 |
VF0113
|
Regulation |
(fur) ferric iron uptake transcriptional regulator [Fur (VF0113) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Chu
|
chuX
|
1.1704558 |
34,245 |
VF0234
|
Nutritional/Metabolic factor |
(chuY) ChuY [Chu (VF0234) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli O157:H7 str. EDL933]
|
|
Ace
|
ace
|
0.0000216 |
3 |
VF0355
|
Adherence |
(ace) collagen adhesin protein [Ace (VF0355) - Adherence (VFC0001)] [Enterococcus faecalis V583]
|
|
Tsh
|
tsh
|
0.0913784 |
12,345 |
VF0233
|
Effector delivery system |
(tsh) temperature-sensitive protein Tsh [Tsh (VF0233) - Effector delivery system (VFC0086)] [Escherichia coli O25b:H4-ST131]
|
|
RpoS
|
rpoS
|
1.0192808 |
138,470 |
VF0112
|
Regulation |
(rpoS) RNA polymerase sigma factor RpoS [RpoS (VF0112) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Tap type IV pili
|
tapU
|
0.0001586 |
20 |
VF0475
|
Adherence |
(tapB) type IV pilus assembly ATPase, PilB-like [Tap type IV pili (VF0475) - Adherence (VFC0001)] [Aeromonas hydrophila ML09-119]
|
|
Exe T2SS
|
exeJ
|
0.8032115 |
71,732 |
VF0478
|
Effector delivery system |
(exeD) general secretion pathway protein D [Exe T2SS (VF0478) - Effector delivery system (VFC0086)] [Aeromonas hydrophila ML09-119]
|
|
OmpA
|
ompA
|
1.0015575 |
138,615 |
VF0236
|
Invasion |
(ompA) outer membrane protein A [OmpA (VF0236) - Invasion (VFC0083)] [Escherichia coli O18:K1:H7 str. RS218]
|
|
CDT
|
cdtA
|
0.0000288 |
3 |
VF0115
|
Exotoxin |
(cdtB) cytolethal distending toxin B [CDT (VF0115) - Exotoxin (VFC0235)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
|
|
Gelatinase
|
gelE
|
0.0000144 |
2 |
VF0357
|
Exoenzyme |
(gelE) coccolysin [Gelatinase (VF0357) - Exoenzyme (VFC0251)] [Enterococcus faecalis V583]
|
|
S fimbriae
|
sfaG
|
0.0059414 |
801 |
VF0235
|
Adherence |
(sfaH) S fimbriae adhesin SfaH [S fimbriae (VF0235) - Adherence (VFC0001)] [Escherichia coli O18:K1:H7 str. IHE3034]
|
|
Flagella
|
pseA
|
0.0010095 |
36 |
VF0114
|
Motility |
(motB) flagellar motor protein MotB [Flagella (VF0114) - Motility (VFC0204)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
|
|
CD2831
|
CD2831
|
0.0000072 |
1 |
VF0598
|
Adherence |
(CD2831) SrtB-anchored collagen-binding adhesin [CD2831 (VF0598) - Adherence (VFC0001)] [Clostridium difficile 630]
|
|
Cytolysin
|
cylB
|
0.0000649 |
1 |
VF0356
|
Exotoxin |
(cylI) cytolysin immunity protein [Cytolysin (VF0356) - Exotoxin (VFC0235)] [Enterococcus faecalis str. MMH594]
|
|
Shiga toxin
|
stxA
|
0.8875381 |
31,424 |
VF0117
|
Exotoxin |
(stxB) Shiga toxin subunit B precursor [Shiga toxin (VF0117) - Exotoxin (VFC0235)] [Shigella dysenteriae Sd197]
|
|
AslA
|
aslA
|
0.9925444 |
137,255 |
VF0238
|
Invasion |
(aslA) putative arylsulfatase [AslA (VF0238) - Invasion (VFC0083)] [Escherichia coli O18:K1:H7 str. RS218]
|
|
Hyaluronidase
|
EF3023
|
0.0000865 |
8 |
VF0359
|
Exoenzyme |
(EF0818) polysaccharide lyase, family 8 [Hyaluronidase (VF0359) - Exoenzyme (VFC0251)] [Enterococcus faecalis V583]
|
|
TTSS (SPI-1 encode)
|
invB
|
2.2329562 |
97,502 |
VF0116
|
Effector delivery system |
(sipC/sspC) type III secretion system hydrophilic translocator, pore protein SipC [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Ibes
|
ibeC
|
2.4565677 |
138,657 |
VF0237
|
Invasion |
(ibeB) Cu(+)/Ag(+) efflux RND transporter outer membrane channel CusC [Ibes (VF0237) - Invasion (VFC0083)] [Escherichia coli O45:K1:H7 str. S88]
|
|
T3SS
|
ascN
|
0.0000144 |
2 |
VF0479
|
Effector delivery system |
(exsA) Type III secretion system transcriptional regulator [T3SS (VF0479) - Effector delivery system (VFC0086)] [Aeromonas salmonicida subsp. salmonicida A449]
|
|
SprE
|
sprE
|
0.0000072 |
1 |
VF0358
|
Exoenzyme |
(sprE) serine proteinase, V8 family [SprE (VF0358) - Exoenzyme (VFC0251)] [Enterococcus faecalis V583]
|
|
SigA
|
sigA
|
0.024732 |
3,315 |
VF0119
|
Exoenzyme |
(sigA) serine protease, autotransporter SigA [SigA (VF0119) - Exoenzyme (VFC0251)] [Shigella flexneri 2a str. 301]
|
|
K1 capsule
|
kpsD
|
2.3701645 |
40,874 |
VF0239
|
Invasion |
(kpsD) Polysialic acid transport protein precursor [K1 capsule (VF0239) - Invasion (VFC0083)] [Escherichia coli O45:K1:H7 str. S88]
|
|
TTSS
|
spa15
|
0.4283747 |
4,044 |
VF0118
|
Effector delivery system |
(ipgE) type III secretion system chaperone for IpgD [TTSS (VF0118) - Effector delivery system (VFC0086)] [Shigella flexneri 2a str. 301]
|
|
Phospholipase C
|
plc1
|
0.0001154 |
11 |
VF0470
|
Exotoxin |
(plc2) phospholipase C [Phospholipase C (VF0470) - Exotoxin (VFC0235)] [Acinetobacter baumannii ACICU]
|
|
Salmochelin siderophore
|
iroN
|
1.1250009 |
59,967 |
VF0230
|
Nutritional/Metabolic factor |
(iroB) glucosyltransferase IroB [Salmochelin siderophore (VF0230) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073]
|
|
PNAG
|
pgaB
|
0.0026967 |
360 |
VF0472
|
Biofilm |
(pgaD) poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD [PNAG (VF0472) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU]
|
|
BSH
|
bsh
|
0.0000505 |
7 |
VF0350
|
Stress survival |
(bsh) bile salt hydrolase [BSH (VF0350) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
|
|
Quorom sensing
|
abaI
|
0.0000216 |
2 |
VF0471
|
Biofilm |
(abaI) N-acyl-L-homoserine lactone synthetase [Quorom sensing (VF0471) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU]
|
|
Capsule
|
cps4L
|
0.0028842 |
370 |
VF0144
|
Immune modulation |
(cps4I) capsular polysaccharide biosynthesis protein Cps4I [Capsule (VF0144) - Immune modulation (VFC0258)] [Streptococcus pneumoniae TIGR4]
|
|
V8 protease
|
sspA
|
0.0000433 |
6 |
VF0023
|
Exoenzyme |
(sspA) serine protease; V8 protease; glutamyl endopeptidase [V8 protease (VF0023) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus MW2]
|
|
MARTX
|
rtxB
|
0.0001154 |
15 |
VF0265
|
Exotoxin |
(rtxA) RTX toxin RtxA [MARTX (VF0265) - Exotoxin (VFC0235)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
PmrAB
|
pmrA
|
1.9991275 |
138,364 |
VF1355
|
Regulation |
(pmrB) sensory kinase PmrB [PmrAB (VF1355) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Autolysin
|
lytA
|
0.0000144 |
2 |
VF0143
|
Exoenzyme |
(lytA) autolysin (N-acetylmuramoyl-L-alanine amidase) [Autolysin (VF0143) - Exoenzyme (VFC0251)] [Streptococcus pneumoniae TIGR4]
|
|
Hpt
|
hpt
|
0.0000072 |
1 |
VF0264
|
Nutritional/Metabolic factor |
(hpt) hexose phosphate transport protein [Hpt (VF0264) - Nutritional/Metabolic factor (VFC0272)] [Listeria monocytogenes EGD-e]
|
|
TTSS secreted effectors
|
espM2
|
4.0146805 |
114,735 |
VF1111
|
Effector delivery system |
(nleG2-2) DUF1076 domain-containing protein [TTSS secreted effectors (VF1111) - Effector delivery system (VFC0086)] [Escherichia coli O55:H7 str. CB9615]
|
|
Kappa-toxin
|
colA
|
0.0000361 |
3 |
VF0388
|
Exoenzyme |
(colA) collagenase [Kappa-toxin (VF0388) - Exoenzyme (VFC0251)] [Clostridium perfringens str. 13]
|
|
Hyaluronidase
|
hysA
|
0.0000072 |
1 |
VF0146
|
Exoenzyme |
(hysA) hyaluronidase [Hyaluronidase (VF0146) - Exoenzyme (VFC0251)] [Streptococcus pneumoniae TIGR4]
|
|
Vat
|
vat
|
0.208008 |
18,774 |
VF1112
|
Effector delivery system |
(vat) vacuolating autotransporter toxin [Vat (VF1112) - Effector delivery system (VFC0086)] [Escherichia coli CFT073]
|
|
Aureolysin
|
aur
|
0.0001226 |
16 |
VF0024
|
Exoenzyme |
(aur) zinc metalloproteinase aureolysin [Aureolysin (VF0024) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Neuraminidase
|
nanB
|
0.0000072 |
1 |
VF0148
|
Exoenzyme |
(nanB) neuraminidase B [Neuraminidase (VF0148) - Exoenzyme (VFC0251)] [Streptococcus pneumoniae TIGR4]
|
|
HitABC
|
hitC
|
0.0000505 |
7 |
VF0268
|
Nutritional/Metabolic factor |
(hitC) iron(III) ABC transporter, ATP-binding protein [HitABC (VF0268) - Nutritional/Metabolic factor (VFC0272)] [Haemophilus influenzae Rd KW20]
|
|
IgA1 protease
|
iga
|
0.0000216 |
3 |
VF0147
|
Immune modulation |
(iga) G5 domain-containing protein [IgA1 protease (VF0147) - Immune modulation (VFC0258)] [Streptococcus pneumoniae TIGR4]
|
|
Mu-toxin
|
nagH
|
0.0000072 |
1 |
VF0389
|
Exoenzyme |
(nagH) hyaluronidase [Mu-toxin (VF0389) - Exoenzyme (VFC0251)] [Clostridium perfringens str. 13]
|
|
Cya
|
cyaB
|
0.0000216 |
3 |
VF0028
|
Exotoxin |
(cyaB) cyclolysin secretion ATP-binding protein [Cya (VF0028) - Exotoxin (VFC0235)] [Bordetella pertussis Tohama I]
|
|
Pneumolysin
|
ply
|
0.0000072 |
1 |
VF0149
|
Exotoxin |
(ply) pneumolysin [Pneumolysin (VF0149) - Exotoxin (VFC0235)] [Streptococcus pneumoniae TIGR4]
|
|
CsrA
|
csrA
|
1.000584 |
138,570 |
VF0261
|
Regulation |
(csrA) carbon storage regulator CsrA [CsrA (VF0261) - Regulation (VFC0301)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
TTSS
|
yscT
|
0.0000793 |
8 |
VF0140
|
Effector delivery system |
(yscP) type III secretion system needle length regulator [TTSS (VF0140) - Effector delivery system (VFC0086)] [Yersinia pestis CO92]
|
|
Theta-toxin/PFO
|
pfoA
|
0.0000072 |
1 |
VF0382
|
Exotoxin |
(pfoA) perfringolysin O [Theta-toxin/PFO (VF0382) - Exotoxin (VFC0235)] [Clostridium perfringens str. 13]
|
|
TTSS secreted effectors
|
espO1-2
|
14.5448095 |
138,362 |
VF1110
|
Effector delivery system |
(nleE) Type III secretion system effector NleE [TTSS secreted effectors (VF1110) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933]
