|
IcsP (SopA)
|
icsP/sopA
|
0.3804321 |
3,117 |
VF0122
|
Exoenzyme |
(icsP/sopA) outer membrane protease of the OmpP family, involved in cleavage of surface exposed IcsA [IcsP (SopA) (VF0122) - Exoenzyme (VFC0251)] [Shigella flexneri 2a str. 301]
|
|
IcsA (VirG)
|
icsA/virG
|
0.412236 |
3,255 |
VF0121
|
Motility |
(icsA/virG) autotransporter, actin tail assembly protein IcsA/VirG [IcsA (VirG) (VF0121) - Motility (VFC0204)] [Shigella flexneri 2a str. 301]
|
|
LPS
|
gtr
|
0.0222141 |
100 |
VF0124
|
Immune modulation |
(gtr) glucosyl tranferase [LPS (VF0124) - Immune modulation (VFC0258)] [Shigella flexneri 2a str. 301]
|
|
Capsule
|
cap8E
|
0.0019422 |
15 |
VF0003
|
Immune modulation |
(cap8E) type 8 capsular polysaccharide synthesis protein Cap8E [Capsule (VF0003) - Immune modulation (VFC0258)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Aerobactin
|
iutA
|
4.9263171 |
8,138 |
VF0123
|
Nutritional/Metabolic factor |
(iucC) aerobactin synthesis protein IucC [Aerobactin (VF0123) - Nutritional/Metabolic factor (VFC0272)] [Shigella flexneri 2a str. 301]
|
|
Type IV pili
|
pilN
|
0.0002428 |
2 |
VF0401
|
Adherence |
(pilN) type IV pilus inner membrane platform protein PilN [Type IV pili (VF0401) - Adherence (VFC0001)] [Yersinia pseudotuberculosis IP 31758]
|
|
LPS
|
acpXL
|
0.9985433 |
8,226 |
VF0367
|
Immune modulation |
(acpXL) acyl carrier protein [LPS (VF0367) - Immune modulation (VFC0258)] [Brucella melitensis bv. 1 str. 16M]
|
|
SinH
|
sinH
|
0.0023064 |
18 |
VF0400
|
Adherence |
(sinH) intimin-like protein [SinH (VF0400) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
ACF
|
acfD
|
0.0001214 |
1 |
VF0127
|
Others |
(acfD) accessory colonization factor AcfD [ACF (VF0127) - Others (VFC0346)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
ECP
|
ykgK/ecpR
|
0.0729546 |
100 |
VF0404
|
Adherence |
(ykgK/ecpR) regulator protein EcpR [ECP (VF0404) - Adherence (VFC0001)] [Escherichia coli O157:H7 str. EDL933]
|
|
AI-2
|
luxS
|
1 |
8,237 |
VF0406
|
Biofilm |
(luxS) S-ribosylhomocysteinase [AI-2 (VF0406) - Biofilm (VFC0271)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
Type IV pili
|
vfr
|
1.0004856 |
8,238 |
VF0082
|
Adherence |
(pilB) type 4 fimbrial biogenesis protein PilB [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1]
|
|
LPS
|
PA3143
|
0.0048555 |
37 |
VF0085
|
Immune modulation |
(wbpM) nucleotide sugar epimerase/dehydratase WbpM [LPS (VF0085) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1]
|
|
T6SS
|
vipB
|
2.9342073 |
8,092 |
VF0480
|
Effector delivery system |
(vasK/icmF) Type VI secretion system protein [T6SS (VF0480) - Effector delivery system (VFC0086)] [Aeromonas hydrophila subsp. hydrophila ATCC 7966]
|
|
Pic
|
pic
|
0.2000486 |
1,636 |
VF0120
|
Exoenzyme |
(pic) serine protease, autotransporter Pic [Pic (VF0120) - Exoenzyme (VFC0251)] [Shigella flexneri 2a str. 301]
|
|
TraJ
|
AAA92657
|
0.0137169 |
111 |
VF0241
|
Invasion |
(AAA92657) unknown protein [TraJ (VF0241) - Invasion (VFC0083)] [Escherichia coli]
|
|
Capsule
|
cpsB/cdsA
|
0.0001214 |
1 |
VF0361
|
Immune modulation |
(cpsB/cdsA) phosphatidate cytidylyltransferase [Capsule (VF0361) - Immune modulation (VFC0258)] [Enterococcus faecalis V583]
|
|
Pic
|
pic
|
0.0007283 |
6 |
VF0232
|
Effector delivery system |
(pic) Pic serine protease precursor, autotransporter [Pic (VF0232) - Effector delivery system (VFC0086)] [Escherichia coli CFT073]
|
|
Lateral flagella
|
lfhA
|
0.0041272 |
32 |
VF0474
|
Motility |
(lfgG) lateral flagellar basal-body rod protein LfgG [Lateral flagella (VF0474) - Motility (VFC0204)] [Aeromonas salmonicida subsp. salmonicida A449]
|
|
PhoPQ
|
phoP
|
1.9996358 |
8,238 |
VF0111
|
Regulation |
(phoP) response regulator in two-component regulatory system with PhoQ [PhoPQ (VF0111) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
LOS
|
lgtE
|
0.0001214 |
1 |
VF0078
|
Immune modulation |
(lgtE) glycosyltransferase family 25 protein [LOS (VF0078) - Immune modulation (VFC0258)] [Neisseria meningitidis MC58]
|
|
Polar flagella
|
nueA
|
1.9992717 |
8,237 |
VF0473
|
Motility |
