Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A03849 | 33848277 | Clin Transl Gastroenterol | Diagnostic Performance of FibroTouch Ultrasound Attenuation Parameter and Liver Stiffness Measurement in Assessing Hepatic Steatosis and Fibrosis in Patients With Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A03850 | 33847462 | Hepatol Res | Meta-analysis of the effect of sodium-glucose cotransporter 2 inhibitors on hepatic fibrosis in patients with type 2 diabetes mellitus complicated with non-alcoholic fatty liver disease. | 2021 | Details |
| A03853 | 33846949 | Obes Surg | Gastric Bypass Compared with Sleeve Gastrectomy for Nonalcoholic Fatty Liver Disease: a Systematic Review and Meta-analysis. | 2021 | Details |
| A03857 | 33844174 | Obes Surg | Evolution of Non-alcoholic Fatty Liver Disease (NAFLD) Biomarkers in Response to Weight Loss 1 Year After Bariatric Surgery-a Post Hoc Analysis of the FibroTest Prospective Study. | 2021 | Details |
| A03865 | 33839905 | Eur J Nutr | Improving insulin sensitivity, liver steatosis and fibrosis in type 2 diabetes by a food-based digital education-assisted lifestyle intervention program: a feasibility study. | 2021 | Details |
| A03873 | 33837926 | Endocrine | Identification of transcriptomic signatures and crucial pathways involved in non-alcoholic steatohepatitis. | 2021 | Details |
| A03880 | 33834008 | Can J Gastroenterol Hepatol | Controlled Attenuation Parameter for Quantification of Steatosis: Which Cut-Offs to Use? | 2021 | Details |
| A03883 | 33833538 | Diabetes Metab Syndr Obes | The Association Between Different Obesity Phenotypes and Liver Fibrosis Scores in Elderly Individuals with Fatty Liver in Taiwan. | 2021 | Details |
| A03889 | 33832488 | Cell Commun Signal | Mild exacerbation of obesity- and age-dependent liver disease progression by senolytic cocktail dasatinib + quercetin. | 2021 | Details |
| A03892 | 33831474 | Adv Drug Deliv Rev | Lipid based nanocarriers for effective drug delivery and treatment of diabetes associated liver fibrosis. | 2021 | Details |
| A03895 | 33829368 | Adv Ther | Perspectives on Precision Medicine Approaches to NAFLD Diagnosis and Management. | 2021 | Details |
| A03900 | 33826669 | PLoS One | Two-dimensional shear wave elastography and ultrasound-guided attenuation parameter for progressive non-alcoholic steatohepatitis. | 2021 | Details |
| A03901 | 33825721 | Clin Transl Gastroenterol | Identification of High-Risk Patients With Nonalcoholic Fatty Liver Disease Using Noninvasive Tests From Primary Care and Endocrinology Real-World Practices. | 2021 | Details |
| A03905 | 33824248 | Korean J Gastroenterol | Efficacy and Safety of Biphenyl Dimethyl Dicarboxylate and Ursodeoxycholic Acid Combination in Chronic Hepatitis Related to Metabolic Syndrome Components. | 2021 | Details |
| A03906 | 33824122 | Pak J Pharm Sci | Antioxidant characteristics and hepatoprotective effects of a formula derived from Maydis stigma, Nelumbo nucifera and Taraxacum officinale against carbon tetrachloride-induced hepatic damage in rats. | 2020 | Details |
| A03909 | 33822817 | PLoS One | The relationship between liver histology and thyroid function tests in patients with non-alcoholic fatty liver disease (NAFLD). | 2021 | Details |
| A03910 | 33822497 | Int J Med Mushrooms | Bioactive Components and Possible Activities of Medicinal Mushrooms in Alleviating the Pathogenesis of Nonalcoholic Fatty Liver Disease (Review). | 2021 | Details |
| A03911 | 33822317 | Hepatol Int | Clinical and economic burden of nonalcoholic steatohepatitis in Saudi Arabia, United Arab Emirates and Kuwait. | 2021 | Details |
