Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
stats1
stats2
stats3
stats4
Search for:
inflammatory5866 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A08098 | 32245940 | Med Sci Monit | Ganoderma Lucidum Polysaccharides Ameliorates Hepatic Steatosis and Oxidative Stress in db/db Mice via Targeting Nuclear Factor E2 (Erythroid-Derived 2)-Related Factor-2/Heme Oxygenase-1 (HO-1) Pathway. | 2020 | Details |
| A08102 | 32245585 | Chin J Nat Med | Fatty liver diseases, mechanisms, and potential therapeutic plant medicines. | 2020 | Details |
| A08104 | 32245205 | Int J Mol Sci | Combined Treatment with Sodium-Glucose Cotransporter-2 Inhibitor (Canagliflozin) and Dipeptidyl Peptidase-4 Inhibitor (Teneligliptin) Alleviates NASH Progression in A Non-Diabetic Rat Model of Steatohepatitis. | 2020 | Details |
| A08109 | 32244182 | Mol Metab | Impact of global PTP1B deficiency on the gut barrier permeability during NASH in mice. | 2020 | Details |
| A08114 | 32242391 | J Tradit Chin Med | Sini powder ameliorates the inflammatory response in rats with stress-induced non-alcoholic fatty liver disease by inhibiting the nuclear factor kappa-B / pyrin domain-containing protein 3 pathway. | 2020 | Details |
| A08115 | 32241197 | Expert Rev Gastroenterol Hepatol | Obeticholic acid for the treatment of nonalcoholic steatohepatitis. | 2020 | Details |
| A08119 | 32240652 | Biochem Pharmacol | Pyrvinium pamoate attenuates non-alcoholic steatohepatitis: Insight on hedgehog/Gli and Wnt/β-catenin signaling crosstalk. | 2020 | Details |
| A08125 | 32239031 | Chem Commun (Camb) | Simultaneous co-assembly of fenofibrate and ketoprofen peptide for the dual-targeted treatment of nonalcoholic fatty liver disease (NAFLD). | 2020 | Details |
| A08130 | 32235829 | Cell Death Dis | TNF-Receptor-1 inhibition reduces liver steatosis, hepatocellular injury and fibrosis in NAFLD mice. | 2020 | Details |
| A08144 | 32230953 | Nutrients | Inflammation in Primary and Metastatic Liver Tumorigenesis-Under the Influence of Alcohol and High-Fat Diets. | 2020 | Details |
| A08150 | 32228300 | Gut Microbes | Maternal sucralose intake alters gut microbiota of offspring and exacerbates hepatic steatosis in adulthood. | 2020 | Details |
| A08157 | 32223926 | Biochem Biophys Res Commun | Remdesivir attenuates high fat diet (HFD)-induced NAFLD by regulating hepatocyte dyslipidemia and inflammation via the suppression of STING. | 2020 | Details |
| A08158 | 32223569 | Arch Physiol Biochem | Crosstalk between kidney and liver in non-alcoholic fatty liver disease: mechanisms and therapeutic approaches. | 2020 | Details |
| A08162 | 32222944 | Indian J Gastroenterol | Correlation between insulin resistance and liver histology in patients with nonalcoholic steatohepatitis with and without obesity. | 2020 | Details |
| A08163 | 32222873 | Glycoconj J | Disruption of hepatocyte Sialylation drives a T cell-dependent pro-inflammatory immune tone. | 2020 | Details |
| A08165 | 32220662 | Atherosclerosis | Relationship of fibroblast growth factor 21 levels with inflammation, lipoproteins and non-alcoholic fatty liver disease. | 2020 | Details |
| A08166 | 32220583 | J Hepatol | MLKL-dependent signaling regulates autophagic flux in a murine model of non-alcohol-associated fatty liver and steatohepatitis. | 2020 | Details |
| A08176 | 32217808 | J Endocrinol | Hepatic inflammation precedes steatosis and is mediated by visceral fat accumulation. | 2020 | Details |
| A08180 | 32217109 | Chem Biol Interact | Familial non-alcoholic steatohepatitis leading to hepatocellular carcinoma. | 2020 | Details |
