Research Article Details

Article ID: A06452
PMID: 32877688
Source: Cell Metab
Title: Not Chopped Liver-A Careful, Fate-Mapping Study of Macrophages in NASH.
Abstract: Macrophages are central to the pathogenesis of non-alcoholic steatohepatitis (NASH). However, the identities and functional relationships between tissue-resident and tissue-recruited macrophages in NASH remain poorly understood. A recent study from Seidman et al. (2020) elucidates, at single-cell resolution, the fates, niches, and regulatory landscapes of liver tissue-resident and tissue-recruited macrophage populations in NASH.
DOI: 10.1016/j.cmet.2020.08.005