Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin9623 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A06786 | 32746645 | Expert Rev Gastroenterol Hepatol | Clinical heterogeneity in patients with non-alcoholic fatty liver disease-associated hepatocellular carcinoma. | 2020 | Details |
| A06804 | 32738842 | J Assoc Physicians India | Study and Comparison of Metabolic Profile of Lean and Obese Subjects with Non Alcoholic Fatty Liver Disease. | 2020 | Details |
| A06805 | 32738448 | J Hepatol | Reduced Nogo expression inhibits diet-induced metabolic disorders by regulating ChREBP and insulin activity. | 2020 | Details |
| A06809 | 32738301 | Biochim Biophys Acta Mol Cell Biol Lipids | Palmitoleic acid reduces high fat diet-induced liver inflammation by promoting PPAR-γ-independent M2a polarization of myeloid cells. | 2020 | Details |
| A06815 | 32736956 | Nutr Metab Cardiovasc Dis | Elevated blood pressure, cardiometabolic risk and target organ damage in youth with overweight and obesity. | 2020 | Details |
| A06822 | 32734012 | Porto Biomed J | An albino mouse model of nonalcoholic fatty liver disease induced using high-fat liquid "Lieber-DeCarli" diet: a preliminary investigation. | 2020 | Details |
| A06824 | 32733933 | Biomed Res Int | Ginsenoside Rb1 Alleviated High-Fat-Diet-Induced Hepatocytic Apoptosis via Peroxisome Proliferator-Activated Receptor γ. | 2020 | Details |
| A06827 | 32733017 | Sci Rep | Determining the contribution of a high-fructose corn syrup formulation to hepatic glycogen synthesis during ad-libitum feeding in mice. | 2020 | Details |
| A06829 | 32731709 | Wiad Lek | Features of some anthropometric indices and indices of insulin resistance in patients with non-alcoholic steatohepatitis on the background of obesity and osteoarthritis. | 2020 | Details |
| A06831 | 32731119 | Cytokine | Osteocalcin and osteoprotegerin levels and their relationship with adipokines and proinflammatory cytokines in children with nonalcoholic fatty liver disease. | 2020 | Details |
| A06837 | 32729704 | Minerva Med | Ancient wheats: beneficial effects on insulin resistance. | 2020 | Details |
| A06843 | 32726654 | Eur J Pharmacol | Neuregulin 4 alleviates hepatic steatosis via activating AMPK/mTOR-mediated autophagy in aged mice fed a high fat diet. | 2020 | Details |
| A06847 | 32725157 | J Clin Endocrinol Metab | Pancreatic Steatosis Associates With Impaired Insulin Secretion in Genetically Predisposed Individuals. | 2020 | Details |
| A06851 | 32724031 | Minerva Gastroenterol Dietol | Helicobacter pylori and non-alcoholic fatty liver disease. | 2020 | Details |
| A06854 | 32721044 | FASEB J | Hepatic STAMP2 mediates recombinant FGF21-induced improvement of hepatic iron overload in nonalcoholic fatty liver disease. | 2020 | Details |
| A06876 | 32713378 | Br J Nutr | Higher flavonoid intake is associated with a lower progression risk of non-alcoholic fatty liver disease in adults: a prospective study. | 2020 | Details |
| A06877 | 32712601 | Aging (Albany NY) | Decreased autophagy and fuel switching occur in a senescent hepatic cell model system. | 2020 | Details |
| A06880 | 32712045 | Asian J Surg | Sleeve gastrectomy ameliorated high-fat diet (HFD)-induced non-alcoholic fatty liver disease and upregulated the nicotinamide adenine dinucleotide +/ Sirtuin-1 pathway in mice. | 2020 | Details |
| A06882 | 32711187 | Transl Res | The GLP-1R agonist liraglutide limits hepatic lipotoxicity and inflammatory response in mice fed a methionine-choline deficient diet. | 2020 | Details |