(nueA) NeuA protein [Polar flagella (VF0473) - Motility (VFC0204)] [Aeromonas hydrophila ML09-119]
|
|
Sat
|
sat
|
0.0492838 |
252 |
VF0231
|
Effector delivery system |
(sat) Aecreted auto transpoter toxin [Sat (VF0231) - Effector delivery system (VFC0086)] [Escherichia coli CFT073]
|
|
GroEL
|
groEL
|
0.0001214 |
1 |
VF0594
|
Adherence |
(groEL) chaperonin GroEL [GroEL (VF0594) - Adherence (VFC0001)] [Clostridium difficile 630]
|
|
Fur
|
fur
|
0.9998786 |
8,235 |
VF0113
|
Regulation |
(fur) ferric iron uptake transcriptional regulator [Fur (VF0113) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Chu
|
chuX
|
0.0142025 |
26 |
VF0234
|
Nutritional/Metabolic factor |
(chuY) ChuY [Chu (VF0234) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli O157:H7 str. EDL933]
|
|
RpoS
|
rpoS
|
1.040301 |
8,216 |
VF0112
|
Regulation |
(rpoS) RNA polymerase sigma factor RpoS [RpoS (VF0112) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Tsh
|
tsh
|
0.0004856 |
4 |
VF0233
|
Effector delivery system |
(tsh) temperature-sensitive protein Tsh [Tsh (VF0233) - Effector delivery system (VFC0086)] [Escherichia coli O25b:H4-ST131]
|
|
OmpA
|
ompA
|
0.9997572 |
8,233 |
VF0236
|
Invasion |
(ompA) outer membrane protein A [OmpA (VF0236) - Invasion (VFC0083)] [Escherichia coli O18:K1:H7 str. RS218]
|
|
Exe T2SS
|
exeG
|
0.0106822 |
63 |
VF0478
|
Effector delivery system |
(exeF) general secretion pathway protein F [Exe T2SS (VF0478) - Effector delivery system (VFC0086)] [Aeromonas hydrophila ML09-119]
|
|
S fimbriae
|
sfaH
|
0.0001214 |
1 |
VF0235
|
Adherence |
(sfaH) S fimbriae adhesin SfaH [S fimbriae (VF0235) - Adherence (VFC0001)] [Escherichia coli O18:K1:H7 str. IHE3034]
|
|
Shiga toxin
|
stxA
|
0.0197864 |
62 |
VF0117
|
Exotoxin |
(stxB) Shiga toxin subunit B precursor [Shiga toxin (VF0117) - Exotoxin (VFC0235)] [Shigella dysenteriae Sd197]
|
|
AslA
|
aslA
|
0.9887109 |
8,145 |
VF0238
|
Invasion |
(aslA) putative arylsulfatase [AslA (VF0238) - Invasion (VFC0083)] [Escherichia coli O18:K1:H7 str. RS218]
|
|
IlpA
|
IlpA
|
0.9995144 |
8,232 |
VF0513
|
Adherence |
(IlpA) immunogenic lipoprotein A [IlpA (VF0513) - Adherence (VFC0001)] [Vibrio vulnificus YJ016]
|
|
Ibes
|
ibeC
|
2.015295 |
8,238 |
VF0237
|
Invasion |
(ibeB) Cu(+)/Ag(+) efflux RND transporter outer membrane channel CusC [Ibes (VF0237) - Invasion (VFC0083)] [Escherichia coli O45:K1:H7 str. S88]
|
|
TTSS (SPI-1 encode)
|
prgI
|
0.0332605 |
86 |
VF0116
|
Effector delivery system |
(spaP) type III secretion system minor export apparatus protein SpaP [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
SigA
|
sigA
|
0.985312 |
8,057 |
VF0119
|
Exoenzyme |
(sigA) serine protease, autotransporter SigA [SigA (VF0119) - Exoenzyme (VFC0251)] [Shigella flexneri 2a str. 301]
|
|
K1 capsule
|
kpsD
|
0.0260986 |
30 |
VF0239
|
Invasion |
(kpsD) Polysialic acid transport protein precursor [K1 capsule (VF0239) - Invasion (VFC0083)] [Escherichia coli O45:K1:H7 str. S88]
|
|
TTSS
|
spa15
|
10.8574897 |
3,246 |
VF0118
|
Effector delivery system |
(ipgE) type III secretion system chaperone for IpgD [TTSS (VF0118) - Effector delivery system (VFC0086)] [Shigella flexneri 2a str. 301]
|
|
Yst1 T2SS
|
yst1G
|
0.0001214 |
1 |
VF0635
|
Effector delivery system |
(yst1G) type II secretion system major pseudopilin GspG [Yst1 T2SS (VF0635) - Effector delivery system (VFC0086)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
Flagella
|
flrA
|
0.0001214 |
1 |
VF0519
|
Motility |
(flrA) sigma-54 dependent transcriptional activator [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
TTSS
|
escD
|
0.0661568 |
24 |
VF0191
|
Effector delivery system |
(cesF) CesF, chaperone for EspF [TTSS (VF0191) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933]
|
|
ClpC
|
clpC
|
0.0003642 |
3 |
VF0072
|
Stress survival |
(clpC) endopeptidase Clp ATP-binding chain C [ClpC (VF0072) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
|
|
Ler
|
ler
|
0.0015781 |
13 |
VF0192
|
Regulation |
(ler) transcription regulator Ler [Ler (VF0192) - Regulation (VFC0301)] [Escherichia coli O157:H7 str. EDL933]
