|
IcsP (SopA)
|
icsP/sopA
|
0.9112464 |
7,171 |
VF0122
|
Exoenzyme |
(icsP/sopA) outer membrane protease of the OmpP family, involved in cleavage of surface exposed IcsA [IcsP (SopA) (VF0122) - Exoenzyme (VFC0251)] [Shigella flexneri 2a str. 301]
|
|
IcsA (VirG)
|
icsA/virG
|
0.907189 |
7,108 |
VF0121
|
Motility |
(icsA/virG) autotransporter, actin tail assembly protein IcsA/VirG [IcsA (VirG) (VF0121) - Motility (VFC0204)] [Shigella flexneri 2a str. 301]
|
|
LPS
|
gtr
|
1.7934576 |
7,359 |
VF0124
|
Immune modulation |
(gtr) glucosyl tranferase [LPS (VF0124) - Immune modulation (VFC0258)] [Shigella flexneri 2a str. 301]
|
|
Capsule
|
cap8O
|
0.0013947 |
7 |
VF0003
|
Immune modulation |
(cap8D) type 8 capsular polysaccharide synthesis protein Cap8D [Capsule (VF0003) - Immune modulation (VFC0258)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Aerobactin
|
iutA
|
4.946621 |
7,819 |
VF0123
|
Nutritional/Metabolic factor |
(iucC) aerobactin synthesis protein IucC [Aerobactin (VF0123) - Nutritional/Metabolic factor (VFC0272)] [Shigella flexneri 2a str. 301]
|
|
Type I pili
|
fimC
|
0.0008875 |
7 |
VF0486
|
Adherence |
(fimC) outer membrane usher protein [Type I pili (VF0486) - Adherence (VFC0001)] [Aeromonas hydrophila ML09-119]
|
|
LPS
|
acpXL
|
0.9996196 |
7,884 |
VF0367
|
Immune modulation |
(acpXL) acyl carrier protein [LPS (VF0367) - Immune modulation (VFC0258)] [Brucella melitensis bv. 1 str. 16M]
|
|
SinH
|
sinH
|
0.0010143 |
7 |
VF0400
|
Adherence |
(sinH) intimin-like protein [SinH (VF0400) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Type VII secretion system
|
essC
|
0.0005072 |
2 |
VF0403
|
Effector delivery system |
(esaG) TIGR01741 family protein [Type VII secretion system (VF0403) - Effector delivery system (VFC0086)] [Staphylococcus aureus subsp. aureus MW2]
|
|
PavB
|
pavB/pfbB
|
0.0001268 |
1 |
VF0524
|
Adherence |
(pavB/pfbB) cell wall surface anchor family protein, Plasminogen- and Fibronectin-binding protein B [PavB (VF0524) - Adherence (VFC0001)] [Streptococcus pneumoniae R6]
|
|
PfbA
|
pfbA
|
0.0002536 |
1 |
VF0525
|
Adherence |
(pfbA) cell wall surface anchor family protein, Plasminogen- and Fibronectin-binding protein A [PfbA (VF0525) - Adherence (VFC0001)] [Streptococcus pneumoniae R6]
|
|
ECP
|
ykgK/ecpR
|
0.2454672 |
267 |
VF0404
|
Adherence |
(ykgK/ecpR) regulator protein EcpR [ECP (VF0404) - Adherence (VFC0001)] [Escherichia coli O157:H7 str. EDL933]
|
|
AI-2
|
luxS
|
1 |
7,884 |
VF0406
|
Biofilm |
(luxS) S-ribosylhomocysteinase [AI-2 (VF0406) - Biofilm (VFC0271)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
IgA1 protease
|
iga
|
0.0001268 |
1 |
VF0080
|
Effector delivery system |
(iga) IgA-specific serine endopeptidase [IgA1 protease (VF0080) - Effector delivery system (VFC0086)] [Neisseria meningitidis MC58]
|
|
Type IV pili
|
vfr
|
0.9998732 |
7,886 |
VF0082
|
Adherence |
(vfr) cAMP-regulatory protein [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1]
|
|
LPS
|
waaG
|
0.0007607 |
6 |
VF0085
|
Immune modulation |
(waaA) lipopolysaccharide core biosynthesis protein WaaP [LPS (VF0085) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1]
|
|
T6SS
|
vipB
|
0.0207937 |
71 |
VF0480
|
Effector delivery system |
(vasK/icmF) Type VI secretion system protein [T6SS (VF0480) - Effector delivery system (VFC0086)] [Aeromonas hydrophila subsp. hydrophila ATCC 7966]
|
|
TraJ
|
AAA92657
|
0.0890072 |
702 |
VF0241
|
Invasion |
(AAA92657) unknown protein [TraJ (VF0241) - Invasion (VFC0083)] [Escherichia coli]
|
|
Pic
|
pic
|
0.5070369 |
3,927 |
VF0120
|
Exoenzyme |
(pic) serine protease, autotransporter Pic [Pic (VF0120) - Exoenzyme (VFC0251)] [Shigella flexneri 2a str. 301]
|
|
Capsule
|
cpsB/cdsA
|
0.0002536 |
2 |
VF0361
|
Immune modulation |
(cpsB/cdsA) phosphatidate cytidylyltransferase [Capsule (VF0361) - Immune modulation (VFC0258)] [Enterococcus faecalis V583]
|
|
Pic
|
pic
|
0.0021554 |
16 |
VF0232
|
Effector delivery system |
(pic) Pic serine protease precursor, autotransporter [Pic (VF0232) - Effector delivery system (VFC0086)] [Escherichia coli CFT073]
|
|
LOS
|