| A03912 | 33822104 | J Pharm Pharmacol | Eugenol modulates insulin sensitivity by upregulating insulin receptor substrate-2 in non-alcoholic fatty liver disease in rats. | 2021 | Details |
| A03919 | 33817364 | Heliyon | Inhaled exposure to air fresheners aggravated liver injury in a murine model of nonalcoholic fatty acid liver disease. | 2021 | Details |
| A03921 | 33816145 | World J Transplant | Noninvasive markers of liver steatosis and fibrosis after liver transplantation - Where do we stand? | 2021 | Details |
| A03922 | 33816022 | Cureus | Nonalcoholic Fatty Liver Disease and Fibrosis Risk in Patients With Obstructive Sleep Apnea: A Retrospective Analysis. | 2021 | Details |
| A03924 | 33815743 | Ther Adv Endocrinol Metab | Effect of sodium-glucose cotransporter 2 inhibitor in patients with non-alcoholic fatty liver disease and type 2 diabetes mellitus: a propensity score-matched analysis of real-world data. | 2021 | Details |
| A03927 | 33815606 | Exp Ther Med | Cytokines, paraoxonase-1, periostin and non-invasive liver fibrosis scores in patients with non-alcoholic fatty liver disease and persistently elevated aminotransferases: A pilot study. | 2021 | Details |
| A03935 | 33813276 | Biochem Biophys Res Commun | Hepatocytes derived increased SAA1 promotes intrahepatic platelet aggregation and aggravates liver inflammation in NAFLD. | 2021 | Details |
| A03938 | 33811766 | Hepatology | Cancer Risk in Patients With Biopsy-Confirmed Nonalcoholic Fatty Liver Disease: A Population-Based Cohort Study. | 2021 | Details |
| A03939 | 33811619 | Eat Weight Disord | Association of obstructive sleep apnea with non-alcoholic fatty liver disease in patients with obesity: an observational study. | 2021 | Details |
| A03941 | 33811369 | JPEN J Parenter Enteral Nutr | Body composition measured by bioelectrical impedance analysis is a viable alternative to magnetic resonance imaging in children with nonalcoholic fatty liver disease. | 2021 | Details |
| A03944 | 33810963 | Nutr Metab Cardiovasc Dis | Association between MBOAT7 rs641738 polymorphism and non-alcoholic fatty liver in overweight or obese children. | 2021 | Details |
| A03951 | 33809676 | J Clin Med | Caspase-Cleaved Keratin 18 Measurements Identified Ongoing Liver Injury after Bariatric Surgery. | 2021 | Details |
| A03953 | 33809062 | Mar Drugs | Fucoidan and Fucoxanthin Attenuate Hepatic Steatosis and Inflammation of NAFLD through Modulation of Leptin/Adiponectin Axis. | 2021 | Details |
| A03954 | 33808740 | Cancers (Basel) | A PDCD1 Role in the Genetic Predisposition to NAFLD-HCC? | 2021 | Details |
| A03959 | 33807927 | Nutrients | Ginseng Saponin Enriched in Rh1 and Rg2 Ameliorates Nonalcoholic Fatty Liver Disease by Inhibiting Inflammasome Activation. | 2021 | Details |
| A03960 | 33807699 | J Clin Med | The Role of the Transsulfuration Pathway in Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A03964 | 33807461 | Biomedicines | Hepatic Stellate Cell Activation and Inactivation in NASH-Fibrosis-Roles as Putative Treatment Targets? | 2021 | Details |
| A03969 | 33806428 | Cancers (Basel) | From Liver Fat to Cancer: Perils of the Western Diet. | 2021 | Details |
| A03971 | 33805893 | J Clin Med | Risk of Liver Fibrosis According to TSH Levels in Euthyroid Subjects. | 2021 | Details |
| A03972 | 33805795 | Nutrients | The Role of Resveratrol in Liver Disease: A Comprehensive Review from In Vitro to Clinical Trials. | 2021 | Details |
| A03973 | 33804956 | J Clin Med | Role of Angiogenesis in the Pathogenesis of NAFLD. | 2021 | Details |