|
|
ClpP
|
clpP
|
0.9997572 |
8,236 |
VF0074
|
Stress survival |
(clpP) ATP-dependent Clp protease proteolytic subunit [ClpP (VF0074) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
|
|
Paa
|
paa
|
0.0027919 |
23 |
VF0194
|
Adherence |
(paa) outer membrane adhesin Paa [Paa (VF0194) - Adherence (VFC0001)] [Escherichia coli O157:H7 str. EDL933]
|
|
PNAG
|
pgaC
|
0.0001214 |
1 |
VF0472
|
Biofilm |
(pgaC) poly-beta-1,6 N-acetyl-D-glucosamine synthase [PNAG (VF0472) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU]
|
|
Salmochelin siderophore
|
iroN
|
0.0128672 |
39 |
VF0230
|
Nutritional/Metabolic factor |
(iroB) glucosyltransferase IroB [Salmochelin siderophore (VF0230) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073]
|
|
CD0873
|
CD0873
|
0.0001214 |
1 |
VF0593
|
Adherence |
(CD0873) ABC transporter substrate-binding protein [CD0873 (VF0593) - Adherence (VFC0001)] [Clostridium difficile 630]
|
|
Type IV pili
|
pilK
|
0.0001214 |
1 |
VF0075
|
Adherence |
(pilK) pilin-like protein may involving in pseudopilus formation [Type IV pili (VF0075) - Adherence (VFC0001)] [Neisseria meningitidis MC58]
|
|
PmrAB
|
pmrA
|
1.9942947 |
8,215 |
VF1355
|
Regulation |
(pmrB) sensory kinase PmrB [PmrAB (VF1355) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
LPS
|
wbtL
|
1.0213644 |
8,237 |
VF0542
|
Immune modulation |
(lpxA/glmU) UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase [LPS (VF0542) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
TTSS secreted effectors
|
espM1
|
1.9819131 |
8,194 |
VF1111
|
Effector delivery system |
(nleG2-2) DUF1076 domain-containing protein [TTSS secreted effectors (VF1111) - Effector delivery system (VFC0086)] [Escherichia coli O55:H7 str. CB9615]
|
|
Vat
|
vat
|
0.002185 |
7 |
VF1112
|
Effector delivery system |
(vat) vacuolating autotransporter toxin [Vat (VF1112) - Effector delivery system (VFC0086)] [Escherichia coli CFT073]
|
|
Nitrate reductase
|
narH
|
0.0122603 |
99 |
VF0302
|
Nutritional/Metabolic factor |
(narH) nitrate reductase subunit beta [Nitrate reductase (VF0302) - Nutritional/Metabolic factor (VFC0272)] [Mycobacterium tuberculosis H37Rv]
|
|
Capsule
|
rpe
|
0.9998786 |
8,236 |
VF0543
|
Immune modulation |
(rpe) ribulose-phosphate 3-epimerase [Capsule (VF0543) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
TTSS effectors secreted via both systems
|
spvD
|
0.0002428 |
1 |
VF0948
|
Effector delivery system |
(spvC) type III secretion system effector SpvC, phosphothreonine lyase [TTSS effectors secreted via both systems (VF0948) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
CsrA
|
csrA
|
1 |
8,237 |
VF0261
|
Regulation |
(csrA) carbon storage regulator CsrA [CsrA (VF0261) - Regulation (VFC0301)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
TTSS secreted effectors
|
nleF
|
9.6495509 |
8,237 |
VF1110
|
Effector delivery system |
(nleE) Type III secretion system effector NleE [TTSS secreted effectors (VF1110) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933]
|
|
SCI T6SS secreted effectors
|
tae4
|
0.0195436 |
61 |
VF1195
|
Effector delivery system |
(tae4) type VI secretion system effector tae4, L,D-endopeptidase [SCI T6SS secreted effectors (VF1195) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
LetA/S
|
letA
|
0.0004856 |
4 |
VF0262
|
Regulation |
(letA) UvrY/SirA/GacA family response regulator transcription factor [LetA/S (VF0262) - Regulation (VFC0301)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Isocitrate lyase
|
icl
|
1.0014567 |
8,234 |
VF0253
|
Others |
(icl) Isocitrate lyase Icl (isocitrase) (isocitratase) [Isocitrate lyase (VF0253) - Others (VFC0346)] [Mycobacterium tuberculosis H37Rv]
|
|
Shu
|
shuV
|
0.0010925 |
8 |
VF0256
|
Nutritional/Metabolic factor |
(shuA) outer membrane heme/hemoglobin receptor ShuA [Shu (VF0256) - Nutritional/Metabolic factor (VFC0272)] [Shigella dysenteriae Sd197]
|
|
ShET2
|
senB
|
0.9657684 |
7,948 |
VF0258
|
Exotoxin |
(senB) enterotoxin [ShET2 (VF0258) - Exotoxin (VFC0235)] [Shigella boydii Sb227]
|
|
Yersiniabactin
|
ybtS
|
0.0478271 |
