Research Article Details

Article ID: A35746
PMID: 19783958
Source: Molecules
Title: Heterocyclic analogs of thioflavones: synthesis and NMR spectroscopic investigations.
Abstract: The synthesis of several hitherto unknown heterocyclic ring systems derived from thioflavone is described. Coupling of various o-haloheteroarenecarbonyl chlorides with phenylacetylene gives 1-(o-haloheteroaryl)-3-phenylprop-2-yn-1-ones, which were treated with NaSH in refluxing ethanol to yield the corresponding bi- and tricyclic annelated 2-phenylthiopyran-4-ones. Detailed NMR spectroscopic investigations of the ring systems and their precursors are presented.
DOI: 10.3390/molecules14093814