Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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oxidative stress3585 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A15283 | 28987868 | Redox Biol | Impairment of Akt activity by CYP2E1 mediated oxidative stress is involved in chronic ethanol-induced fatty liver. | 2017 | Details |
| A15285 | 28987260 | Clin Liver Dis | Treatment Strategies for Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis. | 2017 | Details |
| A15293 | 28982243 | J Agric Food Chem | Solanum nigrum Polyphenol Extracts Inhibit Hepatic Inflammation, Oxidative Stress, and Lipogenesis in High-Fat-Diet-Treated Mice. | 2017 | Details |
| A15296 | 28981157 | J Pineal Res | Effects of melatonin on fatty liver disease: The role of NR4A1/DNA-PKcs/p53 pathway, mitochondrial fission, and mitophagy. | 2017 | Details |
| A15302 | 28973994 | Nutrients | Silibinin Restores NAD⁺ Levels and Induces the SIRT1/AMPK Pathway in Non-Alcoholic Fatty Liver. | 2017 | Details |
| A15312 | 28971098 | Front Nutr | The Nutraceutic Silybin Counteracts Excess Lipid Accumulation and Ongoing Oxidative Stress in an In Vitro Model of Non-Alcoholic Fatty Liver Disease Progression. | 2017 | Details |
| A15319 | 28969511 | Stress | Interactive effects of chronic stress and a high-sucrose diet on nonalcoholic fatty liver in young adult male rats. | 2017 | Details |
| A15330 | 28964917 | Free Radic Biol Med | Redox imbalance due to the loss of mitochondrial NAD(P)-transhydrogenase markedly aggravates high fat diet-induced fatty liver disease in mice. | 2017 | Details |
| A15357 | 28948002 | Oncotarget | Linking atrial fibrillation with non-alcoholic fatty liver disease: potential common therapeutic targets. | 2017 | Details |
| A15367 | 28942443 | Cell Physiol Biochem | A Novel Role of SIRT1/ FGF-21 in Taurine Protection Against Cafeteria Diet-Induced Steatohepatitis in Rats. | 2017 | Details |
| A15374 | 28940752 | Mol Nutr Food Res | Supplementation with Docosahexaenoic Acid and Extra Virgin Olive Oil Prevents Liver Steatosis Induced by a High-Fat Diet in Mice through PPAR-α and Nrf2 Upregulation with Concomitant SREBP-1c and NF-kB Downregulation. | 2017 | Details |
| A15416 | 28923555 | J Am Soc Hypertens | Effects of chronic hepatitis C infection on arterial stiffness. | 2017 | Details |
| A15443 | 28904866 | FEBS Open Bio | IMM-H007, a new therapeutic candidate for nonalcoholic fatty liver disease, improves hepatic steatosis in hamsters fed a high-fat diet. | 2017 | Details |
| A15453 | 28900305 | Sci Rep | Berberine ameliorates fatty acid-induced oxidative stress in human hepatoma cells. | 2017 | Details |
| A15459 | 28895929 | Nutrients | Effects of Oral Administration of Silymarin in a Juvenile Murine Model of Non-alcoholic Steatohepatitis. | 2017 | Details |
| A15461 | 28895641 | Exp Clin Endocrinol Diabetes | Relationship between Oxidative Stress, Inflammation and Dyslipidemia with Fatty Liver Index in Patients with Type 2 Diabetes Mellitus. | 2017 | Details |
| A15476 | 28886991 | J Diabetes Complications | Molecular mechanisms of nonalcoholic fatty liver disease: Potential role for 12-lipoxygenase. | 2017 | Details |
| A15477 | 28886741 | BMC Complement Altern Med | Taurine and tea polyphenols combination ameliorate nonalcoholic steatohepatitis in rats. | 2017 | Details |
| A15491 | 28877979 | Gut | Fatty acids promote fatty liver disease via the dysregulation of 3-mercaptopyruvate sulfurtransferase/hydrogen sulfide pathway. | 2017 | Details |