| A08183 | 32216545 | Tissue Eng Part B Rev | Fat-On-A-Chip Models for Research and Discovery in Obesity and Its Metabolic Comorbidities. | 2020 | Details |
| A08193 | 32211410 | Front Cell Dev Biol | Involvement of Nucleotide-Binding Oligomerization Domain-Like Receptor Family Pyrin Domain Containing 3 Inflammasome in the Pathogenesis of Liver Diseases. | 2020 | Details |
| A08195 | 32210914 | Front Endocrinol (Lausanne) | The Atypical Cannabinoid Abn-CBD Reduces Inflammation and Protects Liver, Pancreas, and Adipose Tissue in a Mouse Model of Prediabetes and Non-alcoholic Fatty Liver Disease. | 2020 | Details |
| A08200 | 32207804 | JAMA | Nonalcoholic Steatohepatitis: A Review. | 2020 | Details |
| A08220 | 32196885 | Liver Int | Non-amyloid liver involvement in familial Mediterranean fever: A systematic literature review. | 2020 | Details |
| A08223 | 32194141 | Immunol Lett | MiR-149 attenuates endoplasmic reticulum stress-induced inflammation and apoptosis in nonalcoholic fatty liver disease by negatively targeting ATF6 pathway. | 2020 | Details |
| A08234 | 32191577 | J Med Food | Eriocitrin Improves Adiposity and Related Metabolic Disorders in High-Fat Diet-Induced Obese Mice. | 2020 | Details |
| A08243 | 32190149 | Arch Med Sci | Identification of key pathways and genes in nonalcoholic fatty liver disease using bioinformatics analysis. | 2020 | Details |
| A08260 | 32184638 | Diabetes Metab Syndr Obes | Lower Levels of Circulating Adiponectin in Elderly Patients with Metabolic Inflammatory Syndrome: A Cross-Sectional Study. | 2020 | Details |
| A08276 | 32171530 | Biochem Biophys Res Commun | Liraglutide ameliorates obesity-related nonalcoholic fatty liver disease by regulating Sestrin2-mediated Nrf2/HO-1 pathway. | 2020 | Details |
| A08282 | 32170127 | Sci Rep | Western diet induces severe nonalcoholic steatohepatitis, ductular reaction, and hepatic fibrosis in liver CGI-58 knockout mice. | 2020 | Details |
| A08283 | 32169759 | Biomed Pharmacother | Gegen Qinlian Decoction abates nonalcoholic steatohepatitis associated liver injuries via anti-oxidative stress and anti-inflammatory response involved inhibition of toll-like receptor 4 signaling pathways. | 2020 | Details |
| A08298 | 32163832 | J Nutr Biochem | Housing condition-associated changes in gut microbiota further affect the host response to diet-induced nonalcoholic fatty liver. | 2020 | Details |
| A08300 | 32161545 | Front Pharmacol | Pathogenesis of Chronic Plaque Psoriasis and Its Intersection With Cardio-Metabolic Comorbidities. | 2020 | Details |
| A08306 | 32158445 | Front Immunol | CD47 Deficiency in Mice Exacerbates Chronic Fatty Diet-Induced Steatohepatitis Through Its Role in Regulating Hepatic Inflammation and Lipid Metabolism. | 2020 | Details |
| A08308 | 32158249 | Clin Exp Gastroenterol | Effect of Ginger Powder Supplementation in Patients with Non-Alcoholic Fatty Liver Disease: A Randomized Clinical Trial. | 2020 | Details |
| A08312 | 32156524 | Free Radic Biol Med | Role of oxidative stress in the pathogenesis of nonalcoholic fatty liver disease. | 2020 | Details |
| A08319 | 32153044 | J Gastroenterol Hepatol | Effect of weight loss induced by laparoscopic sleeve gastrectomy on liver histology and serum adipokine levels. | 2020 | Details |
| A08326 | 32151955 | Int Immunopharmacol | Anti-toll-like receptor 2 antibody ameliorates hepatic injury, inflammation, fibrosis and steatosis in obesity-related metabolic disorder rats via regulating MAPK and NF-κB pathways. | 2020 | Details |
| A08328 | 32151552 | Surg Obes Relat Dis | Management of nonalcoholic fatty liver disease and the role of bariatric surgery: a brief review for surgeons. | 2020 | Details |