rfaC
|
0.0002536 |
2 |
VF0078
|
Immune modulation |
(rfaC) lipopolysaccharide heptosyltransferase I [LOS (VF0078) - Immune modulation (VFC0258)] [Neisseria meningitidis MC58]
|
|
PhoPQ
|
phoP
|
2.0003804 |
7,884 |
VF0111
|
Regulation |
(phoP) response regulator in two-component regulatory system with PhoQ [PhoPQ (VF0111) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Lateral flagella
|
lfhA
|
0.0103969 |
80 |
VF0474
|
Motility |
(lfiI) lateral flagellar FliI-like assembly ATPase [Lateral flagella (VF0474) - Motility (VFC0204)] [Aeromonas salmonicida subsp. salmonicida A449]
|
|
Polar flagella
|
nueA
|
2.0016483 |
7,885 |
VF0473
|
Motility |
(flrA) FleQ protein [Polar flagella (VF0473) - Motility (VFC0204)] [Aeromonas hydrophila ML09-119]
|
|
Sat
|
sat
|
2.2703182 |
7,530 |
VF0231
|
Effector delivery system |
(sat) Aecreted auto transpoter toxin [Sat (VF0231) - Effector delivery system (VFC0086)] [Escherichia coli CFT073]
|
|
Fur
|
fur
|
1.0003804 |
7,886 |
VF0113
|
Regulation |
(fur) ferric iron uptake transcriptional regulator [Fur (VF0113) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Chu
|
chuX
|
0.0010143 |
3 |
VF0234
|
Nutritional/Metabolic factor |
(chuY) ChuY [Chu (VF0234) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli O157:H7 str. EDL933]
|
|
Tsh
|
tsh
|
0.0010143 |
7 |
VF0233
|
Effector delivery system |
(tsh) temperature-sensitive protein Tsh [Tsh (VF0233) - Effector delivery system (VFC0086)] [Escherichia coli O25b:H4-ST131]
|
|
RpoS
|
rpoS
|
1.0107772 |
7,874 |
VF0112
|
Regulation |
(rpoS) RNA polymerase sigma factor RpoS [RpoS (VF0112) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Exe T2SS
|
exeG
|
0.0105236 |
63 |
VF0478
|
Effector delivery system |
(exeD) general secretion pathway protein D [Exe T2SS (VF0478) - Effector delivery system (VFC0086)] [Aeromonas hydrophila ML09-119]
|
|
OmpA
|
ompA
|
1.0002536 |
7,885 |
VF0236
|
Invasion |
(ompA) outer membrane protein A [OmpA (VF0236) - Invasion (VFC0083)] [Escherichia coli O18:K1:H7 str. RS218]
|
|
Shiga toxin
|
stxA
|
0.0182579 |
55 |
VF0117
|
Exotoxin |
(stxB) Shiga toxin subunit B precursor [Shiga toxin (VF0117) - Exotoxin (VFC0235)] [Shigella dysenteriae Sd197]
|
|
AslA
|
aslA
|
0.2112337 |
1,666 |
VF0238
|
Invasion |
(aslA) putative arylsulfatase [AslA (VF0238) - Invasion (VFC0083)] [Escherichia coli O18:K1:H7 str. RS218]
|
|
IlpA
|
IlpA
|
0.9997464 |
7,885 |
VF0513
|
Adherence |
(IlpA) immunogenic lipoprotein A [IlpA (VF0513) - Adherence (VFC0001)] [Vibrio vulnificus YJ016]
|
|
Ibes
|
ibeC
|
2.2410295 |
7,887 |
VF0237
|
Invasion |
(ibeB) Cu(+)/Ag(+) efflux RND transporter outer membrane channel CusC [Ibes (VF0237) - Invasion (VFC0083)] [Escherichia coli O45:K1:H7 str. S88]
|
|
TTSS (SPI-1 encode)
|
prgI
|
0.0150881 |
45 |
VF0116
|
Effector delivery system |
(prgH) type III secretion system outer MS ring protein PrgH [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
SigA
|
sigA
|
0.5365792 |
4,170 |
VF0119
|
Exoenzyme |
(sigA) serine protease, autotransporter SigA [SigA (VF0119) - Exoenzyme (VFC0251)] [Shigella flexneri 2a str. 301]
|
|
TTSS
|
spa15
|
25.7215671 |
7,057 |
VF0118
|
Effector delivery system |
(spa32) type III secretion system needle length regulator Spa32 [TTSS (VF0118) - Effector delivery system (VFC0086)] [Shigella flexneri 2a str. 301]
|
|
K1 capsule
|
kpsD
|
0.0121719 |
12 |
VF0239
|
Invasion |
(kpsD) Polysialic acid transport protein precursor [K1 capsule (VF0239) - Invasion (VFC0083)] [Escherichia coli O45:K1:H7 str. S88]
|
|
TTSS
|
glrA
|
0.0087486 |
5 |
VF0191
|
Effector delivery system |
(escN) ATPase EscN [TTSS (VF0191) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933]
|
|
ClpC
|
clpC
|
0.0012679 |
10 |
VF0072
|
Stress survival |
(clpC) endopeptidase Clp ATP-binding chain C [ClpC (VF0072) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
|
|
ClpP
|
clpP
|
1 |
7,886 |
VF0074
|
Stress survival |
(clpP) ATP-dependent Clp protease proteolytic subunit [ClpP (VF0074) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
|
|
Paa
|
paa
|
0.0005072 |
4 |
VF0194
|
Adherence |