|
|
RelA
|
relA
|
0.0000288 |
4 |
VF0260
|
Regulation |
(relA) GTP diphosphokinase [RelA (VF0260) - Regulation (VFC0301)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
SvpA
|
hbp2
|
0.0000216 |
2 |
VF0263
|
Nutritional/Metabolic factor |
(hbp2) hypothetical protein [SvpA (VF0263) - Nutritional/Metabolic factor (VFC0272)] [Listeria monocytogenes EGD-e]
|
|
LetA/S
|
letA
|
0.0007138 |
99 |
VF0262
|
Regulation |
(letA) UvrY/SirA/GacA family response regulator transcription factor [LetA/S (VF0262) - Regulation (VFC0301)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
SE
|
sec
|
0.0000577 |
5 |
VF0020
|
Exotoxin |
(selk) staphylococcal enterotoxin K precursor [SE (VF0020) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Capsule
|
capB
|
0.0000433 |
6 |
VF0141
|
Immune modulation |
(capB) CapB, involved in Poly-gamma-glutamate synthesis [Capsule (VF0141) - Immune modulation (VFC0258)] [Bacillus anthracis]
|
|
HSI-3 T6SS secreted effectors
|
pldB/tle5b
|
0.0000361 |
4 |
VF1350
|
Effector delivery system |
(pldB/tle5b) phospholipase D [HSI-3 T6SS secreted effectors (VF1350) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
YadA
|
yadA
|
0.0000937 |
13 |
VF0133
|
Effector delivery system |
(yadA) trimeric autotransporter adhesin YadA [YadA (VF0133) - Effector delivery system (VFC0086)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
Lipase
|
lip
|
0.0002091 |
24 |
VF0012
|
Exoenzyme |
(lip) triacylglycerol lipase precursor [Lipase (VF0012) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus MW2]
|
|
BoNT
|
bont
|
0.0000072 |
1 |
VF0375
|
Exotoxin |
(bont) botulinum neurotoxin, BoNT [BoNT (VF0375) - Exotoxin (VFC0235)] [Clostridium botulinum B1 str. Okra]
|
|
GRAB
|
grab
|
0.0000144 |
1 |
VF0254
|
Others |
(grab) protein GRAB (protein G-related alpha 2M-binding protein) [GRAB (VF0254) - Others (VFC0346)] [Streptococcus pyogenes M1 GAS]
|
|
Isocitrate lyase
|
icl
|
1.0019468 |
138,591 |
VF0253
|
Others |
(icl) Isocitrate lyase Icl (isocitrase) (isocitratase) [Isocitrate lyase (VF0253) - Others (VFC0346)] [Mycobacterium tuberculosis H37Rv]
|
|
Gamma-hemolysin
|
hlgC
|
0.0002379 |
23 |
VF0011
|
Exotoxin |
(hlgA) gamma-hemolysin chain II precursor [Gamma-hemolysin (VF0011) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Intercellular adhesion proteins
|
icaB
|
0.0002452 |
22 |
VF0014
|
Biofilm |
(icaR) ica operon transcriptional regulator IcaR [Intercellular adhesion proteins (VF0014) - Biofilm (VFC0271)] [Staphylococcus aureus subsp. aureus MW2]
|
|
TcdB
|
toxB
|
0.0000144 |
2 |
VF0377
|
Exotoxin |
(toxB) toxin B [TcdB (VF0377) - Exotoxin (VFC0235)] [Clostridium difficile 630]
|
|
Shu
|
shuU
|
0.1584431 |
18,107 |
VF0256
|
Nutritional/Metabolic factor |
(shuT) periplasmic binding protein ShuT [Shu (VF0256) - Nutritional/Metabolic factor (VFC0272)] [Shigella dysenteriae Sd197]
|
|
Hyaluronate lyase
|
hysA
|
0.0002235 |
20 |
VF0013
|
Exoenzyme |
(hysA) hyaluronate lyase precursor [Hyaluronate lyase (VF0013) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Myf/pH6 antigen
|
psaB
|
0.0000072 |
1 |
VF0134
|
Adherence |
(psaB) chaperone protein PsaB [Myf/pH6 antigen (VF0134) - Adherence (VFC0001)] [Yersinia pestis CO92]
|
|
TcdA
|
toxA
|
0.0000072 |
1 |
VF0376
|
Exotoxin |
(toxA) toxin A [TcdA (VF0376) - Exotoxin (VFC0235)] [Clostridium difficile 630]
|
|
ShET2
|
senB
|
0.1133416 |
15,588 |
VF0258
|
Exotoxin |
(senB) enterotoxin [ShET2 (VF0258) - Exotoxin (VFC0235)] [Shigella boydii Sb227]
|
|
Eap/Map
|
eap/map
|
0.0000721 |
7 |
VF0016
|
Adherence |
(eap/map) extracellular adherence protein Eap/Map [Eap/Map (VF0016) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Isd
|
isdA
|
0.0005119 |
43 |
VF0015
|
Nutritional/Metabolic factor |
(harA) haptoglobin-binding heme uptake protein HarA [Isd (VF0015) - Nutritional/Metabolic factor (VFC0272)] [Staphylococcus aureus subsp. aureus str. Newman]
|
|
Yersiniabactin
|
fyuA/psn
|
3.4666479 |
52,601 |
VF0136
|
Nutritional/Metabolic factor |
(irp1) yersiniabactin biosynthetic protein Irp1 [Yersiniabactin (VF0136) - Nutritional/Metabolic factor (VFC0272)] [Yersinia pestis CO92]
|
|
SigA
|
sigA/rpoV
|
0.0006922 |
91 |
VF0257
|
Regulation |
(sigA/rpoV) RNA polymerase sigma factor SigA [SigA (VF0257) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
MOMP
|
ompA
|
0.0000072 |
1 |
VF1349
|
Adherence |
(ompA) outer membrane protein OmpA [MOMP (VF1349) - Adherence (VFC0001)] [Chlamydia trachomatis D/UW-3/CX]
|
|
Pla
|
pla
|
0.000822 |
104 |
VF0139
|
Exoenzyme |
(pla) plasminogen activator protease precursor [Pla (VF0139) - Exoenzyme (VFC0251)] [Yersinia pestis CO92]
|
|
PVL
|
lukS-PV
|
0.0000288 |
4 |
VF0018
|
Exotoxin |
(lukS-PV) Panton-Valentine leukocidin chain S precursor [PVL (VF0018) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Pmps
|
pmpC
|
0.0000433 |
1 |
VF1346
|
Adherence |
(pmpC) polymorphic membrane protein PmpC [Pmps (VF1346) - Adherence (VFC0001)] [Chlamydia trachomatis D/UW-3/CX]
|
|
F1 antigen
|
caf1M
|
0.0036846 |
502 |
VF0138
|
Immune modulation |
(caf1A) F1 capsule anchoring protein [F1 antigen (VF0138) - Immune modulation (VFC0258)] [Yersinia pestis CO92]
|
|
SpA
|
spa
|
0.0001154 |
13 |
VF0017
|
Exotoxin |
(spa) Immunoglobulin G binding protein A precursor [SpA (VF0017) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus MW2]
|
|
RtxA
|
rtxA
|
0.0000216 |
1 |
VF0259
|
Exotoxin |
(rtxA) structural toxin protein RtxA [RtxA (VF0259) - Exotoxin (VFC0235)] [Legionella pneumophila str. Paris]
|
|
SDr
|
sdrE
|
0.0005408 |
52 |
VF0019
|
Adherence |
(sdrC) Ser-Asp rich fibrinogen-binding bone sialoprotein-binding protein [SDr (VF0019) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
|
|
SLO
|
slo
|
0.0000216 |
1 |
VF0250
|
Exotoxin |
(slo) streptolysin O precursor [SLO (VF0250) - Exotoxin (VFC0235)] [Streptococcus pyogenes M1 GAS]
|
|
LPS
|
lpxD
|
0.0000577 |
8 |
VF0370
|
Immune modulation |
(kdsA) 3-deoxy-8-phosphooctulonate synthase [LPS (VF0370) - Immune modulation (VFC0258)] [Bartonella henselae str. Houston-1]
|
|
FnBPs
|
fnbA
|
0.0004759 |
43 |
VF0010
|
Adherence |
(fnbA) fibronectin-binding protein A [FnBPs (VF0010) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Flagella
|
fliF
|
0.0000937 |
10 |
VF0373
|
Motility |
(motA) lateral flagellar motor protein MotA [Flagella (VF0373) - Motility (VFC0204)] [Bartonella bacilliformis KC583]
|
|
Invasin
|
invA
|
0.0000072 |
1 |
VF0131
|
Invasion |
(invA) invasin Inv [Invasin (VF0131) - Invasion (VFC0083)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
Mitogenic factor
|
mf/spd
|
0.0000144 |
1 |
VF0252
|
Exoenzyme |
(mf/spd) deoxyribonuclease [Mitogenic factor (VF0252) - Exoenzyme (VFC0251)] [Streptococcus pyogenes M1 GAS]
|
|
Trw type IV secretion system
|
korA
|
0.0006706 |
28 |
VF0372
|
Effector delivery system |
(trwG) Trw type IV secretion sysmtem VirB8 homolog, trwG protein [Trw type IV secretion system (VF0372) - Effector delivery system (VFC0086)] [Bartonella henselae str. Houston-1]
|
|
SLS
|
sagA
|
0.0000072 |
1 |
VF0251
|
Exotoxin |
(sagA) streptolysin S associated protein [SLS (VF0251) - Exotoxin (VFC0235)] [Streptococcus pyogenes M1 GAS]
|
|
Ent
|
entS
|
0.0031582 |
189 |
VF0562
|
Nutritional/Metabolic factor |
(entD) enterochelin synthetase component D [Ent (VF0562) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
OatA
|
oatA
|
0.0001009 |
14 |
VF0441
|
Immune modulation |
(oatA) peptidoglycan O-acetyltransferase [OatA (VF0441) - Immune modulation (VFC0258)] [Listeria monocytogenes EGD-e]
|
|
Phospholipase C
|
plcA
|
0.0000216 |
2 |
VF0320
|
Exotoxin |
(plcA) membrane-associated phospholipase A [Phospholipase C (VF0320) - Exotoxin (VFC0235)] [Mycobacterium tuberculosis H37Rv]
|
|
LPS
|
KP1_RS17225
|
0.0596235 |
1,767 |
VF0561
|
Immune modulation |
(KP1_RS17230) glycosyltransferase [LPS (VF0561) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Ybt
|
ybtS
|
0.7840677 |
52,516 |
VF0564
|
Nutritional/Metabolic factor |
(ybtT) type II thioesterase YbtT [Ybt (VF0564) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
CadF
|
cadF
|
0.0000072 |
1 |
VF0322
|
Adherence |
(cadF) outer membrane fibronectin-binding protein [CadF (VF0322) - Adherence (VFC0001)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
|
|
Sal
|
iroN
|
0.0024011 |
228 |
VF0563
|
Nutritional/Metabolic factor |
(iroD) siderophore esterase IroD [Sal (VF0563) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
TTSS (SPI-2 encode)
|
ssaX
|
0.000447 |
35 |
VF0321
|
Effector delivery system |
(ssaD) type III secretion system outer MS ring protein SsaD [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
PgdA
|
pdgA
|
0.0000144 |
2 |
VF0442
|
Immune modulation |
(pdgA) Peptidoglycan N-deacetylase [PgdA (VF0442) - Immune modulation (VFC0258)] [Listeria monocytogenes EGD-e]
|
|
Type I fimbriae
|
fimI
|
0.7805418 |
101,581 |
VF0566
|
Adherence |
(fimG) type 1 fimbrial minor component [Type I fimbriae (VF0566) - Adherence (VFC0001)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
ToxB
|
toxB
|
0.3536885 |
28,718 |
VF0203
|
Effector delivery system |
(toxB) cytotoxin [ToxB (VF0203) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933]
|
|
InlJ
|
inlJ
|
0.0000072 |