| A08336 | 32149275 | JHEP Rep | Macrophages in obesity and non-alcoholic fatty liver disease: Crosstalk with metabolism. | 2019 | Details |
| A08346 | 32147075 | Complement Ther Med | Effects of curcuminoids on inflammatory status in patients with non-alcoholic fatty liver disease: A randomized controlled trial. | 2020 | Details |
| A08353 | 32145306 | Life Sci | Differential metabolic and hepatic transcriptome responses of two miniature pig breeds to high dietary cholesterol. | 2020 | Details |
| A08365 | 32143076 | Chemosphere | Differential mechanisms regarding triclosan vs. bisphenol A and fluorene-9-bisphenol induced zebrafish lipid-metabolism disorders by RNA-Seq. | 2020 | Details |
| A08378 | 32135539 | Dig Dis | Sarcopenia Is a New Risk Factor of Nonalcoholic Fatty Liver Disease in Patients with Inflammatory Bowel Disease. | 2020 | Details |
| A08380 | 32134732 | J Basic Clin Physiol Pharmacol | Silymarin: not just another antioxidant. | 2020 | Details |
| A08393 | 32128893 | J Gastroenterol Hepatol | Regulation of lipid-induced macrophage polarization through modulating peroxisome proliferator-activated receptor-gamma activity affects hepatic lipid metabolism via a Toll-like receptor 4/NF-κB signaling pathway. | 2020 | Details |
| A08396 | 32126269 | Biochim Biophys Acta Mol Basis Dis | Chemical hypoxia induces pro-inflammatory signals in fat-laden hepatocytes and contributes to cellular crosstalk with Kupffer cells through extracellular vesicles. | 2020 | Details |
| A08399 | 32124935 | Int J Mol Med | CYP4A11 is involved in the development of nonalcoholic fatty liver disease via ROS‑induced lipid peroxidation and inflammation. | 2020 | Details |
| A08401 | 32124686 | Curr Med Chem | The Effect of CB1 Antagonism on Hepatic Oxidative/Nitrosative Stress and Inflammation in Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A08402 | 32124651 | Expert Rev Gastroenterol Hepatol | The effects of epigenetic modification on the occurrence and progression of liver diseases and the involved mechanism. | 2020 | Details |
| A08404 | 32124221 | Obes Surg | Are Noninvasive Methods Comparable to Liver Biopsy in Postoperative Patients After Roux-en-Y Gastric Bypass? | 2020 | Details |
| A08438 | 32110624 | J Family Med Prim Care | Association of high-sensitivity C-reactive protein (hs-CRP) with non-alcoholic fatty liver disease (NAFLD) in Asian Indians: A cross-sectional study. | 2020 | Details |
| A08459 | 32103741 | BMC Gastroenterol | Fructo-oligosaccharides ameliorate steatohepatitis, visceral adiposity, and associated chronic inflammation via increased production of short-chain fatty acids in a mouse model of non-alcoholic steatohepatitis. | 2020 | Details |
| A08460 | 32103588 | Mol Nutr Food Res | Regulation of Adipocyte and Macrophage Functions by mTORC1 and 2 in Metabolic Diseases. | 2020 | Details |
| A08461 | 32102936 | Sci Transl Med | Liver macrophages inhibit the endogenous antioxidant response in obesity-associated insulin resistance. | 2020 | Details |
| A08462 | 32102237 | Int J Mol Sci | Molecular Mechanisms: Connections between Nonalcoholic Fatty Liver Disease, Steatohepatitis and Hepatocellular Carcinoma. | 2020 | Details |
| A08474 | 32096565 | Hepatology | Cardiolipin Synthase 1 Ameliorates NASH Through Activating Transcription Factor 3 Transcriptional Inactivation. | 2020 | Details |
| A08475 | 32096475 | Eur Cytokine Netw | Effect of folate supplementation on immunological and autophagy markers in experimental nonalcoholic fatty liver disease. | 2019 | Details |
