Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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apoptosis1710 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A22491 | 24519272 | Hepatology | High-fat diet triggers Mallory-Denk body formation through misfolding and crosslinking of excess keratin 8. | 2014 | Details |
| A22555 | 24464605 | Hepatology | Reduced adiponectin signaling due to weight gain results in nonalcoholic steatohepatitis through impaired mitochondrial biogenesis. | 2014 | Details |
| A22573 | 24454937 | PLoS One | Lipid metabolism, oxidative stress and cell death are regulated by PKC delta in a dietary model of nonalcoholic steatohepatitis. | 2014 | Details |
| A22584 | 24445047 | J Nutr Biochem | Role of immunodeficient animal models in the development of fructose induced NAFLD. | 2013 | Details |
| A22620 | 24402912 | J Cell Biochem | HIF-1α expression as a protective strategy of HepG2 cells against fatty acid-induced toxicity. | 2014 | Details |
| A22633 | 24395441 | J Cell Physiol | Protective effect of the Y220C mutant p53 against steatosis: good news? | 2014 | Details |
| A22661 | 24377455 | Nutrition | Effects of bayberry juice on inflammatory and apoptotic markers in young adults with features of non-alcoholic fatty liver disease. | 2014 | Details |
| A22720 | 24358045 | Hepat Mon | How Much Weight Loss is Effective on Nonalcoholic Fatty Liver Disease? | 2013 | Details |
| A22753 | 24329600 | J Gastroenterol Hepatol | Attenuation of steatohepatitis, fibrosis, and carcinogenesis in mice fed a methionine-choline deficient diet by CCAAT/enhancer-binding protein homologous protein deficiency. | 2014 | Details |
| A22760 | 24325816 | BMB Rep | The expression and secretion of vimentin in the progression of non-alcoholic steatohepatitis. | 2014 | Details |
| A22781 | 24312613 | PLoS One | Pro-inflammatory activated Kupffer cells by lipids induce hepatic NKT cells deficiency through activation-induced cell death. | 2013 | Details |
| A22811 | 26202294 | Hepatol Int | An integrated view of liver injury and disease progression in nonalcoholic steatohepatitis. | 2013 | Details |
| A22820 | 24286856 | Metabolism | Palmitate-induced activation of mitochondrial metabolism promotes oxidative stress and apoptosis in H4IIEC3 rat hepatocytes. | 2013 | Details |
| A22822 | 24284796 | Am J Physiol Cell Physiol | Enhanced endoplasmic reticulum SERCA activity by overexpression of hepatic stimulator substance gene prevents hepatic cells from ER stress-induced apoptosis. | 2013 | Details |
| A22880 | 24258517 | Semin Immunopathol | CEACAM1 loss links inflammation to insulin resistance in obesity and non-alcoholic steatohepatitis (NASH). | 2013 | Details |
| A22881 | 24256559 | Liver Int | Mixed lineage kinase 3 deficient mice are protected against the high fat high carbohydrate diet-induced steatohepatitis. | 2013 | Details |
| A22883 | 24256086 | Am J Respir Crit Care Med | Obstructive sleep apnea syndrome affects liver histology and inflammatory cell activation in pediatric nonalcoholic fatty liver disease, regardless of obesity/insulin resistance. | 2014 | Details |
| A22906 | 24222092 | Semin Liver Dis | The role of gastrointestinal hormones in hepatic lipid metabolism. | 2013 | Details |
| A22919 | 24211274 | Toxicol Appl Pharmacol | CYP2E1-dependent and leptin-mediated hepatic CD57 expression on CD8+ T cells aid progression of environment-linked nonalcoholic steatohepatitis. | 2013 | Details |
| A22927 | 24205725 | Nihon Rinsho | [Pathophysiology of NAsh/NAFLD associated with high levels of serum triglycerides]. | 2013 | Details |
| A22937 | 24192698 | Pediatr Res | Developmental origins of nonalcoholic fatty liver disease. | 2013 | Details |
| A22954 | 24179614 | World J Hepatol | Lipotoxicity in the liver. | 2013 | Details |
| A22968 | 24161595 | Exp Mol Pathol | Manganese superoxide dismutase is reduced in the liver of male but not female humans and rodents with non-alcoholic fatty liver disease. | 2013 | Details |
| A22990 | 24132507 | Dig Dis Sci | Saturated free fatty acid sodium palmitate-induced lipoapoptosis by targeting glycogen synthase kinase-3β activation in human liver cells. | 2013 | Details |
