Research Article Details

Article ID: A47948
PMID: 28542140
Source: Cell Death Dis
Title: miR-21 ablation and obeticholic acid ameliorate nonalcoholic steatohepatitis in mice.
Abstract: This corrects the article DOI: 10.1038/cddis.2017.172.
DOI: 10.1038/cddis.2017.246

Strategy ID Therapy Strategy Synonyms Therapy Targets Therapy Drugs

Target ID Target Name GENE Action Class UniProtKB ID Entry Name
T10 Caspase-1 CASP1 inhibitor Enzyme P29466 CASP1_HUMAN Details

Diseases ID DO ID Disease Name Definition Class

Drug ID Drug Name Type DrugBank ID Targets Category Latest Progress
D248 Obeticholic Acid Chemical drug DB05990 NR1H4 activator; NR1H4 agonist; FXR agonist Enhance lipid metabolism Approval rejected Details