CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of NAFLD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
stats1
stats2
34330 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C00004 | BRD-A00077618 | 8-bromo-cGMP | PRKG1 | PKA activator | -- | Details |
| C00005 | BRD-A00100033 | nifurtimox | -- | -- | -- | Details |
| C00006 | BRD-A00147595 | balaglitazone | PPARG | Insulin sensitizer; PPAR receptor partial agonist | -- | Details |
| C00007 | BRD-A00150179 | BRD-A00150179 | -- | -- | 5-hydroxytryptophan | Details |
| C00008 | BRD-A00218260 | flutrimazole | -- | -- | -- | Details |
| C00009 | BRD-A00267231 | hemado | ADORA3 | Adenosine receptor agonist | -- | Details |
| C00010 | BRD-A00327403 | BRD-A00327403 | -- | -- | -- | Details |
| C00011 | BRD-A00376169 | KBG | MME | Neprilysin inhibitor | kbg | Details |
| C00012 | BRD-A00420644 | SA-3676 | -- | -- | -- | Details |
| C00013 | BRD-A00474148 | BRD-A00474148 | -- | -- | -- | Details |
| C00014 | BRD-A00520476 | otenzepad | CHRM1; CHRM2 | Acetylcholine receptor antagonist | -- | Details |
| C00015 | BRD-A00522887 | BRD-A00522887 | -- | -- | -- | Details |
| C00016 | BRD-A00546892 | biperiden | CHRM1 | Acetylcholine receptor antagonist | -- | Details |
| C00017 | BRD-A00578795 | zaltoprofen | -- | -- | -- | Details |
| C00018 | BRD-A00626522 | BRD-A00626522 | -- | -- | -- | Details |
| C00019 | BRD-A00680357 | BRD-A00680357 | -- | -- | -- | Details |
| C00020 | BRD-A00758722 | noretynodrel | PGR | Progestogen hormone | -- | Details |
| C00021 | BRD-A00763758 | BRD-A00763758 | -- | -- | -- | Details |
| C00022 | BRD-A00776891 | BRD-A00776891 | -- | -- | -- | Details |
| C00023 | BRD-A00827783 | dyphylline | PDE4A; PDE4B; PDE4C; PDE4D | Adenosine receptor antagonist; Phosphodiesterase inhibitor | -- | Details |
| C00024 | BRD-A00881124 | BRD-A00881124 | -- | -- | -- | Details |
| C00025 | BRD-A00938334 | drospirenone | NR3C2; PGR | Mineralocorticoid receptor antagonist | -- | Details |
| C00026 | BRD-A00993607 | alprenolol | ADRB1; ADRB2 | Adrenergic receptor antagonist | -- | Details |
| C00027 | BRD-A01078468 | hexestrol | ESR1 | Estrogen receptor agonist | -- | Details |
| C00028 | BRD-A01145011 | zebularine | DNMT1; CDA | DNA methyltransferase inhibitor | -- | Details |
| C00029 | BRD-A01295252 | BRD-A01295252 | -- | -- | 7-hydroxy-PIPAT | Details |
| C00030 | BRD-A01317026 | BRD-A01317026 | -- | -- | 7,8-dihydro-L-biopterin | Details |
| C00031 | BRD-A01320529 | salmeterol | ADRB2 | Adrenergic receptor agonist | -- | Details |
| C00032 | BRD-A01346607 | flumetasone | NR3C1 | Glucocorticoid receptor agonist | -- | Details |
| C00033 | BRD-A01403444 | BRD-A01403444 | -- | -- | -- | Details |
| C00034 | BRD-A01434304 | BRD-A01434304 | -- | -- | -- | Details |
| C00035 | BRD-A01493904 | WB-4101 | ADRA1D; ADRA1B; ADRA1A; ADRA2A; ADRA2B; ADRA2C | Adrenergic receptor antagonist | -- | Details |
| C00036 | BRD-A01528713 | BRD-A01528713 | -- | -- | -- | Details |
| C00037 | BRD-A01563671 | cleviprex | CACNA1C; CACNA1D; CACNA1F; CACNA1S | Calcium channel blocker | -- | Details |
| C00038 | BRD-A01593789 | BRD-A01593789 | -- | -- | chlormadinone-acetate | Details |
| C00039 | BRD-A01636364 | bupivacaine | -- | -- | -- | Details |
| C00040 | BRD-A01643550 | prednisolone-acetate | NR3C1 | Glucocorticoid receptor agonist | -- | Details |
| C00041 | BRD-A01645196 | garcinol | -- | -- | -- | Details |
| C00042 | BRD-A01717111 | BRD-A01717111 | -- | -- | -- | Details |
| C00043 | BRD-A01717918 | BRD-A01717918 | -- | -- | -- | Details |
| C00044 | BRD-A01759464 | BRD-A01759464 | -- | -- | -- | Details |
| C00045 | BRD-A01787639 | naftopidil | -- | -- | -- | Details |
| C00046 | BRD-A01826957 | xanthinol | -- | -- | -- | Details |
| C00047 | BRD-A01848933 | BRD-A01848933 | -- | -- | -- | Details |
| C00048 | BRD-A01907367 | FK-33-824 | OPRM1 | Opioid receptor agonist | -- | Details |
| C00049 | BRD-A01960364 | BRD-A01960364 | -- | -- | -- | Details |
| C00050 | BRD-A01973626 | BRD-A01973626 | -- | -- | -- | Details |
| C00051 | BRD-A01976766 | malathion | -- | -- | -- | Details |
| C00052 | BRD-A01999384 | BRD-A01999384 | -- | -- | -- | Details |
