Research Article Details
| Article ID: | A06103 |
| PMID: | 33007261 |
| Source: | Cell |
| Title: | One Ring to Rule Them All: Mitochondrial Circular RNAs Control Mitochondrial Function. |
| Abstract: | Circular RNAs (circRNAs) have emerged as key regulators of a wide variety of biological processes, but the roles of mitochondrial circRNAs are largely unknown. In this issue of Cell, Zhao et al. (2020) reveal that mitochondrial DNA-encoded circRNAs interact with ATP synthase subunit β (ATP5B) to inhibit the output of mitochondrial reactive oxygen species and the activation of liver fibroblasts, which regulate the pathogenesis of liver disease. |
| DOI: | 10.1016/j.cell.2020.09.028 |
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