(paa) outer membrane adhesin Paa [Paa (VF0194) - Adherence (VFC0001)] [Escherichia coli O157:H7 str. EDL933]
|
|
PNAG
|
pgaC
|
0.0059592 |
47 |
VF0472
|
Biofilm |
(pgaC) poly-beta-1,6 N-acetyl-D-glucosamine synthase [PNAG (VF0472) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU]
|
|
Salmochelin siderophore
|
iroN
|
0.0081146 |
14 |
VF0230
|
Nutritional/Metabolic factor |
(iroB) glucosyltransferase IroB [Salmochelin siderophore (VF0230) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073]
|
|
Type IV pili
|
pilT
|
0.0008875 |
7 |
VF0075
|
Adherence |
(pilE) Type IV pilus major pilin subunit PilE [Type IV pili (VF0075) - Adherence (VFC0001)] [Neisseria meningitidis MC58]
|
|
Capsule
|
cps4A
|
0.0005072 |
4 |
VF0144
|
Immune modulation |
(cps4I) capsular polysaccharide biosynthesis protein Cps4I [Capsule (VF0144) - Immune modulation (VFC0258)] [Streptococcus pneumoniae TIGR4]
|
|
PmrAB
|
pmrA
|
1.9994928 |
7,882 |
VF1355
|
Regulation |
(pmrB) sensory kinase PmrB [PmrAB (VF1355) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Autolysin
|
cbpD
|
0.0002536 |
1 |
VF0143
|
Exoenzyme |
(cbpD) choline binding protein D [Autolysin (VF0143) - Exoenzyme (VFC0251)] [Streptococcus pneumoniae TIGR4]
|
|
TTSS secreted effectors
|
espM1
|
0.8346646 |
5,801 |
VF1111
|
Effector delivery system |
(nleG2-2) DUF1076 domain-containing protein [TTSS secreted effectors (VF1111) - Effector delivery system (VFC0086)] [Escherichia coli O55:H7 str. CB9615]
|
|
LPS
|
wbtL
|
1.9906175 |
7,887 |
VF0542
|
Immune modulation |
(lpxA/glmU) UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase [LPS (VF0542) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
Vat
|
vat
|
0.0015215 |
11 |
VF1112
|
Effector delivery system |
(vat) vacuolating autotransporter toxin [Vat (VF1112) - Effector delivery system (VFC0086)] [Escherichia coli CFT073]
|
|
Nitrate reductase
|
narH
|
0.9516927 |
7,475 |
VF0302
|
Nutritional/Metabolic factor |
(narG) nitrate reductase subunit alpha [Nitrate reductase (VF0302) - Nutritional/Metabolic factor (VFC0272)] [Mycobacterium tuberculosis H37Rv]
|
|
Neuraminidase
|
nanB
|
0.0001268 |
1 |
VF0148
|
Exoenzyme |
(nanB) neuraminidase B [Neuraminidase (VF0148) - Exoenzyme (VFC0251)] [Streptococcus pneumoniae TIGR4]
|
|
IgA1 protease
|
zmpC
|
0.0001268 |
1 |
VF0147
|
Immune modulation |
(zmpC) immunoglobulin A1 protease [IgA1 protease (VF0147) - Immune modulation (VFC0258)] [Streptococcus pneumoniae TIGR4]
|
|
Capsule
|
rpe
|
1 |
7,887 |
VF0543
|
Immune modulation |
(rpe) ribulose-phosphate 3-epimerase [Capsule (VF0543) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
PDIM
|
ppsD
|
0.0001268 |
1 |
VF0309
|
Immune modulation |
(ppsD) phthiocerol synthesis polyketide synthase type I PpsD [PDIM (VF0309) - Immune modulation (VFC0258)] [Mycobacterium tuberculosis H37Rv]
|
|
TTSS-2 secreted effectors
|
sspH2
|
0.0005072 |
2 |
VF0947
|
Effector delivery system |
(sseI/srfH) type III secretion system effector SseI/SrfH (SsrB regulated factor H), deamidase [TTSS-2 secreted effectors (VF0947) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
TTSS-1 secreted effectors
|
sopD
|
0.0002536 |
1 |
VF0949
|
Effector delivery system |
(sopD) type III secretion system effector SopD [TTSS-1 secreted effectors (VF0949) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
CsrA
|
csrA
|
1 |
7,883 |
VF0261
|
Regulation |
(csrA) carbon storage regulator CsrA [CsrA (VF0261) - Regulation (VFC0301)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
TTSS secreted effectors
|
cif
|
7.8339039 |
7,886 |
VF1110
|
Effector delivery system |
(espX4) Type III secretion system effector EspX4 [TTSS secreted effectors (VF1110) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933]
|
|
SCI T6SS secreted effectors
|
tae4
|
1.880563 |
5,327 |
VF1195
|
Effector delivery system |
(tae4) type VI secretion system effector tae4, L,D-endopeptidase [SCI T6SS secreted effectors (VF1195) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
LetA/S
|
letA
|
0.000634 |
5 |
VF0262
|
Regulation |
