|
Ata
|
ata
|
0.0001156 |
3 |
VF1333
|
Adherence |
(ata) trimeric autotransporter adhesin Ata [Ata (VF1333) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU]
|
|
Alpha-hemolysin
|
hly/hla
|
0.0000385 |
1 |
VF0001
|
Exotoxin |
(hly/hla) Alpha-Hemolysin precursor [Alpha-hemolysin (VF0001) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus MW2]
|
|
TFP
|
pilJ
|
0.0001927 |
4 |
VF1334
|
Adherence |
(pilP) pilus assembly protein PilP [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU]
|
|
Capsule
|
cap8F
|
0.0015801 |
32 |
VF0003
|
Immune modulation |
(cap8J) type 8 capsular polysaccharide synthesis protein Cap8J [Capsule (VF0003) - Immune modulation (VFC0258)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Hyaluronic acid capsule
|
hasB
|
1.0745366 |
25,933 |
VF0244
|
Immune modulation |
(hasB) UDP-glucose 6-dehydrogenase HasB [Hyaluronic acid capsule (VF0244) - Immune modulation (VFC0258)] [Streptococcus pyogenes M1 GAS]
|
|
Beta-hemolysin
|
hlb
|
0.0001927 |
5 |
VF0002
|
Exotoxin |
(hlb) beta-hemolysin [Beta-hemolysin (VF0002) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus COL]
|
|
TlyC
|
tlyC
|
0.0000771 |
2 |
VF0489
|
Exoenzyme |
(tlyC) hemolysin C [TlyC (VF0489) - Exoenzyme (VFC0251)] [Rickettsia typhi str. Wilmington]
|
|
Hyaluronidase
|
hylA
|
0.0000385 |
1 |
VF0246
|
Exoenzyme |
(hylA) hyaluronidase [Hyaluronidase (VF0246) - Exoenzyme (VFC0251)] [Streptococcus pyogenes M1 GAS]
|
|
LPS
|
pgm
|
0.000501 |
13 |
VF0367
|
Immune modulation |
(acpXL) acyl carrier protein [LPS (VF0367) - Immune modulation (VFC0258)] [Brucella melitensis bv. 1 str. 16M]
|
|
ESX-3
|
PE5
|
0.0001927 |
3 |
VF0521
|
Effector delivery system |
(eccA3) Type VII secretion system protein EccA3 [ESX-3 (VF0521) - Effector delivery system (VFC0086)] [Mycobacterium tuberculosis H37Rv]
|
|
Type VII secretion system
|
esaB
|
0.0007708 |
13 |
VF0403
|
Effector delivery system |
(esaB) type VII secretion system protein EsaB [Type VII secretion system (VF0403) - Effector delivery system (VFC0086)] [Staphylococcus aureus subsp. aureus MW2]
|
|
PavB
|
pavB/pfbB
|
1.9051528 |
25,465 |
VF0524
|
Adherence |
(pavB/pfbB) cell wall surface anchor family protein, Plasminogen- and Fibronectin-binding protein B [PavB (VF0524) - Adherence (VFC0001)] [Streptococcus pneumoniae R6]
|
|
T2SS
|
gspE2
|
0.0000385 |
1 |
VF1335
|
Effector delivery system |
(gspE2) putative secretion pathway ATPase [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU]
|
|
Staphopain
|
sspB
|
0.0002312 |
3 |
VF0006
|
Exoenzyme |
(sspB) staphopain cysteine proteinase SspB [Staphopain (VF0006) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus MW2]
|
|
ACF
|
acfB
|
0.0000385 |
1 |
VF0127
|
Others |
(acfB) accessory colonization factor AcfB [ACF (VF0127) - Others (VFC0346)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
ESX-5
|
Rv1794
|
0.0000771 |
1 |
VF0402
|
Effector delivery system |
(PE18) PE family protein PE18 [ESX-5 (VF0402) - Effector delivery system (VFC0086)] [Mycobacterium tuberculosis H37Rv]
|
|
SpaP
|
spaP/pac
|
0.0006166 |
15 |
VF0526
|
Adherence |
(spaP/pac) cell surface antigen SpaP [SpaP (VF0526) - Adherence (VFC0001)] [Streptococcus mutans UA159]
|
|
PfbA
|
pfbA
|
1.0361506 |
25,787 |
VF0525
|
Adherence |
(pfbA) cell wall surface anchor family protein, Plasminogen- and Fibronectin-binding protein A [PfbA (VF0525) - Adherence (VFC0001)] [Streptococcus pneumoniae R6]
|
|
Sulfolipid-1 biosynthesis and transport
|
pks2
|
0.0001156 |
3 |
VF0803
|
Immune modulation |
(mmpL8) integral membrane transport protein MmpL8 [Sulfolipid-1 biosynthesis and transport (VF0803) - Immune modulation (VFC0258)] [Mycobacterium tuberculosis H37Rv]
|
|
PI-2a
|
pilB
|
0.0000385 |
1 |
VF0528
|
Adherence |
(pilB) major subunit PilB [PI-2a (VF0528) - Adherence (VFC0001)] [Streptococcus agalactiae NEM316]
|
|
AI-2
|
luxS
|
0.0000385 |
1 |
VF0406
|
Biofilm |
(luxS) S-ribosylhomocysteinase [AI-2 (VF0406) - Biofilm (VFC0271)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
