Research Article Details
| Article ID: | A17938 |
| PMID: | 27465954 |
| Source: | Zhonghua Gan Zang Bing Za Zhi |
| Title: | [Research advances in the impact of nonalcoholic fatty liver disease on cardiac structure and function]. |
| Abstract: | Nonalcoholic fatty liver disease (NAFLD) has become the most common chronic liver disease in developed and developing countries. NAFLD is considered to be the manifestation of metabolic syndrome in the liver and an important risk factor for cardiovascular diseases as well. Studies have shown that NAFLD patients have significantly increased the prevalence rates of the diseases including ischemic heart disease and heart failure. Therefore, whether the changes in cardiac structure and impaired cardiac function occur before the development of organic heart diseases in NAFLD patients has attracted scholars' attention. With reference to the published literature, this article reviews the research advances in the association between NAFLD and cardiac changes in adults, children, and patients with diabetes and hypertension. |
| DOI: | 10.3760/cma.j.issn.1007-3418.2016.06.015 |
| Strategy ID | Therapy Strategy | Synonyms | Therapy Targets | Therapy Drugs |
|---|
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
|---|
| Diseases ID | DO ID | Disease Name | Definition | Class | |
|---|---|---|---|---|---|
| I12 | 10763 | Hypertension | An artery disease characterized by chronic elevated blood pressure in the arteries. https://en.wikipedia.org/wiki/Hypertension, https://www.ncbi.nlm.nih.gov/pubmed/24352797 | disease of anatomical entity/ cardiovascular system disease/vascular disease/ artery disease | Details |
| I05 | 9352 | Type 2 diabetes mellitus | A diabetes that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both. A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. http://en.wikipedia.org/wiki/Diabetes, http://en.wikipedia.org/wiki/Diabetes_mellitus_type_2 | disease of metabolism/inherited metabolic disorder/ carbohydrate metabolic disorder/glucose metabolism disease/diabetes/ diabetes mellitus | Details |