Research Article Details
Article ID: | A13481 |
PMID: | 29956202 |
Source: | Adv Exp Med Biol |
Title: | Introduction. |
Abstract: | Obesity is fast becoming a major disorder for mankind. Numerous lifestyle factors play a role in the rising obesity epidemic, including changes in the diet and the lack of physical activity. Unfortunately, more than two-thirds of the adult population in developed countries is considered overweight and more than a third of them are obese. In addition to the well-publicized association of obesity with type II diabetes and cardiovascular diseases, emerging evidence indicates that obesity represents a major risk factor for fatty liver diseases and fatty liver disease-associated hepatocellular carcinoma (HCC). |
DOI: | 10.1007/978-981-10-8684-7_1 |

Strategy ID | Therapy Strategy | Synonyms | Therapy Targets | Therapy Drugs |
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Diseases ID | DO ID | Disease Name | Definition | Class | |
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I05 | 9352 | Type 2 diabetes mellitus | A diabetes that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both. A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. http://en.wikipedia.org/wiki/Diabetes, http://en.wikipedia.org/wiki/Diabetes_mellitus_type_2 | disease of metabolism/inherited metabolic disorder/ carbohydrate metabolic disorder/glucose metabolism disease/diabetes/ diabetes mellitus | Details |
I14 | 9970 | Obesity | An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness. https://en.wikipedia.org/wiki/Obesity | disease of metabolism/acquired metabolic disease/ nutrition disease/overnutrition | Details |