PI-1
|
srtC1
|
0.0000385 |
1 |
VF0527
|
Adherence |
(srtC1) class C sortase [PI-1 (VF0527) - Adherence (VFC0001)] [Streptococcus agalactiae NEM316]
|
|
RlrA islet
|
srtC-2/srtC
|
1.4445986 |
6,597 |
VF0529
|
Adherence |
(srtC-3/srtD) sortase [RlrA islet (VF0529) - Adherence (VFC0001)] [Streptococcus pneumoniae TIGR4]
|
|
Type IV pili
|
vfr
|
0.0011177 |
4 |
VF0082
|
Adherence |
(pilH) twitching motility protein PilH [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1]
|
|
LPS
|
wbpI
|
0.0002698 |
2 |
VF0085
|
Immune modulation |
(wbpM) nucleotide sugar epimerase/dehydratase WbpM [LPS (VF0085) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1]
|
|
Xcp secretion system
|
xcpQ
|
0.0001927 |
2 |
VF0084
|
Effector delivery system |
(xcpR) general secretion pathway protein E [Xcp secretion system (VF0084) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
BopD
|
bopD
|
0.0001542 |
4 |
VF0362
|
Biofilm |
(bopD) sugar-binding transcriptional regulator, LacI family [BopD (VF0362) - Biofilm (VFC0271)] [Enterococcus faecalis V583]
|
|
Capsule
|
cpsB/cdsA
|
0.5887771 |
11,168 |
VF0361
|
Immune modulation |
(cpsB/cdsA) phosphatidate cytidylyltransferase [Capsule (VF0361) - Immune modulation (VFC0258)] [Enterococcus faecalis V583]
|
|
RtxA
|
rtxB
|
0.0001156 |
3 |
VF0482
|
Exotoxin |
(rtxE) RTX toxin transporter, ATPase protein [RtxA (VF0482) - Exotoxin (VFC0235)] [Aeromonas hydrophila subsp. hydrophila ATCC 7966]
|
|
LOS
|
rfaK
|
0.0000771 |
1 |
VF0078
|
Immune modulation |
(rfaK) glycosyltransferase family 4 protein [LOS (VF0078) - Immune modulation (VFC0258)] [Neisseria meningitidis MC58]
|
|
AS
|
EF0485
|
0.0000385 |
1 |
VF0352
|
Adherence |
(EF0485) aggregation substance [AS (VF0352) - Adherence (VFC0001)] [Enterococcus faecalis V583]
|
|
GroEL
|
groEL
|
1.0053956 |
25,941 |
VF0594
|
Adherence |
(groEL) chaperonin GroEL [GroEL (VF0594) - Adherence (VFC0001)] [Clostridium difficile 630]
|
|
Polar flagella
|
flmH
|
0.0002698 |
7 |
VF0473
|
Motility |
(flmH) short chain dehydrogenase/reductase family oxidoreductase [Polar flagella (VF0473) - Motility (VFC0204)] [Aeromonas hydrophila ML09-119]
|
|
Tap type IV pili
|
tapT
|
0.0000771 |
2 |
VF0475
|
Adherence |
(tapT) twitching ATPase [Tap type IV pili (VF0475) - Adherence (VFC0001)] [Aeromonas hydrophila ML09-119]
|
|
EfaA
|
efaA
|
0.0000385 |
1 |
VF0354
|
Adherence |
(efaA) endocarditis specific antigen [EfaA (VF0354) - Adherence (VFC0001)] [Enterococcus faecalis V583]
|
|
Exe T2SS
|
exeG
|
0.0000385 |
1 |
VF0478
|
Effector delivery system |
(exeG) general secretion pathway protein G [Exe T2SS (VF0478) - Effector delivery system (VFC0086)] [Aeromonas hydrophila ML09-119]
|
|
Flagella
|
flhG
|
0.0002698 |
6 |
VF0114
|
Motility |
(flhG) ATP-binding protein [Flagella (VF0114) - Motility (VFC0204)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
|
|
Flagella
|
flaD
|
0.0000771 |
2 |
VF0519
|
Motility |
(flgO) Vibrio-specific flagellar H-ring component FlgO [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
ClpC
|
clpC
|
0.0063977 |
109 |
VF0072
|
Stress survival |
(clpC) endopeptidase Clp ATP-binding chain C [ClpC (VF0072) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
|
|
ClpP
|
clpP
|
1.0041623 |
25,936 |
VF0074
|
Stress survival |
(clpP) ATP-dependent Clp protease proteolytic subunit [ClpP (VF0074) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
|
|
ClpE
|
clpE
|
0.0044321 |
107 |
VF0073
|
Stress survival |
(clpE) ATP-dependent protease [ClpE (VF0073) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
|
|
Opa
|
opa
|
0.0000771 |
1 |
VF0076
|
Invasion |
(opa) outer membrane beta-barrel protein [Opa (VF0076) - Invasion (VFC0083)] [Neisseria meningitidis MC58]
|
|
PNAG
|
pgaC
|
0.0000385 |
1 |
VF0472
|
Biofilm |
(pgaC) poly-beta-1,6 N-acetyl-D-glucosamine synthase [PNAG (VF0472) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU]
|
|
Capsule
|
SP_RS01735
