Abstract: | This review summarizes the highlights in hepatopathology presented during the Prague Hepatology Meeting 2010. Gut flora (microbiome) and intestinal permeability seems to play an important role during progression into liver cirrhosis in patients with non-alcoholic steatohepatitis. Molecular diagnosis allows the distinction of several types of hepatocellular adenoma with different risks of malignant progression. Experimental hepatology is currently focused on the role of epigenetics during pathogenesis of alcoholic liver disease. The most studied topic in viral hepatitis C is the mechanisms of resistance to antiviral treatment. Pathogenesis of liver fibrosis and the role of keratins in the pathology of liver disease are areas of scientific interest as well. |