1 |
VF0445
|
Adherence |
(inlJ) internalin J [InlJ (VF0445) - Adherence (VFC0001)] [Listeria monocytogenes EGD-e]
|
|
Capsule
|
glf
|
0.0229654 |
3,137 |
VF0323
|
Immune modulation |
(Cj1420c) methyltransferase [Capsule (VF0323) - Immune modulation (VFC0258)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
|
|
Aerobactin
|
iutA
|
0.2433898 |
30,936 |
VF0565
|
Nutritional/Metabolic factor |
(iucC) aerobactin siderophore biosynthesis protein IucC [Aerobactin (VF0565) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Intimin
|
eae
|
0.158335 |
21,915 |
VF0202
|
Effector delivery system |
(eae) intimin type gamma [Intimin (VF0202) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933]
|
|
Lap
|
lap
|
0.000447 |
53 |
VF0444
|
Adherence |
(lap) Listeria adhesion protein Lap [Lap (VF0444) - Adherence (VFC0001)] [Listeria monocytogenes EGD-e]
|
|
AcrAB
|
acrA
|
6.2746472 |
138,675 |
VF0568
|
Antimicrobial activity/Competitive advantage |
(acrB) acriflavine resistance protein B [AcrAB (VF0568) - Antimicrobial activity/Competitive advantage (VFC0325)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
LOS
|
gmhB
|
0.0001442 |
12 |
VF0326
|
Immune modulation |
(hldD) ADP-glyceromanno-heptose 6-epimerase [LOS (VF0326) - Immune modulation (VFC0258)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
|
|
Efa-1/LifA
|
lifA/efa1
|
0.1430632 |
16,432 |
VF0204
|
Effector delivery system |
(lifA/efa1) lymphostatin Efa1/LifA [Efa-1/LifA (VF0204) - Effector delivery system (VFC0086)] [Escherichia coli O103:H2 str. 12009]
|
|
Type 3 fimbriae
|
mrkI
|
0.0767844 |
1,909 |
VF0567
|
Biofilm |
(mrkC) fimbrial biogenesis outer membrane usher protein mrkC precursor [Type 3 fimbriae (VF0567) - Biofilm (VFC0271)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
LapB
|
lapB
|
0.0000072 |
1 |
VF0446
|
Adherence |
(lapB) Listeria adhesion protein LapB [LapB (VF0446) - Adherence (VFC0001)] [Listeria monocytogenes EGD-e]
|
|
Hemolysin
|
hlyA
|
1.303655 |
44,602 |
VF0207
|
Exotoxin |
(hlyA) Hemolysin A [Hemolysin (VF0207) - Exotoxin (VFC0235)] [Escherichia coli O157:H7 str. EDL933]
|
|
MOMP
|
porA
|
0.0000144 |
2 |
VF0328
|
Adherence |
(porA) major outer membrane protein [MOMP (VF0328) - Adherence (VFC0001)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
|
|
Stx
|
stx2B
|
1.1031604 |
29,494 |
VF0206
|
Exotoxin |
(stx2B) shiga-like toxin II B subunit encoded by bacteriophage BP-933W [Stx (VF0206) - Exotoxin (VFC0235)] [Escherichia coli O157:H7 str. EDL933]
|
|
T6SS
|
vipA/tssB
|
1.9091191 |
43,716 |
VF0569
|
Effector delivery system |
(icmF/tssM) type VI secretion protein TssM [T6SS (VF0569) - Effector delivery system (VFC0086)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
StcE
|
stcE
|
0.1398184 |
19,209 |
VF0209
|
Exoenzyme |
(stcE) metalloprotease [StcE (VF0209) - Exoenzyme (VFC0251)] [Escherichia coli O157:H7 str. EDL933]
|
|
EspP
|
espP
|
0.3544961 |
42,235 |
VF0208
|
Effector delivery system |
(espP) autotransporter, serine protease [EspP (VF0208) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933]
|
|
Capsule
|
rfbK1
|
11.3116298 |
138,646 |
VF0560
|
Immune modulation |
(KP1_RS17305) GDP-L-fucose synthase [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Flagella
|
motB
|
0.0010023 |
133 |
VF0430
|
Motility |
(tsr) methyl-accepting chemotaxis protein I [Flagella (VF0430) - Motility (VFC0204)] [Burkholderia pseudomallei K96243]
|
|
FupA
|
feoB
|
0.0001947 |
25 |
VF0550
|
Nutritional/Metabolic factor |
(feoB) Fe(2+) transporter permease subunit FeoB [FupA (VF0550) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
GGT
|
ggt
|
0.0005264 |
72 |
VF0553
|
Nutritional/Metabolic factor |
(ggt) gamma-glutamyltranspeptidase [GGT (VF0553) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
Antigen 85
|
fbpD
|
0.0000072 |
1 |
VF0311
|
Adherence |
(fbpD) MPT51/MPB51 antigen [Antigen 85 (VF0311) - Adherence (VFC0001)] [Mycobacterium tuberculosis H37Rv]
|
|
ESAT-6/CFP-10
|
esxA
|
0.0000072 |
1 |
VF0310
|
Effector delivery system |
(esxA) 6 kDa early secretory antigenic target EsxA (ESAT-6) [ESAT-6/CFP-10 (VF0310) - Effector delivery system (VFC0086)] [Mycobacterium tuberculosis H37Rv]
|
|
Biotin synthesis
|
bioB
|
0.0000072 |
1 |
VF0552
|
Nutritional/Metabolic factor |
(bioB) biotin synthase [Biotin synthesis (VF0552) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
HbhA
|
hbhA
|
0.0000072 |
1 |
VF0313
|
Adherence |
(hbhA) iron-regulated heparin binding hemagglutinin hbhA (adhesin) [HbhA (VF0313) - Adherence (VFC0001)] [Mycobacterium tuberculosis H37Rv]
|
|
Capsule I
|
wcbL
|
0.0040667 |
495 |
VF0436
|
Immune modulation |
(wcbL) sugar kinase [Capsule I (VF0436) - Immune modulation (VFC0258)] [Burkholderia pseudomallei K96243]
|
|
ESX-1
|
mycP1
|
0.000137 |
8 |
VF0315
|
Effector delivery system |
(espR) ESX-1 transcriptional regulator EspR [ESX-1 (VF0315) - Effector delivery system (VFC0086)] [Mycobacterium tuberculosis H37Rv]
|
|
Dot/Icm T4SS secreted effectors
|
sidC
|
0.0003605 |
15 |
VF0798
|
Effector delivery system |
(LPG_RS12830) Dot/Icm type IV secretion system effector [Dot/Icm T4SS secreted effectors (VF0798) - Effector delivery system (VFC0086)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
MmaA4
|
mmaA4
|
0.0000072 |
1 |
VF0314
|
Others |
(mmaA4) hydroxymycolate synthase MmaA4 [MmaA4 (VF0314) - Others (VFC0346)] [Mycobacterium tuberculosis H37Rv]
|
|
DevRS
|
devS
|
0.0000361 |
5 |
VF0317
|
Regulation |
(devS) two component sensor histidine kinase DevS [DevRS (VF0317) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
EtpA
|
etpB
|
0.0312358 |
1,274 |
VF0437
|
Adherence |
(etpA) Two-partner secreted adhesin EtpA [EtpA (VF0437) - Adherence (VFC0001)] [Escherichia coli O78:H11:K80 str. H10407]
|
|
Pyrimidine biosynthesis
|
carB
|
0.0061361 |
727 |
VF0558
|
Nutritional/Metabolic factor |
(carA) carbamoyl phosphate synthase small subunit [Pyrimidine biosynthesis (VF0558) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
PE/PE-PGRS
|
PE_PGRS30
|
0.0000072 |
1 |
VF0316
|
Immune modulation |
(PE_PGRS30) PE-PGRS family protein PE_PGRS30 [PE/PE-PGRS (VF0316) - Immune modulation (VFC0258)] [Mycobacterium tuberculosis H37Rv]
|
|
PanC/PanD
|
panC
|
0.0006706 |
85 |
VF0319
|
Nutritional/Metabolic factor |
(panC) pantothenate synthetase [PanC/PanD (VF0319) - Nutritional/Metabolic factor (VFC0272)] [Mycobacterium tuberculosis H37Rv]
|
|
LAM
|
capA
|
0.0000937 |
6 |
VF0318
|
Immune modulation |
(embC) arabinosyltransferase C [LAM (VF0318) - Immune modulation (VFC0258)] [Mycobacterium tuberculosis H37Rv]
|
|
InlK
|
inlK
|
0.0000072 |
1 |
VF0439
|
Immune modulation |
(inlK) internalin K [InlK (VF0439) - Immune modulation (VFC0258)] [Listeria monocytogenes EGD-e]
|
|
Type 1 fimbriae
|
fimI
|
8.2872295 |
131,197 |
VF0221
|
Adherence |
(fimF) FimF protein precursor [Type 1 fimbriae (VF0221) - Adherence (VFC0001)] [Escherichia coli CFT073]
|
|
Pyocyanin
|
phzH
|
0.001096 |
123 |
VF0100
|
Nutritional/Metabolic factor |
(phzS) flavin dependent hydroxylase PhzS [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1]
|
|
BfmRS
|
bfmS
|
0.0002163 |
29 |
VF0463
|
Regulation |
(bfmS) signal transduction histidine kinase [BfmRS (VF0463) - Regulation (VFC0301)] [Acinetobacter baumannii ACICU]
|
|
Petrobactin
|
asbE
|
0.0000937 |
6 |
VF0584
|
Nutritional/Metabolic factor |
(asbA) petrobactin biosynthesis protein AsbA [Petrobactin (VF0584) - Nutritional/Metabolic factor (VFC0272)] [Bacillus anthracis str. Sterne]
|
|
P fimbriae
|
papC
|
1.6582088 |
35,069 |
VF0220
|
Adherence |
(papA) P pilus major subunit PapA [P fimbriae (VF0220) - Adherence (VFC0001)] [Escherichia coli CFT073]
|
|
Bap
|
bap
|
0.0001658 |
19 |
VF0462
|
Biofilm |
(bap) biofilm-associated protein [Bap (VF0462) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU]
|
|
Cereulide
|
cesH
|
0.0000144 |
2 |
VF0583
|
Exotoxin |
(cesH) hydrolase, alpha/beta superfamily, CesH [Cereulide (VF0583) - Exotoxin (VFC0235)] [Bacillus cereus AH187]
|
|
Capsule
|
galE
|
0.0317333 |
3,153 |
VF0465
|
Immune modulation |
(ACICU_RS00405) polysaccharide biosynthesis/export family protein [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU]
|
|
Type 1 fimbriae
|
fimI
|
4.0695451 |
113,968 |
VF0102
|
Adherence |
(fimW) helix-turn-helix transcriptional regulator [Type 1 fimbriae (VF0102) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
TTSS
|
CT_560
|
0.0001442 |
4 |
VF0344
|
Effector delivery system |
(cdsJ) Type III secretion system inner membrane ring complex protein CdsJ [TTSS (VF0344) - Effector delivery system (VFC0086)] [Chlamydia trachomatis D/UW-3/CX]
|
|
Bacillibactin
|
dhbF
|
0.0002307 |
18 |
VF0586
|
Nutritional/Metabolic factor |
(dhbE) 2,3-dihydroxybenzoate adenylase DhbE [Bacillibactin (VF0586) - Nutritional/Metabolic factor (VFC0272)] [Bacillus cereus ATCC 10987]
|
|
Dr adhesins
|
draB
|
0.1965505 |
8,716 |
VF0223
|
Adherence |
(draP) DraP [Dr adhesins (VF0223) - Adherence (VFC0001)] [Escherichia coli O75:K5:H- str. IH11128]
|
|
S fimbriae
|
sfaC
|
0.2257746 |
6,234 |
VF0222
|
Adherence |
(sfaE) S fimbriae periplasmic chaperone SfaE [S fimbriae (VF0222) - Adherence (VFC0001)] [Escherichia coli UTI89]
|
|
Vi antigen
|
tviC
|
0.017197 |
2,378 |
VF0101
|
