| dfrC |
ARO:3002865 |
1 |
diaminopyrimidine antibiotic |
antibiotic target replacement |
trimethoprim resistant dihydrofolate reductase dfr |
| vanH gene in vanD cluster |
ARO:3002944 |
1 |
glycopeptide antibiotic |
antibiotic target alteration |
vanH; glycopeptide resistance gene cluster |
| lsaC |
ARO:3003112 |
15 |
lincosamide antibiotic; streptogramin antibiotic; pleuromutilin antibiotic |
antibiotic target protection |
lsa-type ABC-F protein |
| Streptococcus pneumoniae parC conferring resistance to fluoroquinolones |
ARO:3003311 |
201 |
fluoroquinolone antibiotic |
antibiotic target alteration |
fluoroquinolone resistant parC |
| nimJ |
ARO:3007112 |
1 |
nitroimidazole antibiotic |
antibiotic inactivation |
nitroimidazole reductase |
| tet(45) |
ARO:3003196 |
6 |
tetracycline antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) |
ARO:3005099 |
5 |
macrolide antibiotic; lincosamide antibiotic; streptogramin antibiotic |
antibiotic target alteration |
Erm 23S ribosomal RNA methyltransferase |
| mphL |
ARO:3003072 |
1 |
macrolide antibiotic |
antibiotic inactivation |
macrolide phosphotransferase (MPH) |
| clbA |
ARO:3002814 |
1 |
lincosamide antibiotic; streptogramin antibiotic; streptogramin A antibiotic; oxazolidinone antibiotic; phenicol antibiotic; pleuromutilin antibiotic |
antibiotic target alteration |
Cfr 23S ribosomal RNA methyltransferase |
| lmrB |
ARO:3002813 |
1 |
lincosamide antibiotic |
antibiotic efflux |
ATP-binding cassette (ABC) antibiotic efflux pump |
| vanT gene in vanG cluster |
ARO:3002972 |
299 |
glycopeptide antibiotic |
antibiotic target alteration |
glycopeptide resistance gene cluster; vanT |
| SAT-4 |
ARO:3002897 |
132 |
nucleoside antibiotic |
antibiotic inactivation |
streptothricin acetyltransferase (SAT) |
| tet(W) |
ARO:3000194 |
1 |
tetracycline antibiotic |
antibiotic target protection |
tetracycline-resistant ribosomal protection protein |
| tetA(60) |
ARO:3004035 |
1 |
tetracycline antibiotic |
antibiotic efflux |
ATP-binding cassette (ABC) antibiotic efflux pump |
| Streptomyces rimosus otr(A) |
ARO:3002891 |
3 |
tetracycline antibiotic |
antibiotic target protection |
tetracycline-resistant ribosomal protection protein |
| tet(S) |
ARO:3000192 |
10 |
tetracycline antibiotic |
antibiotic target protection |
tetracycline-resistant ribosomal protection protein |
| vanXY gene in vanG cluster |
ARO:3003069 |
2 |
glycopeptide antibiotic |
antibiotic target alteration |
glycopeptide resistance gene cluster; vanXY |
| vmlR |
ARO:3004476 |
1 |
lincosamide antibiotic; streptogramin antibiotic; streptogramin B antibiotic |
antibiotic target protection |
Miscellaneous ABC-F subfamily ATP-binding cassette ribosomal protection proteins |
| tetB(60) |
ARO:3004036 |
1 |
tetracycline antibiotic |
antibiotic efflux |
ATP-binding cassette (ABC) antibiotic efflux pump |
| BcIII |
ARO:3007101 |
3 |
cephalosporin; penem |
antibiotic inactivation |
class A Bacillus cereus Bc beta-lactamase |
| ykkC |
ARO:3003063 |
1 |
aminoglycoside antibiotic; tetracycline antibiotic; phenicol antibiotic |
antibiotic efflux |
small multidrug resistance (SMR) antibiotic efflux pump |
| ANT(2'')-Ia |
ARO:3000230 |
1 |
aminoglycoside antibiotic |
antibiotic inactivation |
ANT(2'') |
| tet(32) |
ARO:3000196 |
84 |
tetracycline antibiotic |
antibiotic target protection |
tetracycline-resistant ribosomal protection protein |
| ykkD |
ARO:3003064 |
1 |
aminoglycoside antibiotic; tetracycline antibiotic; phenicol antibiotic |
antibiotic efflux |
small multidrug resistance (SMR) antibiotic efflux pump |
| tetB(P) |
ARO:3000195 |
17 |
tetracycline antibiotic |
antibiotic target protection |
tetracycline-resistant ribosomal protection protein |
| tet(O) |
ARO:3000190 |
12 |
tetracycline antibiotic |
antibiotic target protection |
tetracycline-resistant ribosomal protection protein |
| vanW gene in vanB cluster |
ARO:3002964 |
2 |
glycopeptide antibiotic |
antibiotic target alteration |
vanW; glycopeptide resistance gene cluster |
| patB |
ARO:3000025 |
36,414 |
fluoroquinolone antibiotic |
antibiotic efflux |
ATP-binding cassette (ABC) antibiotic efflux pump |
| vanW gene in vanG cluster |
ARO:3002965 |
32 |