| A06886 | 32710190 | Diabetologia | Multi-layered epigenetic regulation of IRS2 expression in the liver of obese individuals with type 2 diabetes. | 2020 | Details |
| A06887 | 32709942 | Sci Rep | Prevalence and staging of non-alcoholic fatty liver disease among patients with heart failure with preserved ejection fraction. | 2020 | Details |
| A06888 | 32708435 | Nutrients | Baseline HOMA IR and Circulating FGF21 Levels Predict NAFLD Improvement in Patients Undergoing a Low Carbohydrate Dietary Intervention for Weight Loss: A Prospective Observational Pilot Study. | 2020 | Details |
| A06889 | 32708059 | Biomedicines | Depression and Cognitive Impairment-Extrahepatic Manifestations of NAFLD and NASH. | 2020 | Details |
| A06890 | 32708036 | Nutrients | The Importance of the Fatty Acid Transporter L-Carnitine in Non-Alcoholic Fatty Liver Disease (NAFLD). | 2020 | Details |
| A06896 | 32706083 | Eur Rev Med Pharmacol Sci | A targeted metabolomic profiling of plasma acylcarnitines in nonalcoholic fatty liver disease. | 2020 | Details |
| A06901 | 32704576 | Endocrinol Diabetes Metab | Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) for the management of nonalcoholic fatty liver disease (NAFLD): A systematic review. | 2020 | Details |
| A06908 | 32701508 | JCI Insight | Effects of tesamorelin on hepatic transcriptomic signatures in HIV-associated NAFLD. | 2020 | Details |
| A06912 | 32699301 | Sci Rep | Hyperglycemia-stimulating diet induces liver steatosis in sheep. | 2020 | Details |
| A06914 | 32699106 | BMJ Open Diabetes Res Care | Hepatic fat is a stronger correlate of key clinical and molecular abnormalities than visceral and abdominal subcutaneous fat in youth. | 2020 | Details |
| A06917 | 32698101 | Growth Horm IGF Res | Growth hormone ameliorates high glucose-induced steatosis on in vitro cultured human HepG2 hepatocytes by inhibiting de novo lipogenesis via ChREBP and FAS suppression. | 2020 | Details |
| A06924 | 32696189 | Metab Brain Dis | Melatonin regulates neurodegenerative complications associated with NAFLD via enhanced neurotransmission and cellular integrity: a correlational study. | 2020 | Details |
| A06925 | 32696080 | Clin Res Cardiol | NAFLD and cardiovascular diseases: a clinical review. | 2020 | Details |
| A06927 | 32695965 | JHEP Rep | Imaging and immunometabolic phenotyping uncover changes in the hepatic immune response in the early phases of NAFLD. | 2020 | Details |
| A06928 | 32695733 | Can J Gastroenterol Hepatol | Verification of the Nutritional and Dietary Factors Associated with Skeletal Muscle Index in Japanese Patients with Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A06934 | 32694515 | Sci Rep | The food contaminant deoxynivalenol provokes metabolic impairments resulting in non-alcoholic fatty liver (NAFL) in mice. | 2020 | Details |
| A06936 | 32694178 | Gut | Dietary cholesterol drives fatty liver-associated liver cancer by modulating gut microbiota and metabolites. | 2020 | Details |
| A06942 | 32691411 | Lipids | Alteration of Serum Phospholipid n-6 Polyunsaturated Fatty Acid Compositions in Nonalcoholic Fatty Liver Disease in the Japanese Population: A Cross-Sectional Study. | 2020 | Details |
| A06944 | 32690594 | J Lipid Res | Depletion of adipocyte sphingosine kinase 1 leads to cell hypertrophy, impaired lipolysis, and nonalcoholic fatty liver disease. | 2020 | Details |
| A06946 | 32690265 | Bioorg Med Chem | Structure-activity relationship studies for the development of inhibitors of murine adipose triglyceride lipase (ATGL). | 2020 | Details |
