|
FBPs
|
prtF2
|
4.573543 |
20,539 |
VF0243
|
Adherence |
(sfbX) LPXTG cell wall anchor domain-containing protein [FBPs (VF0243) - Adherence (VFC0001)] [Streptococcus pyogenes MGAS6180]
|
|
IgA1 protease
|
iga1
|
0.0000487 |
1 |
VF0045
|
Exoenzyme |
(iga1) immunoglobin A1 protease [IgA1 protease (VF0045) - Exoenzyme (VFC0251)] [Haemophilus influenzae Rd KW20]
|
|
LOS
|
lsgB
|
0.0002434 |
5 |
VF0044
|
Immune modulation |
(lsgB) sialyltransferase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20]
|
|
M protein
|
emm
|
0.2529821 |
4,834 |
VF0242
|
Immune modulation |
(emm) M protein [M protein (VF0242) - Immune modulation (VFC0258)] [Streptococcus pyogenes M1 GAS]
|
|
Capsule
|
cap8F
|
0.0002434 |
4 |
VF0003
|
Immune modulation |
(cap8D) type 8 capsular polysaccharide synthesis protein Cap8D [Capsule (VF0003) - Immune modulation (VFC0258)] [Staphylococcus aureus subsp. aureus MW2]
|
|
LPS
|
gtrB
|
0.0000487 |
1 |
VF0124
|
Immune modulation |
(gtrB) bactoprenol glucosyl transferase [LPS (VF0124) - Immune modulation (VFC0258)] [Shigella flexneri 2a str. 301]
|
|
C5a peptidase
|
scpA/scpB
|
0.9581771 |
19,526 |
VF0245
|
Adherence |
(scpA/scpB) streptococcal C5a peptidase [C5a peptidase (VF0245) - Adherence (VFC0001)] [Streptococcus pyogenes M1 GAS]
|
|
Hyaluronic acid capsule
|
hasA
|
3.6643459 |
20,539 |
VF0244
|
Immune modulation |
(hasB) UDP-glucose 6-dehydrogenase HasB [Hyaluronic acid capsule (VF0244) - Immune modulation (VFC0258)] [Streptococcus pyogenes M1 GAS]
|
|
Streptokinase
|
ska
|
1.006086 |
20,536 |
VF0247
|
Exoenzyme |
(ska) streptokinase A precursor [Streptokinase (VF0247) - Exoenzyme (VFC0251)] [Streptococcus pyogenes M1 GAS]
|
|
CNA
|
cna
|
0.0000487 |
1 |
VF0005
|
Adherence |
(cna) collagen adhesin precursor [CNA (VF0005) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Hyaluronidase
|
hylA
|
1.0056478 |
20,340 |
VF0246
|
Exoenzyme |
(hylA) hyaluronidase [Hyaluronidase (VF0246) - Exoenzyme (VFC0251)] [Streptococcus pyogenes M1 GAS]
|
|
Clumping factor
|
clfA
|
0.0000974 |
2 |
VF0004
|
Adherence |
(clfA) Clumping factor A, fibrinogen-binding protein [Clumping factor (VF0004) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Lap
|
lap
|
0.0015093 |
28 |
VF0444
|
Adherence |
(lap) Listeria adhesion protein Lap [Lap (VF0444) - Adherence (VFC0001)] [Listeria monocytogenes EGD-e]
|
|
LPS
|
acpXL
|
0.0000487 |
1 |
VF0367
|
Immune modulation |
(acpXL) acyl carrier protein [LPS (VF0367) - Immune modulation (VFC0258)] [Brucella melitensis bv. 1 str. 16M]
|
|
SpeB
|
speB
|
1.0015093 |
20,519 |
VF0249
|
Exoenzyme |
(speB) pyrogenic exotoxin B [SpeB (VF0249) - Exoenzyme (VFC0251)] [Streptococcus pyogenes M1 GAS]
|
|
PavB
|
pavB/pfbB
|
0.0000974 |
2 |
VF0524
|
Adherence |
(pavB/pfbB) cell wall surface anchor family protein, Plasminogen- and Fibronectin-binding protein B [PavB (VF0524) - Adherence (VFC0001)] [Streptococcus pneumoniae R6]
|
|
Type VII secretion system
|
esxA
|
0.0000487 |
1 |
VF0403
