Repositioning Candidates
Repositioning candidates for NAFLD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and NAFLD-associated disease in NAFLDkb are presented with knowledge graphs.
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1608 records.
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| R0001 | DB00002 | approved | biotech | Cetuximab | Therapeutic strategy associated | Details |
| R0002 | DB00003 | approved | biotech | Dornase alfa | Therapeutic strategy associated | Details |
| R0003 | DB00005 | approved; investigational | biotech | Etanercept | Therapeutic strategy associated | Details |
| R0004 | DB00009 | approved | biotech | Alteplase | Indication associated | Details |
| R0005 | DB00015 | approved; investigational | biotech | Reteplase | Indication associated | Details |
| R0006 | DB00016 | approved | biotech | Erythropoietin | Therapeutic strategy associated | Details |
| R0007 | DB00017 | approved; investigational | biotech | Salmon calcitonin | Indication associated | Details |
| R0008 | DB00022 | approved | biotech | Peginterferon alfa-2b | Therapeutic strategy associated | Details |
| R0009 | DB00026 | approved | biotech | Anakinra | Therapeutic strategy associated | Details |
| R0010 | DB00028 | approved; investigational | biotech | Human immunoglobulin G | Indication associated | Details |
| R0011 | DB00029 | approved | biotech | Anistreplase | Indication associated | Details |
| R0012 | DB00031 | approved | biotech | Tenecteplase | Indication associated | Details |
| R0013 | DB00035 | approved | small molecule | Desmopressin | Indication associated | Details |
| R0014 | DB00043 | approved; investigational | biotech | Omalizumab | Therapeutic strategy associated | Details |
| R0015 | DB00046 | approved | biotech | Insulin lispro | Indication associated | Details |
| R0016 | DB00049 | approved; investigational | biotech | Rasburicase | Indication associated | Details |
| R0017 | DB00051 | approved; experimental | biotech | Adalimumab | Therapeutic strategy associated | Details |
| R0018 | DB00054 | approved | biotech | Abciximab | Therapeutic strategy associated | Details |
| R0019 | DB00063 | approved; investigational | biotech | Eptifibatide | Therapeutic strategy associated | Details |
| R0020 | DB00065 | approved | biotech | Infliximab | Therapeutic strategy associated | Details |
| R0021 | DB00071 | approved | biotech | Insulin pork | Indication associated | Details |
| R0022 | DB00073 | approved | biotech | Rituximab | Therapeutic strategy associated | Details |
| R0023 | DB00080 | approved; investigational | small molecule | Daptomycin | Indication associated | Details |
| R0024 | DB00081 | approved; investigational | biotech | Tositumomab | Therapeutic strategy associated | Details |
| R0025 | DB00083 | approved; investigational | biotech | Botulinum toxin type A | Indication associated | Details |
| R0026 | DB00086 | approved; investigational | biotech | Streptokinase | Indication associated | Details |
| R0027 | DB00091 | approved; investigational; vet_approved | small molecule | Cyclosporine | Therapeutic strategy associated | Details |
| R0028 | DB00098 | approved | biotech | Antithymocyte immunoglobulin (rabbit) | Therapeutic strategy associated | Details |
| R0029 | DB00102 | approved; investigational | biotech | Becaplermin | Indication associated | Details |
| R0030 | DB00107 | approved; vet_approved | biotech | Oxytocin | Indication associated | Details |
| R0031 | DB00108 | approved; investigational | biotech | Natalizumab | Therapeutic strategy associated | Details |
| R0032 | DB00114 | approved; investigational; nutraceutical | small molecule | Pyridoxal phosphate | Indication associated | Details |
| R0033 | DB00116 | nutraceutical | small molecule | Tetrahydrofolic acid | Indication associated | Details |
| R0034 | DB00117 | investigational; nutraceutical | small molecule | Histidine | Therapeutic strategy associated | Details |
| R0035 | DB00119 | approved; investigational; nutraceutical | small molecule | Pyruvic acid | Indication associated | Details |
| R0036 | DB00120 | approved; investigational; nutraceutical | small molecule | Phenylalanine | Indication associated | Details |
| R0037 | DB00121 | approved; investigational; nutraceutical | small molecule | Biotin | Target associated | Details |
| R0038 | DB00125 | investigational; nutraceutical | small molecule | Arginine | Therapeutic strategy associated | Details |
| R0039 | DB00127 | experimental; nutraceutical | small molecule | Spermine | Indication associated | Details |
| R0040 | DB00129 | approved; nutraceutical | small molecule | Ornithine | Indication associated | Details |
| R0041 | DB00130 | approved; investigational; nutraceutical | small molecule | L-Glutamine | Therapeutic strategy associated | Details |
| R0042 | DB00131 | approved; investigational; nutraceutical | small molecule | Adenosine phosphate | Target associated | Details |
| R0043 | DB00132 | approved; investigational; nutraceutical | small molecule | alpha-Linolenic acid | Therapeutic strategy associated | Details |
| R0044 | DB00134 | approved; nutraceutical | small molecule | Methionine | Therapeutic strategy associated | Details |
| R0045 | DB00137 | approved; investigational; nutraceutical | small molecule | Lutein | Therapeutic strategy associated | Details |
| R0046 | DB00138 | approved; nutraceutical | small molecule | Cystine | Therapeutic strategy associated | Details |
| R0047 | DB00139 | approved; nutraceutical | small molecule | Succinic acid | Indication associated | Details |
| R0048 | DB00141 | approved; investigational; nutraceutical | small molecule | N-Acetylglucosamine | Indication associated | Details |
| R0049 | DB00146 | approved; nutraceutical | small molecule | Calcifediol | Indication associated | Details |