| A06950 | 32690054 | BMC Public Health | Insights from qualitative research on NAFLD awareness with a cohort of T2DM patients: time to go public with insulin resistance? | 2020 | Details |
| A06952 | 32688217 | J Nutr Biochem | Epigallocatechin gallate but not catechin prevents nonalcoholic steatohepatitis in mice similar to green tea extract while differentially affecting the gut microbiota. | 2020 | Details |
| A06953 | 32687983 | Environ Toxicol Pharmacol | Early microcystin-LR exposure-linked inflammasome activation in mice causes development of fatty liver disease and insulin resistance. | 2020 | Details |
| A06957 | 32687159 | J Clin Endocrinol Metab | Sex-Specific Metabolite Biomarkers of NAFLD in Youth: A Prospective Study in the EPOCH Cohort. | 2020 | Details |
| A06961 | 32685936 | Explor Med | Nonalcoholic fatty liver disease and portal hypertension. | 2020 | Details |
| A06964 | 32684985 | Diabetol Metab Syndr | NAFLD as a continuum: from obesity to metabolic syndrome and diabetes. | 2020 | Details |
| A06965 | 32684739 | World J Gastroenterol | Medications in type-2 diabetics and their association with liver fibrosis. | 2020 | Details |
| A06968 | 32683952 | Am J Physiol Gastrointest Liver Physiol | Knockout of sulfatase 2 is associated with decreased steatohepatitis and fibrosis in a mouse model of nonalcoholic fatty liver disease. | 2020 | Details |
| A06972 | 32682086 | Ann Hepatol | Hepatic transcriptome signature correlated with HOMA-IR explains early nonalcoholic fatty liver disease pathogenesis. | 2020 | Details |
| A06976 | 32679761 | Biomolecules | Untargeted Profiling of Bile Acids and Lysophospholipids Identifies the Lipid Signature Associated with Glycemic Outcome in an Obese Non-Diabetic Clinical Cohort. | 2020 | Details |
| A06977 | 32679195 | Arch Biochem Biophys | (-)-Epicatechin and the comorbidities of obesity. | 2020 | Details |
| A06978 | 32679144 | Life Sci | Oxymatrine alleviated hepatic lipid metabolism via regulating miR-182 in non-alcoholic fatty liver disease. | 2020 | Details |
| A06986 | 32671767 | Adv Exp Med Biol | Autophagy and Obesity and Diabetes. | 2020 | Details |
| A06990 | 32670822 | J Tradit Complement Med | The synergistic effect of Citrus bergamia and Cynara cardunculus extracts on vascular inflammation and oxidative stress in non-alcoholic fatty liver disease. | 2020 | Details |
| A06994 | 32668273 | Magn Reson Imaging | Noninvasive assessment of abdominal adipose tissues and quantification of hepatic and pancreatic fat fractions in type 2 diabetes mellitus. | 2020 | Details |
| A06997 | 32666779 | Pol Arch Intern Med | Nonalcoholic fatty liver disease and the risk of metabolic comorbidities: how to manage in clinical practice. | 2020 | Details |
| A07007 | 32660189 | Zhonghua Gan Zang Bing Za Zhi | [Pancreatoduodenectomy and non-alcoholic fatty liver disease]. | 2020 | Details |
| A07013 | 32657776 | J Clin Invest | AGER1 downregulation associates with fibrosis in nonalcoholic steatohepatitis and type 2 diabetes. | 2020 | Details |
| A07024 | 32654522 | Arch Physiol Biochem | The common variant of rs6214 in insulin like growth factor 1 (IGF1) gene: a potential protective factor for non-alcoholic fatty liver disease. | 2020 | Details |
| A07031 | 32651233 | J Biol Chem | From overnutrition to liver injury: AMP-activated protein kinase in nonalcoholic fatty liver diseases. | 2020 | Details |
| A07037 | 32649507 | Chin Med J (Engl) | Intestinal epithelial chemokine (C-C motif) ligand 7 overexpression protects against high fat diet-induced obesity and hepatic steatosis in mice. | 2020 | Details |