| A08483 | 32092316 | Clin Chim Acta | Bnip3 in mitophagy: Novel insights and potential therapeutic target for diseases of secondary mitochondrial dysfunction. | 2020 | Details |
| A08490 | 32089754 | Dis Markers | Serum Golgi Protein 73 as a Potential Biomarker for Hepatic Necroinflammation in Population with Nonalcoholic Steatohepatitis. | 2020 | Details |
| A08499 | 32085637 | Nutrients | A Diterpenoid, 14-Deoxy-11, 12-Didehydroandrographolide, in Andrographis paniculata Reduces Steatohepatitis and Liver Injury in Mice Fed a High-Fat and High-Cholesterol Diet. | 2020 | Details |
| A08500 | 32084429 | Metabolism | mTORC1-dependent protein synthesis and autophagy uncouple in the regulation of Apolipoprotein A-I expression. | 2020 | Details |
| A08501 | 32084378 | Cell Metab | Targeting Hepatic Glutaminase 1 Ameliorates Non-alcoholic Steatohepatitis by Restoring Very-Low-Density Lipoprotein Triglyceride Assembly. | 2020 | Details |
| A08506 | 32083190 | Biochem Biophys Rep | Short-term high-fat diet intake leads to exacerbation of concanavalin A-induced liver injury through the induction of procoagulation state. | 2020 | Details |
| A08509 | 32081971 | Sci Rep | CCN1 promotes hepatic steatosis and inflammation in non-alcoholic steatohepatitis. | 2020 | Details |
| A08523 | 32075238 | Nutrients | Impact of the Co-Administration of N-3 Fatty Acids and Olive Oil Components in Preclinical Nonalcoholic Fatty Liver Disease Models: A Mechanistic View. | 2020 | Details |
| A08529 | 32071558 | Int J Biol Sci | Mesenchymal stromal cells promote liver regeneration through regulation of immune cells. | 2020 | Details |
| A08540 | 32068022 | Gastroenterology | Metabolic Inflammation-A Role for Hepatic Inflammatory Pathways as Drivers of Comorbidities in Nonalcoholic Fatty Liver Disease? | 2020 | Details |
| A08542 | 32067271 | Phytother Res | Effects of green tea or green tea catechin on liver enzymes in healthy individuals and people with nonalcoholic fatty liver disease: A systematic review and meta-analysis of randomized clinical trials. | 2020 | Details |
| A08558 | 32061598 | Gastroenterology | Adipose Tissue-Liver Cross Talk in the Control of Whole-Body Metabolism: Implications in Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A08560 | 32061596 | Gastroenterology | Therapeutic Landscape for NAFLD in 2020. | 2020 | Details |
| A08575 | 32054840 | Cell Death Dis | Antagonizing circRNA_002581-miR-122-CPEB1 axis alleviates NASH through restoring PTEN-AMPK-mTOR pathway regulated autophagy. | 2020 | Details |
| A08577 | 32054379 | J Recept Signal Transduct Res | Inevitable role of TGF-β1 in progression of nonalcoholic fatty liver disease. | 2020 | Details |
| A08582 | 32051820 | Can J Gastroenterol Hepatol | Natural History of Nonalcoholic Fatty Liver Disease: Implications for Clinical Practice and an Individualized Approach. | 2020 | Details |
| A08591 | 32047809 | Biomed Res Int | Recombinant Lactococcus lactis Expressing Ling Zhi 8 Protein Ameliorates Nonalcoholic Fatty Liver and Early Atherogenesis in Cholesterol-Fed Rabbits. | 2020 | Details |
| A08593 | 32046101 | Int J Mol Sci | Adaptation of Mitochondrial Substrate Flux in a Mouse Model of Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A08595 | 32045667 | Pharmacol Res | Human antigen R: A potential therapeutic target for liver diseases. | 2020 | Details |
| A08598 | 32044884 | Appl Immunohistochem Mol Morphol | Novel Interplay Between Sonic Hedgehog and Transforming Growth Factor-β1 in Human Nonalcoholic Steatohepatitis. | 2020 | Details |
| A08599 | 32044821 | Eur J Gastroenterol Hepatol | Non-alcoholic fatty liver disease in inflammatory bowel disease patients. | 2020 | Details |