| A15500 | 28874443 | J Lipid Res | Amelioration of diet-induced steatohepatitis in mice following combined therapy with ASO-Fsp27 and fenofibrate. | 2017 | Details |
| A15524 | 28862329 | J Sci Food Agric | Virgin coconut oil reverses hepatic steatosis by restoring redox homeostasis and lipid metabolism in male Wistar rats. | 2017 | Details |
| A15539 | 28853202 | Liver Int | Ursodeoxycholic acid: Effects on hepatic unfolded protein response, apoptosis and oxidative stress in morbidly obese patients. | 2017 | Details |
| A15541 | 28852433 | Oxid Med Cell Longev | Cytokines Genotype-Phenotype Correlation in Nonalcoholic Steatohepatitis. | 2017 | Details |
| A15558 | 28844958 | Biochim Biophys Acta Mol Basis Dis | Growth arrest and DNA damage-inducible 45α protects against nonalcoholic steatohepatitis induced by methionine- and choline-deficient diet. | 2017 | Details |
| A15577 | 28836404 | Cell J | Anti-Inflammatory Effects of Curcumin on Insulin Resistance Index, Levels of Interleukin-6, C-Reactive Protein, and Liver Histology in Polycystic Ovary Syndrome-Induced Rats. | 2017 | Details |
| A15579 | 28834687 | Appl Physiol Nutr Metab | Weight loss enhances hepatic antioxidant status in a NAFLD model induced by high-fat diet. | 2017 | Details |
| A15600 | 28820447 | Int J Mol Sci | Comprehensive Study of Multiple Stages Progressing to Nonalcoholic Steatohepatitis with Subsequent Fibrosis in SD Rats. | 2017 | Details |
| A15612 | 28811572 | Sci Rep | Inhibition of connexin hemichannels alleviates non-alcoholic steatohepatitis in mice. | 2017 | Details |
| A15618 | 28805669 | Nutrients | Effect of Mediterranean Diet and Antioxidant Formulation in Non-Alcoholic Fatty Liver Disease: A Randomized Study. | 2017 | Details |
| A15621 | 28804621 | Biomed Rep | Development of gene polymorphisms in meditators of nonalcoholic fatty liver disease. | 2017 | Details |
| A15643 | 28791501 | J Gastroenterol | Skeletal muscle mass to visceral fat area ratio is an important determinant affecting hepatic conditions of non-alcoholic fatty liver disease. | 2017 | Details |
| A15644 | 28790228 | Acta Med Indones | Association between Serum Uric Acid and Non-Alcoholic Fatty Liver Disease: A Meta-Analysis. | 2017 | Details |
| A15655 | 28781602 | Nutr Metab (Lond) | eIF2α phosphorylation is required to prevent hepatocyte death and liver fibrosis in mice challenged with a high fructose diet. | 2017 | Details |
| A15656 | 28777914 | Can J Physiol Pharmacol | Resveratrol improves high-fat diet induced fatty liver and insulin resistance by concomitantly inhibiting proteolytic cleavage of sterol regulatory element-binding proteins, free fatty acid oxidation, and intestinal triglyceride absorption. | 2017 | Details |
| A15687 | 28759733 | Can J Physiol Pharmacol | Protective effect of rimonabant, a canabinoid receptor 1 antagonist, on nonalcoholic fatty liver disease in a rat model through modulation of the hepatic expression of activin A and follistatin. | 2017 | Details |
| A15688 | 28759727 | Can J Physiol Pharmacol | The beneficial effects of resveratrol on steatosis and mitochondrial oxidative stress in HepG2 cells. | 2017 | Details |
| A15691 | 28759276 | J Diet Suppl | Biochemical and Histopathological Evidence on Beneficial Effects of Standardized Extract from Tragopogon graminifolius as a Dietary Supplement in Fatty Liver: Role of Oxidative Stress. | 2017 | Details |
| A15708 | 28750643 | Lipids Health Dis | Isolated hypercholesterolemia leads to steatosis in the liver without affecting the pancreas. | 2017 | Details |