| A22998 | 24126888 | Lab Invest | Excess iron modulates endoplasmic reticulum stress-associated pathways in a mouse model of alcohol and high-fat diet-induced liver injury. | 2013 | Details |
| A23012 | 24117897 | J Gastroenterol Hepatol | Effects of treatment with hydrogen sulfide on methionine-choline deficient diet-induced non-alcoholic steatohepatitis in rats. | 2014 | Details |
| A23031 | 24097666 | Toxicol Sci | The adaptive endoplasmic reticulum stress response to lipotoxicity in progressive human nonalcoholic fatty liver disease. | 2013 | Details |
| A23040 | 24084392 | J Chin Med Assoc | The involvement of NLRX1 and NLRP3 in the development of nonalcoholic steatohepatitis in mice. | 2013 | Details |
| A23062 | 24071521 | Life Sci | High-fat-cholesterol diet mainly induced necrosis in fibrotic steatohepatitis rat by suppressing caspase activity. | 2013 | Details |
| A23068 | 24067262 | Ann Hepatol | Adipocytokines and cytokeratin-18 in patients with nonalcoholic fatty liver disease: Introduction of CHA index. | 2014 | Details |
| A23076 | 24064383 | Free Radic Biol Med | CYP2E1 potentiates binge alcohol-induced gut leakiness, steatohepatitis, and apoptosis. | 2013 | Details |
| A23096 | 24042997 | Int J Mol Med | The chemical chaperon 4-phenylbutyric acid ameliorates hepatic steatosis through inhibition of de novo lipogenesis in high-fructose-fed rats. | 2013 | Details |
| A23126 | 24020820 | APMIS | Highly expressed MT-ND3 positively associated with histological severity of hepatic steatosis. | 2013 | Details |
| A23133 | 24015600 | Adv Clin Chem | Markers in nonalcoholic steatohepatitis. | 2013 | Details |
| A23141 | 24008361 | Am J Physiol Gastrointest Liver Physiol | Degradation of cIAPs contributes to hepatocyte lipoapoptosis. | 2013 | Details |
| A23178 | 23982157 | Am J Physiol Endocrinol Metab | Intracellular lipid content is a key intrinsic determinant for hepatocyte viability and metabolic and inflammatory states in mice. | 2013 | Details |
| A23189 | 23975340 | Dig Dis Sci | Cyclooxygenase-2 promotes hepatocellular apoptosis by interacting with TNF-α and IL-6 in the pathogenesis of nonalcoholic steatohepatitis in rats. | 2013 | Details |
| A23200 | 23965360 | Endocr J | Rosiglitazone attenuates casein-induced hepatic endoplasmic reticulum stress in Sprague-Dawley rats: a novel model of endoplasmic reticulum stress. | 2013 | Details |
| A23216 | 23951244 | PLoS One | Metformin protects rat hepatocytes against bile acid-induced apoptosis. | 2013 | Details |
| A23277 | 23905917 | J Allergy Clin Immunol | Innate sensors of pathogen and stress: linking inflammation to obesity. | 2013 | Details |
| A23290 | 23895854 | Nan Fang Yi Ke Da Xue Xue Bao | [Hepatocyte apoptosis and mitochondrial permeability transition pore opening in rats with nonalcoholic fatty liver]. | 2013 | Details |
| A23292 | 23894677 | PLoS One | Vismodegib suppresses TRAIL-mediated liver injury in a mouse model of nonalcoholic steatohepatitis. | 2013 | Details |
| A23313 | 23855299 | J Gastroenterol Hepatol | Non-alcoholic steatohepatitis: pathogenesis and novel therapeutic approaches. | 2013 | Details |
| A23324 | 23870449 | BMC Pediatr | Pediatric non alcoholic fatty liver disease: more on novel treatment targets. | 2013 | Details |
| A23336 | 23861709 | Evid Based Complement Alternat Med | Garlic-Derived S-Allylmercaptocysteine Ameliorates Nonalcoholic Fatty Liver Disease in a Rat Model through Inhibition of Apoptosis and Enhancing Autophagy. | 2013 | Details |
| A23349 | 23850676 | Biochem Biophys Res Commun | Propranolol, a β-adrenoceptor antagonist, worsens liver injury in a model of non-alcoholic steatohepatitis. | 2013 | Details |
| A23379 | 23832548 | Hepatology | M2 Kupffer cells promote M1 Kupffer cell apoptosis: a protective mechanism against alcoholic and nonalcoholic fatty liver disease. | 2013 | Details |
| A23455 | 23763294 | Alcohol Clin Exp Res | Genetic resistance to liver fibrosis on A/J mouse chromosome 17. | 2013 | Details |
| A23466 | 23755269 | PLoS One | Lepr(db/db) Mice with senescence marker protein-30 knockout (Lepr(db/db)Smp30(Y/-)) exhibit increases in small dense-LDL and severe fatty liver despite being fed a standard diet. | 2013 | Details |
