Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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inflammatory5866 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A07409 | 32512191 | Biochim Biophys Acta Mol Basis Dis | Extracellular vesicles derived from fat-laden hepatocytes undergoing chemical hypoxia promote a pro-fibrotic phenotype in hepatic stellate cells. | 2020 | Details |
| A07410 | 32512072 | Toxicol Appl Pharmacol | Diosmin ameliorates inflammation, insulin resistance, and fibrosis in an experimental model of non-alcoholic steatohepatitis in rats. | 2020 | Details |
| A07430 | 32502637 | Pharmacol Res | Molecular mechanisms of hepatic insulin resistance in nonalcoholic fatty liver disease and potential treatment strategies. | 2020 | Details |
| A07449 | 32491288 | Physiol Int | Betanin effect on PPAR-α and SREBP-1c expression in NMRI mice model of steatohepatitis with fibrosis. | 2020 | Details |
| A07462 | 32485838 | Int J Mol Sci | The Role of Insulin Resistance and Diabetes in Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A07463 | 32485811 | Int J Mol Sci | Relevance of SIRT1-NF-κB Axis as Therapeutic Target to Ameliorate Inflammation in Liver Disease. | 2020 | Details |
| A07465 | 32485245 | Eur J Pharmacol | Glycyrrhetinic acid attenuates disturbed vitamin a metabolism in non-alcoholic fatty liver disease through AKR1B10. | 2020 | Details |
| A07475 | 32481590 | Cells | Deletion of Perilipin 5 Protects Against Hepatic Injury in Nonalcoholic Fatty Liver Disease via Missing Inflammasome Activation. | 2020 | Details |
| A07480 | 32478287 | Nat Metab | Resolution of NASH and hepatic fibrosis by the GLP-1R/GcgR dual-agonist Cotadutide via modulating mitochondrial function and lipogenesis. | 2020 | Details |
| A07482 | 32477115 | Front Pharmacol | Repositioning an Immunomodulatory Drug Vidofludimus as a Farnesoid X Receptor Modulator With Therapeutic Effects on NAFLD. | 2020 | Details |
| A07483 | 32477107 | Front Pharmacol | Gut-Derived Serotonin Contributes to the Progression of Non-Alcoholic Steatohepatitis via the Liver HTR2A/PPARγ2 Pathway. | 2020 | Details |
| A07493 | 32475638 | Biochem Biophys Res Commun | Fucoxanthin inhibits hepatic oxidative stress, inflammation, and fibrosis in diet-induced nonalcoholic steatohepatitis model mice. | 2020 | Details |
| A07498 | 32472585 | J Pathol | Sex-opposed inflammatory effects of 27-hydroxycholesterol are mediated via differences in estrogen signaling. | 2020 | Details |
| A07499 | 32472368 | AMB Express | Probiotic Bifidobacterium lactis V9 attenuates hepatic steatosis and inflammation in rats with non-alcoholic fatty liver disease. | 2020 | Details |
| A07507 | 32466319 | Int J Mol Sci | Liquid Biopsy for the Diagnosis of Viral Hepatitis, Fatty Liver Steatosis, and Alcoholic Liver Diseases. | 2020 | Details |
| A07512 | 32461992 | Biomed Res Int | Heme Oxygenase-1 Suppresses Wnt Signaling Pathway in Nonalcoholic Steatohepatitis-Related Liver Fibrosis. | 2020 | Details |
| A07525 | 32455208 | ACS Omega | Ginsenoside Rg1 Regulates Liver Lipid Factor Metabolism in NAFLD Model Rats. | 2020 | Details |
| A07526 | 32455155 | Regen Ther | Development of a non-alcoholic steatohepatitis model with rapid accumulation of fibrosis, and its treatment using mesenchymal stem cells and their small extracellular vesicles. | 2020 | Details |
| A07529 | 32454225 | Pharmacol Res | Therapeutic potential of genipin in various acute liver injury, fulminant hepatitis, NAFLD and other non-cancer liver diseases: More friend than foe. | 2020 | Details |
