Research Article Details
| Article ID: | A35746 |
| PMID: | 19783958 |
| Source: | Molecules |
| Title: | Heterocyclic analogs of thioflavones: synthesis and NMR spectroscopic investigations. |
| Abstract: | The synthesis of several hitherto unknown heterocyclic ring systems derived from thioflavone is described. Coupling of various o-haloheteroarenecarbonyl chlorides with phenylacetylene gives 1-(o-haloheteroaryl)-3-phenylprop-2-yn-1-ones, which were treated with NaSH in refluxing ethanol to yield the corresponding bi- and tricyclic annelated 2-phenylthiopyran-4-ones. Detailed NMR spectroscopic investigations of the ring systems and their precursors are presented. |
| DOI: | 10.3390/molecules14093814 |

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