| A03976 | 33804302 | J Clin Med | The Role of Diagnostic Biomarkers, Omics Strategies, and Single-Cell Sequencing for Nonalcoholic Fatty Liver Disease in Severely Obese Patients. | 2021 | Details |
| A03978 | 33803718 | Int J Mol Sci | Till Death Do Us Part-The Multifaceted Role of Platelets in Liver Diseases. | 2021 | Details |
| A03983 | 33802047 | J Clin Med | Natural History of NAFLD. | 2021 | Details |
| A03987 | 33800964 | Biology (Basel) | PNPLA3 Single Nucleotide Polymorphism Prevalence and Association with Liver Disease in a Diverse Cohort of Persons Living with HIV. | 2021 | Details |
| A03989 | 33800554 | Int J Mol Sci | The Role of CXCL16 in the Pathogenesis of Cancer and Other Diseases. | 2021 | Details |
| A03991 | 33799865 | Nutrients | A Positive Relationship between Betel Nut Chewing and Significant Liver Fibrosis in NAFLD Subjects, but Not in Non-NAFLD Ones. | 2021 | Details |
| A03994 | 33798658 | Magn Reson Imaging | Effect of hepatic steatosis on native T1 mapping of 3T magnetic resonance imaging in the assessment of T1 values for patients with non-alcoholic fatty liver disease. | 2021 | Details |
| A03999 | 33794784 | BMC Gastroenterol | A randomised placebo controlled trial of VSL#3® probiotic on biomarkers of cardiovascular risk and liver injury in non-alcoholic fatty liver disease. | 2021 | Details |
| A04000 | 33794741 | Autophagy | The ménage à trois of autophagy, lipid droplets and liver disease. | 2021 | Details |
| A04008 | 33790913 | Front Immunol | Group 3 Innate Lymphoid Cells Protect Steatohepatitis From High-Fat Diet Induced Toxicity. | 2021 | Details |
| A04013 | 33788613 | Environ Health Perspect | Effect of Epidermal Growth Factor Treatment and Polychlorinated Biphenyl Exposure in a Dietary-Exposure Mouse Model of Steatohepatitis. | 2021 | Details |
| A04016 | 33788377 | Liver Int | Elafibranor and liraglutide improve differentially liver health and metabolism in a mouse model of non-alcoholic steatohepatitis. | 2021 | Details |
| A04019 | 33787507 | Dis Model Mech | Modulation of serotonin in the gut-liver neural axis ameliorates the fatty and fibrotic changes in non-alcoholic fatty liver. | 2021 | Details |
| A04025 | 33785339 | Life Sci | A rapid juvenile murine model of nonalcoholic steatohepatitis (NASH): Chronic intermittent hypoxia exacerbates Western diet-induced NASH. | 2021 | Details |
| A04029 | 33784797 | Phytother Res | Isotschimgine alleviates nonalcoholic steatohepatitis and fibrosis via FXR agonism in mice. | 2021 | Details |
| A04030 | 33783746 | Adv Exp Med Biol | Prevention of NAFLD/NASH by Astaxanthin and β-Cryptoxanthin. | 2021 | Details |
| A04034 | 33782517 | Sci Rep | Non-alcoholic fatty liver disease in polycystic ovary syndrome women. | 2021 | Details |
| A04038 | 33780219 | J Clin Gastroenterol | Identifying Advanced Fibrosis in NAFLD Using Noninvasive Tests: A Systematic Review of Sequential Algorithms. | 2022 | Details |
| A04040 | 33779880 | Dig Dis Sci | Progression of Nonalcoholic Fatty Liver Disease-Associated Fibrosis in a Large Cohort of Patients with Type 2 Diabetes. | 2021 | Details |
| A04041 | 33779332 | Hum Exp Toxicol | Therapeutic effects of myocardin-related transcription factor A (MRTF-A) knockout on experimental mice with nonalcoholic steatohepatitis induced by high-fat diet. | 2021 | Details |
| A04049 | 33776490 | J Exp Pharmacol | Experimental and Investigational Targeted Therapies for the Management of Fibrosis in NASH: An Update. | 2021 | Details |