| A07540 | 32450460 | Prostaglandins Leukot Essent Fatty Acids | Omega-3 derivatives, specialized pro-resolving mediators: Promising therapeutic tools for the treatment of pain in chronic liver disease. | 2020 | Details |
| A07541 | 32450363 | Clin Gastroenterol Hepatol | Accuracy of Two-Dimensional Shear Wave Elastography and Attenuation Imaging for Evaluation of Patients With Nonalcoholic Steatohepatitis. | 2020 | Details |
| A07548 | 32446270 | Br J Pharmacol | Astaxanthin attenuates hepatic damage and mitochondrial dysfunction in non-alcoholic fatty liver disease by up-regulating the FGF21/PGC-1α pathway. | 2020 | Details |
| A07549 | 32446022 | Semin Arthritis Rheum | Safety of TNF inhibitors in rheumatic disease in case of NAFLD and cirrhosis. | 2020 | Details |
| A07559 | 32443660 | Nutrients | Gallic Acid Inhibits Lipid Accumulation via AMPK Pathway and Suppresses Apoptosis and Macrophage-Mediated Inflammation in Hepatocytes. | 2020 | Details |
| A07564 | 32442908 | Cytokine | Gastric banding-associated weight loss diminishes hepatic Tsukushi expression. | 2020 | Details |
| A07569 | 32440680 | Inflamm Bowel Dis | Multidimensional Impact of Mediterranean Diet on IBD Patients. | 2021 | Details |
| A07574 | 32439267 | Clin Nutr | Theaphenon E prevents fatty liver disease and increases CD4+ T cell survival in mice fed a high-fat diet. | 2020 | Details |
| A07576 | 32438122 | J Nutr Biochem | Resveratrol prevents liver damage in MCD-induced steatohepatitis mice by promoting SIGIRR gene transcription. | 2020 | Details |
| A07578 | 32437790 | Life Sci | Ginsenoside Rg1 protects against d-galactose induced fatty liver disease in a mouse model via FOXO1 transcriptional factor. | 2020 | Details |
| A07581 | 32436410 | Nutr Cancer | Combined Amelioration of Prebiotic Resveratrol and Probiotic Bifidobacteria on Obesity and Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A07588 | 32434697 | Transl Res | Cathepsin B deficiency ameliorates liver lipid deposition, inflammatory cell infiltration, and fibrosis after diet-induced nonalcoholic steatohepatitis. | 2020 | Details |
| A07597 | 32429849 | BMC Immunol | Anti-inflammatory activity of berberine in non-alcoholic fatty liver disease via the Angptl2 pathway. | 2020 | Details |
| A07600 | 32429478 | Cells | Exogenous Liposomal Ceramide-C6 Ameliorates Lipidomic Profile, Energy Homeostasis, and Anti-Oxidant Systems in NASH. | 2020 | Details |
| A07624 | 32416862 | Lancet Gastroenterol Hepatol | The effect of sleep on gastrointestinal functioning in common digestive diseases. | 2020 | Details |
| A07634 | 32413869 | Aging (Albany NY) | Overexpression of miR-142-5p inhibits the progression of nonalcoholic steatohepatitis by targeting TSLP and inhibiting JAK-STAT signaling pathway. | 2020 | Details |
| A07641 | 32411189 | PPAR Res | Loss of Hepatocyte-Specific PPARγ Expression Ameliorates Early Events of Steatohepatitis in Mice Fed the Methionine and Choline-Deficient Diet. | 2020 | Details |
| A07642 | 32411096 | Front Endocrinol (Lausanne) | Macrophage Subsets in Obesity, Aligning the Liver and Adipose Tissue. | 2020 | Details |
| A07647 | 32410294 | J Cell Mol Med | Magnesium isoglycyrrhizinate prevents the nonalcoholic hepatic steatosis via regulating energy homeostasis. | 2020 | Details |