|
4.4570085 |
24,670 |
VF0144
|
Immune modulation |
(cps4G) capsular polysaccharide biosynthesis protein Cps4G [Capsule (VF0144) - Immune modulation (VFC0258)] [Streptococcus pneumoniae TIGR4]
|
|
V8 protease
|
sspA
|
0.0001156 |
3 |
VF0023
|
Exoenzyme |
(sspA) serine protease; V8 protease; glutamyl endopeptidase [V8 protease (VF0023) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Autolysin
|
lytA
|
3.3987359 |
25,933 |
VF0143
|
Exoenzyme |
(cbpD) choline binding protein D [Autolysin (VF0143) - Exoenzyme (VFC0251)] [Streptococcus pneumoniae TIGR4]
|
|
Kappa-toxin
|
colA
|
0.000501 |
10 |
VF0388
|
Exoenzyme |
(colA) collagenase [Kappa-toxin (VF0388) - Exoenzyme (VFC0251)] [Clostridium perfringens str. 13]
|
|
Tbp
|
tbpA
|
0.0001927 |
3 |
VF0267
|
Nutritional/Metabolic factor |
(tbpA) transferrin-binding protein 1 precursor [Tbp (VF0267) - Nutritional/Metabolic factor (VFC0272)] [Haemophilus influenzae Rd KW20]
|
|
LPS
|
wbtL
|
0.534821 |
13,811 |
VF0542
|
Immune modulation |
(wbtB) galactosyl transferase [LPS (VF0542) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
Hyaluronidase
|
hysA
|
1.1738159 |
25,628 |
VF0146
|
Exoenzyme |
(hysA) hyaluronidase [Hyaluronidase (VF0146) - Exoenzyme (VFC0251)] [Streptococcus pneumoniae TIGR4]
|
|
CBPs
|
cbpG
|
1.8683856 |
25,930 |
VF0145
|
Adherence |
(pce/cbpE) choline binding protein E [CBPs (VF0145) - Adherence (VFC0001)] [Streptococcus pneumoniae TIGR4]
|
|
Aureolysin
|
aur
|
0.0000771 |
2 |
VF0024
|
Exoenzyme |
(aur) zinc metalloproteinase aureolysin [Aureolysin (VF0024) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus MW2]
|
|
VWbp
|
vWbp
|
0.0000385 |
1 |
VF0420
|
Exoenzyme |
(vWbp) secreted von Willebrand factor-binding protein precursor [VWbp (VF0420) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus str. Newman]
|
|
Nitrate reductase
|
narH
|
0.0008479 |
16 |
VF0302
|
Nutritional/Metabolic factor |
(narG) nitrate reductase subunit alpha [Nitrate reductase (VF0302) - Nutritional/Metabolic factor (VFC0272)] [Mycobacterium tuberculosis H37Rv]
|
|
HxuABC
|
hxuB
|
0.0002312 |
3 |
VF0269
|
Nutritional/Metabolic factor |
(hxuA) heme-hemopexin utilization protein A, two-partner secretion (TPS) pathway TpsA protein, haem-haemopexin binding protein [HxuABC (VF0269) - Nutritional/Metabolic factor (VFC0272)] [Haemophilus influenzae Rd KW20]
|
|
Neuraminidase
|
nanB
|
0.9886307 |
24,219 |
VF0148
|
Exoenzyme |
(nanB) neuraminidase B [Neuraminidase (VF0148) - Exoenzyme (VFC0251)] [Streptococcus pneumoniae TIGR4]
|
|
Sbi
|
sbi
|
0.0000771 |
1 |
VF0423
|
Immune modulation |
(sbi) IgG-binding protein SBI [Sbi (VF0423) - Immune modulation (VFC0258)] [Staphylococcus aureus subsp. aureus MW2]
|
|
AdsA
|
adsA
|
0.0001156 |
3 |
VF0422
|
Immune modulation |
(adsA) Adenosine synthase A [AdsA (VF0422) - Immune modulation (VFC0258)] [Staphylococcus aureus subsp. aureus MW2]
|
|
HitABC
|
hitC
|
0.0001156 |
3 |
VF0268
|
Nutritional/Metabolic factor |
(hitC) iron(III) ABC transporter, ATP-binding protein [HitABC (VF0268) - Nutritional/Metabolic factor (VFC0272)] [Haemophilus influenzae Rd KW20]
|
|
IgA1 protease
|
iga
|
1.1003199 |
22,298 |
VF0147
|
Immune modulation |
(zmpC) immunoglobulin A1 protease [IgA1 protease (VF0147) - Immune modulation (VFC0258)] [Streptococcus pneumoniae TIGR4]
|
|
Capsule
|
galE
|
0.0129109 |
324 |
VF0543
|
Immune modulation |
(galE) UDP-glucose 4-epimerase GalE [Capsule (VF0543) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
Mu-toxin
|
nagH
|
0.0000385 |
1 |
VF0389
|
Exoenzyme |
(nagH) hyaluronidase [Mu-toxin (VF0389) - Exoenzyme (VFC0251)] [Clostridium perfringens str. 13]
|
|
Pneumolysin
|
ply
|
1.0338767 |
25,925 |
VF0149
|
Exotoxin |
(ply) pneumolysin [Pneumolysin (VF0149) - Exotoxin (VFC0235)] [Streptococcus pneumoniae TIGR4]
|
|
KatG
|
katG
|
0.0000385 |
1 |
VF0303
|
Stress survival |
(katG) catalase-peroxidase [KatG (VF0303) - Stress survival (VFC0282)] [Mycobacterium tuberculosis H37Rv]
|
|