| A04051 | 33776366 | World J Gastroenterol | Ursodeoxycholic acid as a means of preventing atherosclerosis, steatosis and liver fibrosis in patients with nonalcoholic fatty liver disease. | 2021 | Details |
| A04055 | 33774058 | J Hepatol | Ceruloplasmin gene variants are associated with hyperferritinemia and increased liver iron in patients with NAFLD. | 2021 | Details |
| A04057 | 33773856 | Rev Gastroenterol Mex (Engl Ed) | Fibrosis assessment in patients with nonalcoholic fatty liver disease: Adherence to proposed algorithms and barriers to complying with them. | 2021 | Details |
| A04063 | 33772456 | Indian J Gastroenterol | Efficacy of combining pentoxiphylline and vitamin E versus vitamin E alone in non-alcoholic steatohepatitis- A randomized pilot study. | 2021 | Details |
| A04075 | 33769376 | Curr Opin Gastroenterol | The role of bariatric surgery in the management of nonalcoholic steatohepatitis. | 2021 | Details |
| A04076 | 33768700 | J Dtsch Dermatol Ges | Non-alcoholic fatty liver disease and psoriasis - is there a shared proinflammatory network? | 2021 | Details |
| A04077 | 33768585 | Hepatology | Tumor Necrosis Factor α-Induced Protein 8-Like 2 Alleviates Nonalcoholic Fatty Liver Disease Through Suppressing Transforming Growth Factor Beta-Activated Kinase 1 Activation. | 2021 | Details |
| A04082 | 33766233 | Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi | [Down-regulation of IL-25 accompanied by a decrease in the number of M2 macrophages in patients of non-alcoholic fatty liver disease with significant liver fibrosis]. | 2021 | Details |
| A04086 | 33765931 | BMC Gastroenterol | Economic burden of non-alcoholic steatohepatitis with significant fibrosis in Thailand. | 2021 | Details |
| A04088 | 33764550 | Aliment Pharmacol Ther | Liver stiffness by magnetic resonance elastography is associated with increased risk of cardiovascular disease in patients with non-alcoholic fatty liver disease. | 2021 | Details |
| A04089 | 33763391 | Can J Gastroenterol Hepatol | Liver and Nonliver-Related Outcomes at 2 Years Are Not Influenced by the Results of the FIB-4 Test and Liver Elastography in a Real-Life Cohort of Patients with Type 2 Diabetes. | 2021 | Details |
| A04092 | 33762835 | Diabetes Metab Syndr Obes | Clinical and Metabolic Characteristics of Non-Alcoholic Fatty Liver Disease Patients in Saudi Arabia: Data from the Systematic Observatory Liver Disease (SOLID) Registry. | 2021 | Details |
| A04102 | 33759300 | Diabetes Metab Res Rev | Advanced liver fibrosis and the metabolic syndrome in a primary care setting. | 2021 | Details |
| A04104 | 33757528 | Lipids Health Dis | Performance of liver stiffness measurements obtained with FibroScan is affected by glucose metabolism in patients with nonalcoholic fatty liver disease. | 2021 | Details |
| A04109 | 33754067 | Theranostics | NAD+-boosting therapy alleviates nonalcoholic fatty liver disease via stimulating a novel exerkine Fndc5/irisin. | 2021 | Details |
| A04114 | 33752128 | EBioMedicine | Conjugated secondary 12α-hydroxylated bile acids promote liver fibrogenesis. | 2021 | Details |
| A04118 | 33751289 | Eur J Health Econ | Disease burden and economic impact of diagnosed non-alcoholic steatohepatitis (NASH) in the United Kingdom (UK) in 2018. | 2021 | Details |
| A04126 | 33746906 | Front Endocrinol (Lausanne) | Ectodysplasin A Is Increased in Non-Alcoholic Fatty Liver Disease, But Is Not Associated With Type 2 Diabetes. | 2021 | Details |
| A04133 | 33746083 | J Hepatol | Prospective evaluation of the prevalence of non-alcoholic fatty liver disease and steatohepatitis in a large middle-aged US cohort. | 2021 | Details |