| A07658 | 32406504 | Biosci Rep | Dysregulation of miR-192-5p in acute pancreatitis patients with nonalcoholic fatty liver and its functional role in acute pancreatitis progression. | 2020 | Details |
| A07663 | 32405177 | J Clin Exp Hepatol | NASH-inducing Diets in Göttingen Minipigs. | 2019 | Details |
| A07669 | 32401929 | Braz J Med Biol Res | A Brazilian regional basic diet-induced chronic malnutrition drives liver inflammation with higher ApoA-I activity in C57BL6J mice. | 2020 | Details |
| A07672 | 32398673 | Nat Commun | Hepatocyte mitochondria-derived danger signals directly activate hepatic stellate cells and drive progression of liver fibrosis. | 2020 | Details |
| A07681 | 32392712 | J Clin Med | A Role for Gut Microbiome Fermentative Pathways in Fatty Liver Disease Progression. | 2020 | Details |
| A07687 | 32390698 | World J Gastroenterol | Macrophages in metabolic associated fatty liver disease. | 2020 | Details |
| A07694 | 32389170 | Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi | [Inulin increases the proportion of monocytic myeloid-derived suppressor cells in peripheral blood, liver, spleen and regulates the secretion of plasma inflammatory cytokines in mice with non-alcoholic fatty liver disease]. | 2020 | Details |
| A07698 | 32387861 | Biomed Pharmacother | 2,3,5,4'-tetrahydroxystilbence-2-O-β-D-glucoside attenuates hepatic steatosis via IKKβ/NF-κB and Keap1-Nrf2 pathways in larval zebrafish. | 2020 | Details |
| A07699 | 32387461 | J Ethnopharmacol | Ginsenoside Mc1 improves liver steatosis and insulin resistance by attenuating ER stress. | 2020 | Details |
| A07701 | 32386798 | Clin Res Hepatol Gastroenterol | LUM is the hub gene of advanced fibrosis in nonalcoholic fatty liver disease patients. | 2020 | Details |
| A07709 | 32382414 | Biomed Rep | Diet induces hepatocyte protection in fatty liver disease via modulation of PTEN signaling. | 2020 | Details |
| A07718 | 32377366 | BMJ Open Gastroenterol | Antitumour necrosis factor-α agents and development of new-onset cirrhosis or non-alcoholic fatty liver disease: a retrospective cohort. | 2020 | Details |
| A07731 | 32373213 | Theranostics | PTPROt aggravates inflammation by enhancing NF-κB activation in liver macrophages during nonalcoholic steatohepatitis. | 2020 | Details |
| A07734 | 32372191 | Dig Dis Sci | G-Protein-Coupled Receptors 120 Agonist III Improves Hepatic Inflammation and ER Stress in Steatohepatitis. | 2020 | Details |
| A07736 | 32370702 | Protein Pept Lett | Adipokines: A Rainbow of Proteins with Metabolic and Endocrine Functions. | 2020 | Details |
| A07737 | 32370249 | Biology (Basel) | The Role of the Histone Methyltransferase EZH2 in Liver Inflammation and Fibrosis in STAM NASH Mice. | 2020 | Details |
| A07748 | 32365632 | Cells | L-Selectin/CD62L is a Key Driver of Non-Alcoholic Steatohepatitis in Mice and Men. | 2020 | Details |
| A07749 | 32365537 | Cells | EX-527 Prevents the Progression of High-Fat Diet-Induced Hepatic Steatosis and Fibrosis by Upregulating SIRT4 in Zucker Rats. | 2020 | Details |
| A07759 | 32362966 | Gastroenterology Res | Benefits of the Therapy With Abexol in Patients With Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
| A07760 | 32362329 | Prog Med Chem | P2X7 receptor antagonists for the treatment of systemic inflammatory disorders. | 2020 | Details |
| A07769 | 32360434 | J Hepatol | Differential effects of selective- and pan-PPAR agonists on experimental steatohepatitis and hepatic macrophages☆. | 2020 | Details |