45 |
VF0136
|
Nutritional/Metabolic factor |
(irp1) yersiniabactin biosynthetic protein Irp1 [Yersiniabactin (VF0136) - Nutritional/Metabolic factor (VFC0272)] [Yersinia pestis CO92]
|
|
SigA
|
sigA/rpoV
|
0.0001214 |
1 |
VF0257
|
Regulation |
(sigA/rpoV) RNA polymerase sigma factor SigA [SigA (VF0257) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
F1 antigen
|
caf1A
|
0.0001214 |
1 |
VF0138
|
Immune modulation |
(caf1A) F1 capsule anchoring protein [F1 antigen (VF0138) - Immune modulation (VFC0258)] [Yersinia pestis CO92]
|
|
TcpC
|
tcpC
|
0.0001214 |
1 |
VF0413
|
Immune modulation |
(tcpC) Tir domain containing protein TcpC [TcpC (VF0413) - Immune modulation (VFC0258)] [Escherichia coli CFT073]
|
|
Alkaline protease
|
aprA
|
0.0001214 |
1 |
VF0090
|
Exoenzyme |
(aprA) alkaline metalloproteinase precursor [Alkaline protease (VF0090) - Exoenzyme (VFC0251)] [Pseudomonas aeruginosa PAO1]
|
|
Alginate
|
algU
|
1.0001214 |
8,236 |
VF0091
|
Biofilm |
(algU) alginate biosynthesis protein AlgZ/FimS [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1]
|
|
Pyoverdine
|
pvcA
|
0.0001214 |
1 |
VF0094
|
Nutritional/Metabolic factor |
(pvcA) paerucumarin biosynthesis protein PvcA [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1]
|
|
Quorum sensing
|
rhlR
|
0.0013353 |
11 |
VF0093
|
Biofilm |
(rhlR) transcriptional regulator RhlR [Quorum sensing (VF0093) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1]
|
|
FnBPs
|
fnbA
|
0.0001214 |
1 |
VF0010
|
Adherence |
(fnbA) fibronectin-binding protein A [FnBPs (VF0010) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Ent
|
entF
|
0.0004856 |
1 |
VF0562
|
Nutritional/Metabolic factor |
(entB) 2,3-dihydro-2,3-dihydroxybenzoate synthetase, isochroismatase [Ent (VF0562) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
LPS
|
KP1_RS17225
|
0.0033989 |
5 |
VF0561
|
Immune modulation |
(KP1_RS17230) glycosyltransferase [LPS (VF0561) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
LOS
|
rffG
|
12.0184511 |
8,238 |
VF0044
|
Immune modulation |
(msbA) lipid transporter ATP-binding/permease [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20]
|
|
LigA
|
ligA
|
0.0001214 |
1 |
VF0165
|
Effector delivery system |
(ligA) LigA, interaptin [LigA (VF0165) - Effector delivery system (VFC0086)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
KatAB
|
katA
|
0.0026706 |
22 |
VF0168
|
Stress survival |
(katA) catalase/(hydro)peroxidase [KatAB (VF0168) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Ybt
|
ybtS
|
0.0111678 |
44 |
VF0564
|
Nutritional/Metabolic factor |
(fyuA) yersiniabactin receptor FyuA [Ybt (VF0564) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
ToxB
|
toxB
|
0.0032775 |
19 |
VF0203
|
Effector delivery system |
(toxB) cytotoxin [ToxB (VF0203) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933]
|
|
Type I fimbriae
|
fimH
|
0.0140811 |
105 |
VF0566
|
Adherence |
(fimH) type 1 fimbrial adhesin precursor [Type I fimbriae (VF0566) - Adherence (VFC0001)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Capsule
|
glf
|
0.0006069 |
5 |
VF0323
|
Immune modulation |
(kpsF) D-arabinose 5-phosphate isomerase [Capsule (VF0323) - Immune modulation (VFC0258)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
|
|
SodB
|
sodB
|
1 |
8,235 |
VF0169
|
Stress survival |
(sodB) superoxide dismutase [SodB (VF0169) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Aerobactin
|
iutA
|
0.0032775 |
27 |
VF0565
|
Nutritional/Metabolic factor |
(iutA) ferric aerobactin receptor IutA [Aerobactin (VF0565) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Intimin
|
eae
|
0.0013353 |
11 |
VF0202
|
Effector delivery system |
(eae) intimin type gamma [Intimin (VF0202) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933]
|
|
AcrAB
|
acrA
|
7.8935421 |
8,238 |
VF0568
|
Antimicrobial activity/Competitive advantage |
(acrB) acriflavine resistance protein B [AcrAB (VF0568) - Antimicrobial activity/Competitive advantage (VFC0325)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Type 3 fimbriae
|
mrkF
|
0.0036417 |
6 |
VF0567
|
Biofilm |
