Associated Diseases

NAFLD-associated diseases and detailed information are manually extracted from research articles and Disease Ontology. For each associated disease, reference researches are provided, and related drugs and repositioning candidates in NAFLDkb are presented with knowledge graphs.

17 records.
Diseases ID DO ID Disease Name Definition Class
I01 552 Pneumonia A lung disease that involves lung parenchyma or alveolar inflammation and abnormal alveolar filling with fluid (consolidation and exudation). It results from a variety of causes including infection with bacteria, viruses, fungi or parasites, and chemical or physical injury to the lungs. It is accompanied by fever, chills, cough, and difficulty in breathing. http://en.wikipedia.org/wiki/Pneumonia disease of anatomical entity/respiratory system disease/ lower respiratory tract disease/lung disease Details
I02 5113 Nutritional deficiency disease A nutrition disease that is characterized by deficiency of a nutritional element, such as a vitamin, mineral, carbohydrate, protein, fat, or general energy content. https://medlineplus.gov/malnutrition.html disease of metabolism/acquired metabolic disease/nutrition disease Details
I03 10211 Cholelithiasis cholelithiasis disease of anatomical entity/gastrointestinal system disease/gallbladder disease Details
I04 1459 Hypothyroidism A thyroid gland disease which involves an underproduction of thyroid hormone. https://medlineplus.gov/hypothyroidism.html disease of anatomical entity/ endocrine system disease/ thyroid gland disease Details
I05 9352 Type 2 diabetes mellitus A diabetes that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both. A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. http://en.wikipedia.org/wiki/Diabetes, http://en.wikipedia.org/wiki/Diabetes_mellitus_type_2 disease of metabolism/inherited metabolic disorder/ carbohydrate metabolic disorder/glucose metabolism disease/diabetes/ diabetes mellitus Details
I06 811 Lipodystrophy A connective tissue disease that is characterized by marked reduction, absence, and/or the redistribution of adipose tissue. https://www.ncbi.nlm.nih.gov/pubmed/25690482, https://www.ncbi.nlm.nih.gov/pubmed/25833179 disease of anatomical entity/ musculoskeletal system disease/ connective tissue disease Details
I07 1936 Arteriosclerosis Build-up of fatty material and calcium deposition in the arterial wall resulting in partial or complete occlusion of the arterial lumen.https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=ncit&code=C35768 disease of anatomical entity/cardiovascular system disease/ vascular disease/ artery disease Details
I08 114 Cardiovascular system disease A disease of anatomical entity which occurs in the blood, heart, blood vessels or the lymphatic system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells or lymph to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis. http://en.wikipedia.org/wiki/Circulatory_system disease of anatomical entity Details
I09 104 Bacterial infectious disease A disease by infectious agent that results_in infection, has_material_basis_in Bacteria. http://en.wikipedia.org/wiki/Pathogenic_bacteria disease by infectious agent Details
I10 2987 Familial Mediterranean fever An autoimmune disease characterized by recurrent episodes of fever and acute inflammation of the membranes lining the abdomen, joints and lungs; that has_material_basis_in mutations in the MEFV gene, which encodes the protein pyrin. http://en.wikipedia.org/wiki/Familial_Mediterranean_fever, https://www.rarediseases.org/rare-disease-information/rare-diseases/byID/127/viewAbstract disease of anatomical entity/ immune system disease/primary immunodeficiency disease/primary immunodeficiency disease Details