| A15741 | 28734036 | Mol Nutr Food Res | (-)-Epicatechin regulates blood lipids and attenuates hepatic steatosis in rats fed high-fat diet. | 2017 | Details |
| A15746 | 28730823 | Physiol Res | Pathophysiological analysis of the progression of hepatic lesions in STAM mice. | 2017 | Details |
| A15759 | 28723568 | Cell Rep | Loss of Hepatic Mitochondrial Long-Chain Fatty Acid Oxidation Confers Resistance to Diet-Induced Obesity and Glucose Intolerance. | 2017 | Details |
| A15761 | 28723108 | Environ Sci Technol | Oral Exposure to Silver Nanoparticles or Silver Ions May Aggravate Fatty Liver Disease in Overweight Mice. | 2017 | Details |
| A15767 | 28720429 | Pharmacol Ther | Stable isotope-based flux studies in nonalcoholic fatty liver disease. | 2017 | Details |
| A15770 | 28718838 | Nutrients | Phyllanthus Niruri Standardized Extract Alleviates the Progression of Non-Alcoholic Fatty Liver Disease and Decreases Atherosclerotic Risk in Sprague-Dawley Rats. | 2017 | Details |
| A15777 | 28714405 | Curr Pharm Des | Emerging Targets to Relieve Fat Stress-Induced Liver Diseases: UDCA, Tocotrienol, ω-3 PUFAs, and IgY Targeted NPC1L1 Cholesterol Transporter. | 2017 | Details |
| A15784 | 28710554 | Obes Surg | Morphofunctional Changes After Sleeve Gastrectomy and Very Low Calorie Diet in an Animal Model of Non-Alcoholic Fatty Liver Disease. | 2018 | Details |
| A15812 | 28696785 | Arch Physiol Biochem | Exendin-4, a glucagon-like peptide-1 receptor agonist downregulates hepatic receptor for advanced glycation end products in non-alcoholic steatohepatitis rat model. | 2017 | Details |
| A15817 | 28695325 | Eur J Nutr | A modified response of NAFLD patients with non-significant fibrosis in nutritional counseling according to GCKR rs1260326. | 2017 | Details |
| A15819 | 28694655 | World J Gastroenterol | Antioxidant dietary approach in treatment of fatty liver: New insights and updates. | 2017 | Details |
| A15851 | 28680813 | FEBS Open Bio | Silencing of FABP1 ameliorates hepatic steatosis, inflammation, and oxidative stress in mice with nonalcoholic fatty liver disease. | 2017 | Details |
| A15853 | 28680292 | Curr Oncol | Effect of non-alcoholic liver disease on recurrence rate and liver regeneration after liver resection for colorectal liver metastases. | 2017 | Details |
| A15865 | 28676973 | Eur J Nutr | Chronic consumption of fructose in combination with trans fatty acids but not with saturated fatty acids induces nonalcoholic steatohepatitis with fibrosis in rats. | 2017 | Details |
| A15867 | 28676836 | Oxid Med Cell Longev | Genetic Nrf2 Overactivation Inhibits the Deleterious Effects Induced by Hepatocyte-Specific c-met Deletion during the Progression of NASH. | 2017 | Details |
| A15872 | 28676026 | Curr Vasc Pharmacol | A Critical Approach of Guideline Therapeutic Recommendations for NAFLD. | 2018 | Details |
| A15888 | 28670394 | Am J Transl Res | PFP alleviates nonalcoholic steatohepatitis fatty liver in both Apo E-/- mice and Changliver cell[S]. | 2017 | Details |
| A15892 | 28667519 | Sci China Life Sci | Retinoic acid ameliorates high-fat diet-induced liver steatosis through sirt1. | 2017 | Details |
| A15897 | 28664744 | Bratisl Lek Listy | Therapeutic effects of melatonin and quercetin in improvement of hepatic steatosis in rats through supression of oxidative damage. | 2017 | Details |
| A15920 | 28652650 | World J Gastroenterol | Role of non-steroidal anti-inflammatory drugs on intestinal permeability and nonalcoholic fatty liver disease. | 2017 | Details |
