Research Article Details

Article ID: A18489
PMID: 27096315
Source: Immunity
Title: Getting the Skinny on CD4(+) T Cell Survival in Fatty Livers.
Abstract: Non-alcoholic fatty liver disease is associated with hepatocellular carcinoma. In the March 10 issue of Nature, Greten and colleagues report that this metabolic disruption affects tumor surveillance by depleting CD4+ T helper cells through lipotoxic mechanisms associated with NAFLD.
DOI: 10.1016/j.immuni.2016.04.001