Immune modulation |
(tviB) Vi polysaccharide biosynthesis protein, UDP-N-acetylglucosamine (UPD-GlcNAc) 6-dehydrogenase TviB [Vi antigen (VF0101) - Immune modulation (VFC0258)] [Salmonella enterica subsp. enterica serovar Typhi str. CT18]
|
|
OmpA
|
ompA
|
0.0001082 |
15 |
VF0464
|
Immune modulation |
(ompA) outer membrane protein OmpA [OmpA (VF0464) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU]
|
|
Pef
|
pefA
|
0.0339037 |
3,861 |
VF0104
|
Adherence |
(pefB) plasmid-encoded fimbriae regulatory protein PefB [Pef (VF0104) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
LpeA
|
lpeA
|
0.0000144 |
2 |
VF0346
|
Invasion |
(lpeA) lipoprotein promoting cell invasion [LpeA (VF0346) - Invasion (VFC0083)] [Listeria monocytogenes EGD-e]
|
|
Alpha-Hemolysin
|
hlyA
|
0.3286826 |
11,057 |
VF0225
|
Exotoxin |
(hlyC) Hemolysin C [Alpha-Hemolysin (VF0225) - Exotoxin (VFC0235)] [Escherichia coli CFT073]
|
|
Acinetobactin
|
barA
|
0.0007715 |
72 |
VF0467
|
Nutritional/Metabolic factor |
(basG) acinetobactin biosynthesis protein BasF [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU]
|
|
F1C fimbriae
|
C_RS05810
|
1.0811756 |
105,639 |
VF0224
|
Adherence |
(focD) F1C fimbrial usher [F1C fimbriae (VF0224) - Adherence (VFC0001)] [Escherichia coli CFT073]
|
|
LPS
|
lpsB
|
0.0002379 |
24 |
VF0466
|
Immune modulation |
(lpxA) acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU]
|
|
Agf
|
csgE
|
0.0021631 |
254 |
VF0103
|
Adherence |
(csgC) curli assembly protein CsgC [Agf (VF0103) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Hal
|
hal
|
0.0000144 |
2 |
VF0587
|
Nutritional/Metabolic factor |
(hal) heme-acquisition leucine-rich repeat protein [Hal (VF0587) - Nutritional/Metabolic factor (VFC0272)] [Bacillus anthracis str. Sterne]
|
|
Chu
|
chuX
|
1.9414148 |
56,797 |
VF0227
|
Nutritional/Metabolic factor |
(chuT) periplasmic heme-binding protein ChuT [Chu (VF0227) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073]
|
|
MgtB
|
mgtB
|
0.002603 |
334 |
VF0106
|
Nutritional/Metabolic factor |
(mgtB) Mg2+ transport protein [MgtB (VF0106) - Nutritional/Metabolic factor (VFC0272)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Phospholipase D
|
plcD
|
0.0000505 |
7 |
VF0469
|
Exotoxin |
(plcD) phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase [Phospholipase D (VF0469) - Exotoxin (VFC0235)] [Acinetobacter baumannii ACICU]
|
|
PbpG
|
pbpG
|
0.0000577 |
8 |
VF0468
|
Immune modulation |
(pbpG) D-alanyl-D-alanine endopeptidase PBP7/8 [PbpG (VF0468) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU]
|
|
LplA1
|
lplA1
|
0.0000577 |
7 |
VF0347
|
Nutritional/Metabolic factor |
(lplA1) lipoate protein ligase [LplA1 (VF0347) - Nutritional/Metabolic factor (VFC0272)] [Listeria monocytogenes EGD-e]
|
|
CNF-1
|
cnf1
|
0.0541723 |
7,099 |
VF0226
|
Exotoxin |
(cnf1) cytotoxic necrotizing factor 1 [CNF-1 (VF0226) - Exotoxin (VFC0235)] [Escherichia coli UTI89]
|
|
Lpf
|
lpfD
|
1.3568611 |
57,469 |
VF0105
|
Adherence |
(lpfE) long polar fimbrial minor subunit LpfE, adhesin [Lpf (VF0105) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
SlpA
|
slpA
|
0.0000072 |
1 |
VF0589
|
Adherence |
(slpA) cell surface protein (S-layer precursor protein) [SlpA (VF0589) - Adherence (VFC0001)] [Clostridium difficile 630]
|
|
Rck
|
rck
|
0.029837 |
3,658 |
VF0108
|
Invasion |
(rck) resistance to complement killing [Rck (VF0108) - Invasion (VFC0083)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Aerobactin
|
iutA
|
1.2319756 |
51,323 |
VF0229
|
Nutritional/Metabolic factor |
(iutA) ferric aerobactin receptor precusor IutA [Aerobactin (VF0229) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073]
|
|
Enterobactin
|
entS
|
13.9730833 |
138,604 |
VF0228
|
Nutritional/Metabolic factor |
(entE) 2,3-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073]
|
|
FbpA
|
fbpA
|
0.0000216 |
3 |
VF0349
|
Adherence |
(fbpA) fibronectin-binding protein [FbpA (VF0349) - Adherence (VFC0001)] [Listeria monocytogenes EGD-e]
|
|
SodCI
|
sodCI
|
0.0340263 |
4,482 |
VF0109
|
Stress survival |
(sodCI) Gifsy-2 prophage: superoxide dismutase precursor (Cu-Zn) [SodCI (VF0109) - Stress survival (VFC0282)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
CPAF
|
CT_858
|
0.0000072 |
1 |
VF0580
|
Exoenzyme |
(CT_858) serine protease [CPAF (VF0580) - Exoenzyme (VFC0251)] [Chlamydia trachomatis D/UW-3/CX]
|
|
Exolysin
|
exlA
|
0.0000144 |
2 |
VF0582
|
Effector delivery system |
(exlA) hemolysin [Exolysin (VF0582) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PA7]
|
|
Csu fimbriae
|
csuC
|
0.0000721 |
8 |
VF0461
|
Biofilm |
(csuC) Csu pilus chaperone protein CsuC [Csu fimbriae (VF0461) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU]
|
|
EF-Tu
|
tufA
|
3.6077787 |
138,615 |
VF0460
|
Adherence |
(tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
T7SS
|
esxL
|
0.0000072 |
1 |
VF0581
|
Effector delivery system |
(esxL) type VII secretion system protein EsxL [T7SS (VF0581) - Effector delivery system (VFC0086)] [Bacillus anthracis str. Sterne]
|
|
Colibactin
|
clbG
|
1.0075638 |
13,092 |
VF0573
|
Exotoxin |
(clbC) colibactin polyketide synthase ClbC [Colibactin (VF0573) - Exotoxin (VFC0235)] [Klebsiella pneumoniae subsp. pneumoniae 1084]
|
|
Heat-labile toxin (LT)
|
eltB
|
0.0222011 |
1,522 |
VF0210
|
Exotoxin |
(eltB) enterotoxin subunit B (from human) [Heat-labile toxin (LT) (VF0210) - Exotoxin (VFC0235)] [Escherichia coli O78:H11:K80 str. H10407]
|
|
FHbp
|
fHbp
|
0.0000072 |
1 |
VF0452
|
Immune modulation |
(fHbp) factor H binding protein [FHbp (VF0452) - Immune modulation (VFC0258)] [Neisseria meningitidis MC58]
|
|
Allantion utilization
|
allB
|
6.0606401 |
138,368 |
VF0572
|
Nutritional/Metabolic factor |
(allB) allantoinase [Allantion utilization (VF0572) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
MtrCDE
|
mtrE
|
0.0001009 |
14 |
VF0451
|
Antimicrobial activity/Competitive advantage |
(mtrD) multiple transferable resistance system protein MtrD [MtrCDE (VF0451) - Antimicrobial activity/Competitive advantage (VFC0325)] [Neisseria meningitidis MC58]
|
|
KatA
|
katA
|
0.0006778 |
91 |
VF0454
|
Stress survival |
(katA) catalase [KatA (VF0454) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
|
|
T4SS secreted effectors
|
coxH2/rimL
|
0.0028121 |
380 |
VF0696
|
Effector delivery system |
(CBU_0270) Coxiella Dot/Icm type IVB secretion system translocated effector, trans-2-enoyl-CoA reductase [T4SS secreted effectors (VF0696) - Effector delivery system (VFC0086)] [Coxiella burnetii RSA 493]
|
|
T2SS
|
gspD
|
6.4025467 |
95,141 |
VF0333
|
Effector delivery system |
(gspI) general secretion pathway protein I [T2SS (VF0333) - Effector delivery system (VFC0086)] [Shigella dysenteriae Sd197]
|
|
Afa/Dr family
|
draE2
|
0.0129644 |
1,796 |
VF0212
|
Adherence |
(draE2) Dr-II structural adhesin precursor [Afa/Dr family (VF0212) - Adherence (VFC0001)] [Escherichia coli EC7372]
|
|
Invasin C/Ilp
|
invC/ilp
|
0.0000216 |
3 |
VF0575
|
Invasion |
(invC/ilp) intimin-like invasin C protein [Invasin C/Ilp (VF0575) - Invasion (VFC0083)] [Yersinia pseudotuberculosis IP 31758]
|
|
Heat-stable toxin (ST)
|
estIa
|
0.0180911 |
2,140 |
VF0211
|
Exotoxin |
(estIa) heat stable enterotoxin I [Heat-stable toxin (ST) (VF0211) - Exotoxin (VFC0235)] [Escherichia coli O78:H11:K80 str. H10407]
|
|
T4SS secreted effectors
|
ricA
|
0.0000288 |
3 |
VF0695
|
Effector delivery system |
(BPE005) type IV secretion system effector, cyclic nucleotide-binding domain-containing protein [T4SS secreted effectors (VF0695) - Effector delivery system (VFC0086)] [Brucella melitensis bv. 1 str. 16M]
|
|
VAS T6SS
|
icmF/vasK
|
0.003324 |
456 |
VF0335
|
Effector delivery system |
(icmF/vasK) type VI secretion system inner membrane protein VasK [VAS T6SS (VF0335) - Effector delivery system (VFC0086)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
AAFs
|
aafC
|
0.0628538 |
4,274 |
VF0214
|
Adherence |
(aafC) aggregative adherence fimbria II usher protein AafC [AAFs (VF0214) - Adherence (VFC0001)] [Escherichia coli O44:H18 042]
|
|
MsrAB
|
msrA/B(pilB
|
0.0019901 |
244 |
VF0456
|
Stress survival |
(msrA/B(pilB)) trifunctional thioredoxin/methionine sulfoxide reductase A/B protein [MsrAB (VF0456) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
|
|
Invasin D
|
invD
|
0.0001154 |
16 |
VF0576
|
Invasion |
(invD) invasin D protein [Invasin D (VF0576) - Invasion (VFC0083)] [Yersinia pseudotuberculosis IP 31758]
|
|
HSI-1
|
icmF1/tssM1
|
0.0015503 |
108 |
VF0334
|
Effector delivery system |
(hsiF1/tssE) type VI secretion system hcp secretion island protein HsiF1, a gp25-like protein, but not exhibit lysozyme activity [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
Adhesive fimbriae
|
cfaD/cfaE
|
1.9677691 |
67,344 |
VF0213
|
Adherence |
(cfaD/cfaE) minor pilin and initiator [Adhesive fimbriae (VF0213) - Adherence (VFC0001)] [Escherichia coli E24377A]
|
|
MntABC
|
mntC
|
0.0001009 |
14 |
VF0455
|
Stress survival |
(mntB) Manganese transport system membrane protein MntB [MntABC (VF0455) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
|
|
T6SS
|
hcp1/tssD1
|
15.8279074 |
118,669 |
VF0579
|
Effector delivery system |