glycopeptide antibiotic |
antibiotic target alteration |
vanW; glycopeptide resistance gene cluster |
| TEM-171 |
ARO:3001037 |
1 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| patA |
ARO:3000024 |
36,421 |
fluoroquinolone antibiotic |
antibiotic efflux |
ATP-binding cassette (ABC) antibiotic efflux pump |
| APH(3')-IIIa |
ARO:3002647 |
190 |
aminoglycoside antibiotic |
antibiotic inactivation |
APH(3') |
| APH(3')-Ia |
ARO:3002641 |
3 |
aminoglycoside antibiotic |
antibiotic inactivation |
APH(3') |
| pmrA |
ARO:3000822 |
34,749 |
fluoroquinolone antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| tmrB |
ARO:3003059 |
1 |
nucleoside antibiotic |
reduced permeability to antibiotic |
tunicamycin resistance protein |
| vanY gene in vanM cluster |
ARO:3002961 |
22,487 |
glycopeptide antibiotic |
antibiotic target alteration |
vanY; glycopeptide resistance gene cluster |
| catP |
ARO:3002686 |
1 |
phenicol antibiotic |
antibiotic inactivation |
chloramphenicol acetyltransferase (CAT) |
| catQ |
ARO:3002687 |
83 |
phenicol antibiotic |
antibiotic inactivation |
chloramphenicol acetyltransferase (CAT) |
| PC1 beta-lactamase (blaZ) |
ARO:3000621 |
8 |
penam |
antibiotic inactivation |
BlaZ beta-lactamase |
| mphK |
ARO:3004541 |
1 |
macrolide antibiotic |
antibiotic inactivation |
macrolide phosphotransferase (MPH) |
| Bla2 |
ARO:3004189 |
1 |
carbapenem; cephalosporin; penam |
antibiotic inactivation |
subclass B1 Bacillus anthracis Bla beta-lactamase |
| qacG |
ARO:3007015 |
8 |
disinfecting agents and antiseptics |
antibiotic efflux |
small multidrug resistance (SMR) antibiotic efflux pump |
| catI |
ARO:3002683 |
1 |
phenicol antibiotic |
antibiotic inactivation |
chloramphenicol acetyltransferase (CAT) |
| sdrM |
ARO:3007013 |
3 |
fluoroquinolone antibiotic; disinfecting agents and antiseptics |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| tet(M) |
ARO:3000186 |
10,790 |
tetracycline antibiotic |
antibiotic target protection |
tetracycline-resistant ribosomal protection protein |
| qacJ |
ARO:3007014 |
7 |
disinfecting agents and antiseptics |
antibiotic efflux |
small multidrug resistance (SMR) antibiotic efflux pump |
| mdeA |
ARO:3007011 |
1 |
fluoroquinolone antibiotic; aminoglycoside antibiotic; penam; tetracycline antibiotic; disinfecting agents and antiseptics |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| sepA |
ARO:3007012 |
2 |
disinfecting agents and antiseptics |
antibiotic efflux |
small multidrug resistance (SMR) antibiotic efflux pump |
| FosBx1 |
ARO:3007372 |
5 |
phosphonic acid antibiotic |
antibiotic inactivation |
fosfomycin thiol transferase |
| mgrA |
ARO:3000815 |
1 |
fluoroquinolone antibiotic; cephalosporin; penam; tetracycline antibiotic; peptide antibiotic; disinfecting agents and antiseptics |
antibiotic efflux |
ATP-binding cassette (ABC) antibiotic efflux pump; major facilitator superfamily (MFS) antibiotic efflux pump |
| mel |
ARO:3000616 |
115 |
macrolide antibiotic; streptogramin antibiotic |
antibiotic target protection |
msr-type ABC-F protein |
| TEM-116 |
ARO:3000979 |
5 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| mefE |
ARO:3000614 |
786 |
macrolide antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| vanY gene in vanF cluster |
ARO:3002958 |
22 |
glycopeptide antibiotic |
antibiotic target alteration |
vanY; glycopeptide resistance gene cluster |
| vanY gene in vanG cluster |
ARO:3002959 |
34 |
glycopeptide antibiotic |
antibiotic target alteration |
vanY; glycopeptide resistance gene cluster |
| tet(L) |
ARO:3000179 |
4 |
tetracycline antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| BcI |
ARO:3002877 |
20 |
cephalosporin; penem |
antibiotic inactivation |
class A Bacillus cereus Bc beta-lactamase |
| RlmA(II) |
ARO:3001301 |
36,031 |
macrolide antibiotic; lincosamide antibiotic |
antibiotic target alteration |
non-erm 23S ribosomal RNA methyltransferase (G748) |
| vanW gene in vanI cluster |
ARO:3003724 |
36 |
glycopeptide antibiotic |
antibiotic target alteration |
vanW; glycopeptide resistance gene cluster |
| catA8 |
ARO:3004658 |
1 |
phenicol antibiotic |
antibiotic inactivation |
chloramphenicol acetyltransferase (CAT) |