(mrkC) fimbrial biogenesis outer membrane usher protein mrkC precursor [Type 3 fimbriae (VF0567) - Biofilm (VFC0271)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Curli fibers
|
csgC
|
7.2220199 |
8,225 |
VF1138
|
Adherence |
(csgB) curlin minor subunit CsgB [Curli fibers (VF1138) - Adherence (VFC0001)] [Escherichia coli O25b:H4-ST131]
|
|
Efa-1/LifA
|
lifA/efa1
|
0.0020636 |
12 |
VF0204
|
Effector delivery system |
(lifA/efa1) lymphostatin Efa1/LifA [Efa-1/LifA (VF0204) - Effector delivery system (VFC0086)] [Escherichia coli O103:H2 str. 12009]
|
|
T4P
|
pilS
|
0.0108036 |
87 |
VF0966
|
Invasion |
(pilQ) Flp pilus assembly complex ATPase component TadA [T4P (VF0966) - Invasion (VFC0083)] [Salmonella enterica subsp. enterica serovar Typhi str. CT18]
|
|
Hemolysin
|
hlyA
|
0.01311 |
27 |
VF0207
|
Exotoxin |
(hlyC) Hemolysin C [Hemolysin (VF0207) - Exotoxin (VFC0235)] [Escherichia coli O157:H7 str. EDL933]
|
|
T6SS
|
vipA/tssB
|
0.0120175 |
17 |
VF0569
|
Effector delivery system |
(vipB/tssC) type VI secretion system contractile sheath large subunit VipB [T6SS (VF0569) - Effector delivery system (VFC0086)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Stx
|
stx2B
|
0.0133528 |
19 |
VF0206
|
Exotoxin |
(stx2B) shiga-like toxin II B subunit encoded by bacteriophage BP-933W [Stx (VF0206) - Exotoxin (VFC0235)] [Escherichia coli O157:H7 str. EDL933]
|
|
StcE
|
stcE
|
0.0019422 |
14 |
VF0209
|
Exoenzyme |
(stcE) metalloprotease [StcE (VF0209) - Exoenzyme (VFC0251)] [Escherichia coli O157:H7 str. EDL933]
|
|
EspP
|
espP
|
0.0032775 |
24 |
VF0208
|
Effector delivery system |
(espP) autotransporter, serine protease [EspP (VF0208) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933]
|
|
Capsule
|
rfbK1
|
9.056203 |
8,238 |
VF0560
|
Immune modulation |
(KP1_RS17305) GDP-L-fucose synthase [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Capsule
|
bexD'
|
0.0002428 |
1 |
VF0043
|
Immune modulation |
(bexD') BexD' [Capsule (VF0043) - Immune modulation (VFC0258)] [Haemophilus influenzae str. 1007]
|
|
MisL
|
misL
|
1.6780772 |
7,098 |
VF0397
|
Adherence |
(misL) putative autotransporter [MisL (VF0397) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
LPS
|
bplL
|
0.0044914 |
37 |
VF0033
|
Immune modulation |
(bplL) lipopolysaccharide biosynthesis protein [LPS (VF0033) - Immune modulation (VFC0258)] [Bordetella pertussis Tohama I]
|
|
Flagella
|
fleQ
|
0.0002428 |
1 |
VF0157
|
Motility |
(fleQ) transcriptional regulator FleQ [Flagella (VF0157) - Motility (VFC0204)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
GGT
|
ggt
|
0.0001214 |
1 |
VF0553
|
Nutritional/Metabolic factor |
(ggt) gamma-glutamyltranspeptidase [GGT (VF0553) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
MgtC
|
mgtC
|
0.0001214 |
1 |
VF1365
|
Nutritional/Metabolic factor |
(mgtC) Salmonella virulence protein MgtC [MgtC (VF1365) - Nutritional/Metabolic factor (VFC0272)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Hsp60
|
htpB
|
1.0219714 |
8,237 |
VF0159
|
Adherence |
(htpB) Hsp60, 60K heat shock protein HtpB [Hsp60 (VF0159) - Adherence (VFC0001)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Capsule I
|
manC
|
0.0015781 |
12 |
VF0436
|
Immune modulation |
(manC) GDP-mannose pyrophosphorylase [Capsule I (VF0436) - Immune modulation (VFC0258)] [Burkholderia pseudomallei K96243]
|
|
EtpA
|
etpB
|
0.0001214 |
1 |
VF0437
|
Adherence |
(etpB) two-partner secretion transporter EtpB [EtpA (VF0437) - Adherence (VFC0001)] [Escherichia coli O78:H11:K80 str. H10407]
|
|
Pyrimidine biosynthesis
|
carB
|
0.0041272 |
34 |
VF0558
|
Nutritional/Metabolic factor |
(carB) carbamoyl phosphate synthase large subunit [Pyrimidine biosynthesis (VF0558) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
FbpABC
|
fbpA
|
0.0001214 |
1 |
VF0272
|
Nutritional/Metabolic factor |
(fbpA) iron(III) ABC transporter, periplasmic binding protein [FbpABC (VF0272) - Nutritional/Metabolic factor (VFC0272)] [Neisseria meningitidis MC58]
|
|
CNFy
|
cnf
|
0.0001214 |
1 |
VF0393
|
Exotoxin |
