Research Article Details

Article ID: A06298
PMID: 32937148
Source: Immunity
Title: Two Roads Diverge in the Sick Liver, Monocytes Travel Both.
Abstract: Liver macrophages play critical roles in the pathogenesis of non-alcoholic steatohepatitis (NASH). In this issue of Immunity, Tran et al. and Remmerie et al. reveal that Ly6Chi monocytes in NASH replace dying resident Kupffer cells, while concomitantly are differentiating into distinct lipid associated macrophages.
DOI: 10.1016/j.immuni.2020.08.006