(tssG) Type VI secretion system protein TssG [T6SS (VF0579) - Effector delivery system (VFC0086)] [Shigella sonnei Ss046]
|
|
BvgAS
|
bvgA
|
0.0000649 |
9 |
VF0336
|
Regulation |
(bvgS) virulence factors two-component system sensor histidine kinase BvgS [BvgAS (VF0336) - Regulation (VFC0301)] [Bordetella pertussis Tohama I]
|
|
RecN
|
recN
|
0.0003389 |
47 |
VF0457
|
Stress survival |
(recN) DNA repair protein RecN [RecN (VF0457) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
|
|
Dispersin
|
aatA
|
0.1412822 |
4,334 |
VF0215
|
Others |
(aatA) outer membrane protein AatA [Dispersin (VF0215) - Others (VFC0346)] [Escherichia coli O44:H18 042]
|
|
Pic
|
pic
|
0.0280488 |
3,862 |
VF0218
|
Effector delivery system |
(pic) Pic serine protease precursor, autotransporter [Pic (VF0218) - Effector delivery system (VFC0086)] [Escherichia coli O44:H18 042]
|
|
Pet
|
pet
|
0.0440849 |
5,449 |
VF0217
|
Effector delivery system |
(pet) Pet serine protease precursor, autotransporter [Pet (VF0217) - Effector delivery system (VFC0086)] [Escherichia coli O44:H18 042]
|
|
FarAB
|
farB
|
0.0049824 |
648 |
VF0450
|
Antimicrobial activity/Competitive advantage |
(farA) fatty acid efflux system protein FarA [FarAB (VF0450) - Antimicrobial activity/Competitive advantage (VFC0325)] [Neisseria meningitidis MC58]
|
|
RcsAB
|
rcsB
|
1.9954141 |
138,594 |
VF0571
|
Regulation |
(rcsA) transcriptional activator for ctr capsule biosynthesis [RcsAB (VF0571) - Regulation (VFC0301)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
RmpA
|
rmpA
|
0.000274 |
24 |
VF0570
|
Regulation |
(rmpA2) regulator of mucoid phenotype RmpA2 [RmpA (VF0570) - Regulation (VFC0301)] [Klebsiella pneumoniae CG43]
|
|
Rhamnolipid
|
rhlC
|
0.0000505 |
4 |
VF0089
|
Immune modulation |
(rhlA) rhamnosyltransferase chain A [Rhamnolipid (VF0089) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1]
|
|
LasA
|
lasA
|
0.0000072 |
1 |
VF0088
|
Effector delivery system |
(lasA) LasA protease precursor [LasA (VF0088) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
Porin
|
porB
|
0.0000216 |
2 |
VF0081
|
Invasion |
(porB) major outer membrane protein PIB [Porin (VF0081) - Invasion (VFC0083)] [Neisseria meningitidis MC58]
|
|
IgA1 protease
|
iga
|
0.0000072 |
1 |
VF0080
|
Effector delivery system |
(iga) IgA-specific serine endopeptidase [IgA1 protease (VF0080) - Effector delivery system (VFC0086)] [Neisseria meningitidis MC58]
|
|
TTSS
|
pcr3
|
0.000548 |
33 |
VF0083
|
Effector delivery system |
(pscQ) type III secretion system protein PscQ [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
Type IV pili
|
vfr
|
1.00274 |
138,628 |
VF0082
|
Adherence |
(pilY1) type 4 fimbrial biogenesis protein PilY1 [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1]
|
|
LPS
|
PA3143
|
0.0080974 |
939 |
VF0085
|
Immune modulation |
(wzx) O-antigen translocase [LPS (VF0085) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1]
|
|
Xcp secretion system
|
xcpP
|
0.0003173 |
29 |
VF0084
|
Effector delivery system |
(xcpP) secretion protein XcpP [Xcp secretion system (VF0084) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
LasB
|
lasB
|
0.0000288 |
4 |
VF0087
|
Effector delivery system |
(lasB) elastase LasB [LasB (VF0087) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
ExoA
|
toxA
|
0.0000288 |
4 |
VF0086
|
Exotoxin |
(toxA) exotoxin A precursor [ExoA (VF0086) - Exotoxin (VFC0235)] [Pseudomonas aeruginosa PAO1]
|
|
LOS
|
rfaC
|
0.0000505 |
6 |
VF0078
|
Immune modulation |
(rfaC) lipopolysaccharide heptosyltransferase I [LOS (VF0078) - Immune modulation (VFC0258)] [Neisseria meningitidis MC58]
|
|
Capsule
|
ctrD
|
0.0000144 |
2 |
VF0079
|
Immune modulation |
(lipB) capsule polysaccharide modification protein LipB [Capsule (VF0079) - Immune modulation (VFC0258)] [Neisseria meningitidis MC58]
|
|
TTSS
|
escD
|
7.3545538 |
42,620 |
VF0191
|
Effector delivery system |
(cesF) CesF, chaperone for EspF [TTSS (VF0191) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933]
|
|
InlB
|
inlB
|
0.0000072 |
1 |
VF0070
|
Invasion |
(inlB) Internalin B [InlB (VF0070) - Invasion (VFC0083)] [Listeria monocytogenes EGD-e]
|
|
Per
|
bfpV
|
0.0244507 |
1,889 |
VF0190
|
Regulation |
(bfpW) BfpW [Per (VF0190) - Regulation (VFC0301)] [Escherichia coli B171]
|
|
ClpC
|
clpC
|
0.0020045 |
235 |
VF0072
|
Stress survival |
(clpC) endopeptidase Clp ATP-binding chain C [ClpC (VF0072) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
|
|
Ler
|
ler
|
0.1248783 |
17,316 |
VF0192
|
Regulation |
(ler) transcription regulator Ler [Ler (VF0192) - Regulation (VFC0301)] [Escherichia coli O157:H7 str. EDL933]
|
|
Ami
|
ami
|
0.0000072 |
1 |
VF0071
|
Adherence |
(ami) autolysin amidase, adhesin [Ami (VF0071) - Adherence (VFC0001)] [Listeria monocytogenes EGD-e]
|
|
ClpP
|
clpP
|
1.0008292 |
138,611 |
VF0074
|
Stress survival |
(clpP) ATP-dependent Clp protease proteolytic subunit [ClpP (VF0074) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
|
|
ClpE
|
clpE
|
0.000137 |
15 |
VF0073
|
Stress survival |
(clpE) ATP-dependent protease [ClpE (VF0073) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
|
|
Paa
|
paa
|
0.2566715 |
35,393 |
VF0194
|
Adherence |
(paa) outer membrane adhesin Paa [Paa (VF0194) - Adherence (VFC0001)] [Escherichia coli O157:H7 str. EDL933]
|
|
Opa
|
opa
|
0.0000144 |
2 |
VF0076
|
Invasion |
(opa) outer membrane beta-barrel protein [Opa (VF0076) - Invasion (VFC0083)] [Neisseria meningitidis MC58]
|
|
Type IV pili
|
pilG
|
0.0010239 |
132 |
VF0075
|
Adherence |
(pilG) pilus assembly protein PilG [Type IV pili (VF0075) - Adherence (VFC0001)] [Neisseria meningitidis MC58]
|
|
HSI-1 T6SS secreted effectors
|
tse6
|
0.0001731 |
15 |
VF1194
|
Effector delivery system |
(tse3) type VI secretion system effector Tse3, glycoside hydrolase [HSI-1 T6SS secreted effectors (VF1194) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
Fap
|
fapD
|
0.0000865 |
5 |
VF1191
|
Adherence |
(fapF) outer membrane secretin FapF [Fap (VF1191) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1]
|
|
SCI T6SS secreted effectors
|
tae4
|
0.0495793 |
4,413 |
VF1195
|
Effector delivery system |
(tae4) type VI secretion system effector tae4, L,D-endopeptidase [SCI T6SS secreted effectors (VF1195) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
EsxG-EsxH
|
esxG
|
0.0000072 |
1 |
VF1196
|
Effector delivery system |
(esxG) Type VII secretion system protein EsxG [EsxG-EsxH (VF1196) - Effector delivery system (VFC0086)] [Mycobacterium tuberculosis H37Rv]
|
|
Alkaline protease
|
aprA
|
0.0000937 |
13 |
VF0090
|
Exoenzyme |
(aprA) alkaline metalloproteinase precursor [Alkaline protease (VF0090) - Exoenzyme (VFC0251)] [Pseudomonas aeruginosa PAO1]
|
|
PLC
|
plcH
|
0.0000361 |
5 |
VF0092
|
Exotoxin |
(plcH) hemolytic phospholipase C precursor [PLC (VF0092) - Exotoxin (VFC0235)] [Pseudomonas aeruginosa PAO1]
|
|
Alginate
|
algI
|
1.0025597 |
138,625 |
VF0091
|
Biofilm |
(algL) poly(beta-d-mannuronate) lyase precursor AlgL [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1]
|
|
Pyoverdine
|
pvdS
|
0.0010167 |
77 |
VF0094
|
Nutritional/Metabolic factor |
(PA2384) hypothetical protein [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1]
|
|
Quorum sensing
|
rhlI
|
0.0015647 |
212 |
VF0093
|
Biofilm |
(lasI) autoinducer synthesis protein LasI [Quorum sensing (VF0093) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1]
|
|
Pyochelin
|
pchI
|
0.0072321 |
966 |
VF0095
|
Nutritional/Metabolic factor |
(pchB) salicylate biosynthesis protein PchB [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1]
|
|
RelA
|
relA
|
0.0000577 |
7 |
VF0287
|
Regulation |
(relA) Probable GTP pyrophosphokinase RelA (ATP:GTP 3'-pyrophosphotransferase) (PPGPP synthetase I) ((P)PPGPP synthetase) (GTP diphosphokinase) [RelA (VF0287) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
LOS
|
rfaD
|
12.6539402 |
138,676 |
VF0044
|
Immune modulation |
(msbA) lipid transporter ATP-binding/permease [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20]
|
|
PhoP
|
phoP
|
0.0000216 |
3 |
VF0286
|
Regulation |
(phoR) Possible two component system response sensor kinase membrane associated PhoR [PhoP (VF0286) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
KatAB
|
katA
|
0.2423731 |
32,887 |
VF0168
|
Stress survival |
(katA) catalase/(hydro)peroxidase [KatAB (VF0168) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Lbp
|
lbpA
|
0.0000144 |
1 |
VF0047
|
Nutritional/Metabolic factor |
(lbpA) lactoferrin-binding protein A [Lbp (VF0047) - Nutritional/Metabolic factor (VFC0272)] [Neisseria meningitidis MC58]
|
|
MgtC
|
mgtC
|
0.0000144 |
2 |
VF0289
|
Nutritional/Metabolic factor |
(mgtC) Possible Mg2+ transport P-type ATPase C MgtC [MgtC (VF0289) - Nutritional/Metabolic factor (VFC0272)] [Mycobacterium tuberculosis H37Rv]
|
|
Tbp
|
tbpB
|
0.0000288 |
3 |
VF0046
|
Nutritional/Metabolic factor |
(tbpB) transferrin-binding protein B [Tbp (VF0046) - Nutritional/Metabolic factor (VFC0272)] [Neisseria meningitidis MC58]
|
|
HpuAB
|
hpuA
|
0.0000216 |
2 |
VF0049
|
Nutritional/Metabolic factor |
(hpuB) haemoglobin-haptoglobin-utilization protein [HpuAB (VF0049) - Nutritional/Metabolic factor (VFC0272)] [Neisseria meningitidis Z2491]
|
|
SodB
|
sodB
|
1.0033024 |
138,608 |
VF0169
|