| A15921 | 28652427 | In Vivo | A Long-term Treatment with Silybin in Patients with Non-alcoholic Steatohepatitis Stimulates Catalase Activity in Human Endothelial Cells. | 2018 | Details |
| A15941 | 28642009 | Toxicol Lett | Mice in the early stage of liver steatosis caused by a high fat diet are resistant to thioacetamide-induced hepatotoxicity and oxidative stress. | 2017 | Details |
| A15955 | 28637594 | Metabolism | Association of plasma dipeptidyl peptidase-4 activity with non-alcoholic fatty liver disease in nondiabetic Chinese population. | 2017 | Details |
| A15956 | 28637520 | Br J Nutr | Citrulline decreases hepatic endotoxin-induced injury in fructose-induced non-alcoholic liver disease: an ex vivo study in the isolated perfused rat liver. | 2017 | Details |
| A15960 | 28637103 | Korean J Gastroenterol | [The Development of Hepatocellular Carcinoma in Non-alcoholic Fatty Liver Disease]. | 2017 | Details |
| A15961 | 28637102 | Korean J Gastroenterol | [The Progression of Liver Fibrosis in Non-alcoholic Fatty Liver Disease]. | 2017 | Details |
| A15963 | 28636830 | Appl Physiol Nutr Metab | Attenuation of hepatic steatosis by purple sweet potato colour is associated with blocking Src/ERK/C/EBPβ signalling in high-fat-diet-treated mice. | 2017 | Details |
| A15966 | 28635324 | Antioxid Redox Signal | Gliptins Suppress Inflammatory Macrophage Activation to Mitigate Inflammation, Fibrosis, Oxidative Stress, and Vascular Dysfunction in Models of Nonalcoholic Steatohepatitis and Liver Fibrosis. | 2017 | Details |
| A15972 | 28632197 | Nutrients | Toxic AGE (TAGE) Theory for the Pathophysiology of the Onset/Progression of NAFLD and ALD. | 2017 | Details |
| A15973 | 28632181 | Nutrients | Spirulina Protects against Hepatic Inflammation in Aging: An Effect Related to the Modulation of the Gut Microbiota? | 2017 | Details |
| A15979 | 28628674 | PLoS One | Hepatic microvascular dysfunction and increased advanced glycation end products are components of non-alcoholic fatty liver disease. | 2017 | Details |
| A15991 | 28623125 | Biochem Biophys Res Commun | Chronic intermittent hypoxia induces liver fibrosis in mice with diet-induced obesity via TLR4/MyD88/MAPK/NF-kB signaling pathways. | 2017 | Details |
| A16002 | 28618991 | Curr Med Chem | Effects of Polyphenolic Derivatives on Heme Oxygenase-System in Metabolic Dysfunctions. | 2018 | Details |
| A16019 | 28608557 | J Food Sci | Salicornia Extract Ameliorates Salt-Induced Aggravation of Nonalcoholic Fatty Liver Disease in Obese Mice Fed a High-Fat Diet. | 2017 | Details |
| A16023 | 28605664 | J Nutr Biochem | Soy compared with milk protein in a Western diet changes fecal microbiota and decreases hepatic steatosis in obese OLETF rats. | 2017 | Details |
| A16026 | 28603092 | Hepatobiliary Pancreat Dis Int | Crosstalk of liver immune cells and cell death mechanisms in different murine models of liver injury and its clinical relevance. | 2017 | Details |
| A16042 | 28596431 | Eur Respir J | Nonalcoholic fatty liver disease in chronic obstructive pulmonary disease. | 2017 | Details |
| A16045 | 28595552 | Curr Med Chem | Pigment Epithelium-Derived Factor: A Novel Therapeutic Target for Cardiometabolic Diseases and Related Complications. | 2018 | Details |
| A16047 | 28595079 | Int Immunopharmacol | Curcumin reduces the risk of chronic kidney damage in mice with nonalcoholic steatohepatitis by modulating endoplasmic reticulum stress and MAPK signaling. | 2017 | Details |
| A16061 | 28587303 | Children (Basel) | The Role of Lipid and Lipoprotein Metabolism in Non-Alcoholic Fatty Liver Disease. | 2017 | Details |