| A23468 | 23752877 | Am J Gastroenterol | Serum cytokeratin-18 fragment levels are useful biomarkers for nonalcoholic steatohepatitis in children. | 2013 | Details |
| A23473 | 23747427 | Toxicol Lett | Impairment of reproductive function in a male rat model of non-alcoholic fatty liver disease and beneficial effect of N-3 fatty acid supplementation. | 2013 | Details |
| A23500 | 23721173 | J Transl Med | Molecular signature of adipose tissue in patients with both non-alcoholic fatty liver disease (NAFLD) and polycystic ovarian syndrome (PCOS). | 2013 | Details |
| A23510 | 25755488 | J Clin Exp Hepatol | Gut-liver axis: role of inflammasomes. | 2013 | Details |
| A23568 | 23666886 | Obesity (Silver Spring) | Dietary modification dampens liver inflammation and fibrosis in obesity-related fatty liver disease. | 2013 | Details |
| A23610 | 23627434 | Clin Sci (Lond) | Fetuin-A mRNA expression is elevated in NASH compared with NAFL patients. | 2013 | Details |
| A23614 | 23626003 | J Clin Endocrinol Metab | Circulating levels of FGF-21 in obese youth: associations with liver fat content and markers of liver damage. | 2013 | Details |
| A23633 | 23611112 | Clin Exp Pharmacol Physiol | A high-fat diet and multiple administration of carbon tetrachloride induces liver injury and pathological features associated with non-alcoholic steatohepatitis in mice. | 2013 | Details |
| A23639 | 23605066 | Pflugers Arch | Dietary capsaicin prevents nonalcoholic fatty liver disease through transient receptor potential vanilloid 1-mediated peroxisome proliferator-activated receptor δ activation. | 2013 | Details |
| A23681 | 23567086 | J Hepatol | Decoding cell death signals in liver inflammation. | 2013 | Details |
| A23682 | 23567085 | J Hepatol | Cannabinoid signaling and liver therapeutics. | 2013 | Details |
| A23704 | 23553630 | J Biol Chem | Metabolomic profiling reveals a role for caspase-2 in lipoapoptosis. | 2013 | Details |
| A23736 | 23519653 | Hepatol Int | Hepatic angiogenesis and fibrosis are common features in morbidly obese patients. | 2011 | Details |
| A23742 | 23516172 | World J Gastrointest Pharmacol Ther | Inhibition of apoptosis in the management of nonalcoholic fatty liver disease. | 2013 | Details |
| A23768 | 23500152 | J Hepatol | Pharmacological cholesterol lowering reverses fibrotic NASH in obese, diabetic mice with metabolic syndrome. | 2013 | Details |
| A23776 | 23489555 | Basic Clin Pharmacol Toxicol | Effects of antihypertensive and triglyceride lowering agents on splenocyte apoptosis in rats with fatty liver. | 2013 | Details |
| A23785 | 23482433 | Korean J Pediatr | Noninvasive diagnosis of pediatric nonalcoholic fatty liver disease. | 2013 | Details |
| A23786 | 23482247 | World J Gastroenterol | Fructose as a key player in the development of fatty liver disease. | 2013 | Details |
| A23795 | 23477499 | Antioxid Redox Signal | Peroxiredoxin 4 protects against nonalcoholic steatohepatitis and type 2 diabetes in a nongenetic mouse model. | 2013 | Details |
| A23800 | 23467489 | Lab Anim | Gender and strain-specific differences in the development of steatosis in rats. | 2013 | Details |
| A23812 | 23453039 | Metabolism | Involvement of regucalcin in lipid metabolism and diabetes. | 2013 | Details |
| A23858 | 23424927 | Rev Prat | [Treatment of nonalcoholic steatohepatitis]. | 2012 | Details |
| A23908 | 23394092 | Curr Pharm Des | Pathophysiology of NASH: perspectives for a targeted treatment. | 2013 | Details |
| A23975 | 23332087 | Hepatol Res | Liver and diabetes. A vicious circle. | 2013 | Details |
| A23987 | 23325576 | Hepatology | Hepatic reticuloendothelial system cell iron deposition is associated with increased apoptosis in nonalcoholic fatty liver disease. | 2013 | Details |
| A24000 | 23315648 | Z Gastroenterol | Non-alcoholic steatohepatitis occurs in celiac disease and is associated with cellular stress. | 2013 | Details |
| A24007 | 23305008 | Klin Lab Diagn | [The unity of pathogenesis of insulin resistance syndrome and non-alcoholic fatty disease of liver. The metabolic disorder of fatty acids and triglycerides]. | 2012 | Details |