Stress survival |
(sodB) superoxide dismutase [SodB (VF0169) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
HmbR
|
hmbR
|
0.0000072 |
1 |
VF0048
|
Nutritional/Metabolic factor |
(hmbR) hemoglobin receptor [HmbR (VF0048) - Nutritional/Metabolic factor (VFC0272)] [Neisseria meningitidis MC58]
|
|
Curli fibers
|
csgC
|
6.9951473 |
138,556 |
VF1138
|
Adherence |
(csgB) curlin minor subunit CsgB [Curli fibers (VF1138) - Adherence (VFC0001)] [Escherichia coli O25b:H4-ST131]
|
|
FeoAB
|
feoB
|
0.0003173 |
43 |
VF0160
|
Nutritional/Metabolic factor |
(feoB) ferrous iron transporter B [FeoAB (VF0160) - Nutritional/Metabolic factor (VFC0272)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Hyaluronidase
|
hylB
|
0.0000072 |
1 |
VF0281
|
Exoenzyme |
(hylB) hyaluronidase [Hyaluronidase (VF0281) - Exoenzyme (VFC0251)] [Streptococcus agalactiae NEM316]
|
|
CAMP factor
|
cfa/cfb
|
0.0000072 |
1 |
VF0280
|
Exotoxin |
(cfa/cfb) cAMP factor [CAMP factor (VF0280) - Exotoxin (VFC0235)] [Streptococcus agalactiae NEM316]
|
|
PmiA
|
LPG_RS08655
|
0.0000072 |
1 |
VF0162
|
Others |
(LPG_RS08655) DUF1189 family protein [PmiA (VF0162) - Others (VFC0346)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Capsule
|
bcs2'
|
0.0002163 |
30 |
VF0043
|
Immune modulation |
(bcs1') Bcs1' [Capsule (VF0043) - Immune modulation (VFC0258)] [Haemophilus influenzae str. 1007]
|
|
Enh loci
|
LPG_RS06795
|
0.0000144 |
1 |
VF0163
|
Others |
(LPG_RS06795) SEL1-like repeat protein [Enh loci (VF0163) - Others (VFC0346)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
IdeS
|
ideS/mac
|
0.0000216 |
1 |
VF0284
|
Immune modulation |
(ideS/mac) immunoglobulin G-degrading enzyme [IdeS (VF0284) - Immune modulation (VFC0258)] [Streptococcus pyogenes M1 GAS]
|
|
MisL
|
misL
|
0.021754 |
1,693 |
VF0397
|
Adherence |
(misL) putative autotransporter [MisL (VF0397) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
ArtAB
|
artB
|
0.0207446 |
2,336 |
VF1366
|
Exotoxin |
(artB) ADP-ribosyltransferase toxin subunit ArtB [ArtAB (VF1366) - Exotoxin (VFC0235)] [Salmonella enterica subsp. enterica serovar Typhimurium str. DT104]
|
|
Type IV pili
|
pilW
|
0.0001586 |
19 |
VF0155
|
Adherence |
(pilC) type IV pilus assembly protein PilC [Type IV pili (VF0155) - Adherence (VFC0001)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Brk
|
brkB
|
0.0000072 |
1 |
VF0034
|
Immune modulation |
(brkB) serum resistance protein [Brk (VF0034) - Immune modulation (VFC0258)] [Bordetella pertussis Tohama I]
|
|
LPS
|
bplL
|
0.0022857 |
188 |
VF0033
|
Immune modulation |
(bplB) probable acetyltransferase [LPS (VF0033) - Immune modulation (VFC0258)] [Bordetella pertussis Tohama I]
|
|
Lsp T2SS
|
lspI
|
0.0000649 |
6 |
VF0154
|
Effector delivery system |
(lspE) general secretion pathway protein E [Lsp T2SS (VF0154) - Effector delivery system (VFC0086)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Lmb
|
lmb
|
0.0000144 |
1 |
VF0275
|
Adherence |
(lmb) laminin-binding surface protein [Lmb (VF0275) - Adherence (VFC0001)] [Streptococcus agalactiae NEM316]
|
|
Mig-5
|
mig-5
|
0.0000072 |
1 |
VF0396
|
Antimicrobial activity/Competitive advantage |
(mig-5) putative carbonic anhydrase [Mig-5 (VF0396) - Antimicrobial activity/Competitive advantage (VFC0325)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Flagella
|
fliC
|
0.000959 |
122 |
VF0157
|
Motility |
(fliI) flagellum-specific ATP synthase FliI [Flagella (VF0157) - Motility (VFC0204)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
RatB
|
ratB
|
0.0004687 |
59 |
VF0399
|
Adherence |
(ratB) putative outer membrane protein [RatB (VF0399) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Haemagglutinating pili
|
hifB
|
0.0000361 |
5 |
VF0036
|
Adherence |
(hifB) periplasmic chaperone [Haemagglutinating pili (VF0036) - Adherence (VFC0001)] [Haemophilus influenzae AM30 (770235)]
|
|
C5a peptidase
|
scpA/scpB
|
0.0000216 |
1 |
VF0278
|
Adherence |
(scpA/scpB) streptococcal C5a peptidase [C5a peptidase (VF0278) - Adherence (VFC0001)] [Streptococcus agalactiae NEM316]
|
|
TTSS
|
BP_RS11160
|
0.0000505 |
7 |
VF0035
|
Effector delivery system |
(BP_RS11160) hypothetical protein [TTSS (VF0035) - Effector delivery system (VFC0086)] [Bordetella pertussis Tohama I]
|
|
Dot/Icm
|
icmV
|
0.0000505 |
4 |
VF0156
|
Effector delivery system |
(dotD) Dot/Icm type IV secretion system outer membrane subcomplex protein DotD [Dot/Icm (VF0156) - Effector delivery system (VFC0086)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
MgtC
|
mgtC
|
0.0001586 |
21 |
VF1365
|
Nutritional/Metabolic factor |
(mgtC) Salmonella virulence protein MgtC [MgtC (VF1365) - Nutritional/Metabolic factor (VFC0272)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
ShdA
|
shdA
|
0.0001947 |
27 |
VF0398
|
Adherence |
(shdA) AIDA autotransporter-like protein [ShdA (VF0398) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Hsp60
|
htpB
|
1.2335403 |
138,622 |
VF0159
|
Adherence |
(htpB) Hsp60, 60K heat shock protein HtpB [Hsp60 (VF0159) - Adherence (VFC0001)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
HMW1/HMW2
|
hmw2C
|
0.0000072 |
1 |
VF0038
|
Adherence |
(hmw2C) glycosyltransferase [HMW1/HMW2 (VF0038) - Adherence (VFC0001)] [Haemophilus influenzae str. 12]
|
|
Beta-haemolysin/cytolysin
|
cylA
|
0.0000144 |
2 |
VF0279
|
Exotoxin |
(cylA) ABC (ATP-binding cassette) transporter CylA [Beta-haemolysin/cytolysin (VF0279) - Exotoxin (VFC0235)] [Streptococcus agalactiae NEM316]
|
|
Hap
|
hap
|
0.0000072 |
1 |
VF0037
|
Adherence |
(hap) adhesion and penetration protein Hap [Hap (VF0037) - Adherence (VFC0001)] [Haemophilus influenzae N187]
|
|
CNFy
|
cnf
|
0.0004398 |
57 |
VF0393
|
Exotoxin |
(cnf) cytotoxic necrotizing factor [CNFy (VF0393) - Exotoxin (VFC0235)] [Yersinia pseudotuberculosis YPIII]
|
|
FbpABC
|
fbpC
|
0.0000433 |
6 |
VF0272
|
Nutritional/Metabolic factor |
(fbpC) iron(III) ABC transporter, ATP-binding protein [FbpABC (VF0272) - Nutritional/Metabolic factor (VFC0272)] [Neisseria meningitidis MC58]
|
|
PsaA
|
psaA
|
0.0000144 |
2 |
VF0151
|
Nutritional/Metabolic factor |
(psaA) manganese ABC transporter, manganese-binding adhesion liprotein [PsaA (VF0151) - Nutritional/Metabolic factor (VFC0272)] [Streptococcus pneumoniae TIGR4]
|
|
O-antigen
|
galE
|
0.1912869 |
14,494 |
VF0392
|
Immune modulation |
(YE_RS15420) mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase [O-antigen (VF0392) - Immune modulation (VFC0258)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
Capsule
|
neuB
|
0.0003173 |
31 |
VF0274
|
Immune modulation |
(neuB) N-acetylneuraminate synthase [Capsule (VF0274) - Immune modulation (VFC0258)] [Streptococcus agalactiae NEM316]
|
|
Mig-14
|
mig-14
|
0.0003389 |
47 |
VF0395
|
Antimicrobial activity/Competitive advantage |
(mig-14) antimicrobial peptide resistance protein Mig-14 [Mig-14 (VF0395) - Antimicrobial activity/Competitive advantage (VFC0325)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Mip
|
mip
|
0.0000072 |
1 |
VF0153
|
Post-translational modification |
(mip) macrophage infectivity potentiator Mip [Mip (VF0153) - Post-translational modification (VFC0315)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Flagella
|
fleI/flaG
|
0.0041677 |
411 |
VF0273
|
Motility |
(PA1458) two-component sensor [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1]
|
|
Flagella
|
motB
|
32.8485222 |
138,648 |
VF0394
|
Motility |
(fliL) flagellar basal body protein FliL [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
PspA
|
pspA
|
0.0000144 |
2 |
VF0152
|
Immune modulation |
(pspA) surface protein A [PspA (VF0152) - Immune modulation (VFC0258)] [Streptococcus pneumoniae TIGR4]
|
|
PlcB
|
plcB
|
0.0000072 |
1 |
VF0067
|
Exotoxin |
(plcB) phospholipase C [PlcB (VF0067) - Exotoxin (VFC0235)] [Listeria monocytogenes EGD-e]
|
|
Ysa TTSS effectors
|
YE_RS12240
|
0.0001082 |
14 |
VF1037
|
Effector delivery system |
(YE_RS12240) protein kinase [Ysa TTSS effectors (VF1037) - Effector delivery system (VFC0086)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
Ler
|
AAC38364
|
0.1753805 |
24,315 |
VF0189
|
Regulation |
(AAC38364) Orf1 [Ler (VF0189) - Regulation (VFC0301)] [Escherichia coli O127:H6 str. E2348/69]
|
|
PlcA
|
plcA
|
0.0000072 |
1 |
VF0063
|
Exotoxin |
(plcA) phosphatidylinositol-specific phospholipase c [PlcA (VF0063) - Exotoxin (VFC0235)] [Listeria monocytogenes EGD-e]
|
|
Mpl
|
mpl
|
0.0000072 |
1 |
VF0065
|
Exoenzyme |
(mpl) Zinc metalloproteinase precursor [Mpl (VF0065) - Exoenzyme (VFC0251)] [Listeria monocytogenes EGD-e]
|
|
CDT
|
cdtA
|
0.0427509 |
2,003 |
VF0185
|
Exotoxin |
(cdtA) cytolethal distending toxin A [CDT (VF0185) - Exotoxin (VFC0235)] [Escherichia coli O157:H str. 493/89]
|
|
LLO
|
hly
|
0.0000072 |
1 |
VF0064
|
Exotoxin |
(hly) listeriolysin O precursor [LLO (VF0064) - Exotoxin (VFC0235)] [Listeria monocytogenes EGD-e]
|
|
Ysa TTSS
|
ysaQ
|
0.0161443 |
2,225 |
VF1025
|
Effector delivery system |
(sycB) type III secretion system translocator chaperone SicA [Ysa TTSS (VF1025) - Effector delivery system (VFC0086)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
Intimin
|
eae
|
0.149293 |
20,683 |
VF0177
|
Effector delivery system |