HSI-3
|
PA2359
|
0.0000385 |
1 |
VF0944
|
Effector delivery system |
(PA2359) transcriptional regulator [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
HSI-2
|
tssJ
|
0.0007323 |
3 |
VF0943
|
Effector delivery system |
(PA1663) transcriptional regulator [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
T6SS-1
|
BPS_RS26875
|
0.0001927 |
5 |
VF0429
|
Effector delivery system |
(BPS_RS26875) response regulator VirG [T6SS-1 (VF0429) - Effector delivery system (VFC0086)] [Burkholderia pseudomallei K96243]
|
|
PDIM
|
fadD29
|
0.0006937 |
5 |
VF0309
|
Immune modulation |
(ddrA) daunorubicin ABC transporter ATP-binding protein DrrA [PDIM (VF0309) - Immune modulation (VFC0258)] [Mycobacterium tuberculosis H37Rv]
|
|
CpnT
|
cpnT
|
0.0000385 |
1 |
VF1197
|
Effector delivery system |
(cpnT) NAD+ glycohydrolase [CpnT (VF1197) - Effector delivery system (VFC0086)] [Mycobacterium tuberculosis H37Rv]
|
|
CsrA
|
csrA
|
0.0000385 |
1 |
VF0261
|
Regulation |
(csrA) carbon storage regulator CsrA [CsrA (VF0261) - Regulation (VFC0301)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
SE
|
sec
|
0.0000385 |
1 |
VF0020
|
Exotoxin |
(sec) staphylococcal enterotoxin C precursor [SE (VF0020) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Capsule
|
capB
|
0.0001927 |
3 |
VF0141
|
Immune modulation |
(capB) CapB, involved in Poly-gamma-glutamate synthesis [Capsule (VF0141) - Immune modulation (VFC0258)] [Bacillus anthracis]
|
|
Lipase
|
lip
|
0.0002312 |
4 |
VF0012
|
Exoenzyme |
(lip) triacylglycerol lipase precursor [Lipase (VF0012) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Isocitrate lyase
|
icl
|
0.0023124 |
50 |
VF0253
|
Others |
(icl) Isocitrate lyase Icl (isocitrase) (isocitratase) [Isocitrate lyase (VF0253) - Others (VFC0346)] [Mycobacterium tuberculosis H37Rv]
|
|
Intercellular adhesion proteins
|
icaR
|
0.0001156 |
2 |
VF0014
|
Biofilm |
(icaR) ica operon transcriptional regulator IcaR [Intercellular adhesion proteins (VF0014) - Biofilm (VFC0271)] [Staphylococcus aureus subsp. aureus MW2]
|
|
PI-2
|
sipA
|
0.5401395 |
3,758 |
VF0530
|
Adherence |
(srtG1) sortase, SrtB family [PI-2 (VF0530) - Adherence (VFC0001)] [Streptococcus pneumoniae Taiwan19F-14]
|
|
Hyaluronate lyase
|
hysA
|
0.0000385 |
1 |
VF0013
|
Exoenzyme |
(hysA) hyaluronate lyase precursor [Hyaluronate lyase (VF0013) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Nhe
|
nheB
|
0.0050488 |
41 |
VF0533
|
Exotoxin |
(nheC) non-hemolytic enterotoxin C [Nhe (VF0533) - Exotoxin (VFC0235)] [Bacillus cereus ATCC 10987]
|
|
Eap/Map
|
eap/map
|
0.0000385 |
1 |
VF0016
|
Adherence |
(eap/map) extracellular adherence protein Eap/Map [Eap/Map (VF0016) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
|
|
HBL
|
hblC
|
0.0059737 |
43 |
VF0532
|
Exotoxin |
(hblC) Hemolysin BL lytic component L2 [HBL (VF0532) - Exotoxin (VFC0235)] [Bacillus cereus ATCC 14579]
|
|
Isd
|
harA
|
0.0002312 |
5 |
VF0015
|
Nutritional/Metabolic factor |
(harA) haptoglobin-binding heme uptake protein HarA [Isd (VF0015) - Nutritional/Metabolic factor (VFC0272)] [Staphylococcus aureus subsp. aureus str. Newman]
|
|
SigA
|
sigA/rpoV
|
0.0020812 |
54 |
VF0257
|
Regulation |
(sigA/rpoV) RNA polymerase sigma factor SigA [SigA (VF0257) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
Yersiniabactin
|
ybtA
|
0.0000385 |
1 |
VF0136
|
Nutritional/Metabolic factor |
(ybtA) transcriptional regulator YbtA [Yersiniabactin (VF0136) - Nutritional/Metabolic factor (VFC0272)] [Yersinia pestis CO92]
|
|
CytK
|
cytK
|
0.0015801 |
38 |
VF0535
|
Exotoxin |
(cytK) cytotoxin K [CytK (VF0535) - Exotoxin (VFC0235)] [Bacillus cereus ATCC 10987]
|
|
ALO
|
alo
|
0.0016572 |
36 |
VF0534
|
Exotoxin |
(alo) thiol-activated cytolysin [ALO (VF0534) - Exotoxin (VFC0235)] [Bacillus anthracis str. Sterne]
|
|
RTX protein
|
frpA
|
0.0000385 |
1 |
VF0897
|
Adherence |
(frpA) iron-regulated protein FrpA [RTX protein (VF0897) - Adherence (VFC0001)] [Neisseria meningitidis MC58]