|
Effector delivery system |
(esxA) type VII secretion system secreted protein EsxA [Type VII secretion system (VF0403) - Effector delivery system (VFC0086)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Spes
|
speI
|
3.2942694 |
20,533 |
VF0248
|
Exotoxin |
(speH) streptococcal exotoxin H precursor [Spes (VF0248) - Exotoxin (VFC0235)] [Streptococcus pyogenes M1 GAS]
|
|
Staphopain
|
sspB
|
0.0000974 |
2 |
VF0006
|
Exoenzyme |
(sspB) staphopain cysteine proteinase SspB [Staphopain (VF0006) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus MW2]
|
|
PI-1
|
GBS_RS03565
|
0.1655874 |
1,394 |
VF0527
|
Adherence |
(GBS_RS03585) tip adhesin protein [PI-1 (VF0527) - Adherence (VFC0001)] [Streptococcus agalactiae NEM316]
|
|
RlrA islet
|
srtC-2/srtC
|
0.0081796 |
84 |
VF0529
|
Adherence |
(srtC-1/srtB) sortase [RlrA islet (VF0529) - Adherence (VFC0001)] [Streptococcus pneumoniae TIGR4]
|
|
CAMP factor
|
cfa/cfb
|
0.947904 |
19,429 |
VF0280
|
Exotoxin |
(cfa/cfb) cAMP factor [CAMP factor (VF0280) - Exotoxin (VFC0235)] [Streptococcus agalactiae NEM316]
|
|
Capsule
|
ugd
|
0.0004869 |
10 |
VF0560
|
Immune modulation |
(gndA) NADP-dependent phosphogluconate dehydrogenase [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
BopD
|
bopD
|
0.0000487 |
1 |
VF0362
|
Biofilm |
(bopD) sugar-binding transcriptional regulator, LacI family [BopD (VF0362) - Biofilm (VFC0271)] [Enterococcus faecalis V583]
|
|
IdeS
|
ideS/mac
|
1.0254638 |
20,538 |
VF0284
|
Immune modulation |
(ideS/mac) immunoglobulin G-degrading enzyme [IdeS (VF0284) - Immune modulation (VFC0258)] [Streptococcus pyogenes M1 GAS]
|
|
Capsule
|
cpsB/cdsA
|
0.0000974 |
2 |
VF0361
|
Immune modulation |
(cpsB/cdsA) phosphatidate cytidylyltransferase [Capsule (VF0361) - Immune modulation (VFC0258)] [Enterococcus faecalis V583]
|
|
Alpha-C protein
|
bca
|
0.1237159 |
2,502 |
VF0276
|
Invasion |
(bca) C protein alpha-antigen [Alpha-C protein (VF0276) - Invasion (VFC0083)] [Streptococcus agalactiae A909]
|
|
Lmb
|
lmb
|
1.0008277 |
20,534 |
VF0275
|
Adherence |
(lmb) laminin-binding surface protein [Lmb (VF0275) - Adherence (VFC0001)] [Streptococcus agalactiae NEM316]
|
|
SSLs
|
set20
|
0.0000487 |
1 |
VF0990
|
Exotoxin |
(set20) superantigen-like protein SSL5 [SSLs (VF0990) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus MW2]
|
|
GroEL
|
groEL
|
1.0012172 |
20,538 |
VF0594
|
Adherence |
(groEL) chaperonin GroEL [GroEL (VF0594) - Adherence (VFC0001)] [Clostridium difficile 630]
|
|
AS
|
prgB/asc10
|
0.0000487 |
1 |
VF0352
|
Adherence |
(prgB/asc10) aggregation substance PrgB/Asc10 [AS (VF0352) - Adherence (VFC0001)] [Enterococcus faecalis V583]
|
|
C5a peptidase
|
scpA/scpB
|
0.1273674 |
2,482 |
VF0278
|
Adherence |
(scpA/scpB) streptococcal C5a peptidase [C5a peptidase (VF0278) - Adherence (VFC0001)] [Streptococcus agalactiae NEM316]
|
|
Beta-C protein
|
cba
|
0.0000487 |
1 |
VF0277
|
Immune modulation |