(cnf) cytotoxic necrotizing factor [CNFy (VF0393) - Exotoxin (VFC0235)] [Yersinia pseudotuberculosis YPIII]
|
|
O-antigen
|
galE
|
0.008133 |
56 |
VF0392
|
Immune modulation |
(YE_RS15420) mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase [O-antigen (VF0392) - Immune modulation (VFC0258)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
Flagella
|
motB
|
35.8509347 |
8,238 |
VF0394
|
Motility |
(fliL) flagellar basal body protein FliL [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
Type 1 fimbriae
|
fimI
|
0.5121389 |
526 |
VF0221
|
Adherence |
(fimF) FimF protein precursor [Type 1 fimbriae (VF0221) - Adherence (VFC0001)] [Escherichia coli CFT073]
|
|
Pyocyanin
|
phzG1
|
0.0001214 |
1 |
VF0100
|
Nutritional/Metabolic factor |
(phzG1) phenazine biosynthesis protein PhzG, pyridoxamine 5'-phosphate oxidase [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1]
|
|
P fimbriae
|
papC
|
0.019058 |
27 |
VF0220
|
Adherence |
(papA) P pilus major subunit PapA [P fimbriae (VF0220) - Adherence (VFC0001)] [Escherichia coli CFT073]
|
|
Type 1 fimbriae
|
fimH
|
3.9141782 |
8,135 |
VF0102
|
Adherence |
(fimZ) DNA-binding response regulator [Type 1 fimbriae (VF0102) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Capsule
|
pseI
|
0.3746055 |
3,042 |
VF0465
|
Immune modulation |
(pseC) UDP-4-amino-4, 6-dideoxy-N-acetyl-beta-L-altrosamine transaminase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU]
|
|
Dr adhesins
|
draB
|
0.0064336 |
35 |
VF0223
|
Adherence |
(draP) DraP [Dr adhesins (VF0223) - Adherence (VFC0001)] [Escherichia coli O75:K5:H- str. IH11128]
|
|
Ler
|
AAC38364
|
0.0013353 |
11 |
VF0189
|
Regulation |
(AAC38364) Orf1 [Ler (VF0189) - Regulation (VFC0301)] [Escherichia coli O127:H6 str. E2348/69]
|
|
Vi antigen
|
tviC
|
0.3662297 |
3,005 |
VF0101
|
Immune modulation |
(tviB) Vi polysaccharide biosynthesis protein, UDP-N-acetylglucosamine (UPD-GlcNAc) 6-dehydrogenase TviB [Vi antigen (VF0101) - Immune modulation (VFC0258)] [Salmonella enterica subsp. enterica serovar Typhi str. CT18]
|
|
S fimbriae
|
sfaS
|
0.0012139 |
2 |
VF0222
|
Adherence |
(sfaG) S fimbriae minor subunit SfaG [S fimbriae (VF0222) - Adherence (VFC0001)] [Escherichia coli UTI89]
|
|
Pef
|
pefC
|
0.0016994 |
11 |
VF0104
|
Adherence |
(pefD) plasmid-encoded fimbriae chaperone protein PefD [Pef (VF0104) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Alpha-Hemolysin
|
hlyA
|
0.0052197 |
10 |
VF0225
|
Exotoxin |
(hlyC) Hemolysin C [Alpha-Hemolysin (VF0225) - Exotoxin (VFC0235)] [Escherichia coli CFT073]
|
|
Agf
|
csgC
|
0.0042486 |
35 |
VF0103
|
Adherence |
(csgC) curli assembly protein CsgC [Agf (VF0103) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
F1C fimbriae
|
C_RS05810
|
0.0127458 |
89 |
VF0224
|
Adherence |
(focD) F1C fimbrial usher [F1C fimbriae (VF0224) - Adherence (VFC0001)] [Escherichia coli CFT073]
|
|
LPS
|
lpxL
|
0.0001214 |
1 |
VF0466
|
Immune modulation |
(lpxL) lauroyl acyltransferase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU]
|
|
Chu
|
chuX
|
0.0165089 |
35 |
VF0227
|
Nutritional/Metabolic factor |
(chuT) periplasmic heme-binding protein ChuT [Chu (VF0227) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073]
|
|
MgtB
|
mgtB
|
0.0006069 |
4 |
VF0106
|
Nutritional/Metabolic factor |
(mgtB) Mg2+ transport protein [MgtB (VF0106) - Nutritional/Metabolic factor (VFC0272)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
CNF-1
|
cnf1
|
0.0002428 |
2 |
VF0226
|
Exotoxin |
(cnf1) cytotoxic necrotizing factor 1 [CNF-1 (VF0226) - Exotoxin (VFC0235)] [Escherichia coli UTI89]
|
|
YplA
|
yplA
|
0.0001214 |
1 |
VF0622
|
Exotoxin |
(yplA) DUF2974 domain-containing protein [YplA (VF0622) - Exotoxin (VFC0235)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
Lpf
|
lpfD
|
0.0150522 |
52 |
VF0105
|
Adherence |
(lpfC) long polar fimbrial usher protein LpfC [Lpf (VF0105) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Aerobactin
|
iutA
|
0.0235494 |
73 |
VF0229
|
Nutritional/Metabolic factor |
(iutA) ferric aerobactin receptor precusor IutA [Aerobactin (VF0229) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073]
