Research Article Details
Article ID: | A22686 |
PMID: | 25951695 |
Source: | Przegl Lek |
Title: | [Determinants of nonalcoholic fatty liver disease in men and women with type 2 diabetes]. |
Abstract: | Nonalcoholic fatty liver disease (NAFLD) is recognized in 20-30% of general population but among the people with impaired glucose metabolism this percentage is about 70-90%. The aim of this study is to assess the determinants of NAFLD with respect to patients' gender. We examined 180 patients, 73 women and 107 men. Increased body mass index (BMI), waist circumference above the norm are the determinants of NAFLD irrespectively to gender. Besides it has been observed that in the women group the increase of HDL-cholesterol by 1 mmol/l decreases the chances of NAFLD occurrence by 90%. |
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Strategy ID | Therapy Strategy | Synonyms | Therapy Targets | Therapy Drugs |
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Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
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Diseases ID | DO ID | Disease Name | Definition | Class | |
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I05 | 9352 | Type 2 diabetes mellitus | A diabetes that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both. A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. http://en.wikipedia.org/wiki/Diabetes, http://en.wikipedia.org/wiki/Diabetes_mellitus_type_2 | disease of metabolism/inherited metabolic disorder/ carbohydrate metabolic disorder/glucose metabolism disease/diabetes/ diabetes mellitus | Details |