(cba) c protein beta antigen [Beta-C protein (VF0277) - Immune modulation (VFC0258)] [Streptococcus agalactiae FM027022]
|
|
Dot/Icm
|
icmX
|
0.0000974 |
1 |
VF0156
|
Effector delivery system |
(icmW) Dot/Icm type IV secretion system chaperone IcmW [Dot/Icm (VF0156) - Effector delivery system (VFC0086)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Hsp60
|
htpB
|
0.0000974 |
2 |
VF0159
|
Adherence |
(htpB) Hsp60, 60K heat shock protein HtpB [Hsp60 (VF0159) - Adherence (VFC0001)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
HMW1/HMW2
|
hmw1C
|
0.0001461 |
1 |
VF0038
|
Adherence |
(hmw1C) glycosyltransferase [HMW1/HMW2 (VF0038) - Adherence (VFC0001)] [Haemophilus influenzae str. 12]
|
|
CD3246
|
CD3246
|
0.0000974 |
1 |
VF0599
|
Adherence |
(CD3246) Cys-Gln thioester bond-forming surface protein [CD3246 (VF0599) - Adherence (VFC0001)] [Clostridium difficile 630]
|
|
Beta-haemolysin/cytolysin
|
cylI
|
0.0000974 |
1 |
VF0279
|
Exotoxin |
(cylF) putative aminomethyltransferase CylF [Beta-haemolysin/cytolysin (VF0279) - Exotoxin (VFC0235)] [Streptococcus agalactiae NEM316]
|
|
Pyrimidine biosynthesis
|
carB
|
0.0001948 |
4 |
VF0558
|
Nutritional/Metabolic factor |
(carB) carbamoyl phosphate synthase large subunit [Pyrimidine biosynthesis (VF0558) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
ClpC
|
clpC
|
0.0000974 |
2 |
VF0072
|
Stress survival |
(clpC) endopeptidase Clp ATP-binding chain C [ClpC (VF0072) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
|
|
PsaA
|
psaA
|
1.0012659 |
20,539 |
VF0151
|
Nutritional/Metabolic factor |
(psaA) manganese ABC transporter, manganese-binding adhesion liprotein [PsaA (VF0151) - Nutritional/Metabolic factor (VFC0272)] [Streptococcus pneumoniae TIGR4]
|
|
ClpP
|
clpP
|
1.0001461 |
20,539 |
VF0074
|
Stress survival |
(clpP) ATP-dependent Clp protease proteolytic subunit [ClpP (VF0074) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
|
|
ClpE
|
clpE
|
0.0008277 |
16 |
VF0073
|
Stress survival |
(clpE) ATP-dependent protease [ClpE (VF0073) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
|
|
Capsule
|
GBS_RS06605
|
0.0000487 |
1 |
VF0274
|
Immune modulation |
(GBS_RS06605) tyrosine-protein phosphatase CpsB [Capsule (VF0274) - Immune modulation (VFC0258)] [Streptococcus agalactiae NEM316]
|
|
BSH
|
bsh
|
0.0000974 |
2 |
VF0350
|
Stress survival |
(bsh) bile salt hydrolase [BSH (VF0350) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
|
|
Flagella
|
fliC
|
0.0000487 |
1 |
VF0394
|
Motility |
(fliC) flagellin [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
Capsule
|
cps4A
|
0.0001461 |
3 |
VF0144
|
Immune modulation |
(cps4I) capsular polysaccharide biosynthesis protein Cps4I [Capsule (VF0144) - Immune modulation (VFC0258)] [Streptococcus pneumoniae TIGR4]
|
|
Autolysin
|
lytA
|
0.0000974 |
1 |
VF0143
|
Exoenzyme |
(cbpD) choline binding protein D [Autolysin (VF0143) - Exoenzyme (VFC0251)] [Streptococcus pneumoniae TIGR4]
|
|
LPS
|
flmF2
|
1.0002434 |
20,536 |
VF0542
|
Immune modulation |