| A08604 | 32044284 | Clin Res Hepatol Gastroenterol | Does adipose tissue inflammation drive the development of non-alcoholic fatty liver disease in obesity? | 2020 | Details |
| A08619 | 32039405 | JHEP Rep | A blocking monoclonal antibody to CCL24 alleviates liver fibrosis and inflammation in experimental models of liver damage. | 2020 | Details |
| A08622 | 32039394 | JHEP Rep | Endoscopic duodenal mucosal resurfacing improves glycaemic and hepatic indices in type 2 diabetes: 6-month multicentre results. | 2019 | Details |
| A08635 | 32037512 | Br J Pharmacol | P7C3-A20 alleviates fatty liver by shaping gut microbiota and inducing FGF21/FGF1, via the AMP-activated protein kinase/CREB regulated transcription coactivator 2 pathway. | 2020 | Details |
| A08655 | 32031871 | Am J Physiol Heart Circ Physiol | Gut microbiome of a porcine model of metabolic syndrome and HF-pEF. | 2020 | Details |
| A08657 | 32030821 | J Gastroenterol Hepatol | Aging exacerbates high-fat diet-induced steatohepatitis through alteration in hepatic lipid metabolism in mice. | 2020 | Details |
| A08671 | 32027126 | J Chem Inf Model | Discovery of Novel Peroxisome Proliferator-Activated Receptor α (PPARα) Agonists by Virtual Screening and Biological Evaluation. | 2020 | Details |
| A08681 | 32024509 | BMC Complement Med Ther | Structural modulation of gut microbiota during alleviation of non-alcoholic fatty liver disease with Gynostemma pentaphyllum in rats. | 2020 | Details |
| A08685 | 32022950 | J Eur Acad Dermatol Venereol | The role of the interleukin-23/Th17 pathway in cardiometabolic comorbidity associated with psoriasis. | 2020 | Details |
| A08687 | 32021375 | J Inflamm Res | Saturated Fatty Acids in Obesity-Associated Inflammation. | 2020 | Details |
| A08696 | 32019793 | mBio | Endotoxin Producers Overgrowing in Human Gut Microbiota as the Causative Agents for Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A08710 | 32015930 | Liver Res | The acidic pathway of bile acid synthesis: Not just an alternative pathway☆. | 2019 | Details |
| A08729 | 32008345 | Orv Hetil | [Effects of physical activity in nonalcoholic fatty liver disease]. | 2020 | Details |
| A08732 | 32007822 | J Nutr Biochem | Effects of (-)-epicatechin on the time course of the expression of perilipins in a diet-induced model of nonalcoholic steatohepatitis. | 2019 | Details |
| A08734 | 32007335 | Nutr Metab Cardiovasc Dis | Addition of fish oil to atherogenic high fat diet inhibited atherogenesis while olive oil did not, in LDL receptor KO mice. | 2019 | Details |
| A08741 | 32004929 | J Nutr Biochem | Advanced liver steatosis accompanies an increase in hepatic inflammation, colonic, secondary bile acids and Lactobacillaceae/Lachnospiraceae bacteria in C57BL/6 mice fed a high-fat diet. | 2020 | Details |
| A08747 | 32002713 | Inflammation | Mice Deficient in the IL-1β Activation Genes Prtn3, Elane, and Casp1 Are Protected Against the Development of Obesity-Induced NAFLD. | 2020 | Details |
| A08748 | 32001554 | Gut | Liver transcriptomics highlights interleukin-32 as novel NAFLD-related cytokine and candidate biomarker. | 2020 | Details |
| A08755 | 32000066 | Biomed Pharmacother | Scoparone improves hepatic inflammation and autophagy in mice with nonalcoholic steatohepatitis by regulating the ROS/P38/Nrf2 axis and PI3K/AKT/mTOR pathway in macrophages. | 2020 | Details |
| A08762 | 31997053 | Dig Dis Sci | Plasma Oxylipins Levels in Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A08767 | 31992752 | Sci Rep | Biomarker discovery for chronic liver diseases by multi-omics - a preclinical case study. | 2020 | Details |