|
|
InhA
|
BAS_RS06430
|
0.0075924 |
50 |
VF0536
|
Exoenzyme |
(BAS_RS06430) immune inhibitor A [InhA (VF0536) - Exoenzyme (VFC0251)] [Bacillus anthracis str. Sterne]
|
|
SDr
|
sdrE
|
0.0002312 |
4 |
VF0019
|
Adherence |
(sdrC) Ser-Asp rich fibrinogen-binding bone sialoprotein-binding protein [SDr (VF0019) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Alginate
|
algK
|
0.0006937 |
7 |
VF0091
|
Biofilm |
(algQ) Alginate regulatory protein AlgQ [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1]
|
|
Pyoverdine
|
pvdD
|
0.0001156 |
3 |
VF0094
|
Nutritional/Metabolic factor |
(pvdD) pyoverdine synthetase D [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1]
|
|
Quorum sensing
|
lasR
|
0.0000385 |
1 |
VF0093
|
Biofilm |
(lasR) transcriptional regulator LasR [Quorum sensing (VF0093) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1]
|
|
FnBPs
|
fnbA
|
0.0000771 |
2 |
VF0010
|
Adherence |
(fnbA) fibronectin-binding protein A [FnBPs (VF0010) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
|
|
OatA
|
oatA
|
0.0000385 |
1 |
VF0441
|
Immune modulation |
(oatA) peptidoglycan O-acetyltransferase [OatA (VF0441) - Immune modulation (VFC0258)] [Listeria monocytogenes EGD-e]
|
|
RelA
|
relA
|
0.0002312 |
6 |
VF0287
|
Regulation |
(relA) Probable GTP pyrophosphokinase RelA (ATP:GTP 3'-pyrophosphotransferase) (PPGPP synthetase I) ((P)PPGPP synthetase) (GTP diphosphokinase) [RelA (VF0287) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
IgA1 protease
|
iga1
|
0.0000385 |
1 |
VF0045
|
Exoenzyme |
(iga1) immunoglobin A1 protease [IgA1 protease (VF0045) - Exoenzyme (VFC0251)] [Haemophilus influenzae Rd KW20]
|
|
RpoS
|
rpoS
|
0.0000771 |
2 |
VF0166
|
Regulation |
(rpoS) RNA polymerase sigma factor RpoS [RpoS (VF0166) - Regulation (VFC0301)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Phospholipase C
|
plcC
|
0.0000771 |
2 |
VF0320
|
Exotoxin |
(plcC) phospholipase C [Phospholipase C (VF0320) - Exotoxin (VFC0235)] [Mycobacterium tuberculosis H37Rv]
|
|
PhoP
|
phoR
|
0.0000385 |
1 |
VF0286
|
Regulation |
(phoR) Possible two component system response sensor kinase membrane associated PhoR [PhoP (VF0286) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
LOS
|
rfaD
|
0.4356573 |
11,214 |
VF0044
|
Immune modulation |
(msbA) lipid transporter ATP-binding/permease [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20]
|
|
KatAB
|
katA
|
0.0001542 |
4 |
VF0168
|
Stress survival |
(katA) catalase/(hydro)peroxidase [KatAB (VF0168) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Ybt
|
irp2
|
0.0000771 |
1 |
VF0564
|
Nutritional/Metabolic factor |
(fyuA) yersiniabactin receptor FyuA [Ybt (VF0564) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Lap
|
lap
|
0.0077466 |
171 |
VF0444
|
Adherence |
(lap) Listeria adhesion protein Lap [Lap (VF0444) - Adherence (VFC0001)] [Listeria monocytogenes EGD-e]
|
|
Capsule
|
glf
|
0.039388 |
1,018 |
VF0323
|
Immune modulation |
(kfiD) UDP-glucose 6-dehydrogenase [Capsule (VF0323) - Immune modulation (VFC0258)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
|
|
SodB
|
sodB
|
0.0001927 |
4 |
VF0169
|
Stress survival |
(sodB) superoxide dismutase [SodB (VF0169) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
LOS
|
Cj1136
|
0.0001927 |
5 |
VF0326
|
Immune modulation |
(Cj1138) glycosyltransferase [LOS (VF0326) - Immune modulation (VFC0258)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
|
|
AcrAB
|
acrA
|
0.0001927 |
2 |
VF0568
|
Antimicrobial activity/Competitive advantage |
(acrB) acriflavine resistance protein B [AcrAB (VF0568) - Antimicrobial activity/Competitive advantage (VFC0325)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Curli fibers
|
csgB
|
0.0000385 |
1 |
VF1138
|
Adherence |
(csgB) curlin minor subunit CsgB [Curli fibers (VF1138) - Adherence (VFC0001)] [Escherichia coli O25b:H4-ST131]
|
|
PEB1
|
pebA
|
0.0001542 |
4 |
VF0327
|
Adherence |