| A07040 | 32647367 | Eur J Clin Nutr | The efficacy of flaxseed and hesperidin on non-alcoholic fatty liver disease: an open-labeled randomized controlled trial. | 2020 | Details |
| A07044 | 32645536 | Cytokine | Combination of asprosin and adiponectin as a novel marker for diagnosing non-alcoholic fatty liver disease. | 2020 | Details |
| A07048 | 32643194 | Prenat Diagn | Perinatal exposure to maternal obesity: Lasting cardiometabolic impact on offspring. | 2020 | Details |
| A07049 | 32642003 | Theranostics | Current understanding of the role of Adipose-derived Extracellular Vesicles in Metabolic Homeostasis and Diseases: Communication from the distance between cells/tissues. | 2020 | Details |
| A07051 | 32640454 | Pharmacology | Molecular Study on the Potential Protective Effects of Bee Venom against Fructose-Induced Nonalcoholic Steatohepatitis in Rats. | 2020 | Details |
| A07053 | 32640105 | J Intern Med | A systems biology approach to understand gut microbiota and host metabolism in morbid obesity: design of the BARIA Longitudinal Cohort Study. | 2020 | Details |
| A07054 | 32639223 | Int J Vitam Nutr Res | Vitamin D levels are not associated with non-alcoholic fatty liver disease severity in a Brazilian population. | 2020 | Details |
| A07057 | 32638541 | J Cachexia Sarcopenia Muscle | Association between muscle strength and advanced fibrosis in non-alcoholic fatty liver disease: a Korean nationwide survey. | 2020 | Details |
| A07063 | 32636124 | Nutr Metab Cardiovasc Dis | Lower levels of plasma NT-proBNP are associated with higher prevalence of NASH in patients with biopsy-proven NAFLD. | 2020 | Details |
| A07069 | 32633873 | J Intern Med | Nonalcoholic fatty liver disease is associated with a decreased myocardial mechano-energetic efficiency. | 2020 | Details |
| A07072 | 32631678 | Rev Neurol (Paris) | Metabolic alterations in spinal and bulbar muscular atrophy. | 2020 | Details |
| A07082 | 32629394 | EBioMedicine | MBOAT7 down-regulation by genetic and environmental factors predisposes to MAFLD. | 2020 | Details |
| A07086 | 32628351 | J Diabetes Investig | Loss of metabolic flexibility as a result of overexpression of pyruvate dehydrogenase kinases in muscle, liver and the immune system: Therapeutic targets in metabolic diseases. | 2020 | Details |
| A07093 | 32626560 | Middle East J Dig Dis | Assessment of Genetic Aspects of Non-alcoholic Fatty Liver and Premature Cardiovascular Events. | 2020 | Details |
| A07094 | 32625166 | Front Endocrinol (Lausanne) | Serum Ferritin Correlates With Liver Fat in Male Adolescents With Obesity. | 2020 | Details |
| A07101 | 32622088 | Biochim Biophys Acta Mol Cell Biol Lipids | The "discovery" of lipid droplets: A brief history of organelles hidden in plain sight. | 2020 | Details |
| A07107 | 32621046 | Cardiovasc Drugs Ther | Prolonged-release pirfenidone prevents obesity-induced cardiac steatosis and fibrosis in a mouse NASH model. | 2021 | Details |
| A07109 | 32620521 | Dig Liver Dis | Suppression of high-fat diet-induced obesity-associated liver mitochondrial dysfunction by docosahexaenoic acid and hydroxytyrosol co-administration. | 2020 | Details |
| A07111 | 32619031 | Diabet Med | Mechanisms, screening modalities and treatment options for individuals with non-alcoholic fatty liver disease and type 2 diabetes. | 2020 | Details |