(letA) UvrY/SirA/GacA family response regulator transcription factor [LetA/S (VF0262) - Regulation (VFC0301)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
SE
|
seb
|
0.0001268 |
1 |
VF0020
|
Exotoxin |
(seb) staphylococcal enterotoxin B [SE (VF0020) - Exotoxin (VFC0235)] [Staphylococcus aureus S6]
|
|
Isocitrate lyase
|
icl
|
1 |
7,882 |
VF0253
|
Others |
(icl) Isocitrate lyase Icl (isocitrase) (isocitratase) [Isocitrate lyase (VF0253) - Others (VFC0346)] [Mycobacterium tuberculosis H37Rv]
|
|
Gamma-hemolysin
|
hlgA
|
0.0001268 |
1 |
VF0011
|
Exotoxin |
(hlgA) gamma-hemolysin chain II precursor [Gamma-hemolysin (VF0011) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Shu
|
shuA
|
0.0001268 |
1 |
VF0256
|
Nutritional/Metabolic factor |
(shuA) outer membrane heme/hemoglobin receptor ShuA [Shu (VF0256) - Nutritional/Metabolic factor (VFC0272)] [Shigella dysenteriae Sd197]
|
|
ShET2
|
senB
|
0.0488145 |
382 |
VF0258
|
Exotoxin |
(senB) enterotoxin [ShET2 (VF0258) - Exotoxin (VFC0235)] [Shigella boydii Sb227]
|
|
Isd
|
harA
|
0.0001268 |
1 |
VF0015
|
Nutritional/Metabolic factor |
(harA) haptoglobin-binding heme uptake protein HarA [Isd (VF0015) - Nutritional/Metabolic factor (VFC0272)] [Staphylococcus aureus subsp. aureus str. Newman]
|
|
SigA
|
sigA/rpoV
|
0.0002536 |
2 |
VF0257
|
Regulation |
(sigA/rpoV) RNA polymerase sigma factor SigA [SigA (VF0257) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
Yersiniabactin
|
ybtS
|
0.0262457 |
22 |
VF0136
|
Nutritional/Metabolic factor |
(irp1) yersiniabactin biosynthetic protein Irp1 [Yersiniabactin (VF0136) - Nutritional/Metabolic factor (VFC0272)] [Yersinia pestis CO92]
|
|
SpA
|
spa
|
0.0001268 |
1 |
VF0017
|
Exotoxin |
(spa) Immunoglobulin G binding protein A precursor [SpA (VF0017) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus MW2]
|
|
F1 antigen
|
caf1A
|
0.0002536 |
2 |
VF0138
|
Immune modulation |
(caf1A) F1 capsule anchoring protein [F1 antigen (VF0138) - Immune modulation (VFC0258)] [Yersinia pestis CO92]
|
|
SDr
|
sdrD
|
0.0002536 |
2 |
VF0019
|
Adherence |
(sdrD) Ser-Asp rich fibrinogen-binding bone sialoprotein-binding protein [SDr (VF0019) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Alginate
|
algU
|
1 |
7,886 |
VF0091
|
Biofilm |
(algU) alginate biosynthesis protein AlgZ/FimS [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1]
|
|
Quorum sensing
|
rhlR
|
0.0001268 |
1 |
VF0093
|
Biofilm |
(rhlR) transcriptional regulator RhlR [Quorum sensing (VF0093) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1]
|
|
Trw type IV secretion system
|
trwD
|
0.0001268 |
1 |
VF0372
|
Effector delivery system |
(trwD) Trw type IV secretion sysmtem VirB11 homolog, trwD protein [Trw type IV secretion system (VF0372) - Effector delivery system (VFC0086)] [Bartonella henselae str. Houston-1]
|
|
Ent
|
fepD
|
0.0003804 |
2 |
VF0562
|
Nutritional/Metabolic factor |
(fepD) iron-enterobactin transporter membrane protein [Ent (VF0562) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
LPS
|
rfbB
|
0.0020287 |
4 |
VF0561
|
Immune modulation |
(KP1_RS17230) glycosyltransferase [LPS (VF0561) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
LOS
|
rffG
|
12.9982249 |
7,887 |
VF0044
|
Immune modulation |
(msbA) lipid transporter ATP-binding/permease [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20]
|
|
KatAB
|
katA
|
0.0013947 |
11 |
VF0168
|
Stress survival |
(katA) catalase/(hydro)peroxidase [KatAB (VF0168) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Ybt
|
ybtU
|
0.005452 |
22 |
VF0564
|
Nutritional/Metabolic factor |
(fyuA) yersiniabactin receptor FyuA [Ybt (VF0564) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Sal
|
iroC
|
0.0001268 |
1 |
VF0563
|
Nutritional/Metabolic factor |
(iroC) ABC transporter [Sal (VF0563) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Tbp
|
tbpA
|
0.0002536 |
1 |
VF0046
|
Nutritional/Metabolic factor |
(tbpA) transferrin-binding protein A [Tbp (VF0046) - Nutritional/Metabolic factor (VFC0272)] [Neisseria meningitidis MC58]
|
|
Type I fimbriae
|
fimH
|
0.0116648 |
87 |
VF0566
|
Adherence |