| A24009 | 23304464 | J Obes | The relationship between nonalcoholic fatty liver disease and colorectal cancer: the future challenges and outcomes of the metabolic syndrome. | 2012 | Details |
| A24012 | 23303639 | Biofactors | Curcumin and liver disease. | 2013 | Details |
| A24018 | 23299969 | Hepatology | Free fatty acids repress small heterodimer partner (SHP) activation and adiponectin counteracts bile acid-induced liver injury in superobese patients with nonalcoholic steatohepatitis. | 2013 | Details |
| A24023 | 23296703 | J Immunol | Tim-3/galectin-9 regulate the homeostasis of hepatic NKT cells in a murine model of nonalcoholic fatty liver disease. | 2013 | Details |
| A24053 | 23276918 | Front Biosci (Landmark Ed) | Potential applications of miRNAs as diagnostic and prognostic markers in liver cancer. | 2013 | Details |
| A24055 | 23274901 | Diabetes | Sterol regulatory element-binding factor 2 (SREBF-2) predicts 7-year NAFLD incidence and severity of liver disease and lipoprotein and glucose dysmetabolism. | 2012 | Details |
| A24095 | 23233555 | Hematology Am Soc Hematol Educ Program | Gaucher disease and other storage disorders. | 2012 | Details |
| A24101 | 23227839 | Biomark Med | Serum biomarkers in nonalcoholic steatohepatitis: value for assessing drug effects? | 2012 | Details |
| A24122 | 23211317 | J Hepatol | Inhibition of p53 attenuates steatosis and liver injury in a mouse model of non-alcoholic fatty liver disease. | 2012 | Details |
| A24135 | 25755455 | J Clin Exp Hepatol | A Randomized Controlled Trial Comparing Efficacy of Pentoxifylline and Pioglitazone on Metabolic Factors and Liver Histology in Patients with Non-alcoholic Steatohepatitis. | 2012 | Details |
| A24144 | 23183522 | J Hepatol | Non-alcoholic steatohepatitis: the role of oxidized low-density lipoproteins. | 2012 | Details |
| A24148 | 23178552 | Prog Lipid Res | Molecular mechanisms and the role of saturated fatty acids in the progression of non-alcoholic fatty liver disease. | 2012 | Details |
| A24210 | 23118937 | PLoS One | Perinatal exposure to a high-fat diet is associated with reduced hepatic sympathetic innervation in one-year old male Japanese macaques. | 2012 | Details |
| A24257 | 23069937 | Lab Invest | Steatosis does not impair liver regeneration after partial hepatectomy. | 2012 | Details |
| A24261 | 23066946 | Aliment Pharmacol Ther | Assessment of non-alcoholic fatty liver disease using serum total cell death and apoptosis markers. | 2012 | Details |
| A24286 | 23038002 | J Toxicol Sci | Hepatoprotective effect of tamoxifen on steatosis and non-alcoholic steatohepatitis in mouse models. | 2012 | Details |
| A24309 | 24683373 | Gastroenterol Hepatol (N Y) | Noninvasive Diagnosis of NASH and Liver Fibrosis Within the Spectrum of NAFLD. | 2012 | Details |
| A24358 | 22970906 | Clin Sci (Lond) | NF-κB1 deficiency stimulates the progression of non-alcoholic steatohepatitis (NASH) in mice by promoting NKT-cell-mediated responses. | 2013 | Details |
| A24390 | 22941955 | Hepatology | Tumor necrosis factor receptor 1 gain-of-function mutation aggravates nonalcoholic fatty liver disease but does not cause insulin resistance in a murine model. | 2013 | Details |
| A24421 | 22914580 | AIDS | Autophagy inhibition due to thymidine analogues as novel mechanism leading to hepatocyte dysfunction and lipid accumulation. | 2012 | Details |
| A24424 | 22912545 | World J Gastroenterol | Overview and developments in noninvasive diagnosis of nonalcoholic fatty liver disease. | 2012 | Details |
| A24430 | 22902550 | J Hepatol | miR-34a/SIRT1/p53 is suppressed by ursodeoxycholic acid in the rat liver and activated by disease severity in human non-alcoholic fatty liver disease. | 2012 | Details |
| A24468 | 22864747 | Arch Pharm Res | Protective effects of gypenosides against fatty liver disease induced by high fat and cholesterol diet and alcohol in rats. | 2012 | Details |
| A24475 | 22857151 | Pharm Biol | Antioxidative effects of Alisma orientale extract in palmitate-induced cellular injury. | 2012 | Details |