| vanY gene in vanA cluster |
ARO:3002955 |
30 |
glycopeptide antibiotic |
antibiotic target alteration |
vanY; glycopeptide resistance gene cluster |
| tet(K) |
ARO:3000178 |
4 |
tetracycline antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| BcII |
ARO:3002878 |
4 |
cephalosporin; penam |
antibiotic inactivation |
subclass B1 Bacillus cereus Bc beta-lactamase |
| ErmB |
ARO:3000375 |
6,757 |
macrolide antibiotic; lincosamide antibiotic; streptogramin antibiotic; streptogramin A antibiotic; streptogramin B antibiotic |
antibiotic target alteration |
Erm 23S ribosomal RNA methyltransferase |
| vanY gene in vanB cluster |
ARO:3002956 |
14,032 |
glycopeptide antibiotic |
antibiotic target alteration |
vanY; glycopeptide resistance gene cluster |
| lnuA |
ARO:3002835 |
4 |
lincosamide antibiotic |
antibiotic inactivation |
lincosamide nucleotidyltransferase (LNU) |
| AAC(6')-Ie-APH(2'')-Ia bifunctional protein |
ARO:3002597 |
5 |
aminoglycoside antibiotic |
antibiotic inactivation |
aminoglycoside bifunctional resistance protein |
| Bacillus subtilis mprF |
ARO:3003324 |
1 |
peptide antibiotic |
antibiotic target alteration |
defensin resistant mprF |
| adeF |
ARO:3000777 |
1 |
fluoroquinolone antibiotic; tetracycline antibiotic |
antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| vgaALC |
ARO:3002830 |
3 |
lincosamide antibiotic; streptogramin antibiotic; streptogramin A antibiotic; pleuromutilin antibiotic |
antibiotic target protection |
vga-type ABC-F protein |
| bmr |
ARO:3003007 |
1 |
fluoroquinolone antibiotic; nucleoside antibiotic; phenicol antibiotic; disinfecting agents and antiseptics |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| FosB |
ARO:3000172 |
27 |
phosphonic acid antibiotic |
antibiotic inactivation |
fosfomycin thiol transferase |
| rsmA |
ARO:3005069 |
1 |
fluoroquinolone antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic |
antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| Limosilactobacillus reuteri cat-TC |
ARO:3002671 |
10 |
phenicol antibiotic |
antibiotic inactivation |
chloramphenicol acetyltransferase (CAT) |
| tet(U) |
ARO:3004650 |
2 |
tetracycline antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| Streptococcus suis chloramphenicol acetyltransferase |
ARO:3004455 |
1,330 |
phenicol antibiotic |
antibiotic inactivation |
chloramphenicol acetyltransferase (CAT) |
| qacA |
ARO:3003046 |
3 |
fluoroquinolone antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| ANT(9)-Ib |
ARO:3007401 |
4 |
aminoglycoside antibiotic |
antibiotic inactivation |
ANT(9) |
| Streptococcus pneumoniae PBP1a conferring resistance to amoxicillin |
ARO:3003041 |
1,453 |
cephalosporin; cephamycin; penam |
antibiotic target alteration |
Penicillin-binding protein mutations conferring resistance to beta-lactam antibiotics |
| Streptococcus pneumoniae PBP2b conferring resistance to amoxicillin |
ARO:3003042 |
1,983 |
cephalosporin; cephamycin; penam |
antibiotic target alteration |
Penicillin-binding protein mutations conferring resistance to beta-lactam antibiotics |
| vanU gene in vanG cluster |
ARO:3004253 |
2 |
glycopeptide antibiotic |
antibiotic target alteration |
glycopeptide resistance gene cluster; vanU |
| msrA |
ARO:3000251 |
1 |
macrolide antibiotic; streptogramin antibiotic; streptogramin B antibiotic |
antibiotic target protection |
msr-type ABC-F protein |
| ErmC |
ARO:3000250 |
3 |
macrolide antibiotic; lincosamide antibiotic; streptogramin antibiotic; streptogramin A antibiotic; streptogramin B antibiotic |
antibiotic target alteration |
Erm 23S ribosomal RNA methyltransferase |
| Streptococcus pneumoniae PBP2x conferring resistance to amoxicillin |
ARO:3003043 |
4,568 |
cephalosporin; cephamycin; penam |
antibiotic target alteration |
Penicillin-binding protein mutations conferring resistance to beta-lactam antibiotics |
| Bla1 |
ARO:3000090 |
1 |
penam |
antibiotic inactivation |
class A Bacillus anthracis Bla beta-lactamase |
| vanG |
ARO:3002909 |
2 |
glycopeptide antibiotic |
antibiotic target alteration |
glycopeptide resistance gene cluster; Van ligase |
| aad(6) |
ARO:3002628 |
6 |
aminoglycoside antibiotic |
antibiotic inactivation |
ANT(6) |