(fimG) type 1 fimbrial minor component [Type I fimbriae (VF0566) - Adherence (VFC0001)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Lap
|
lap
|
0.0002536 |
2 |
VF0444
|
Adherence |
(lap) Listeria adhesion protein Lap [Lap (VF0444) - Adherence (VFC0001)] [Listeria monocytogenes EGD-e]
|
|
Capsule
|
glf
|
0.0010143 |
8 |
VF0323
|
Immune modulation |
(glf) UDP-galactopyranose mutase [Capsule (VF0323) - Immune modulation (VFC0258)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
|
|
Aerobactin
|
iutA
|
0.0044377 |
32 |
VF0565
|
Nutritional/Metabolic factor |
(iutA) ferric aerobactin receptor IutA [Aerobactin (VF0565) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Intimin
|
eae
|
0.0002536 |
2 |
VF0202
|
Effector delivery system |
(eae) intimin type gamma [Intimin (VF0202) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933]
|
|
SodB
|
sodB
|
1.0003804 |
7,885 |
VF0169
|
Stress survival |
(sodB) superoxide dismutase [SodB (VF0169) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
AcrAB
|
acrA
|
4.9386332 |
7,887 |
VF0568
|
Antimicrobial activity/Competitive advantage |
(acrB) acriflavine resistance protein B [AcrAB (VF0568) - Antimicrobial activity/Competitive advantage (VFC0325)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Type 3 fimbriae
|
mrkI
|
0.0035501 |
6 |
VF0567
|
Biofilm |
(mrkC) fimbrial biogenesis outer membrane usher protein mrkC precursor [Type 3 fimbriae (VF0567) - Biofilm (VFC0271)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Efa-1/LifA
|
lifA/efa1
|
0.0001268 |
1 |
VF0204
|
Effector delivery system |
(lifA/efa1) lymphostatin Efa1/LifA [Efa-1/LifA (VF0204) - Effector delivery system (VFC0086)] [Escherichia coli O103:H2 str. 12009]
|
|
Curli fibers
|
csgC
|
8.427539 |
7,787 |
VF1138
|
Adherence |
(csgB) curlin minor subunit CsgB [Curli fibers (VF1138) - Adherence (VFC0001)] [Escherichia coli O25b:H4-ST131]
|
|
Hemolysin
|
hlyA
|
0.0005072 |
1 |
VF0207
|
Exotoxin |
(hlyA) Hemolysin A [Hemolysin (VF0207) - Exotoxin (VFC0235)] [Escherichia coli O157:H7 str. EDL933]
|
|
T4P
|
pilV
|
0.0011411 |
9 |
VF0966
|
Invasion |
(pilQ) Flp pilus assembly complex ATPase component TadA [T4P (VF0966) - Invasion (VFC0083)] [Salmonella enterica subsp. enterica serovar Typhi str. CT18]
|
|
Stx
|
stx2B
|
0.0005072 |
1 |
VF0206
|
Exotoxin |
(stx2B) shiga-like toxin II B subunit encoded by bacteriophage BP-933W [Stx (VF0206) - Exotoxin (VFC0235)] [Escherichia coli O157:H7 str. EDL933]
|
|
T6SS
|
vipA/tssB
|
0.0081146 |
11 |
VF0569
|
Effector delivery system |
(vipB/tssC) type VI secretion system contractile sheath large subunit VipB [T6SS (VF0569) - Effector delivery system (VFC0086)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
StcE
|
stcE
|
0.0010143 |
8 |
VF0209
|
Exoenzyme |
(stcE) metalloprotease [StcE (VF0209) - Exoenzyme (VFC0251)] [Escherichia coli O157:H7 str. EDL933]
|
|
EspP
|
espP
|
0.0005072 |
4 |
VF0208
|
Effector delivery system |
(espP) autotransporter, serine protease [EspP (VF0208) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933]
|
|
ChiRP
|
pilA
|
0.0001268 |
1 |
VF0609
|
Adherence |
(pilA) pilin [ChiRP (VF0609) - Adherence (VFC0001)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
PavA
|
pavA
|
0.0002536 |
1 |
VF0283
|
Adherence |
(pavA) Fibronectin-binding protein-like protein A [PavA (VF0283) - Adherence (VFC0001)] [Streptococcus pneumoniae R6]
|
|
Capsule
|
rfbK1
|
11.3983771 |
7,886 |
VF0560
|
Immune modulation |
(KP1_RS17305) GDP-L-fucose synthase [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Flagella
|
tsr
|
0.011538 |
90 |
VF0430
|
Motility |
(tsr) methyl-accepting chemotaxis protein I [Flagella (VF0430) - Motility (VFC0204)] [Burkholderia pseudomallei K96243]
|
|
MisL
|
misL
|
0.0055788 |
23 |
VF0397
|
Adherence |
(misL) putative autotransporter [MisL (VF0397) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Flagella
|
fleQ
|
0.0013947 |
11 |
VF0157
|
Motility |
(fleQ) transcriptional regulator FleQ [Flagella (VF0157) - Motility (VFC0204)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
RatB
|
ratB
|
0.0003804 |
1 |
VF0399
|
Adherence |