(eae) intimin [Intimin (VF0177) - Effector delivery system (VFC0086)] [Escherichia coli O127:H6 str. E2348/69]
|
|
LPS
|
gluP
|
0.0001226 |
17 |
VF0056
|
Immune modulation |
(rfbD) GDP-D-mannose dehydratase [LPS (VF0056) - Immune modulation (VFC0258)] [Helicobacter pylori 26695]
|
|
MprAB
|
mprB
|
0.0000649 |
8 |
VF0298
|
Regulation |
(mprA) two-component response regulator MrpA [MprAB (VF0298) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
HspR
|
hspR
|
0.0000072 |
1 |
VF0297
|
Regulation |
(hspR) heat shock protein transcriptional repressor HspR [HspR (VF0297) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
Mycobactin
|
mbtB
|
0.0001947 |
12 |
VF0299
|
Nutritional/Metabolic factor |
(mbtD) Polyketide synthetase MbtD (polyketide synthase) [Mycobactin (VF0299) - Nutritional/Metabolic factor (VFC0272)] [Mycobacterium tuberculosis H37Rv]
|
|
CcmC
|
ccmF
|
0.0010455 |
137 |
VF0292
|
Nutritional/Metabolic factor |
(ccmF) cytochrome c heme lyase subunit CcmF [CcmC (VF0292) - Nutritional/Metabolic factor (VFC0272)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Urease
|
ureG
|
0.6790687 |
39,538 |
VF0050
|
Stress survival |
(ureG) urease accessory protein (ureG) [Urease (VF0050) - Stress survival (VFC0282)] [Helicobacter pylori 26695]
|
|
LPS
|
rfbC
|
0.0957263 |
13,250 |
VF0171
|
Immune modulation |
(LPG_RS03855) glycosyltransferase family 2 protein [LPS (VF0171) - Immune modulation (VFC0258)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
TTSS secreted effectors
|
yopJ/yopP
|
0.0002379 |
31 |
VF1021
|
Effector delivery system |
(yopJ/yopP) type III secretion system effector YopP/YopJ, acetyltransferase [TTSS secreted effectors (VF1021) - Effector delivery system (VFC0086)] [Yersinia pestis CO92]
|
|
EspC
|
espC
|
0.0256188 |
2,973 |
VF0173
|
Effector delivery system |
(espC) Type III secretion system secreted protein, serine protease [EspC (VF0173) - Effector delivery system (VFC0086)] [Escherichia coli O127:H6 str. E2348/69]
|
|
SigF
|
sigF
|
0.0000072 |
1 |
VF0294
|
Regulation |
(sigF) RNA polymerase sigma factor SigF [SigF (VF0294) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
TTSS
|
escD
|
2.5338712 |
27,102 |
VF0172
|
Effector delivery system |
(cesD2) chaperone for EspD [TTSS (VF0172) - Effector delivery system (VFC0086)] [Escherichia coli O127:H6 str. E2348/69]
|
|
Flagella
|
tlpB
|
0.0000721 |
10 |
VF0051
|
Motility |
(cheV3) chemotaxis coupling protein CheV3 [Flagella (VF0051) - Motility (VFC0204)] [Helicobacter pylori 26695]
|
|
IraAB
|
iraA
|
0.0000072 |
1 |
VF0293
|
Nutritional/Metabolic factor |
(iraA) Small-molecule methyltransferase IraA [IraAB (VF0293) - Nutritional/Metabolic factor (VFC0272)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Lymphostatin/LifA
|
lifA/efa1
|
0.2755269 |
30,066 |
VF0175
|
Effector delivery system |
(lifA/efa1) lymphostatin Efa1/LifA [Lymphostatin/LifA (VF0175) - Effector delivery system (VFC0086)] [Escherichia coli O55:H7 str. CB9615]
|
|
SigH
|
sigH
|
0.0000144 |
2 |
VF0296
|
Regulation |
(sigH) ECF RNA polymerase sigma factor SigH [SigH (VF0296) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
BFP
|
bfpU
|
0.0908665 |
2,193 |
VF0174
|
Adherence |
(bfpP) prepilin peptidase BfpP [BFP (VF0174) - Adherence (VFC0001)] [Escherichia coli O127:H6 str. E2348/69]
|
|
SigE
|
sigE
|
0.0000144 |
2 |
VF0295
|
Regulation |
(sigE) ECF RNA polymerase sigma factor SigE [SigE (VF0295) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
Sulfolipid-1 biosynthesis and transport
|
papA1
|
0.0001226 |
4 |
VF0803
|
Immune modulation |
(papA2) trehalose-2-sulfate acyltransferase [Sulfolipid-1 biosynthesis and transport (VF0803) - Immune modulation (VFC0258)] [Mycobacterium tuberculosis H37Rv]
|
|
HSI-2 T6SS secreted effectors
|
pldA/tle5a
|
0.0000865 |
10 |
VF0915
|
Effector delivery system |
(pldA/tle5a) phospholipase D [HSI-2 T6SS secreted effectors (VF0915) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
HSI-3
|
tssK
|
0.0006129 |
64 |
VF0944
|
Effector delivery system |
(tssI) type VI secretion system tip protein VgrG [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
HSI-2
|
tssJ
|
0.0005336 |
44 |
VF0943
|
Effector delivery system |
(PA1663) transcriptional regulator [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
TTSS effectors secreted via both systems
|
slrP
|
0.0003173 |
43 |
VF0948
|
Effector delivery system |
(spvC) type III secretion system effector SpvC, phosphothreonine lyase [TTSS effectors secreted via both systems (VF0948) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
TTSS-2 secreted effectors
|
sspH2
|
0.0035548 |
487 |
VF0947
|
Effector delivery system |
(sseK2) type III secretion system effector SseK2 [TTSS-2 secreted effectors (VF0947) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
TTSS-1 secreted effectors
|
sipA/sspA
|
0.0001442 |
14 |
VF0949
|
Effector delivery system |
(sopD) type III secretion system effector SopD [TTSS-1 secreted effectors (VF0949) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Type IV pili
|
pilS
|
0.0005696 |
71 |
VF0401
|
Adherence |
(pilR) type IV pilus biosynthesis protein PilR [Type IV pili (VF0401) - Adherence (VFC0001)] [Yersinia pseudotuberculosis IP 31758]
|
|
BtpB
|
btpB
|
0.0000072 |
1 |
VF0522
|
Immune modulation |
(btpB) Tir domain containing protein BtpB [BtpB (VF0522) - Immune modulation (VFC0258)] [Brucella suis 1330]
|
|
ESX-3
|
PE5
|
0.0000865 |
5 |
VF0521
|
Effector delivery system |
(eccA3) Type VII secretion system protein EccA3 [ESX-3 (VF0521) - Effector delivery system (VFC0086)] [Mycobacterium tuberculosis H37Rv]
|
|
SinH
|
sinH
|
0.2878929 |
37,487 |
VF0400
|
Adherence |
(sinH) intimin-like protein [SinH (VF0400) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Type VII secretion system
|
esaB
|
0.0011825 |
68 |
VF0403
|
Effector delivery system |
(esaB) type VII secretion system protein EsaB [Type VII secretion system (VF0403) - Effector delivery system (VFC0086)] [Staphylococcus aureus subsp. aureus MW2]
|
|
PavB
|
pavB/pfbB
|
0.0000361 |
5 |
VF0524
|
Adherence |
(pavB/pfbB) cell wall surface anchor family protein, Plasminogen- and Fibronectin-binding protein B [PavB (VF0524) - Adherence (VFC0001)] [Streptococcus pneumoniae R6]
|
|
ESX-5
|
PPE25
|
0.0002524 |
9 |
VF0402
|
Effector delivery system |
(PPE25) PPE family protein PPE25 [ESX-5 (VF0402) - Effector delivery system (VFC0086)] [Mycobacterium tuberculosis H37Rv]
|
|
SpaP
|
spaP/pac
|
0.0000072 |
1 |
VF0526
|
Adherence |
(spaP/pac) cell surface antigen SpaP [SpaP (VF0526) - Adherence (VFC0001)] [Streptococcus mutans UA159]
|
|
ECP
|
ykgK/ecpR
|
5.7156979 |
125,621 |
VF0404
|
Adherence |
(ykgK/ecpR) regulator protein EcpR [ECP (VF0404) - Adherence (VFC0001)] [Escherichia coli O157:H7 str. EDL933]
|
|
Typhoid toxin
|
cdtB
|
0.0089843 |
1,244 |
VF0407
|
Exotoxin |
(pltC) an orphan pertussis-like toxin delivery subunit [Typhoid toxin (VF0407) - Exotoxin (VFC0235)] [Salmonella enterica subsp. enterica serovar Typhi str. CT18]
|
|
AI-2
|
luxS
|
0.9997981 |
138,579 |
VF0406
|
Biofilm |
(luxS) S-ribosylhomocysteinase [AI-2 (VF0406) - Biofilm (VFC0271)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
SSLs
|
set24
|
0.0004975 |
31 |
VF0990
|
Exotoxin |
(set19) superantigen-like protein SSL4 [SSLs (VF0990) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus MW2]
|
|
IlpA
|
IlpA
|
1.0007066 |
138,622 |
VF0513
|
Adherence |
(IlpA) immunogenic lipoprotein A [IlpA (VF0513) - Adherence (VFC0001)] [Vibrio vulnificus YJ016]
|
|
VAS T6SS secreted effectors
|
vgrG-3
|
0.0000288 |
4 |
VF0634
|
Effector delivery system |
(vgrG-3) type VI secretion system effector VgrG-3 protein, lysozyme-like activity, VgrG-3 and TsaB are a toxin-antitoxin complex [VAS T6SS secreted effectors (VF0634) - Effector delivery system (VFC0086)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
MAM7
|
mam7
|
0.0000144 |
2 |
VF0512
|
Adherence |
(mam7) multivalent adhesion molecule MAM7 [MAM7 (VF0512) - Adherence (VFC0001)] [Vibrio parahaemolyticus RIMD 2210633]
|
|
MSHA pili
|
mshE
|
0.0000433 |
4 |
VF0515
|
Adherence |
(mshL) MSHA biogenesis protein MshL [MSHA pili (VF0515) - Adherence (VFC0001)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
HemO cluster
|
ACICU_RS04565
|
0.0001082 |
8 |
VF0636
|
Nutritional/Metabolic factor |
(ACICU_RS04580) TonB-dependent receptor [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU]
|
|
Yst1 T2SS
|
yst1F
|
0.0011248 |
153 |
VF0635
|
Effector delivery system |
(yst1E) type II secretion system ATPase GspE [Yst1 T2SS (VF0635) - Effector delivery system (VFC0086)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
FlpA
|
Cj1279c
|
0.0000288 |
4 |
VF0637
|
Adherence |
(Cj1279c) fibronectin domain-containing lipoprotein [FlpA (VF0637) - Adherence (VFC0001)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
|
|
VCC
|
hlyA
|
0.0000072 |
1 |
VF0516
|
Exotoxin |
(hlyA) Vibrio cholerae cytolysin VCC [VCC (VF0516) - Exotoxin (VFC0235)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
Flagella
|
motB
|
0.0003605 |
40 |
VF0519
|
Motility |
(flgI) flagellar P-ring protein precursor FlgI [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
SgrA
|
sgrA
|
0.0000072 |
1 |
VF0540
|
Adherence |