| A07771 | 32360132 | Dig Liver Dis | Mitochondrial DNA from hepatocytes induces upregulation of interleukin-33 expression of macrophages in nonalcoholic steatohepatitis. | 2020 | Details |
| A07778 | 32357187 | PLoS One | Berberine inhibits free fatty acid and LPS-induced inflammation via modulating ER stress response in macrophages and hepatocytes. | 2020 | Details |
| A07781 | 32355844 | Ann Transl Med | The cellular pathways of liver fibrosis in non-alcoholic steatohepatitis. | 2020 | Details |
| A07814 | 32348835 | Life Sci | Exenatide ameliorates experimental non-alcoholic fatty liver in rats via suppression of toll-like receptor 4/NFκB signaling: Comparison to metformin. | 2020 | Details |
| A07816 | 32347583 | FASEB J | Aberrant glycosaminoglycan biosynthesis by tumor suppressor EXTL2 deficiency promotes liver inflammation and tumorigenesis through Toll-like 4 receptor signaling. | 2020 | Details |
| A07822 | 32344934 | J Clin Med | Lipidomics Reveals Reduced Inflammatory Lipid Species and Storage Lipids after Switching from EFV/FTC/TDF to RPV/FTC/TDF: A Randomized Open-Label Trial. | 2020 | Details |
| A07832 | 32341017 | J Pharmacol Exp Ther | 7α,25-Dihydroxycholesterol Suppresses Hepatocellular Steatosis through GPR183/EBI2 in Mouse and Human Hepatocytes. | 2020 | Details |
| A07840 | 32337855 | Mol Syst Biol | The acute effect of metabolic cofactor supplementation: a potential therapeutic strategy against non-alcoholic fatty liver disease. | 2020 | Details |
| A07853 | 32333910 | Gastroenterology | Role of Cannabis and Its Derivatives in Gastrointestinal and Hepatic Disease. | 2020 | Details |
| A07859 | 32331389 | Cells | The P2X7 Receptor and NLRP3 Axis in Non-Alcoholic Fatty Liver Disease: A Brief Review. | 2020 | Details |
| A07860 | 32331364 | Cells | The Emerging Role of MicroRNAs in NAFLD: Highlight of MicroRNA-29a in Modulating Oxidative Stress, Inflammation, and Beyond. | 2020 | Details |
| A07875 | 32326590 | Int J Mol Sci | Protein Deimination Signatures in Plasma and Plasma-EVs and Protein Deimination in the Brain Vasculature in a Rat Model of Pre-Motor Parkinson's Disease. | 2020 | Details |
| A07883 | 32323426 | Hepatol Res | Omics-derived hepatocellular carcinoma risk biomarkers for precision care of chronic liver diseases. | 2020 | Details |
| A07901 | 32317079 | BMB Rep | GPx7 ameliorates non-alcoholic steatohepatitis by regulating oxidative stress. | 2020 | Details |
| A07905 | 32316235 | J Clin Med | The Medium-Chain Fatty Acid Receptor GPR84 Mediates Myeloid Cell Infiltration Promoting Steatohepatitis and Fibrosis. | 2020 | Details |
| A07907 | 32315005 | Food Funct | Alleviating effects of noni fruit polysaccharide on hepatic oxidative stress and inflammation in rats under a high-fat diet and its possible mechanisms. | 2020 | Details |
| A07908 | 32314869 | J Cell Mol Med | Pro-inflammatory signalling and gut-liver axis in non-alcoholic and alcoholic steatohepatitis: Differences and similarities along the path. | 2020 | Details |
| A07917 | 32311490 | Free Radic Biol Med | Targeting DUSP7 signaling alleviates hepatic steatosis, inflammation and oxidative stress in high fat diet (HFD)-fed mice via suppression of TAK1. | 2020 | Details |
| A07920 | 32309365 | Ann Transl Med | Prolyl endopeptidase gene disruption attenuates high fat diet-induced nonalcoholic fatty liver disease in mice by improving hepatic steatosis and inflammation. | 2020 | Details |
| A07937 | 32304992 | Int Immunopharmacol | Role of pyroptosis in liver diseases. | 2020 | Details |
