Research Article Details

Article ID: A00127
PMID: 35212996
Source: Methods Mol Biol
Title: Computational Pipeline for Next-Generation Sequencing (NGS) Studies in Genetics of NASH.
Abstract: High-throughput sequencing (HTS) technologies have contributed to expand current knowledge of the biology of complex diseases, including nonalcoholic fatty liver disease (NAFLD). Genome-wide association studies, whole exome sequencing, and sequencing of entire genes are used to identify variants and/or mutations that predispose to the disease pathogenesis. Here, we present a tutorial that may guide readers to manage high volume of genetics data in the context of Next-Generation Sequencing (NGS) studies.
DOI: 10.1007/978-1-0716-2128-8_16