(ratB) putative outer membrane protein [RatB (VF0399) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
GGT
|
ggt
|
0.0001268 |
1 |
VF0553
|
Nutritional/Metabolic factor |
(ggt) gamma-glutamyltranspeptidase [GGT (VF0553) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
Hsp60
|
htpB
|
1.0007607 |
7,886 |
VF0159
|
Adherence |
(htpB) Hsp60, 60K heat shock protein HtpB [Hsp60 (VF0159) - Adherence (VFC0001)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Capsule I
|
manC
|
0.0491949 |
388 |
VF0436
|
Immune modulation |
(manC) GDP-mannose pyrophosphorylase [Capsule I (VF0436) - Immune modulation (VFC0258)] [Burkholderia pseudomallei K96243]
|
|
Dot/Icm T4SS secreted effectors
|
LPG_RS14840
|
0.0001268 |
1 |
VF0798
|
Effector delivery system |
(LPG_RS14840) Dot/Icm type IV secretion system effector [Dot/Icm T4SS secreted effectors (VF0798) - Effector delivery system (VFC0086)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Pyrimidine biosynthesis
|
carB
|
0.0032966 |
24 |
VF0558
|
Nutritional/Metabolic factor |
(carB) carbamoyl phosphate synthase large subunit [Pyrimidine biosynthesis (VF0558) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
PanC/PanD
|
panD
|
0.0001268 |
1 |
VF0319
|
Nutritional/Metabolic factor |
(panD) aspartate 1-decarboxylase [PanC/PanD (VF0319) - Nutritional/Metabolic factor (VFC0272)] [Mycobacterium tuberculosis H37Rv]
|
|
PsaA
|
psaA
|
0.0001268 |
1 |
VF0151
|
Nutritional/Metabolic factor |
(psaA) manganese ABC transporter, manganese-binding adhesion liprotein [PsaA (VF0151) - Nutritional/Metabolic factor (VFC0272)] [Streptococcus pneumoniae TIGR4]
|
|
O-antigen
|
galE
|
0.2655002 |
2,083 |
VF0392
|
Immune modulation |
(galE) UDP-glucose 4-epimerase GalE [O-antigen (VF0392) - Immune modulation (VFC0258)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
Flagella
|
motB
|
32.7952327 |
7,886 |
VF0394
|
Motility |
(fliL) flagellar basal body protein FliL [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
Type 1 fimbriae
|
fimI
|
9.5891974 |
7,844 |
VF0221
|
Adherence |
(fimF) FimF protein precursor [Type 1 fimbriae (VF0221) - Adherence (VFC0001)] [Escherichia coli CFT073]
|
|
P fimbriae
|
papC
|
0.0051984 |
23 |
VF0220
|
Adherence |
(papA) P pilus major subunit PapA [P fimbriae (VF0220) - Adherence (VFC0001)] [Escherichia coli CFT073]
|
|
Type 1 fimbriae
|
fimH
|
2.8030937 |
7,803 |
VF0102
|
Adherence |
(fimZ) DNA-binding response regulator [Type 1 fimbriae (VF0102) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Capsule
|
pseI
|
0.0019019 |
12 |
VF0465
|
Immune modulation |
(pseC) UDP-4-amino-4, 6-dideoxy-N-acetyl-beta-L-altrosamine transaminase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU]
|
|
Dr adhesins
|
draC
|
0.0002536 |
2 |
VF0223
|
Adherence |
(draC) usher protein DraC [Dr adhesins (VF0223) - Adherence (VFC0001)] [Escherichia coli O75:K5:H- str. IH11128]
|
|
Ler
|
AAC38364
|
0.000634 |
5 |
VF0189
|
Regulation |
(AAC38364) Orf1 [Ler (VF0189) - Regulation (VFC0301)] [Escherichia coli O127:H6 str. E2348/69]
|
|
Vi antigen
|
tviC
|
0.0012679 |
10 |
VF0101
|
Immune modulation |
(tviC) Vi polysaccharide biosynthesis protein, UDP-GlcNAcA 4-epimerase TviC [Vi antigen (VF0101) - Immune modulation (VFC0258)] [Salmonella enterica subsp. enterica serovar Typhi str. CT18]
|
|
Pef
|
pefC
|
0.0002536 |
2 |
VF0104
|
Adherence |
(pefD) plasmid-encoded fimbriae chaperone protein PefD [Pef (VF0104) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Alpha-Hemolysin
|
hlyA
|
0.0020287 |
4 |
VF0225
|
Exotoxin |
(hlyC) Hemolysin C [Alpha-Hemolysin (VF0225) - Exotoxin (VFC0235)] [Escherichia coli CFT073]
|
|
F1C fimbriae
|
focC
|
0.0038037 |
30 |
VF0224
|
Adherence |
(focC) F1C periplasmic chaperone [F1C fimbriae (VF0224) - Adherence (VFC0001)] [Escherichia coli CFT073]
|
|
Agf
|
csgC
|
0.0120451 |
95 |
VF0103
|
Adherence |
(csgC) curli assembly protein CsgC [Agf (VF0103) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Chu
|
chuX
|
0.0065931 |
8 |
VF0227
|
Nutritional/Metabolic factor |
(chuT) periplasmic heme-binding protein ChuT [Chu (VF0227) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073]
|
|