(sgrA) cell wall anchored protein SgrA [SgrA (VF0540) - Adherence (VFC0001)] [Enterococcus faecium DO]
|
|
IdeR
|
ideR
|
0.0000144 |
2 |
VF0300
|
Regulation |
(ideR) Iron-dependent repressor and activator IdeR [IdeR (VF0300) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
Staphylocoagulase
|
coa
|
0.0000865 |
12 |
VF0421
|
Exoenzyme |
(coa) staphylocoagulase precursor [Staphylocoagulase (VF0421) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus MW2]
|
|
LPS
|
wbtL
|
1.4946967 |
138,643 |
VF0542
|
Immune modulation |
(wbtI) DegT/DnrJ/EryC1/StrS family aminotransferase [LPS (VF0542) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
VWbp
|
vWbp
|
0.0001226 |
16 |
VF0420
|
Exoenzyme |
(vWbp) secreted von Willebrand factor-binding protein precursor [VWbp (VF0420) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus str. Newman]
|
|
Nitrate reductase
|
narI
|
0.0184516 |
2,314 |
VF0302
|
Nutritional/Metabolic factor |
(narG) nitrate reductase subunit alpha [Nitrate reductase (VF0302) - Nutritional/Metabolic factor (VFC0272)] [Mycobacterium tuberculosis H37Rv]
|
|
Sbi
|
sbi
|
0.0000577 |
8 |
VF0423
|
Immune modulation |
(sbi) IgG-binding protein SBI [Sbi (VF0423) - Immune modulation (VFC0258)] [Staphylococcus aureus subsp. aureus MW2]
|
|
T6SS
|
pdpA
|
0.0000072 |
1 |
VF0544
|
Effector delivery system |
(pdpA) Type VI secretion system spike complex protein [T6SS (VF0544) - Effector delivery system (VFC0086)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
AdsA
|
adsA
|
0.0002668 |
28 |
VF0422
|
Immune modulation |
(adsA) Adenosine synthase A [AdsA (VF0422) - Immune modulation (VFC0258)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Capsule
|
FTT_RS04145
|
1.0003605 |
138,598 |
VF0543
|
Immune modulation |
(FTT_RS04150) glycosyltransferase family 1 protein [Capsule (VF0543) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
HspX
|
hspX
|
0.0000072 |
1 |
VF0301
|
Stress survival |
(hspX) Heat shock protein HspX (alpha-crystallin homolog) (14 kDa antigen) (HSP16.3) [HspX (VF0301) - Stress survival (VFC0282)] [Mycobacterium tuberculosis H37Rv]
|
|
SodA
|
sodA
|
0.0000216 |
3 |
VF0304
|
Stress survival |
(sodA) superoxide dismutase [SodA (VF0304) - Stress survival (VFC0282)] [Mycobacterium tuberculosis H37Rv]
|
|
SCIN
|
scn
|
0.0000216 |
3 |
VF0425
|
Immune modulation |
(scn) complement inhibitor SCIN [SCIN (VF0425) - Immune modulation (VFC0258)] [Staphylococcus aureus subsp. aureus MW2]
|
|
KatG
|
katG
|
0.000411 |
55 |
VF0303
|
Stress survival |
(katG) catalase-peroxidase [KatG (VF0303) - Stress survival (VFC0282)] [Mycobacterium tuberculosis H37Rv]
|
|
CHIPS
|
chp
|
0.0000072 |
1 |
VF0424
|
Immune modulation |
(chp) chemotaxis-inhibiting protein CHIPS [CHIPS (VF0424) - Immune modulation (VFC0258)] [Staphylococcus aureus subsp. aureus str. Newman]
|
|
AhpC
|
ahpC
|
0.0000144 |
2 |
VF0306
|
Stress survival |
(ahpC) alkyl hydroperoxide reductase subunit AhpC [AhpC (VF0306) - Stress survival (VFC0282)] [Mycobacterium tuberculosis H37Rv]
|
|
T6SS-1
|
BPS_RS26875
|
0.0000144 |
2 |
VF0429
|
Effector delivery system |
(BPS_RS26875) response regulator VirG [T6SS-1 (VF0429) - Effector delivery system (VFC0086)] [Burkholderia pseudomallei K96243]
|
|
Bsa T3SS
|
bsaZ
|
0.0011465 |
159 |
VF0428
|
Effector delivery system |
(bsaQ) Type III secretion system protein BsaQ [Bsa T3SS (VF0428) - Effector delivery system (VFC0086)] [Burkholderia pseudomallei K96243]
|
|
LipF
|
lipF
|
0.0000288 |
3 |
VF0307
|
Nutritional/Metabolic factor |
(lipF) Probable esterase/lipase LipF [LipF (VF0307) - Nutritional/Metabolic factor (VFC0272)] [Mycobacterium tuberculosis H37Rv]
|
|
PDIM
|
pks15
|
0.0006345 |
15 |
VF0309
|
Immune modulation |
(Rv2951c) phthiodiolone/phenolphthiodiolone dimycocerosates ketoreductase [PDIM (VF0309) - Immune modulation (VFC0258)] [Mycobacterium tuberculosis H37Rv]
|
|
Nhe
|
nheB
|
0.0000721 |
4 |
VF0533
|
Exotoxin |
(nheC) non-hemolytic enterotoxin C [Nhe (VF0533) - Exotoxin (VFC0235)] [Bacillus cereus ATCC 10987]
|
|
HBL
|
hblD
|
0.0000072 |
1 |
VF0532
|
Exotoxin |
(hblD) Hemolysin BL lytic component L1 [HBL (VF0532) - Exotoxin (VFC0235)] [Bacillus cereus ATCC 14579]
|
|
CytK
|
cytK
|
0.0000072 |
1 |
VF0535
|
Exotoxin |
(cytK) cytotoxin K [CytK (VF0535) - Exotoxin (VFC0235)] [Bacillus cereus ATCC 10987]
|
|
TcpC
|
tcpC
|
0.0345959 |
4,600 |
VF0413
|
Immune modulation |
(tcpC) Tir domain containing protein TcpC [TcpC (VF0413) - Immune modulation (VFC0258)] [Escherichia coli CFT073]
|
|
ALO
|
alo
|
0.0000216 |
3 |
VF0534
|
Exotoxin |
(alo) thiol-activated cytolysin [ALO (VF0534) - Exotoxin (VFC0235)] [Bacillus anthracis str. Sterne]
|
|
RTX protein
|
frpC
|
0.0000072 |
1 |
VF0897
|
Adherence |
(frpC) iron-regulated protein FrpC [RTX protein (VF0897) - Adherence (VFC0001)] [Neisseria meningitidis MC58]
|
|
InhA
|
BAS_RS06430
|
0.0000937 |
7 |
VF0536
|
Exoenzyme |
(inhA) immune inhibitor A metalloprotease [InhA (VF0536) - Exoenzyme (VFC0251)] [Bacillus anthracis str. Sterne]
|
|
EcbA
|
ecbA/fss3
|
0.0000288 |
4 |
VF0539
|
Adherence |
(ecbA/fss3) Collagen binding MSCRAMM, EcbA/Fss3 [EcbA (VF0539) - Adherence (VFC0001)] [Enterococcus faecium DO]
|
|
Ebp pili
|
ebpB
|
0.0000937 |
8 |
VF0538
|
Adherence |
(srtC) sortase [Ebp pili (VF0538) - Adherence (VFC0001)] [Enterococcus faecalis V583]
|
|
DIP0733
|
DIP_RS14950
|
0.0000216 |
3 |
VF0601
|
Adherence |
(DIP_RS14950) UPF0182 family protein [DIP0733 (VF0601) - Adherence (VFC0001)] [Corynebacterium diphtheriae NCTC 13129]
|
|
T4P
|
pilS
|
0.0140604 |
1,874 |
VF0966
|
Invasion |
(pilQ) Flp pilus assembly complex ATPase component TadA [T4P (VF0966) - Invasion (VFC0083)] [Salmonella enterica subsp. enterica serovar Typhi str. CT18]
|
|
PagN
|
pagN
|
0.0000288 |
3 |
VF0968
|
Invasion |
(pagN) outer membrane adhesin/invasin protein [PagN (VF0968) - Invasion (VFC0083)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
ChiRP
|
pilC
|
0.0001154 |
14 |
VF0609
|
Adherence |
(pilC) type II secretion system F family protein [ChiRP (VF0609) - Adherence (VFC0001)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
TTSS secreted effectors
|
CT_163
|
0.0002884 |
2 |
VF0711
|
Effector delivery system |
(CT_429) hypothetical protein [TTSS secreted effectors (VF0711) - Effector delivery system (VFC0086)] [Chlamydia trachomatis D/UW-3/CX]
|
|
NanH/VCNA
|
nanH
|
0.0000216 |
3 |
VF0621
|
Exoenzyme |
(nanH) sialidase [NanH/VCNA (VF0621) - Exoenzyme (VFC0251)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
YplA
|
yplA
|
0.0000144 |
2 |
VF0622
|
Exotoxin |
(yplA) DUF2974 domain-containing protein [YplA (VF0622) - Exotoxin (VFC0235)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
AdeFGH efflux pump
|
adeG
|
0.0196269 |
2,178 |
VF0504
|
Biofilm |
(adeH) outer membrane protein [AdeFGH efflux pump (VF0504) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU]
|
|
FdeC
|
fdeC
|
1.0715712 |
129,377 |
VF0506
|
Adherence |
(fdeC) adhesin FdeC [FdeC (VF0506) - Adherence (VFC0001)] [Escherichia coli O45:K1:H7 str. S88]
|
|
YapK
|
yapK
|
0.0003822 |
53 |
VF0508
|
Adherence |
(yapK) autotransporter protein YapK [YapK (VF0508) - Adherence (VFC0001)] [Yersinia pestis CO92]
|
|
YapV
|
yapV
|
0.0001442 |
20 |
VF0507
|
Adherence |
(yapV) autotransporter protein YapV [YapV (VF0507) - Adherence (VFC0001)] [Yersinia pestis KIM 10]
|
|
YapJ
|
yapJ
|
0.0001947 |
27 |
VF0509
|
Adherence |
(yapJ) autotransporter protein YapJ [YapJ (VF0509) - Adherence (VFC0001)] [Yersinia pestis CO92]
|
|
BapA
|
bapA
|
0.0002379 |
24 |
VF0971
|
Adherence |
|
|
SiiE
|
siiE
|
0.0004038 |
41 |
VF0970
|
Adherence |
(siiE) non-fimbrial adhesin SiiE [SiiE (VF0970) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Flp pili
|
VV1_RS15610
|
0.0000505 |
7 |
VF0612
|
Adherence |
(VV1_RS15610) CpaF family protein [Flp pili (VF0612) - Adherence (VFC0001)] [Vibrio vulnificus CMCP6]
|
|
SCI (Salmonella centrisome island)/SPI-6 T6SS
|
STM0278
|
0.5333881 |
8,336 |
VF0974
|
Effector delivery system |
|
|
TTSS secreted effectors
|
exoY
|
0.0000649 |
7 |
VF0853
|
Effector delivery system |
(exoT) type III secretion system effector ExoT, ADP ribosyltransferase activity and GTPase-activating protein activity [TTSS secreted effectors (VF0853) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
Eps T2SS
|
epsG
|
0.0085516 |
1,182 |
VF0613
|
Effector delivery system |
(epsI) type II secretion system minor pseudopilin GspI [Eps T2SS (VF0613) - Effector delivery system (VFC0086)] [Vibrio cholerae O395]
|
|
VirF
|
virF
|
0.0142912 |
1,982 |
VF0979
|
Regulation |
(virF) transcriptional activator VirF [VirF (VF0979) - Regulation (VFC0301)] [Shigella flexneri 2a str. 301]
|
|
TTSS secreted effectors
|
ipaJ
|
0.5462949 |
12,677 |
VF0978
|
Effector delivery system |
(ospG) type III secretion system effector OspG, protein kinase [TTSS secreted effectors (VF0978) - Effector delivery system (VFC0086)] [Shigella flexneri 2a str. 301]
|
|
Bap1
|
VC_RS09110
|
0.0000072 |
1 |
VF0618
|
Biofilm |
(VC_RS09110) hemolysin [Bap1 (VF0618) - Biofilm (VFC0271)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
GbpA
|
gbpA
|
0.0000144 |
2 |
VF0619
|
Adherence |
(gbpA) N-acetylglucosamine-binding protein GbpA [GbpA (VF0619) - Adherence (VFC0001)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|