| R0050 | DB00147 | experimental; nutraceutical | small molecule | Pyridoxal | Indication associated | Details |
| R0051 | DB00148 | approved; investigational; nutraceutical | small molecule | Creatine | Indication associated | Details |
| R0052 | DB00150 | approved; nutraceutical; withdrawn | small molecule | Tryptophan | Indication associated | Details |
| R0053 | DB00152 | approved; investigational; nutraceutical; vet_approved | small molecule | Thiamine | Therapeutic strategy associated | Details |
| R0054 | DB00154 | investigational; nutraceutical | small molecule | Dihomo-gamma-linolenic acid | Therapeutic strategy associated | Details |
| R0055 | DB00157 | approved; nutraceutical | small molecule | NADH | Target associated | Details |
| R0056 | DB00159 | approved; nutraceutical | small molecule | Icosapent | Therapeutic strategy associated | Details |
| R0057 | DB00169 | approved; nutraceutical | small molecule | Cholecalciferol | Therapeutic strategy associated | Details |
| R0058 | DB00170 | approved; nutraceutical | small molecule | Menadione | Therapeutic strategy associated | Details |
| R0059 | DB00171 | investigational; nutraceutical | small molecule | ATP | Indication associated | Details |
| R0060 | DB00173 | approved; nutraceutical | small molecule | Adenine | Target associated | Details |
| R0061 | DB00174 | approved; investigational; nutraceutical | small molecule | Asparagine | Indication associated | Details |
| R0062 | DB00175 | approved | small molecule | Pravastatin | Target associated | Details |
| R0063 | DB00176 | approved; investigational | small molecule | Fluvoxamine | Indication associated | Details |
| R0064 | DB00177 | approved; investigational | small molecule | Valsartan | Therapeutic strategy associated | Details |
| R0065 | DB00178 | approved | small molecule | Ramipril | Therapeutic strategy associated | Details |
| R0066 | DB00180 | approved; investigational | small molecule | Flunisolide | Therapeutic strategy associated | Details |
| R0067 | DB00181 | approved | small molecule | Baclofen | Therapeutic strategy associated | Details |
| R0068 | DB00182 | approved; illicit; investigational | small molecule | Amphetamine | Indication associated | Details |
| R0069 | DB00187 | approved | small molecule | Esmolol | Indication associated | Details |
| R0070 | DB00188 | approved; investigational | small molecule | Bortezomib | Therapeutic strategy associated | Details |
| R0071 | DB00193 | approved; investigational | small molecule | Tramadol | Therapeutic strategy associated | Details |
| R0072 | DB00195 | approved; investigational | small molecule | Betaxolol | Indication associated | Details |
| R0073 | DB00199 | approved; investigational; vet_approved | small molecule | Erythromycin | Indication associated | Details |
| R0074 | DB00201 | approved | small molecule | Caffeine | Indication associated | Details |
| R0075 | DB00203 | approved; investigational | small molecule | Sildenafil | Indication associated | Details |
| R0076 | DB00204 | approved; investigational | small molecule | Dofetilide | Indication associated | Details |
| R0077 | DB00206 | approved; investigational | small molecule | Reserpine | Therapeutic strategy associated | Details |
| R0078 | DB00208 | approved | small molecule | Ticlopidine | Therapeutic strategy associated | Details |
| R0079 | DB00210 | approved | small molecule | Adapalene | Therapeutic strategy associated | Details |
| R0080 | DB00212 | experimental | small molecule | Remikiren | Indication associated | Details |
| R0081 | DB00214 | approved | small molecule | Torasemide | Therapeutic strategy associated | Details |
| R0082 | DB00215 | approved | small molecule | Citalopram | Indication associated | Details |
| R0083 | DB00216 | approved; investigational | small molecule | Eletriptan | Therapeutic strategy associated | Details |
| R0084 | DB00217 | approved | small molecule | Bethanidine | Therapeutic strategy associated | Details |
| R0085 | DB00218 | approved; investigational | small molecule | Moxifloxacin | Indication associated | Details |
| R0086 | DB00223 | approved | small molecule | Diflorasone | Therapeutic strategy associated | Details |
| R0087 | DB00226 | approved | small molecule | Guanadrel | Indication associated | Details |
| R0088 | DB00227 | approved; investigational | small molecule | Lovastatin | Therapeutic strategy associated | Details |
| R0089 | DB00230 | approved; investigational | small molecule | Pregabalin | Indication associated | Details |
| R0090 | DB00232 | withdrawn | small molecule | Methyclothiazide | Therapeutic strategy associated | Details |
| R0091 | DB00234 | approved; experimental | small molecule | Reboxetine | Indication associated | Details |
| R0092 | DB00240 | approved | small molecule | Alclometasone | Therapeutic strategy associated | Details |
| R0093 | DB00244 | approved | small molecule | Mesalazine | Therapeutic strategy associated | Details |
| R0094 | DB00250 | approved; investigational | small molecule | Dapsone | Therapeutic strategy associated | Details |
| R0095 | DB00253 | approved | small molecule | Medrysone | Therapeutic strategy associated | Details |
| R0096 | DB00261 | approved | small molecule | Anagrelide | Therapeutic strategy associated | Details |
| R0097 | DB00263 | approved; vet_approved | small molecule | Sulfisoxazole | Indication associated | Details |
| R0098 | DB00264 | approved; investigational | small molecule | Metoprolol | Therapeutic strategy associated | Details |
| R0099 | DB00270 | approved; investigational | small molecule | Isradipine | Indication associated | Details |
| R0100 | DB00277 | approved | small molecule | Theophylline | Therapeutic strategy associated | Details |