(pebA) bifunctional adhesin/ABC transporter aspartate/glutamate-binding protein [PEB1 (VF0327) - Adherence (VFC0001)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
|
|
FeoAB
|
feoB
|
0.0000771 |
2 |
VF0160
|
Nutritional/Metabolic factor |
(feoB) ferrous iron transporter B [FeoAB (VF0160) - Nutritional/Metabolic factor (VFC0272)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
PavA
|
pavA
|
1.0026593 |
25,933 |
VF0283
|
Adherence |
(pavA) Fibronectin-binding protein-like protein A [PavA (VF0283) - Adherence (VFC0001)] [Streptococcus pneumoniae R6]
|
|
OapA
|
oapA
|
0.0000771 |
2 |
VF0040
|
Adherence |
(oapA) opacity associated protein (oapA) [OapA (VF0040) - Adherence (VFC0001)] [Haemophilus influenzae Rd KW20]
|
|
Capsule
|
rfbK1
|
1.0129109 |
25,933 |
VF0560
|
Immune modulation |
(gndA) NADP-dependent phosphogluconate dehydrogenase [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
P2 protein
|
ompP2
|
0.0000771 |
2 |
VF0042
|
Immune modulation |
(ompP2) outer membrane protein P2 (ompP2), laminin binding protein [P2 protein (VF0042) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20]
|
|
Flagella
|
fliC
|
0.0000771 |
2 |
VF0430
|
Motility |
(fliC) flagellin [Flagella (VF0430) - Motility (VFC0204)] [Burkholderia pseudomallei K96243]
|
|
Alpha-C protein
|
bca
|
0.0000385 |
1 |
VF0276
|
Invasion |
(bca) C protein alpha-antigen [Alpha-C protein (VF0276) - Invasion (VFC0083)] [Streptococcus agalactiae A909]
|
|
Lmb
|
lmb
|
1.0017343 |
25,919 |
VF0275
|
Adherence |
(lmb) laminin-binding surface protein [Lmb (VF0275) - Adherence (VFC0001)] [Streptococcus agalactiae NEM316]
|
|
FupA
|
feoB
|
0.0001156 |
3 |
VF0550
|
Nutritional/Metabolic factor |
(feoB) Fe(2+) transporter permease subunit FeoB [FupA (VF0550) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
Flagella
|
fliC
|
0.0000771 |
2 |
VF0157
|
Motility |
(fleQ) transcriptional regulator FleQ [Flagella (VF0157) - Motility (VFC0204)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Antigen 85
|
fbpD
|
0.0000385 |
1 |
VF0311
|
Adherence |
(fbpD) MPT51/MPB51 antigen [Antigen 85 (VF0311) - Adherence (VFC0001)] [Mycobacterium tuberculosis H37Rv]
|
|
Beta-C protein
|
cba
|
0.0040467 |
93 |
VF0277
|
Immune modulation |
(cba) c protein beta antigen [Beta-C protein (VF0277) - Immune modulation (VFC0258)] [Streptococcus agalactiae FM027022]
|
|
Hsp60
|
htpB
|
0.0001927 |
5 |
VF0159
|
Adherence |
(htpB) Hsp60, 60K heat shock protein HtpB [Hsp60 (VF0159) - Adherence (VFC0001)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
HMW1/HMW2
|
hmw2A
|
0.0002312 |
2 |
VF0038
|
Adherence |
(hmw2A) adhesin HMW2A, two-partner secretion (TPS) pathway TpsA exoprotein [HMW1/HMW2 (VF0038) - Adherence (VFC0001)] [Haemophilus influenzae str. 12]
|
|
Hap
|
hap
|
0.0000771 |
1 |
VF0037
|
Adherence |
(hap) adhesion and penetration protein Hap [Hap (VF0037) - Adherence (VFC0001)] [Haemophilus influenzae N187]
|
|
Beta-haemolysin/cytolysin
|
cylG
|
0.0000385 |
1 |
VF0279
|
Exotoxin |
(cylG) 3-ketoacyl-ACP-reductase CylG [Beta-haemolysin/cytolysin (VF0279) - Exotoxin (VFC0235)] [Streptococcus agalactiae NEM316]
|
|
ESX-1
|
espA
|
0.0000385 |
1 |
VF0315
|
Effector delivery system |
(espA) ESX-1 type VII secretion system EspA [ESX-1 (VF0315) - Effector delivery system (VFC0086)] [Mycobacterium tuberculosis H37Rv]
|
|
Pyrimidine biosynthesis
|
carB
|
0.0017343 |
40 |
VF0558
|
Nutritional/Metabolic factor |
(carB) carbamoyl phosphate synthase large subunit [Pyrimidine biosynthesis (VF0558) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
LAM
|
aftB
|
0.0000385 |
1 |
VF0318
|
Immune modulation |
(aftB) terminal beta-(1->2)-arabinofuranosyltransferase [LAM (VF0318) - Immune modulation (VFC0258)] [Mycobacterium tuberculosis H37Rv]
|
|
Hgp
|
hgpB
|
0.0002312 |
5 |
VF0270
|
Nutritional/Metabolic factor |
(hgpB) TonB-dependent hemoglobin/transferrin/lactoferrin family receptor [Hgp (VF0270) - Nutritional/Metabolic factor (VFC0272)] [Haemophilus influenzae Rd KW20]
|
|
Sialidase
|
nanI