| A04137 | 33744378 | Diabetes Res Clin Pract | The prevalence of metabolic associated fatty liver detected by FibroScan® in women with gestational diabetes in a multiethnic population. | 2021 | Details |
| A04139 | 33744170 | Dig Liver Dis | Apolipoproteins and liver parameters optimize cardiovascular disease risk-stratification in nonalcoholic fatty liver disease. | 2021 | Details |
| A04140 | 33743586 | BMC Gastroenterol | Association of circulating adipsin with nonalcoholic fatty liver disease in obese adults: a cross-sectional study. | 2021 | Details |
| A04141 | 33743554 | Hepatology | Increased Adipose Tissue Fibrogenesis, Not Impaired Expandability, Is Associated With Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A04142 | 33743323 | Nutr Res | Severity of metabolic syndrome is greater among nonalcoholic adults with elevated ALT and advanced fibrosis. | 2020 | Details |
| A04146 | 33742318 | Curr Diab Rep | The Relationship Between Type 2 Diabetes, NAFLD, and Cardiovascular Risk. | 2021 | Details |
| A04148 | 33741024 | Diabetol Metab Syndr | Prevalence of non-alcoholic fatty liver disease and its associated factors in individuals with type 1 diabetes: a cross-sectional study in a tertiary care center in Brazil. | 2021 | Details |
| A04151 | 33740211 | Hepatol Int | Liver fibrosis scores and coronary atherosclerosis: novel findings in patients with stable coronary artery disease. | 2021 | Details |
| A04155 | 33739030 | Clin Lab | Serum Biglycan as a Diagnostic Marker for Non-Alcoholic Steatohepatitis and Liver Fibrosis. | 2021 | Details |
| A04160 | 33733575 | Biofactors | Quercetin prevents cadmium chloride-induced hepatic steatosis and fibrosis by downregulating the transcription of miR-21. | 2021 | Details |
| A04164 | 33731798 | Sci Rep | Quantitative, noninvasive MRI characterization of disease progression in a mouse model of non-alcoholic steatohepatitis. | 2021 | Details |
| A04177 | 33727164 | Clin Gastroenterol Hepatol | Effect of Endoscopic Bariatric and Metabolic Therapies on Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-analysis. | 2021 | Details |
| A04178 | 33726979 | Dig Liver Dis | Microbiome, fibrosis and tumor networks in a non-alcoholic steatohepatitis model of a choline-deficient high-fat diet using diethylnitrosamine. | 2021 | Details |
| A04179 | 33726778 | Chin Med | Hepatoprotective effect of Qushihuayu formula on non-alcoholic steatohepatitis induced by MCD diet in rat. | 2021 | Details |
| A04182 | 33724511 | Hepatology | Glycemic Control Predicts Severity of Hepatocyte Ballooning and Hepatic Fibrosis in Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A04186 | 33723340 | Sci Rep | Elevation of plasma tRNA fragments as a promising biomarker for liver fibrosis in nonalcoholic fatty liver disease. | 2021 | Details |
| A04187 | 33723094 | Saudi J Gastroenterol | Surveillance for hepatocellular carcinoma in patients with advanced liver fibrosis. | 2021 | Details |
| A04188 | 33722778 | Clin Res Hepatol Gastroenterol | Efficacy and safety of obeticholic acid in liver disease-A systematic review and meta-analysis. | 2021 | Details |
| A04189 | 33722690 | Mol Metab | Suppression of insulin-induced gene 1 (INSIG1) function promotes hepatic lipid remodelling and restrains NASH progression. | 2021 | Details |
| A04195 | 33720570 | Ter Arkh | [Clinical and prognostic value of metabolic disorders in non-alcoholic fatty liver disease]. | 2020 | Details |
| A04198 | 33720049 | J Clin Invest | VCAM-1: closing the gap between lipotoxicity and endothelial dysfunction in nonalcoholic steatohepatitis. | 2021 | Details |