| A07112 | 32618656 | Am J Gastroenterol | Allogenic Fecal Microbiota Transplantation in Patients With Nonalcoholic Fatty Liver Disease Improves Abnormal Small Intestinal Permeability: A Randomized Control Trial. | 2020 | Details |
| A07124 | 32613718 | Diabetes Obes Metab | Vitamin D for treatment of non-alcoholic fatty liver disease detected by transient elastography: A randomized, double-blind, placebo-controlled trial. | 2020 | Details |
| A07128 | 32610115 | J Hepatol | Suboptimal reliability of liver biopsy evaluation has implications for randomized clinical trials. | 2020 | Details |
| A07134 | 32607879 | Methods Mol Biol | Liver Macrophage Isolation by Flow Cytometry Sorting. | 2020 | Details |
| A07136 | 32606885 | Clin Exp Gastroenterol | Effects of Aerobic Exercise Protocol on Genes Related to Insulin Resistance and Inflammation in the Pancreas of ob/ob Mice with NAFLD. | 2020 | Details |
| A07147 | 32603046 | Acta Gastroenterol Belg | A 3'-untranslated region variant (rs2289046) of insulin receptor substrate 2 gene is associated with susceptibility to nonalcoholic fatty liver disease. | 2020 | Details |
| A07148 | 32602214 | Hepatol Res | Clinical and anthropometric characteristics of non-obese non-alcoholic fatty liver disease subjects in Japan. | 2020 | Details |
| A07149 | 32599713 | Int J Mol Sci | Fructose and Uric Acid: Major Mediators of Cardiovascular Disease Risk Starting at Pediatric Age. | 2020 | Details |
| A07151 | 32598718 | Ter Arkh | [Features of the course of gallstone disease in patients with non-alcoholic fatty liver disease]. | 2020 | Details |
| A07152 | 32598715 | Ter Arkh | [Evaluation of the effectiveness of differentiated therapy of non-alcoholic fatty liver disease]. | 2020 | Details |
| A07153 | 32598639 | Ter Arkh | [Diabetes mellitus and chronic liver diseases. Part 1: general mechanisms of etiology and pathogenesis]. | 2019 | Details |
| A07157 | 32597705 | Am J Physiol Gastrointest Liver Physiol | Mitochondrial oxidative injury: a key player in nonalcoholic fatty liver disease. | 2020 | Details |
| A07158 | 32597296 | Autophagy | The unfolded protein response regulates hepatic autophagy by sXBP1-mediated activation of TFEB. | 2020 | Details |
| A07161 | 32595752 | Evid Based Complement Alternat Med | Adlay Seed (Coix lacryma-jobi L.) Extracts Exhibit a Prophylactic Effect on Diet-Induced Metabolic Dysfunction and Nonalcoholic Fatty Liver Disease in Mice. | 2020 | Details |
| A07166 | 32594969 | J Dev Orig Health Dis | Post-weaning exposure to high-sucrose diet induces early non-alcoholic fatty liver disease onset and progression in male mice: role of dysfunctional white adipose tissue. | 2020 | Details |
| A07167 | 32594797 | Hypertension | Nonalcoholic Fatty Liver Disease and Advanced Fibrosis in US Adults Across Blood Pressure Categories. | 2020 | Details |
| A07171 | 32593710 | Life Sci | Bisphenol-A exposure worsens hepatic steatosis in ovariectomized mice fed on a high-fat diet: Role of endoplasmic reticulum stress and fibrogenic pathways. | 2020 | Details |
| A07176 | 32592532 | Phytother Res | Sophoricoside is a selective LXRβ antagonist with potent therapeutic effects on hepatic steatosis of mice. | 2020 | Details |
| A07179 | 32592194 | Hepatology | iRhom2 Promotes Hepatic Steatosis by Activating MAP3K7-Dependent Pathway. | 2021 | Details |
| A07180 | 32591906 | Pflugers Arch | Glucose transporters in adipose tissue, liver, and skeletal muscle in metabolic health and disease. | 2020 | Details |
| A07188 | 32589264 | Eur J Clin Invest | COVID-19 and non-alcoholic fatty liver disease: Two intersecting pandemics. | 2020 | Details |