| C00053 | BRD-A02006392 | nitrendipine | CACNA1C; CACNA1D; CACNA2D1 | Calcium channel blocker | -- | Details |
| C00054 | BRD-A02176148 | tubaic-acid | -- | -- | -- | Details |
| C00055 | BRD-A02180903 | betamethasone | NR3C1 | Glucocorticoid receptor agonist | -- | Details |
| C00056 | BRD-A02189320 | met-leu-phe | -- | -- | -- | Details |
| C00057 | BRD-A02198599 | EMF-sumo1-9 | -- | -- | -- | Details |
| C00058 | BRD-A02214146 | BRD-A02214146 | -- | -- | -- | Details |
| C00059 | BRD-A02241946 | BRD-A02241946 | -- | -- | -- | Details |
| C00060 | BRD-A02288691 | BRD-A02288691 | -- | -- | -- | Details |
| C00061 | BRD-A02303741 | BRD-A02303741 | -- | -- | EPZ-004777-ANALOG | Details |
| C00062 | BRD-A02333338 | cyclopamine | SMO | Smoothened receptor antagonist | -- | Details |
| C00063 | BRD-A02367930 | BRD-A02367930 | -- | -- | ethinyl-estradiol | Details |
| C00064 | BRD-A02481876 | importazole | KPNB1 | Importin-beta transport receptor inhibitor | -- | Details |
| C00065 | BRD-A02501536 | BRD-A02501536 | -- | -- | -- | Details |
| C00066 | BRD-A02508087 | NMDA | GRIN1; GRIN2A; GRIN2B | Glutamate receptor agonist | -- | Details |
| C00067 | BRD-A02579693 | etoposide | TOP2A; TOP2B | Topoisomerase inhibitor | -- | Details |
| C00068 | BRD-A02612852 | BRD-A02612852 | -- | -- | -- | Details |
| C00069 | BRD-A02710418 | meptazinol | -- | -- | -- | Details |
| C00070 | BRD-A02713983 | dihydrodeoxygedunin | NTRK2 | Growth factor receptor activator | -- | Details |
| C00071 | BRD-A02726762 | BRD-A02726762 | -- | -- | -- | Details |
| C00072 | BRD-A02743701 | cilnidipine | CACNA1B | Calcium channel blocker | -- | Details |
| C00073 | BRD-A02747686 | BRD-A02747686 | -- | -- | -- | Details |
| C00074 | BRD-A02759312 | betaxolol | ADRB1; ADRB2 | Adrenergic receptor antagonist | -- | Details |
| C00075 | BRD-A02799884 | BRD-A02799884 | -- | -- | -- | Details |
| C00076 | BRD-A02809788 | ARG-TC-41 | -- | -- | -- | Details |
| C00077 | BRD-A02836799 | BRD-A02836799 | -- | -- | -- | Details |
| C00078 | BRD-A02904414 | SR8278 | -- | -- | SR-8278 | Details |
| C00079 | BRD-A02927672 | BRD-A02927672 | -- | -- | -- | Details |
| C00080 | BRD-A02990301 | lofexidine | ADRA2A | Adrenergic receptor agonist | -- | Details |
| C00081 | BRD-A03044413 | micropenin | -- | -- | -- | Details |
| C00082 | BRD-A03061970 | alizapride | DRD2 | Dopamine receptor antagonist | -- | Details |
| C00083 | BRD-A03121430 | BRD-A03121430 | -- | -- | -- | Details |
| C00084 | BRD-A03182941 | BRD-A03182941 | -- | -- | -- | Details |
| C00085 | BRD-A03216249 | mepivacaine | -- | -- | -- | Details |
| C00086 | BRD-A03248660 | BRD-A03248660 | -- | -- | -- | Details |
| C00087 | BRD-A03249105 | ICI-182780 | ESR1 | Estrogen receptor antagonist | -- | Details |
| C00088 | BRD-A03323675 | ritonavir | CYP1A2; CYP3A7; CYP2B6; CYP2C19; CYP2C8; CYP2C9; CYP2D6; CYP2E1; CYP3A4; CYP3A5 | HIV protease inhibitor | -- | Details |
| C00089 | BRD-A03359064 | ICI-89406 | ADRB1; ADRB2 | Adrenergic receptor antagonist | -- | Details |
| C00090 | BRD-A03427350 | sulindac | AKR1B1; PTGS1; PTGS2 | Cyclooxygenase inhibitor | -- | Details |
| C00091 | BRD-A03436432 | BRD-A03436432 | -- | -- | -- | Details |
| C00092 | BRD-A03506276 | XL-888 | -- | -- | -- | Details |
| C00093 | BRD-A03520402 | ST-014366 | -- | -- | -- | Details |
| C00094 | BRD-A03623303 | metoprolol | ADRB1; ADRB2 | Adrenergic receptor antagonist | -- | Details |
| C00095 | BRD-A03668899 | BRD-A03668899 | -- | -- | -- | Details |
| C00096 | BRD-A03684405 | BRD-A03684405 | -- | -- | -- | Details |
| C00097 | BRD-A03764094 | BRD-A03764094 | -- | -- | -- | Details |
| C00098 | BRD-A03772856 | BRD-A03772856 | -- | -- | -- | Details |
| C00099 | BRD-A03816571 | CP-55940 | CNR1; CNR2; GPR55 | Cannabinoid receptor agonist | -- | Details |
| C00100 | BRD-A03898562 | BRD-A03898562 | -- | -- | -- | Details |
| C00101 | BRD-A03926027 | ST-014147 | -- | -- | -- | Details |
| C00102 | BRD-A03932035 | methscopolamine | CHRM1; CHRM2; CHRM3 | Acetylcholine receptor antagonist | -- | Details |
| C00103 | BRD-A03940741 | BRD-A03940741 | -- | -- | -- | Details |