|
0.0000385 |
1 |
VF0391
|
Exoenzyme |
(nanI) exo-alpha-sialidase [Sialidase (VF0391) - Exoenzyme (VFC0251)] [Clostridium perfringens ATCC 13124]
|
|
PsaA
|
psaA
|
1.001426 |
25,932 |
VF0151
|
Nutritional/Metabolic factor |
(psaA) manganese ABC transporter, manganese-binding adhesion liprotein [PsaA (VF0151) - Nutritional/Metabolic factor (VFC0272)] [Streptococcus pneumoniae TIGR4]
|
|
O-antigen
|
YE_RS15425
|
0.0003469 |
9 |
VF0392
|
Immune modulation |
(YE_RS15425) GDP-L-fucose synthase [O-antigen (VF0392) - Immune modulation (VFC0258)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
CbpA/PspC
|
cbpA/pspC
|
1.1916214 |
22,272 |
VF0150
|
Adherence |
(cbpA/pspC) choline binding protein A [CbpA/PspC (VF0150) - Adherence (VFC0001)] [Streptococcus pneumoniae TIGR4]
|
|
Capsule
|
GBS_RS06580
|
0.169615 |
3,523 |
VF0274
|
Immune modulation |
(GBS_RS06585) UDP-N-acetylglucosamine--LPS N-acetylglucosamine transferase [Capsule (VF0274) - Immune modulation (VFC0258)] [Streptococcus agalactiae NEM316]
|
|
PspA
|
pspA
|
0.8484218 |
14,407 |
VF0152
|
Immune modulation |
(pspA) surface protein A [PspA (VF0152) - Immune modulation (VFC0258)] [Streptococcus pneumoniae TIGR4]
|
|
Flagella
|
motD
|
0.0016187 |
3 |
VF0273
|
Motility |
(PA1458) two-component sensor [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1]
|
|
Flagella
|
flgL
|
0.0000771 |
2 |
VF0394
|
Motility |
(flgL) flagellar hook-associated protein 3 FlgL [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
Petrobactin
|
asbE
|
0.0081705 |
34 |
VF0584
|
Nutritional/Metabolic factor |
(asbF) petrobactin biosynthesis 3-dehydroshikimate dehydratase AsbF [Petrobactin (VF0584) - Nutritional/Metabolic factor (VFC0272)] [Bacillus anthracis str. Sterne]
|
|
BfmRS
|
bfmS
|
0.0000771 |
2 |
VF0463
|
Regulation |
(bfmS) signal transduction histidine kinase [BfmRS (VF0463) - Regulation (VFC0301)] [Acinetobacter baumannii ACICU]
|
|
Type 1 fimbriae
|
fimD
|
0.0000771 |
1 |
VF0221
|
Adherence |
(fimB) Type 1 fimbriae Regulatory protein fimB [Type 1 fimbriae (VF0221) - Adherence (VFC0001)] [Escherichia coli CFT073]
|
|
Cereulide
|
cesH
|
0.0001927 |
4 |
VF0583
|
Exotoxin |
(cesH) hydrolase, alpha/beta superfamily, CesH [Cereulide (VF0583) - Exotoxin (VFC0235)] [Bacillus cereus AH187]
|
|
P fimbriae
|
papC
|
0.0000385 |
1 |
VF0220
|
Adherence |
(papC) usher protein PapC [P fimbriae (VF0220) - Adherence (VFC0001)] [Escherichia coli CFT073]
|
|
Bacillibactin
|
dhbF
|
0.0102517 |
41 |
VF0586
|
Nutritional/Metabolic factor |
(dhbE) 2,3-dihydroxybenzoate adenylase DhbE [Bacillibactin (VF0586) - Nutritional/Metabolic factor (VFC0272)] [Bacillus cereus ATCC 10987]
|
|
Capsule
|
galE
|
0.0003083 |
8 |
VF0465
|
Immune modulation |
(galE) UDP-glucose 4-epimerase GalE [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU]
|
|
Type 1 fimbriae
|
fimD
|
0.0000385 |
1 |
VF0102
|
Adherence |
(fimD) usher protein FimD [Type 1 fimbriae (VF0102) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
IlsA
|
ilsA
|
0.0021582 |
35 |
VF0585
|
Nutritional/Metabolic factor |
(ilsA) NEAT domain-containing leucine-rich repeat protein [IlsA (VF0585) - Nutritional/Metabolic factor (VFC0272)] [Bacillus cereus ATCC 10987]
|
|
Alpha-Hemolysin
|
hlyB
|
0.0125641 |
299 |
VF0225
|
Exotoxin |
(hlyB) Hemolysin B [Alpha-Hemolysin (VF0225) - Exotoxin (VFC0235)] [Escherichia coli CFT073]
|
|
Acinetobactin
|
basC
|
0.0001542 |
3 |
VF0467
|
Nutritional/Metabolic factor |
(basG) acinetobactin biosynthesis protein BasF [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU]
|
|
Hal
|
hal
|
0.0012333 |
29 |
VF0587
|
Nutritional/Metabolic factor |
(hal) heme-acquisition leucine-rich repeat protein [Hal (VF0587) - Nutritional/Metabolic factor (VFC0272)] [Bacillus anthracis str. Sterne]
|
|
MgtB
|
mgtB
|
0.0004239 |
10 |
VF0106
|
Nutritional/Metabolic factor |
(mgtB) Mg2+ transport protein [MgtB (VF0106) - Nutritional/Metabolic factor (VFC0272)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