(flmF2) glycosyl transferase family protein [LPS (VF0542) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
CBPs
|
pce/cbpE
|
0.0000974 |
2 |
VF0145
|
Adherence |
(pce/cbpE) choline binding protein E [CBPs (VF0145) - Adherence (VFC0001)] [Streptococcus pneumoniae TIGR4]
|
|
Neuraminidase
|
nanB
|
0.0000487 |
1 |
VF0148
|
Exoenzyme |
(nanB) neuraminidase B [Neuraminidase (VF0148) - Exoenzyme (VFC0251)] [Streptococcus pneumoniae TIGR4]
|
|
HitABC
|
hitB
|
0.0000487 |
1 |
VF0268
|
Nutritional/Metabolic factor |
(hitB) iron ABC transporter permease [HitABC (VF0268) - Nutritional/Metabolic factor (VFC0272)] [Haemophilus influenzae Rd KW20]
|
|
AdsA
|
adsA
|
0.0000487 |
1 |
VF0422
|
Immune modulation |
(adsA) Adenosine synthase A [AdsA (VF0422) - Immune modulation (VFC0258)] [Staphylococcus aureus subsp. aureus MW2]
|
|
IgA1 protease
|
iga
|
0.0000974 |
2 |
VF0147
|
Immune modulation |
(iga) G5 domain-containing protein [IgA1 protease (VF0147) - Immune modulation (VFC0258)] [Streptococcus pneumoniae TIGR4]
|
|
LPS
|
lpxC
|
0.0000487 |
1 |
VF0466
|
Immune modulation |
(lpxC) UDP-3-O-acyl-N-acetylglucosamine deacetylase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU]
|
|
Auto
|
aut
|
0.0000487 |
1 |
VF0348
|
Invasion |
(aut) autolysin [Auto (VF0348) - Invasion (VFC0083)] [Listeria monocytogenes EGD-e]
|
|
Enterobactin
|
fepE
|
0.0000974 |
2 |
VF0228
|
Nutritional/Metabolic factor |
(fepE) LPS O-antigen length regulator [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073]
|
|
Staphylokinase
|
sak
|
0.0000487 |
1 |
VF0021
|
Exoenzyme |
(sak) Staphylokinase precursor [Staphylokinase (VF0021) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus MW2]
|
|
EF-Tu
|
tufA
|
1.0018501 |
20,539 |
VF0460
|
Adherence |
(tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
SE
|
sec
|
0.0048201 |
98 |
VF0020
|
Exotoxin |
(seb) staphylococcal enterotoxin B [SE (VF0020) - Exotoxin (VFC0235)] [Staphylococcus aureus S6]
|
|
GRAB
|
grab
|
0.8824188 |
16,537 |
VF0254
|
Others |
(grab) protein GRAB (protein G-related alpha 2M-binding protein) [GRAB (VF0254) - Others (VFC0346)] [Streptococcus pyogenes M1 GAS]
|
|
MprAB
|
mprB
|
0.0000487 |
1 |
VF0298
|
Regulation |
(mprB) two component histidine-protein kinase/phosphatase MprB [MprAB (VF0298) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
Gamma-hemolysin
|
hlgC
|
0.0000487 |
1 |
VF0011
|
Exotoxin |
(hlgC) gamma-hemolysin component C [Gamma-hemolysin (VF0011) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Isocitrate lyase
|
icl
|
0.0000487 |
1 |
VF0253
|
Others |
(icl) Isocitrate lyase Icl (isocitrase) (isocitratase) [Isocitrate lyase (VF0253) - Others (VFC0346)] [Mycobacterium tuberculosis H37Rv]
|
|
GAS pili
|
fctB
|
0.642485 |
3,396 |
VF0531
|
Adherence |
(lepA) signal peptidase I [GAS pili (VF0531) - Adherence (VFC0001)] [Streptococcus pyogenes MGAS5005]
|
|
Intercellular adhesion proteins
|
icaA
|
0.0000487 |
1 |
VF0014
|
Biofilm |