| A16073 | 28585211 | Adv Exp Med Biol | Non-Alcoholic Fatty Liver Disease. | 2017 | Details |
| A16074 | 28585204 | Adv Exp Med Biol | Insulin Resistance, Obesity and Lipotoxicity. | 2017 | Details |
| A16087 | 28577437 | Int Immunopharmacol | Rutin exhibits hepatoprotective effects in a mouse model of non-alcoholic fatty liver disease by reducing hepatic lipid levels and mitigating lipid-induced oxidative injuries. | 2017 | Details |
| A16095 | 28573069 | World J Gastrointest Pathophysiol | Combination curcumin and vitamin E treatment attenuates diet-induced steatosis in Hfe-/- mice. | 2017 | Details |
| A16119 | 28555525 | Immunopharmacol Immunotoxicol | Hepatoprotective effect of parthenolide in rat model of nonalcoholic fatty liver disease. | 2017 | Details |
| A16129 | 28549240 | J Nutr Biochem | Dietary salecan reverts partially the metabolic gene expressions and NMR-based metabolomic profiles from high-fat-diet-induced obese rats. | 2017 | Details |
| A16147 | 28539530 | Endocr J | Active form of vitamin D ameliorates non-alcoholic fatty liver disease by alleviating oxidative stress in a high-fat diet rat model. | 2017 | Details |
| A16152 | 28536120 | FASEB J | Hepatocyte-specific sirtuin 6 deletion predisposes to nonalcoholic steatohepatitis by up-regulation of Bach1, an Nrf2 repressor. | 2017 | Details |
| A16166 | 28527877 | Pharmacol Rep | Esculetin ameliorates hepatic fibrosis in high fat diet induced non-alcoholic fatty liver disease by regulation of FoxO1 mediated pathway. | 2017 | Details |
| A16169 | 28526925 | Eur J Nutr | Polyphenolic extract attenuates fatty acid-induced steatosis and oxidative stress in hepatic and endothelial cells. | 2017 | Details |
| A16177 | 28521680 | Curr Med Chem | Fatty Acids and Effects on In Vitro and In Vivo Models of Liver Steatosis. | 2019 | Details |
| A16186 | 28511733 | Nutr Res Rev | Similarities and interactions between the ageing process and high chronic intake of added sugars. | 2017 | Details |
| A16199 | 28508193 | Endocrine | Neutrophil depletion improves diet-induced non-alcoholic fatty liver disease in mice. | 2017 | Details |
| A16213 | 28504910 | J Med Food | Fermented Moringa oleifera Decreases Hepatic Adiposity and Ameliorates Glucose Intolerance in High-Fat Diet-Induced Obese Mice. | 2017 | Details |
| A16231 | 28496045 | J Atheroscler Thromb | Cholic Acid Enhances Visceral Adiposity, Atherosclerosis and Nonalcoholic Fatty Liver Disease in Microminipigs. | 2017 | Details |
| A16233 | 28494548 | Zhonghua Gan Zang Bing Za Zhi | [The role of cytochrome P450 in nonalcoholic fatty liver induced by high-fat diet: a gene expression profile analysis]. | 2017 | Details |
| A16238 | 28490707 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | [Effect of NF-κB on the pathogenic course of non-alcoholic fatty liver disease]. | 2017 | Details |
| A16245 | 28486193 | Biomed Pharmacother | Wogonin mitigates nonalcoholic fatty liver disease via enhancing PPARα/AdipoR2, in vivo and in vitro. | 2017 | Details |
| A16301 | 28468933 | J Endocrinol | The metabolic syndrome in mice overexpressing neuropeptide Y in noradrenergic neurons. | 2017 | Details |
| A16309 | 28465696 | J Res Med Sci | Pimpinella anisum L. fruit: Chemical composition and effect on rat model of nonalcoholic fatty liver disease. | 2017 | Details |
| A16319 | 28461774 | Korean J Physiol Pharmacol | Endogenous catalase delays high-fat diet-induced liver injury in mice. | 2017 | Details |
| A16322 | 28460180 | Can J Physiol Pharmacol | Role of folate in nonalcoholic fatty liver disease. | 2017 | Details |