LplA1
|
lplA1
|
0.0015416 |
38 |
VF0347
|
Nutritional/Metabolic factor |
(lplA1) lipoate protein ligase [LplA1 (VF0347) - Nutritional/Metabolic factor (VFC0272)] [Listeria monocytogenes EGD-e]
|
|
PbpG
|
pbpG
|
0.0000385 |
1 |
VF0468
|
Immune modulation |
(pbpG) D-alanyl-D-alanine endopeptidase PBP7/8 [PbpG (VF0468) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU]
|
|
AdeFGH efflux pump
|
adeG
|
0.0000385 |
1 |
VF0504
|
Biofilm |
(adeG) cation/multidrug efflux pump [AdeFGH efflux pump (VF0504) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU]
|
|
Enterobactin
|
entF
|
0.0001156 |
3 |
VF0228
|
Nutritional/Metabolic factor |
(entF) enterobactin synthase multienzyme complex component, ATP-dependent [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073]
|
|
FbpA
|
fbpA
|
0.0001542 |
3 |
VF0349
|
Adherence |
(fbpA) fibronectin-binding protein [FbpA (VF0349) - Adherence (VFC0001)] [Listeria monocytogenes EGD-e]
|
|
Csu fimbriae
|
csuC
|
0.0000385 |
1 |
VF0461
|
Biofilm |
(csuC) Csu pilus chaperone protein CsuC [Csu fimbriae (VF0461) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU]
|
|
EF-Tu
|
tufA
|
1.0179211 |
25,932 |
VF0460
|
Adherence |
(tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
Colibactin
|
clbD
|
0.0000385 |
1 |
VF0573
|
Exotoxin |
(clbD) colibactin biosynthesis dehydrogenase ClbD [Colibactin (VF0573) - Exotoxin (VFC0235)] [Klebsiella pneumoniae subsp. pneumoniae 1084]
|
|
LPS
|
kdtB
|
0.0001156 |
3 |
VF0056
|
Immune modulation |
(kdtB) lipopolysaccharide core biosynthesis protein [LPS (VF0056) - Immune modulation (VFC0258)] [Helicobacter pylori 26695]
|
|
KatA
|
katA
|
0.0003083 |
8 |
VF0454
|
Stress survival |
(katA) catalase [KatA (VF0454) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
|
|
Mycobactin
|
mbtB
|
0.0009635 |
24 |
VF0299
|
Nutritional/Metabolic factor |
(mbtB) Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) [Mycobactin (VF0299) - Nutritional/Metabolic factor (VFC0272)] [Mycobacterium tuberculosis H37Rv]
|
|
MsrAB
|
msrA/B(pilB
|
0.0019655 |
51 |
VF0456
|
Stress survival |
(msrA/B(pilB)) trifunctional thioredoxin/methionine sulfoxide reductase A/B protein [MsrAB (VF0456) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
|
|
HSI-1
|
clpV1
|
0.0000385 |
1 |
VF0334
|
Effector delivery system |
(clpV1) type VI secretion system AAA+ family ATPase [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
T6SS
|
rhs/PAAR
|
0.0000771 |
2 |
VF0579
|
Effector delivery system |
(rhs/PAAR) Type VI secretion system protein, PAAR family [T6SS (VF0579) - Effector delivery system (VFC0086)] [Shigella sonnei Ss046]
|
|
VPS
|
vpsC
|
0.0000385 |
1 |
VF0615
|
Biofilm |
(vpsC) exopolysaccharide biosynthesis acetyltransferase VpsC [VPS (VF0615) - Biofilm (VFC0271)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
LPS
|
rfbC
|
0.0002312 |
6 |
VF0171
|
Immune modulation |
(LPG_RS03745) aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme [LPS (VF0171) - Immune modulation (VFC0258)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Urease
|
ureG
|
0.0010406 |
17 |
VF0050
|
Stress survival |
(ureG) urease accessory protein (ureG) [Urease (VF0050) - Stress survival (VFC0282)] [Helicobacter pylori 26695]
|
|
CcmC
|
ccmF
|
0.0000385 |
1 |
VF0292
|
Nutritional/Metabolic factor |
(ccmF) cytochrome c heme lyase subunit CcmF [CcmC (VF0292) - Nutritional/Metabolic factor (VFC0272)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
SigF
|
sigF
|
0.0000385 |
1 |
VF0294
|
Regulation |
(sigF) RNA polymerase sigma factor SigF [SigF (VF0294) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
Flagella
|
cheV3
|
0.0001156 |
3 |
VF0051
|
Motility |
(cheV3) chemotaxis coupling protein CheV3 [Flagella (VF0051) - Motility (VFC0204)] [Helicobacter pylori 26695]
|
|
SigH
|
sigH
|
0.0000385 |
1 |
VF0296
|
Regulation |
(sigH) ECF RNA polymerase sigma factor SigH [SigH (VF0296) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|