Research Article Details
| Article ID: | A47528 |
| PMID: | 21927138 |
| Source: | Indian J Psychiatry |
| Title: | Alcoholic liver disease in a psychiatric hospital. |
| Abstract: | Liver biopsy was analysed for 41 alcoholics, satisfying RDC criteria. Alcoholic liver disease was diagnosed as per the guidelines from the WHO/ICMR Workshop. For the entire group mean consumption of alcohol was 183.lg. of ethanol for an average of 9.7 years. Only 5 persons (12.2%) had normal liver. Six persons (14.6%) had Fatty liver, 23 (56.1%) had alcoholic hepatitis, and 4(9.7%) had precirrhosis and cirrhosis. Biochemical analysis showed that alcoholics had elevated values of SGOT, SGPT and GGT as compared to control non - drinker population. Malnutrition did not appear to be a contaminating factor for the observed histopathological findings. |
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| Strategy ID | Therapy Strategy | Synonyms | Therapy Targets | Therapy Drugs |
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| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
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| Diseases ID | DO ID | Disease Name | Definition | Class |
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| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress | |
|---|---|---|---|---|---|---|---|
| D328 | Serine | Chemical drug | DB00133 | SRR | Improve insulin resistance | Under clinical trials | Details |
| D545 | Pig placenta extract | Biological extract | -- | -- | -- | Under clinical trials | Details |
| D094 | Cysteamine | Chemical drug | DB00847 | GSS stimulant | Renal drug | Under clinical trials | Details |
| D095 | Cysteamine bitartrate | Chemical drug | DB00847 | -- | -- | Under clinical trials | Details |