MgtB
|
mgtB
|
0.0001268 |
1 |
VF0106
|
Nutritional/Metabolic factor |
(mgtB) Mg2+ transport protein [MgtB (VF0106) - Nutritional/Metabolic factor (VFC0272)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Lpf
|
lpfD
|
0.0058324 |
19 |
VF0105
|
Adherence |
(lpfE) long polar fimbrial minor subunit LpfE, adhesin [Lpf (VF0105) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
AdeFGH efflux pump
|
adeG
|
0.0007607 |
6 |
VF0504
|
Biofilm |
(adeG) cation/multidrug efflux pump [AdeFGH efflux pump (VF0504) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU]
|
|
Aerobactin
|
iutA
|
0.0143274 |
53 |
VF0229
|
Nutritional/Metabolic factor |
(iutA) ferric aerobactin receptor precusor IutA [Aerobactin (VF0229) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073]
|
|
Rck
|
rck
|
0.0005072 |
4 |
VF0108
|
Invasion |
(rck) resistance to complement killing [Rck (VF0108) - Invasion (VFC0083)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Enterobactin
|
entS
|
10.0213009 |
7,838 |
VF0228
|
Nutritional/Metabolic factor |
(entE) 2,3-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073]
|
|
FdeC
|
fdeC
|
0.0859642 |
275 |
VF0506
|
Adherence |
(fdeC) adhesin FdeC [FdeC (VF0506) - Adherence (VFC0001)] [Escherichia coli O45:K1:H7 str. S88]
|
|
SodCI
|
sodCI
|
0.0015215 |
12 |
VF0109
|
Stress survival |
(sodCI) Gifsy-2 prophage: superoxide dismutase precursor (Cu-Zn) [SodCI (VF0109) - Stress survival (VFC0282)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Type IV secretion system
|
virB9/cagX
|
0.0001268 |
1 |
VF0060
|
Effector delivery system |
(virB9/cagX) type IV secretion system protein Cag8/CagX, VirB9 homolog [Type IV secretion system (VF0060) - Effector delivery system (VFC0086)] [Helicobacter pylori 26695]
|
|
EF-Tu
|
tufA
|
3.1887917 |
7,886 |
VF0460
|
Adherence |
(tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
Colibactin
|
clbS
|
0.025485 |
101 |
VF0573
|
Exotoxin |
(clbS) colibactin self-protection protein ClbS [Colibactin (VF0573) - Exotoxin (VFC0235)] [Klebsiella pneumoniae subsp. pneumoniae 1084]
|
|
Ysa TTSS
|
ysaR
|
0.0003804 |
3 |
VF1025
|
Effector delivery system |
(ysaR) EscR/YscR/HrcR family type III secretion system export apparatus protein [Ysa TTSS (VF1025) - Effector delivery system (VFC0086)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
Intimin
|
eae
|
0.0003804 |
3 |
VF0177
|
Effector delivery system |
(eae) intimin [Intimin (VF0177) - Effector delivery system (VFC0086)] [Escherichia coli O127:H6 str. E2348/69]
|
|
LPS
|
rfbD
|
0.0001268 |
1 |
VF0056
|
Immune modulation |
(rfbD) GDP-D-mannose dehydratase [LPS (VF0056) - Immune modulation (VFC0258)] [Helicobacter pylori 26695]
|
|
Allantion utilization
|
allR
|
4.010904 |
7,875 |
VF0572
|
Nutritional/Metabolic factor |
(allA) ureidoglycolate hydrolase [Allantion utilization (VF0572) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
MtrCDE
|
mtrD
|
0.0002536 |
2 |
VF0451
|
Antimicrobial activity/Competitive advantage |
(mtrD) multiple transferable resistance system protein MtrD [MtrCDE (VF0451) - Antimicrobial activity/Competitive advantage (VFC0325)] [Neisseria meningitidis MC58]
|
|
T4SS secreted effectors
|
CBU_1566
|
0.002409 |
19 |
VF0696
|
Effector delivery system |
(CBU_1566) Coxiella Dot/Icm type IVB secretion system translocated effector [T4SS secreted effectors (VF0696) - Effector delivery system (VFC0086)] [Coxiella burnetii RSA 493]
|
|
T2SS
|
gspD
|
0.4276658 |
285 |
VF0333
|
Effector delivery system |
(gspI) general secretion pathway protein I [T2SS (VF0333) - Effector delivery system (VFC0086)] [Shigella dysenteriae Sd197]
|
|
BapA
|
bapA
|
0.0007607 |
2 |
VF0971
|
Adherence |
|
|
SiiE
|
siiE
|
0.0005072 |
3 |
VF0970
|
Adherence |
(siiE) non-fimbrial adhesin SiiE [SiiE (VF0970) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Heat-stable toxin (ST)
|
estIa
|
0.0002536 |
2 |
VF0211
|
Exotoxin |
(estIa) heat stable enterotoxin I [Heat-stable toxin (ST) (VF0211) - Exotoxin (VFC0235)] [Escherichia coli O78:H11:K80 str. H10407]
|
|
AAFs
|
aafC
|
0.0012679 |
10 |
VF0214
|
Adherence |
