Research Article Details
| Article ID: | A22260 |
| PMID: | 24709815 |
| Source: | Nat Rev Gastroenterol Hepatol |
| Title: | NASH: the tribulations of conducting NASH trials. |
| Abstract: | Designing clinical trials for the treatment of NASH is challenging. The pathogenesis of this disease is poorly understood and is probably multifactorial. A trial of a phosphodiesterase-4 inhibitor produced negative results, despite promising preclinical data. Examining why this trial failed might help us design better trials of treatments for NASH in the future. |
| DOI: | 10.1038/nrgastro.2014.51 |
| Strategy ID | Therapy Strategy | Synonyms | Therapy Targets | Therapy Drugs |
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| Diseases ID | DO ID | Disease Name | Definition | Class |
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| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress |
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