|
|
Rck
|
rck
|
0.0023064 |
18 |
VF0108
|
Invasion |
(rck) resistance to complement killing [Rck (VF0108) - Invasion (VFC0083)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
AdeFGH efflux pump
|
adeG
|
0.0001214 |
1 |
VF0504
|
Biofilm |
(adeG) cation/multidrug efflux pump [AdeFGH efflux pump (VF0504) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU]
|
|
Enterobactin
|
entS
|
13.9559359 |
8,238 |
VF0228
|
Nutritional/Metabolic factor |
(entE) 2,3-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073]
|
|
FdeC
|
fdeC
|
0.016873 |
114 |
VF0506
|
Adherence |
(fdeC) adhesin FdeC [FdeC (VF0506) - Adherence (VFC0001)] [Escherichia coli O45:K1:H7 str. S88]
|
|
SodCI
|
sodCI
|
0.0012139 |
10 |
VF0109
|
Stress survival |
(sodCI) Gifsy-2 prophage: superoxide dismutase precursor (Cu-Zn) [SodCI (VF0109) - Stress survival (VFC0282)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
CDT
|
cdtA
|
0.0008497 |
3 |
VF0185
|
Exotoxin |
(cdtA) cytolethal distending toxin A [CDT (VF0185) - Exotoxin (VFC0235)] [Escherichia coli O157:H str. 493/89]
|
|
EF-Tu
|
tufA
|
3.7249332 |
8,238 |
VF0460
|
Adherence |
(tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
Ysa TTSS
|
ysaR
|
0.0002428 |
2 |
VF1025
|
Effector delivery system |
(ysaR) EscR/YscR/HrcR family type III secretion system export apparatus protein [Ysa TTSS (VF1025) - Effector delivery system (VFC0086)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
Colibactin
|
clbG
|
0.0058267 |
20 |
VF0573
|
Exotoxin |
(clbC) colibactin polyketide synthase ClbC [Colibactin (VF0573) - Exotoxin (VFC0235)] [Klebsiella pneumoniae subsp. pneumoniae 1084]
|
|
Intimin
|
eae
|
0.0015781 |
13 |
VF0177
|
Effector delivery system |
(eae) intimin [Intimin (VF0177) - Effector delivery system (VFC0086)] [Escherichia coli O127:H6 str. E2348/69]
|
|
Allantion utilization
|
allB
|
3.0517116 |
8,237 |
VF0572
|
Nutritional/Metabolic factor |
(allB) allantoinase [Allantion utilization (VF0572) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
T4SS secreted effectors
|
CBU_1566
|
0.0006069 |
4 |
VF0696
|
Effector delivery system |
(CBU_1566) Coxiella Dot/Icm type IVB secretion system translocated effector [T4SS secreted effectors (VF0696) - Effector delivery system (VFC0086)] [Coxiella burnetii RSA 493]
|
|
KatA
|
katA
|
0.0002428 |
2 |
VF0454
|
Stress survival |
(katA) catalase [KatA (VF0454) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
|
|
Afa/Dr family
|
draE2
|
0.0002428 |
2 |
VF0212
|
Adherence |
(draE2) Dr-II structural adhesin precursor [Afa/Dr family (VF0212) - Adherence (VFC0001)] [Escherichia coli EC7372]
|
|
T2SS
|
gspD
|
0.0941976 |
86 |
VF0333
|
Effector delivery system |
(gspI) general secretion pathway protein I [T2SS (VF0333) - Effector delivery system (VFC0086)] [Shigella dysenteriae Sd197]
|
|
Mycobactin
|
mbtH
|
0.0001214 |
1 |
VF0299
|
Nutritional/Metabolic factor |
(mbtH) putative protein MbtH [Mycobactin (VF0299) - Nutritional/Metabolic factor (VFC0272)] [Mycobacterium tuberculosis H37Rv]
|
|
Heat-stable toxin (ST)
|
estIa
|
0.0001214 |
1 |
VF0211
|
Exotoxin |
(estIa) heat stable enterotoxin I [Heat-stable toxin (ST) (VF0211) - Exotoxin (VFC0235)] [Escherichia coli O78:H11:K80 str. H10407]
|
|
VAS T6SS
|
vipB/mglB
|
0.0007283 |
6 |
VF0335
|
Effector delivery system |
(vasH) type VI secretion system regulatory protein VasH [VAS T6SS (VF0335) - Effector delivery system (VFC0086)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
AAFs
|
aafC
|
0.0038844 |
28 |
VF0214
|
Adherence |
(aafC) aggregative adherence fimbria II usher protein AafC [AAFs (VF0214) - Adherence (VFC0001)] [Escherichia coli O44:H18 042]
|
|
MsrAB
|
msrA/B(pilB
|
0.0001214 |
1 |
VF0456
|
Stress survival |
(msrA/B(pilB)) trifunctional thioredoxin/methionine sulfoxide reductase A/B protein [MsrAB (VF0456) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
|
|
HSI-1
|
clpV1
|
0.0002428 |
1 |
VF0334
|
Effector delivery system |
(clpV1) type VI secretion system AAA+ family ATPase [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
Adhesive fimbriae
|