(aafC) aggregative adherence fimbria II usher protein AafC [AAFs (VF0214) - Adherence (VFC0001)] [Escherichia coli O44:H18 042]
|
|
VAS T6SS
|
clpB/vasG
|
0.0001268 |
1 |
VF0335
|
Effector delivery system |
(clpB/vasG) type VI secretion system AAA+ family ATPase [VAS T6SS (VF0335) - Effector delivery system (VFC0086)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
Invasin D
|
invD
|
0.0001268 |
1 |
VF0576
|
Invasion |
(invD) invasin D protein [Invasin D (VF0576) - Invasion (VFC0083)] [Yersinia pseudotuberculosis IP 31758]
|
|
Adhesive fimbriae
|
cfaD/cfaE
|
2.6973501 |
7,828 |
VF0213
|
Adherence |
(cfaD/cfaE) minor pilin and initiator [Adhesive fimbriae (VF0213) - Adherence (VFC0001)] [Escherichia coli E24377A]
|
|
T6SS
|
hcp1/tssD1
|
0.4173957 |
350 |
VF0579
|
Effector delivery system |
(tssG) Type VI secretion system protein TssG [T6SS (VF0579) - Effector delivery system (VFC0086)] [Shigella sonnei Ss046]
|
|
SCI (Salmonella centrisome island)/SPI-6 T6SS
|
STM0267
|
7.7672119 |
7,556 |
VF0974
|
Effector delivery system |
|
|
Dispersin
|
aatA
|
0.0008875 |
2 |
VF0215
|
Others |
(aatA) outer membrane protein AatA [Dispersin (VF0215) - Others (VFC0346)] [Escherichia coli O44:H18 042]
|
|
Pic
|
pic
|
0.0036769 |
29 |
VF0218
|
Effector delivery system |
(pic) Pic serine protease precursor, autotransporter [Pic (VF0218) - Effector delivery system (VFC0086)] [Escherichia coli O44:H18 042]
|
|
Eps T2SS
|
epsE
|
0.0001268 |
1 |
VF0613
|
Effector delivery system |
(epsE) type II secretion system ATPase GspE [Eps T2SS (VF0613) - Effector delivery system (VFC0086)] [Vibrio cholerae O395]
|
|
Pet
|
pet
|
0.0007607 |
6 |
VF0217
|
Effector delivery system |
(pet) Pet serine protease precursor, autotransporter [Pet (VF0217) - Effector delivery system (VFC0086)] [Escherichia coli O44:H18 042]
|
|
VirF
|
virF
|
0.8820844 |
6,934 |
VF0979
|
Regulation |
(virF) transcriptional activator VirF [VirF (VF0979) - Regulation (VFC0301)] [Shigella flexneri 2a str. 301]
|
|
TTSS secreted effectors
|
ipaJ
|
28.7703816 |
7,805 |
VF0978
|
Effector delivery system |
(ospG) type III secretion system effector OspG, protein kinase [TTSS secreted effectors (VF0978) - Effector delivery system (VFC0086)] [Shigella flexneri 2a str. 301]
|
|
CcmC
|
ccmF
|
0.0001268 |
1 |
VF0292
|
Nutritional/Metabolic factor |
(ccmF) cytochrome c heme lyase subunit CcmF [CcmC (VF0292) - Nutritional/Metabolic factor (VFC0272)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Urease
|
ureG
|
0.0003804 |
2 |
VF0050
|
Stress survival |
(ureG) urease accessory protein (ureG) [Urease (VF0050) - Stress survival (VFC0282)] [Helicobacter pylori 26695]
|
|
LPS
|
rfbC
|
0.0376569 |
297 |
VF0171
|
Immune modulation |
(rfbC) dTDP-4-dehydrorhamnose 3,5-epimerase [LPS (VF0171) - Immune modulation (VFC0258)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
EspC
|
espC
|
0.008495 |
54 |
VF0173
|
Effector delivery system |
(espC) Type III secretion system secreted protein, serine protease [EspC (VF0173) - Effector delivery system (VFC0086)] [Escherichia coli O127:H6 str. E2348/69]
|
|
TTSS
|
escD
|
0.0106504 |
5 |
VF0172
|
Effector delivery system |
(cesD2) chaperone for EspD [TTSS (VF0172) - Effector delivery system (VFC0086)] [Escherichia coli O127:H6 str. E2348/69]
|
|
Lymphostatin/LifA
|
lifA/efa1
|
0.0001268 |
1 |
VF0175
|
Effector delivery system |
(lifA/efa1) lymphostatin Efa1/LifA [Lymphostatin/LifA (VF0175) - Effector delivery system (VFC0086)] [Escherichia coli O55:H7 str. CB9615]
|
|
RcsAB
|
rcsB
|
1.996957 |
7,886 |
VF0571
|
Regulation |
(rcsA) transcriptional activator for ctr capsule biosynthesis [RcsAB (VF0571) - Regulation (VFC0301)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
FarAB
|
farB
|
0.0067199 |
53 |
VF0450
|
Antimicrobial activity/Competitive advantage |
(farA) fatty acid efflux system protein FarA [FarAB (VF0450) - Antimicrobial activity/Competitive advantage (VFC0325)] [Neisseria meningitidis MC58]
|
|
BFP
|
bfpH
|
0.0008875 |
3 |
VF0174
|
Adherence |
(bfpF) retraction ATPase [BFP (VF0174) - Adherence (VFC0001)] [Escherichia coli O127:H6 str. E2348/69]
|