| A07943 | 32303170 | Curr Pharm Des | Hepatoprotective Effects of Resveratrol in Non-Alcoholic Fatty Live Disease. | 2021 | Details |
| A07946 | 32302970 | J Endocrinol | SCFAs alleviated steatosis and inflammation in mice with NASH induced by MCD. | 2020 | Details |
| A07959 | 32298766 | J Hepatol | Lytic cell death in metabolic liver disease. | 2020 | Details |
| A07962 | 32298459 | Histol Histopathol | Comparative analysis of the expression profiles of genes related to the Gadd45α signaling pathway in four kinds of liver diseases. | 2020 | Details |
| A07964 | 32297339 | Hepatology | Milk Fat Globule-Epidermal Growth Factor-Factor 8 Improves Hepatic Steatosis and Inflammation. | 2020 | Details |
| A07968 | 32295122 | Nutrients | Extra-Virgin Olive Oil from Apulian Cultivars and Intestinal Inflammation. | 2020 | Details |
| A07969 | 32294235 | Eur J Clin Invest | Macrophages in the pathophysiology of NAFLD: The role of sex differences. | 2020 | Details |
| A07980 | 32290942 | Wei Sheng Yan Jiu | [Effects of lycopene on metabolism of glycolipid and inflammation in non-alcoholic fatty liver disease rats]. | 2020 | Details |
| A07983 | 32290535 | Nutrients | Mediterranean Diet Nutrients to Turn the Tide against Insulin Resistance and Related Diseases. | 2020 | Details |
| A07985 | 32289885 | Cell Biochem Funct | Retinoic acid induced 16 deficiency exacerbates high-fat diet-induced steatohepatitis in mice. | 2020 | Details |
| A07997 | 32284043 | Lipids Health Dis | Orotic acid-treated hepatocellular carcinoma cells resist steatosis by modification of fatty acid metabolism. | 2020 | Details |
| A08000 | 32283406 | Environ Pollut | Long-term bisphenol S exposure aggravates non-alcoholic fatty liver by regulating lipid metabolism and inducing endoplasmic reticulum stress response with activation of unfolded protein response in male zebrafish. | 2020 | Details |
| A08006 | 32281563 | J Oleo Sci | Epigallocatechin Gallate Suppresses Inflammatory Responses by Inhibiting Toll-like Receptor 4 Signaling and Alleviates Insulin Resistance in the Livers of High-fat-diet Rats. | 2020 | Details |
| A08008 | 32281248 | Liver Int | Impact of osteopontin on the development of non-alcoholic liver disease and related hepatocellular carcinoma. | 2020 | Details |
| A08017 | 32279997 | Biochem Biophys Res Commun | Potential use of C-phycocyanin in non-alcoholic fatty liver disease. | 2020 | Details |
| A08035 | 32274342 | J Clin Transl Hepatol | COVID-19 and Liver Dysfunction: Current Insights and Emergent Therapeutic Strategies. | 2020 | Details |
| A08055 | 32267269 | Food Funct | A lupine (Lupinus angustifolious L.) peptide prevents non-alcoholic fatty liver disease in high-fat-diet-induced obese mice. | 2020 | Details |
| A08066 | 32258944 | Hepatol Commun | Pathogenesis of Nonalcoholic Steatohepatitis: An Overview. | 2020 | Details |
| A08074 | 32257903 | Lab Anim Res | Comparative study of liver injury induced by high-fat methionine- and choline-deficient diet in ICR mice originating from three different sources. | 2019 | Details |
| A08077 | 32256346 | Front Pharmacol | Hepatoprotective Effect of Cranberry Nutraceutical Extract in Non-alcoholic Fatty Liver Model in Rats: Impact on Insulin Resistance and Nrf-2 Expression. | 2020 | Details |
| A08095 | 32247823 | J Hepatol | Genome-wide and Mendelian randomisation studies of liver MRI yield insights into the pathogenesis of steatohepatitis. | 2020 | Details |