cfaD/cfaE
|
5.440034 |
8,183 |
VF0213
|
Adherence |
(cfaD/cfaE) minor pilin and initiator [Adhesive fimbriae (VF0213) - Adherence (VFC0001)] [Escherichia coli E24377A]
|
|
Invasin D
|
invD
|
0.0002428 |
2 |
VF0576
|
Invasion |
(invD) invasin D protein [Invasin D (VF0576) - Invasion (VFC0083)] [Yersinia pseudotuberculosis IP 31758]
|
|
T6SS
|
hcp1/tssD1
|
27.081816 |
8,141 |
VF0579
|
Effector delivery system |
(tssG) Type VI secretion system protein TssG [T6SS (VF0579) - Effector delivery system (VFC0086)] [Shigella sonnei Ss046]
|
|
Dispersin
|
aatA
|
0.0019422 |
5 |
VF0215
|
Others |
(aatA) outer membrane protein AatA [Dispersin (VF0215) - Others (VFC0346)] [Escherichia coli O44:H18 042]
|
|
RecN
|
recN
|
0.0001214 |
1 |
VF0457
|
Stress survival |
(recN) DNA repair protein RecN [RecN (VF0457) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
|
|
SCI (Salmonella centrisome island)/SPI-6 T6SS
|
tssJ
|
0.0941976 |
102 |
VF0974
|
Effector delivery system |
|
|
Pic
|
pic
|
0.7585579 |
6,248 |
VF0218
|
Effector delivery system |
(pic) Pic serine protease precursor, autotransporter [Pic (VF0218) - Effector delivery system (VFC0086)] [Escherichia coli O44:H18 042]
|
|
Pet
|
pet
|
0.0003642 |
2 |
VF0217
|
Effector delivery system |
(pet) Pet serine protease precursor, autotransporter [Pet (VF0217) - Effector delivery system (VFC0086)] [Escherichia coli O44:H18 042]
|
|
Eps T2SS
|
epsE
|
0.0002428 |
2 |
VF0613
|
Effector delivery system |
(epsE) type II secretion system ATPase GspE [Eps T2SS (VF0613) - Effector delivery system (VFC0086)] [Vibrio cholerae O395]
|
|
VirF
|
virF
|
0.3180384 |
2,604 |
VF0979
|
Regulation |
(virF) transcriptional activator VirF [VirF (VF0979) - Regulation (VFC0301)] [Shigella flexneri 2a str. 301]
|
|
TTSS secreted effectors
|
ipaJ
|
13.7902403 |
8,121 |
VF0978
|
Effector delivery system |
(ospG) type III secretion system effector OspG, protein kinase [TTSS secreted effectors (VF0978) - Effector delivery system (VFC0086)] [Shigella flexneri 2a str. 301]
|
|
CcmC
|
ccmF
|
0.0003642 |
3 |
VF0292
|
Nutritional/Metabolic factor |
(ccmF) cytochrome c heme lyase subunit CcmF [CcmC (VF0292) - Nutritional/Metabolic factor (VFC0272)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
LPS
|
rfbC
|
0.0016994 |
14 |
VF0171
|
Immune modulation |
(rfbC) dTDP-4-dehydrorhamnose 3,5-epimerase [LPS (VF0171) - Immune modulation (VFC0258)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Urease
|
ureG
|
0.0048555 |
19 |
VF0050
|
Stress survival |
(ureG) urease accessory protein (ureG) [Urease (VF0050) - Stress survival (VFC0282)] [Helicobacter pylori 26695]
|
|
EspC
|
espC
|
0.0006069 |
4 |
VF0173
|
Effector delivery system |
(espC) Type III secretion system secreted protein, serine protease [EspC (VF0173) - Effector delivery system (VFC0086)] [Escherichia coli O127:H6 str. E2348/69]
|
|
TTSS
|
escD
|
0.0268269 |
15 |
VF0172
|
Effector delivery system |
(cesD2) chaperone for EspD [TTSS (VF0172) - Effector delivery system (VFC0086)] [Escherichia coli O127:H6 str. E2348/69]
|
|
Flagella
|
tlpA
|
0.0001214 |
1 |
VF0051
|
Motility |
(tlpA) membrane-bound chemoreceptor sensing arginine and bicarbonate [Flagella (VF0051) - Motility (VFC0204)] [Helicobacter pylori 26695]
|
|
RcsAB
|
rcsB
|
2.002185 |
8,238 |
VF0571
|
Regulation |
(rcsA) transcriptional activator for ctr capsule biosynthesis [RcsAB (VF0571) - Regulation (VFC0301)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Lymphostatin/LifA
|
lifA/efa1
|
0.0033989 |
20 |
VF0175
|
Effector delivery system |
(lifA/efa1) lymphostatin Efa1/LifA [Lymphostatin/LifA (VF0175) - Effector delivery system (VFC0086)] [Escherichia coli O55:H7 str. CB9615]
|
|
FarAB
|
farB
|
0.0013353 |
9 |
VF0450
|
Antimicrobial activity/Competitive advantage |
(farA) fatty acid efflux system protein FarA [FarAB (VF0450) - Antimicrobial activity/Competitive advantage (VFC0325)] [Neisseria meningitidis MC58]
|
|
BFP
|
bfpU
|
0.0041272 |
7 |
VF0174
|
Adherence |
(bfpP) prepilin peptidase BfpP [BFP (VF0174) - Adherence (VFC0001)] [Escherichia coli O127:H6 str. E2348/69]
|