(icaA) N-acetylglucosaminyltransferase, involved in polysaccharide intercellular adhesin(PIA) synthesis [Intercellular adhesion proteins (VF0014) - Biofilm (VFC0271)] [Staphylococcus aureus subsp. aureus MW2]
|
|
KatA
|
katA
|
0.0000487 |
1 |
VF0454
|
Stress survival |
(katA) catalase [KatA (VF0454) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
|
|
TcdA
|
toxA
|
0.0000487 |
1 |
VF0376
|
Exotoxin |
(toxA) toxin A [TcdA (VF0376) - Exotoxin (VFC0235)] [Clostridium difficile 630]
|
|
SIC
|
sic
|
0.2008374 |
3,296 |
VF0255
|
Immune modulation |
(sic) inhibitor of complement-mediated lysis [SIC (VF0255) - Immune modulation (VFC0258)] [Streptococcus pyogenes M1 GAS]
|
|
MsrAB
|
msrA/B(pilB
|
1.0101271 |
20,517 |
VF0456
|
Stress survival |
(msrA/B(pilB)) trifunctional thioredoxin/methionine sulfoxide reductase A/B protein [MsrAB (VF0456) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
|
|
Eap/Map
|
eap/map
|
0.0000487 |
1 |
VF0016
|
Adherence |
(eap/map) extracellular adherence protein Eap/Map [Eap/Map (VF0016) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
|
|
SigA
|
sigA/rpoV
|
0.0000487 |
1 |
VF0257
|
Regulation |
(sigA/rpoV) RNA polymerase sigma factor SigA [SigA (VF0257) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
HSI-1
|
hsiB1/vipA/tssB
|
0.0000487 |
1 |
VF0334
|
Effector delivery system |
(hsiB1/vipA/tssB) type VI secretion system tubule-forming protein VipA [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
SCI (Salmonella centrisome island)/SPI-6 T6SS
|
STM0274
|
0.0000487 |
1 |
VF0974
|
Effector delivery system |
|
|
SDr
|
sdrE
|
0.0000974 |
2 |
VF0019
|
Adherence |
(sdrE) Ser-Asp rich fibrinogen-binding bone sialoprotein-binding protein [SDr (VF0019) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Alginate
|
algU
|
0.0000487 |
1 |
VF0091
|
Biofilm |
(algU) alginate biosynthesis protein AlgZ/FimS [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1]
|
|
Urease
|
ureG
|
0.0000487 |
1 |
VF0050
|
Stress survival |
(ureG) urease accessory protein (ureG) [Urease (VF0050) - Stress survival (VFC0282)] [Helicobacter pylori 26695]
|
|
CcmC
|
ccmF
|
0.0000487 |
1 |
VF0292
|
Nutritional/Metabolic factor |
(ccmF) cytochrome c heme lyase subunit CcmF [CcmC (VF0292) - Nutritional/Metabolic factor (VFC0272)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
SLO
|
slo
|
1.0033108 |
20,536 |
VF0250
|
Exotoxin |
(slo) streptolysin O precursor [SLO (VF0250) - Exotoxin (VFC0235)] [Streptococcus pyogenes M1 GAS]
|
|
FnBPs
|
fnbB
|
0.0000487 |
1 |
VF0010
|
Adherence |
(fnbB) fibronectin-binding protein B [FnBPs (VF0010) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Mitogenic factor
|
mf/spd
|
1.9957155 |
20,536 |
VF0252
|
Exoenzyme |
(mf/spd) deoxyribonuclease [Mitogenic factor (VF0252) - Exoenzyme (VFC0251)] [Streptococcus pyogenes M1 GAS]
|
|
SLS
|
sagA
|
0.9996105 |
20,511 |
VF0251
|
Exotoxin |
(sagA) streptolysin S associated protein [SLS (VF0251) - Exotoxin (VFC0235)] [Streptococcus pyogenes M1 GAS]
|